Varicella Zoster Infection Treatment Market

Varicella Zoster Infection Treatment Market Snapshot

[276 Pages Report] The global Varicella Zoster Infection Treatment Market in 2020 is estimated for more than US$ 1.5 Bn and expected to reach a value of US$ 2.0 Bn by 2028 with a significant CAGR of 4.1%. As per Future Market Insights’ projections, in 2022, the acyclovir holds a substantial share of over 55.7% in the overall varicella zoster infection treatment market.

Human alphaherpesvirus 3, also known as Varicella Zoster virus (VZV) is one of the many herpesviruses that is known to infect humans. It is also the one causing infectious diseases like chicken pox (which is mostly common among children and teens) and herpes zoster (shingles) (mostly affecting adults but rarely in children). The growing incidence of herpes zoster (shingles) infection among the children’s and the elderly and the rising demand towards the treatment of the infection is aiding the growth of the market.

Market Outlook:

How The Market Progressed Till June 2022?

A comparative analysis about the market growth rates and development prospects in the global varicella zoster infection treatment market have been mapped by Future Market Insights. According to the FMI analysis, compared to H1-2021, the market is expected to decline by 16 Basis Point Share (BPS) in H1 2022 (O).

Major reasons for this dip in BPS are attributed to the adverse effects of antiviral therapy which include neurological, gastrointestinal stent, and renal toxicity. The market further observes a decline in 10 BPS in H1-2022 outlook as compared to H1-2022 projected period.

The market is subject to be influenced by regulatory guidelines and medical device approvals in accordance with impact of macro, economic, and industry factors. Prevention of varicella zoster infection through vaccination strategies permits the avoidance of primary infections in neonates and vulnerable cases. These are some of the significant breakthroughs in the varicella zoster infection treatment market.

Other market segments are correspondingly set to perform objectively and attain promising growth prospects in the next half of projection period. Additionally, there are some factors which positively drive the industry growth, including the improvement of cell medicated immunity after second administration of varicella vaccine, and long-lasting immunity response of live attenuated vaccines.

2016-2021 Varicella Zoster Infection Treatment Demand Outlook Compared to 2022-2028 Forecast

The Global varicella zoster infection treatment market is expected to grow at a modest rate during the forecast period. The epidemiology of the varicella infection is higher in children aged 4-10 year. However, Herpes zoster occur due to reactivation of varicella zoster virus in older age, where, the incidence is higher in older age population >60 years compared to adults and children.

For instance, in 2021, United States (US) reported that the risk of Herpes Zoster increases with age. A cumulative incidence of Herpes Zoster were reported to be from 2.9–19.5 cases per 1,000 population and an incidence rate of Herpes Zoster ranging from 5.23–10.9 cases per 1,000 person-years. It is been expected that the incidence of herpes zoster in these countries will increase with increasing older age population.

The Global Varicella Zoster Infection Treatment market constitutes nearly 3% of the ~52.7 Bn Antiviral Drugs Market, globally in 2021. Herpes zoster is not common in children younger than 1 year and is rarely found in children’ younger than 1 year. However, if a pregnant female witness’s varicella zoster infection during pregnancy, there are high chances of the fetus developing asymptomatic congenital infections. Such children generally present herpes zoster within the first year of their life. Furthermore, the growing risk of prenatal varicella zoster leads to the uptake of antiviral drugs treatment later in pregnancy. Thus, the growing risk of postnatal varicella zoster infection in children younger than 1 year of age and the subsequent use of acyclovir as the first line of treatment for these infected children will drive the growth of varicella zoster infection treatment market in future.

Hence, the demand outlook for varicella zoster infection treatment market is expected to grow rapidly during the forecast period from 2022- 2028 owing to the growing demand for effective drug treatments for varicella zoster infections.

The market is expected to expand at a considerable growth rate for the period 2022-2028 at a CAGR of approximately 4.1%, and observe an incremental $ opportunity of USD 438.6 Mn from 2022 to 2028. Demand for Acyclovir drug as a first line treatment will remain the maximum throughout the forecast period.

What are the Key Opportunities for Market Players?

The increasing incidences of viral borne disease among children and old population, high transmission rate of the infection, high occurrence of infections in low or middle-income countries and growing revenue of the market players are the major factors contributing to the growth of the varicella zoster infection treatment market.

The companies in the varicella zoster infection treatment market are focusing on organic and inorganic growth by launching their products and to gain maximum market share.  Moreover, acquisitions, expansion of product portfolio and research & development capabilities are expected to create opportunities for the growth of the market.

• For instance, in July 2021, US Food and Drug Administration (FDA) has approved Shingrix (Zoster Vaccine Recombinant, Adjuvanted) for the prevention of shingles (herpes zoster) in adults aged 18 years and older who are or who will be at increased risk of shingles due to immunodeficiency or immunosuppression.

Sabyasachi Ghosh

Principal Consultant

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What are the key challenges to Varicella Zoster Infection Treatment Market?

The adverse effect of anti-viral therapy treatment among the elderly population presents a biggest challenge for the market to grow ahead, the elderly care itself is an intensive care segment and onset of viral diseases like Herpes Zoster increases the risk of associated infections and other reactions.

Moreover, availability of other treatment options for treating the herpes zoster and varicella such as homeopathy, supplements and other natural herbal medicines may also come out as a bigger challenge for the varicella zoster infection treatment market. A clinical study done in China also revealed that the modified Gentiana formula when combined with the topical cream as a treatment for post-herpetic neuralgia, was more effective than the antiviral drugs treatment. Additionally, introduction of generic drugs by the local players in large number together with rising cases of product recalls of many such drugs are leading to create quality concern of these generic drugs amongst the consumers. All such factors together may pose greater challenges for the varicella zoster infection treatment market growth during the forecast period.

What is the Impact of the COVID-19 Crisis on the Market?

The COVID-19 outbreak initially affected the market negatively due to the lockdowns that were imposed in the first half of 2020, which resulted in disruption of the supply chain. Also, fall in number of surgeries and reduced patient visits to the hospitals due to change in healthcare priorities and also as a prevention measure to avoid contracting the disease also resulted in drop in the number of patients visiting hospitals for disease other than COVID-19.

However, with the opening of all the economies and the people now adapting to the new normal the market is been expected to achieve significant growth during the forecast period. Companies are revising their long-term strategies to develop adequate crisis-management strategies that place a premium on next-generation products and solutions, varicella zoster

Country-wise Insights

Will the U.S. Remain a Key Market for Varicella Zoster Infection Market?

The U.S. is the leading country of the North American region with a total market value share of 90.3% in 2021 and is projected to continue commanding the high growth during the coming years from 2022- 2028. The deep incidence of herpes infection among children mainly drives the growth of this market & their humanization and increasing pets disorder owing to rise in disease incidence.

For instance, as per Centre for Diseases Prevention and Control, an estimated one million cases of herpes zoster occur annually in the United States. The incidence for herpes zoster is approximately 4 cases per 1,000 U.S. population annually.

Additionally, presence of major players involved in the commercialization and development of herpes zoster interventions is also one of the major factor for the growth of this market in this region.

Why is Germany Considered a More Lucrative Market within Europe?

Germany dominates the Western Europe market of varicella zoster, with a share of nearly 24.7% of the market share by value in 2021. Similar growth is expected throughout the forecast period owing to the higher prevalence of herpes and increasing research and development activities which is also contributing to the varicella zoster infection treatment market growth in the region.  

For instance, the incidence of HZ in Germany ranges from about 1/1,000 in children aged less than 10 years, to more than 10/1,000 in persons aged 80 years and older; the incidence becomes distinctly higher in persons from 50 years onwards.

Why is Japan an Emerging Market for Varicella zoster infection treatment?

In 2021, Japan holds around 6.9% share in the global market by value and is been estimated to expand at a CAGR of 2.7% during the forecast period. The rising incidence of Herpes Zoster in the general population aged ≥ 50 or ≥ 60 years in the country leads to enhance the demand of varicella zoster infection treatment.

Additionally, rising government funding and support for vaccination and awareness campaigns are expected to propel the varicella zoster infection treatment market forward throughout the projection period.

What is the Outlook in China for the Varicella Zoster Infection Treatment Market?

In 2021, China has considerable share by value in the global market ranging around 8.7% and is been projected to expand at a CAGR of 4.5% from 2022-2028. This is predominantly due to the increasing risk of herpes zoster among the elderly population. Approximately, 32% of the Chinese population is aged 50 years and older and this proportion is increasing. Because of the ageing population, the public burden associated with shingles is been expected to increase over the time.

Category-wise Insights

Which Varicella Zoster Infection Treatment Product is driving the market growth?

By product, acyclovir drug accounts for the highest share of around 55.9% in 2021 and expected to expand at a CAGR of 3.7% during the forecast period from 2022 - 2028. 

Acyclovir presents the broader scope for the treatment of herpes zoster. It is also used to treat repeat outbreaks to prevent further outbreaks of genital herpes (a herpes virus infection that causes sores to form around the genitals and rectum from time to time) in people with a normal immune system. Famciclovir is also used to treat returning herpes simplex infections of the skin and mucus membranes (mouth, anus) in people with human immunodeficiency virus (HIV) infection

Owing to its broader benefits, the varicella zoster infection treatment market is experiencing its faster adoption, resulting in driving the demand for the drug in the varicella zoster infection treatment during the forecast period from 2022-2028.

Why does the Oral route of drug administration hold a High Market Share?

The Oral route for drug administration dominates the varicella zoster infection treatment market, with a 64.3% of the revenue share in 2021. This trend is expected to continue to grow during the study period. The high share of this segment is been attributed to its inherited safety, higher absorption and increased usage in the procedures and related treatment.

Which Distribution Channel is leading the Global Varicella Zoster Infection Treatment Market?

Based on the distribution channel, hospital pharmacies is the leading segment, with 43% market share in 2021 and expanding at a CAGR of 3.9% in the forecast period. Growing number of herpes zoster treatments in the hospitals and availability of medicines in the hospital pharmacies, as these medicines can only be bought if prescribed by a doctor or medical practitioner, will provide lucrative opportunities for varicella zoster infection treatment market growth.

Competitive Landscape

The key companies are focusing on regulatory approvals, new drug launches and marketing of their brands to get more attention and gain maximum market share. Additionally, acquisitions, mergers and strategic collaborations play a vital role in the growth of the varicella zoster infection treatment market.

• For Instance: In April 2017, Mylan Inc. announced that its subsidiary Mylan Pharmaceuticals has received final approval from the U.S. FDA for Acyclovir Ointment USP, 5%  is the first generic version of Valeant International's Zovirax Ointment
• In December 2016, Slayback and Sandoz signed an agreement for the sale and marketing rights of Slayback Generic Zovirax Ointment (Acyclovir Ointment). Due to the agreement, Novartis got the sale and marketing rights, which augmented their position in the market.

In Dec 2015, Valeant Pharmaceuticals International, Inc. announced new fulfillment agreements with Walgreens. Due to these agreements, the company forayed into retail business pharmacies

Scope of the Report

Varicella Zoster Infection Treatment - Market Segmentation - by Category

By Drug Type:

• Acyclovir
• Valacyclovir
• Famciclovir

By Route of Administration:

• Oral
• Injectable
• Topical

By Distribution Channel:

• Hospital pharmacies
• Retail Pharmacies
• Online Pharmacies
• Drug Stores

Region:

• North America
• Latin America
• Western Europe
• Eastern Europe
• APECJ
• China
• Japan
• Middle East Africa