Ulcerated Necrobiosis Lipoidica Management Market Snapshot (2023 to 2033)

The global ulcerated necrobiosis lipoidica management market is anticipated to attain an impressive valuation of USD 4.4 billion in 2023 and is projected to reach USD 7.9 billion by 2033, trailing a CAGR of 6.03% during the forecast period.

Growing incidences of diabetes as well as shift in urbanization and sedentary lifestyle, are key factors expected to fuel the Ulcerated Necrobiosis Lipoidica Management. Furthermore, improvements in technology in the field of diabetes as well as surging diabetic population is anticipated to propel market growth during the forecast period.

Growing prevalence of risk factors, for example diabetes, cancer, alcoholism, rising geriatric population, surging rate of bacterial infection and growing importance of research on diagnosis and treatment of rare diseases are some major factors that are anticipated to increase the growth and demand of the Global Necrotizing Fasciitis Market.

Report Attribute Details
Expected Market Value (2023) USD 4.4 billion
Anticipated Forecast Value (2033) USD 7.9 billion
Projected Growth Rate (2023 to 2033) CAGR 6.03%

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2018 to 2022 Ulcerated Necrobiosis Lipoidica management Demand Analysis vs. Forecast 2023 to 2033

The market for Ulcerated Necrobiosis Lipoidica was worth USD 3.5 billion in 2018, while growing at a CAGR of 4.68% during the historical period. Several factors like awareness in wellness and health, the diagnostic and pathology segment are getting a stronghold in the developing countries nowadays which is expected to fuel Ulcerated Necrobiosis Lipoidica treatment market. Moreover, the research and development activities in the field of emerging novel therapeutics is increasing the efficacy of medicine as well as treatment which is presenting growth opportunities for the targeted industry.

On the other hand, selling campaigns started by the global players is propelling the market upwards. Also, increasing focus by government organizations and private agencies such as WHO and pharmaceutical companies to create awareness of necrobiosis Lipoidica will benefit the market in the coming years.

In Addition, PCS499 is an oral emerging drug that is a deuterated analog of one of the major metabolites of pentoxifylline (PTX or Trental). It is currently being investigated for the treatment of Ulcerated Necrobiosis Lipoidica. PCS499 and its metabolites work by acting upon multiple pharmacological targets that are important in several conditions. The Food and drug administration granted Orphan Drug Designation for PCS499 for the treatment of necrobiosis lipoidica and seven years of Unites states exclusivity on the FDA approval. Considering these factors and new developments, the revenue growth of Ulcerated Necrobiosis Lipoidica treatment is projected to be worth USD 7.9 billion by end of the forecast period, while exhibiting a CAGR of 6.03%.

Which are Some Prominent Drivers spearheading the Ulcerated Necrobiosis Lipoidica Management Market?

Launch of new drugs expected to drive market growth

The increasing demand for effective cure indicated for necrobiosis lipoidica infections as current standard cure for these infections also involves surgical debridgement unfortunately leading to amputations which is expected to fuel market growth. To prevent loss of limb or fatal outcome, the need for novel therapies in Necrobiosis infections rises, which is anticipated to propel market growth during the forecast period. Also rapid discovery of novel therapy like hyperbaric oxygen therapy is further anticipated to augment revenue growth in this market during the forecast period.

Growth in advanced diagnostic techniques for diagnosis of necrobiosis lipoidica such as magnetic resonance imaging is contributing to market expansion of necrobiosis lipoidica treatment market. Furthermore, approval and launch of new medicines by leading companies is the other important factor augmenting growth of this market.

A vast number of drug candidates are in different stages of clinical trials in the United States and Europe. The expected launch and commercialization of these products is anticipated to fuel the global ulcerated necrobiosis lipoidica treatment market during the forecast period. Also, rising healthcare expenditure fuels demand for research and development of biologics and biosimilars for treatment of necrobiosis lipoidica which is expected to propel market growth in the forecast period.

Sabyasachi Ghosh
Sabyasachi Ghosh

Principal Consultant

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What are the challenges Projected to be Faced by the Market?

High cost and improper diagnosis restraining market expansion

Improver diagnosis of Ulcerated necrobiosis lipoidica disease is anticipated to challenge growth of this market, since initial symptoms are often mistaken for flu. High cost of treatment is also expected to hold back expansion of this market during the projected period.

Region-Wise Insights

What are the growth prospects in North America?

North America to dominate the market with maximum share

North America is anticipated to dominate the market of Ulcerated necrobiosis lipoidica treatment by accounting for 41% market share by end of the forecast period. The market in this region is projected to be worth more than USD 3.2 billion by 2033. The growth is attributable to increasing prevalence of necrobiosis lipoidica condition in this region. A study was conducted titled “ Development of a new critical pathway for treatment of acute skin structure infections under the clinical development for the drug ‘Dalbavancin’ from the allergen pharmaceutical in the unites states. These developments in this region will open up new opportunities for market expansion of Necrobiosis lipoidica.

On the other hand, an estimated 34.2 million people have diabetes (10.5 % of the United States population. Therefore, the risk of necrobiosis lipoidica diabectorum is anticipated to rise in the region and it will lead to market expansion.

The increasing product pipeline and product approval by regulatory authorities are anticipated to boost the market during the forecast period. For example, in July 2021, the Food and Drug Administration expanded the approval of Dalvance to include treatment of acute bacterial skin and skin structure infections caused by designated susceptible strains of Gram-positive microorganisms in pediatric patients. The treatment was only approved for adults 18 and older few years ago. In addition, in January 2022, Paladin Labs Inc., which is a subsidiary of Endo International plc developed and launched Xydalba (dalbavancin for injection), a 30-minute intravenous therapy in Canada for acute bacterial skin and skin structure infections that can be administered as a single- or two-dose regimen. These factors and developments will lead to market expansion in this region.

What is the growth outlook in Asia Pacific?

Asia Pacific market driving growth with fastest CAGR

The market of ulcerated necrobiosis lipoidica in Asia Pacific is estimated to witness fastest CAGR of 6.5% during the forecast period. This region is anticipated to possess 32.8% market share by end of 2033. Furthermore, market in this region will be worth more than USD 2.59 billion by end of the projected period. The growth in this region is attributed to rising prevalence of acute skin related and skin structure related disorders.

Furthermore, growing awareness, significant rise in healthcare spending and increasing frequency of Necrobiosis Lipoidica Diabeticorum in this region. Moreover, Asia Pacific is an emerging market owing to the increase in point of care approach in health and care. Also, growing number of hospitals in India and China makes a promising market for the treatment market across the globe.

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Category wise Insights

By Treatment Type, which segment will possess market dominance?

UVA1 Phototherapy segment driving growth with fastest CAGR

By treatment, UVA1 phototherapy is anticipated to reflect fastest CAGR of 6.8% during the forecast period. This segment is projected to account for 31% market share by end of the projected period. The growth is attributable to better efficacy offered by this therapy and growing prevalence of clinical trials on this method. The treatment by Phototherapy is treated as the first line therapy by the healthcare professionals.

Furthermore, this therapy has been proved to be the most successful therapy than methyl aminolevulinate (MAL)-photodynamic therapy, aminolevulinic acid-PDT, and psoralen plus ultraviolet-A (PUVA) with very less side-effects. Thus, these factors will lead to the fastest growth Ultraviolet A 1 phototherapy for the treatment of ulcerated necrobiosis lipoidica during the forecast period.

By end-user, which segment is expected to dominate the market?

Hospitals pushing growth with significant market share

The hospital segment dominated the market of Ulcerated Necrobiosis Lipoidica in 2022, with a market share of 59% . This segment is anticipated to retain its dominance by accounting for more than 71% market share by end of the forecast period. This segment will grow with a CAGR of 5.7% during the projected period. The factors that can be attributed to growth of this segment such as ease of interaction with prescribers and other health professionals are fuelling the demand for this segment.

Start-ups in Ulcerated Necrobiosis Lipoidica Management Market

Start-ups help in understanding the growth opportunities and prospects in any industry. These new businesses have the potential to generate high returns which directly benefits the growth of any industry. These start-ups are naturally more efficient at transforming inputs into outputs with more flexibility and adaptability in nature, able to shift quickly in response to volatile market conditions. Some of the start-ups that will augment the expansion of Ulcerated Necrobiosis Lipoidica Management Market are:

  • Bird Medical Devices is an India based company, which was founded in 2009. This company manufactures Hyperbaric Therapy Oxygen Therapy Chambers for human as well as for veterinary applications. The company's products include Monoplace Hyperbaric Oxygen Therapy Chamber, Multiplace Hyperbaric Oxygen Therapy Chamber, Portable Hyperbaric chamber, and Veterinary hyperbaric chamber to suit standalone Hyperbaric centers to big sized hospital facilities. Hyperbaric oxygen therapy refers to intermittent treatment of the entire body with 100-percent oxygen at higher than normal atmospheric pressures. Hyperbaric Oxygen Therapy plays a significant role in the treatment of Decompression illnesses, Arterial gas embolism, Ischemic wounds, Myonecrosis, Necrotising fasciitis, Radiation injuries etc.
  • Atox Bio is a Chapel Hill, United States-based start-up that is creating immunomodulators for the treatment of rare diseases. The company provides therapeutics solution for patients with necrotizing soft tissue Infections (flesh-eating bacteria), a rare, life-threatening infection. The leading candidate is AB103 which is studied in ACCUTE (AB103 clinical composite endpoint study in necrotizing soft Tissue Infections). It is in clinical trial phase 3. This drug received orphan drug designation from the food and drug administration and EMA and Fast Track designation. It was granted funding of USD 59.3 million from Arix Bioscience, Adams Street Partners, SR One, Orbimed, Esperante and 6 others.
  • CUTISS is a Zurich, Switzerland-based start-up that was founded in 2017. This start-up offers skin grafts for treatment of burns, cuts and damaged skin caused due to Necrobiosis Lipoidica. A part of the skin is collected from the patients to create skin graft. It works by combining with a hydrogel to create a dermo-epidermal graft. It causes minimal scaring after placing of the graft. They are currently conducting phase II clinical trials. This company received funding of USD 28 million from Giammaria Giuliani, Wyss Foundation, Yellowstone Holding and 9 Other Investors.

Market Competition

The ulcerated necrobiosis lipoidica management market is intensely competitive and consists of numerous key market players. These key players are developing novel delivery systems for treating ulcerated necrobiosis lipoidica. This is estimated to fuel Ulcerated Necrobiosis Lipoidica Management Market. The key players in this market are: Astellas Pharma, Vibcare Pharma, Pfizer, Manus Aktteva Biopharma LLP, Mylan Pharmaceuticals Inc., Upsher-Smith Laboratories, Novartis, Sanofi, Merck, GlaxoSmithKline

Key industry players are inclined on adoption of inorganic growth strategies like acquisition, mergers, partnerships, and collaboration in order to strengthen their product portfolio. This is anticipated to fuel the global Uulcerated necrobiosis lipoidica management market.

  • In June 2022, Basilea Pharmaceutica Ltd declared positive topline results for the Phase III ERADICATE study, evaluating ceftobiprole in treating adult patients with bacterial bloodstream infections caused by Staphylococcus aureus.
  • In January 2022, Paladin Labs Inc., which is a subsidiary of Endo International PLC announced the launch of ‘Xydalba’ (dalbavancin for injection), a 30-minute intravenous therapy for acute bacterial skin structure infections that can be administered as a single- or two-dose.
  • On July 7, 2021, Melinta Therapeutics, a pharmaceutical company, announced about launch of its product ‘KIMYRSA’. This drug is a lipoglycopeptide antibiotic that provide a complete course of treatment for chronic bacterial skin and skin structure infections. KIMYRSA is effective in a single dose of 1200mg injection.

Report Scope

Report Attribute Details
Market Value in 2023 USD 4.4 billion
Market Value in 2033 USD 7.9 billion
Growth Rate CAGR of 6.03 % from 2023 to 2033
Base Year for Estimation 2022
Historical Data 2018 to 2022
Forecast Period 2023 to 2033
Quantitative Units Revenue in USD Billion and CAGR from 2023 to 2033
Report Coverage Revenue Forecast, Volume Forecast, Company Ranking, Competitive Landscape, Growth Factors, Trends and Pricing Analysis
Segments Covered By treatment, By end-user, By Region
Regions Covered North America; Latin America; Europe; Asia Pacific; Middle East and Africa
Key Countries Profiled United States, Canada, Brazil, Mexico, Germany, United Kingdom, France, Spain, Italy, India, China, Japan, South Korea, Indonesia, Singapore, Thailand, Australia, New Zealand, GCC Countries, South Africa, Israel
Key Companies Profiled Astellas Pharma; Vibcare Pharma; Pfizer Inc.; Manus Aktteva Biopharma LLP; Mylan Pharmaceuticals Inc.; Upsher-Smith Laboratories; Novartis AG; Sanofi S.A; Merck & Co. Inc.; GSK Plc.
Customization Available Upon Request

Key Segments Profiled in the Ulcerated Necrobiosis Lipoidica Management Industry Survey

By Treatment:

  • Skin Grafting
  • Photodynamic Therapy
  • UVA1 Phototherapy
  • Topical Psoralen-UVA Therapy
  • Drugs
    • Antimalarial Agents
    • Antitubercular Agents
    • Immunosuppressive Agents
    • Hemorrheologic Agents
    • Fumaric Acid Esters
    • Calcineurin Inhibitors
    • Corticosteroids

By End User:

  • Hospitals
  • Specialty Clinics
  • Others

By Region:

  • North America
  • Latin America
  • Europe
  • Asia Pacific
  • Middle East and Africa

Frequently Asked Questions

What is the anticipated growth of the Ulcerated Necrobiosis Lipoidica Management Market until 2033?

FMI projects the global Ulcerated Necrobiosis Lipoidica Management Market to expand at 6.03% value CAGR by 2033.

What is the estimated market value of the Ulcerated Necrobiosis Lipoidica Management Market expected in 2033?

The global Ulcerated Necrobiosis Lipoidica Management Market is expected to garner a market value of USD 7.9 billion by 2033.

Which region is forecast to be the most lucrative for Ulcerated Necrobiosis Lipoidica Management Market growth?

FMI has projected North America to be one of the most profitable regions for Ulcerated Necrobiosis Lipoidica Management Market.

Which region is expected to grow fastest during the forecast period?

Asia Pacific is anticipated to grow fastest during the forecast period.

By treatment type, which segment is expected to dominate the market by 2033?

UVA1 Phototherapy is expected to dominate the market by treatment type during the forecast period

By end-user, which segment is most likely to lead Ulcerated Necrobiosis Lipoidica treatment industry?

Hospitals are projected to lead the market with maximum share by end of the forecast period

What was the market value of Ulcerated Necrobiosis Lipoidica in 2018?

The market value of Ulcerated Necrobiosis Lipoidica Management Market was worth USD 3.5 billion in 2018.

What is the expected market share of Ulcerated Necrobiosis Lipoidica in North America?

The market in North America is projected to account for 41% market share by end of the forecast period.

Table of Content
	1. Executive Summary | Ulcerated Necrobiosis Lipoidica Management Market
	2. Market Overview
	3. Market Background
	4. Global Market Analysis 2018 to 2022 and Forecast, 2023 to 2033
	5. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Treatment
		5.1. Skin Grafting
		5.2. Photodynamic Therapy
		5.3. UVA1 Phototherapy
		5.4. Topical Psoralen-UVA Therapy
		5.5. Drugs
			5.5.1. Antimalarial Agents
			5.5.2. Antitubercular Agents
			5.5.3. Immunosuppressive Agents
			5.5.4. Hemorrheologic Agents
			5.5.5. Fumaric Acid Esters
			5.5.6. Calcineurin Inhibitors
			5.5.7. Corticosteroids
	6. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By End User
		6.1. Hospitals
		6.2. Specialty Clinics
		6.3. Others
	7. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Region
		7.1. North America
		7.2. Latin America
		7.3. Europe
		7.4. Asia Pacific
		7.5. Middle East and Africa
	8. North America Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
	9. Latin America Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
	10. Europe Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
	11. Asia Pacific Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
	12. Middle East and Africa Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
	13. Key Countries Market Analysis
	14. Market Structure Analysis
	15. Competition Analysis
		15.1. Astellas Pharma
		15.2. Vibcare Pharma
		15.3. Pfizer
		15.4. Manus Aktteva Biopharma LLP
		15.5. Mylan Pharmaceuticals Inc.
		15.6. Upsher-Smith Laboratories
		15.7. Novartis
		15.8. Sanofi
		15.9. Merck
		15.10. GlaxoSmithKline
	16. Assumptions & Acronyms Used
	17. Research Methodology
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