The global sphingolipids market was valued at about USD 564.0 Million in 2021, with the global market estimated to surge ahead at a CAGR of 5.1% to reach an estimated valuation of around USD 991.8 Million by the end of 2032. Conventional lipid-based drug delivery systems (LBDDS) are driving the global sphingolipids market as of 2021, holding a 61.9% global market share.
Market Outlook:
| Data | Market Insight |
|---|---|
| Market Value 2021 | USD 564.0 Million |
| Estimated market Value 2022 | USD 601.3 Million |
| Estimated market Value 2032 | USD 991.8 Million |
| CAGR of 2022 to 2032 | 5.1% |
| Market share of Top 5 countries | 66.3% |
| Key Market players | Merck KGaA; CordenPharma International; Lipoid GmbH; LARODAN AB; Croda International Plc.; Biosynth; Santa Cruz Biotechnology, Inc.; Creative Enzymes; CD Bioparticles; Cayman Chemical Company; and Others (Biosolve BV and others) |
Sphingolipids are a subclass of lipids with sphingoid bases as their backbone, a group of aliphatic amino alcohols that also includes sphingosine. Sphingolipids have many biological activities and are abundant in the central nervous system (CNS). They take part in tissue formation, cell identification, and adhesion, and function as toxin receptors. They are crucial for a number of biological functions, including differentiation, apoptosis, and signaling.
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The sphingolipids market is expected to hold a market value of USD 564.0 Million by 2032. Overall, sphingolipids market sales account for approximately 2.8% revenue share in the global pharmaceutical lipids market, which was valued at around USD 4.4 Billion in 2021.
The global sphingolipids market recorded a CAGR of 4.7% in the historic years from 2012 to 2021.
Sphingolipids are thought of as essential excipients in the pharmaceutical as well as cosmetics industries for the production of numerous prescription drugs. They take on many different functions, including those of solubilizes, transfection agents, stabilisers, permeation enhancers, and others.
Throughout the anticipated years, the market is expected to be driven by the increasing use of semi-synthetic, synthetic, natural, or entirely man-made sphingolipids and monomers in the manufacturing of various pharmaceutical formulations.
In addition, an emerging factor driving the expansion of the worldwide sphingolipids market is enhanced drug delivery technology through prescription medications. The frequency of dispersion, level of emulsification, size of the particles, and other design elements will also contribute to the market's expansion sphingolipids market.
The manufacturing of liposomal drugs for the treatment of cancer, cardiovascular disorders, chronic illnesses, and excipients is being fuelled by the global need for pharmaceuticals. These drivers will cause the sphingolipids market to expand steadily over the forecast period.
Sphingolipids have been shown to be essential in preventing pulmonary leaks and lung injury during the past several years, and altering their routes may be a method for therapeutic interventions.
For instance, the WHO reports that dangerous and challenging-to-treat pneumonia is the most typical diagnosis among individuals with severe COVID-19 & cardiac illness. Acute respiratory distress syndrome (ARDS) is typically associated with patients who have an overactive inflammatory response.
In order to prevent the rapid clinical deterioration of individuals with COVID-19 and cardiovascular disorders, it may be necessary to take action on numerous different levels.
The aforementioned factors are expected to serve as probable market drivers for the global sphingolipids market and help the market to expand significantly in the forecast period.
Sales of pharmaceutical lipids are expected to be driven by rising demand for pharmaceutical sphingolipids, as a result of chronic diseases, the high prevalence of cancer, as well as a growing emphasis on physical well-being.
Sphingolipids appear to be strong contenders for use in the food, cosmetics, pharmaceutical, and healthcare industries. The potential of sphingolipid molecules will grow in the future as more and more new sources and structures are identified. The potential to use chemical techniques to change the structure of natural sphingolipids can also expand the range of applications for them.
Manufacturers can concentrate on creating products using natural sphingolipids, which can be extracted from biological samples and further modified chemically to produce sphingolipid compounds with novel features that are appealing to be used in cosmetic, pharmaceutical, and medical applications.
For instance, phenethyl isothiocyanate and 4-sphingosine can be coupled to have greater inhibitory activity against the proliferation of human leukaemia cells.
The abovementioned factors are capable of acting as lucrative opportunities for manufacturers operating in the sphingolipids market.
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Some adverse reactions, including peripheral neuropathy brought on by paclitaxel, may be dose-limiting, further lowering the efficacy of paclitaxel chemotherapy. Radiation and chemotherapy treatments can have serious effects on young female patients' ability to conceive if their ovarian failure occurs prematurely.
Sphingolipids have been found to contribute to the side effects of cancer treatments in recent years. Sphingolipids have been demonstrated to be dysregulated in cancer and have a significant role in both cell proliferation and death.
There are more rules to control the quality and effectiveness of medications as a result of the global pharmaceutical industry's expansion. When it comes to following a nation's legal standards for the drug development process, regulatory authorities and organisations are crucial.
The standards for producing lipid-based excipients are not currently defined by any established rules. However, despite the fact that many manufacturing facilities do not follow IPEC criteria, most manufacturers generally accept them.
The above-mentioned factors can challenge the market expansion of the global sphingolipids market.
The USA held the greatest share in the regional sphingolipids market with about 94.5% share at the end of the year 2021. The biggest market for sphingolipids is the USA This is because there are numerous manufacturers in this industry and sphingolipids are in great demand across a variety of end-use sectors.
As of 2021, Germany is leading the European market withholding about 32.5% of the regional market share with a valuation of around USD 49.7 Million. The market is primarily driven by the growing knowledge of the nutritional and functional value of sphingolipids. Synthetic sphingolipid synthesis for pharmaceutical uses increased as a result of the expanding demand for lipids, especially in Western Europe.
The market for sphingolipids is primarily driven by rising health consciousness and the resulting rise in demand for wholesome and secure food items. Consumers now place a greater emphasis on healthy eating, value quality over quantity, and choose to purchase fewer but higher-quality, more natural goods.
China has led the regional market with a massive share of about 68.6% and generated revenue of about USD113.6 Million at the end of 2021.
This is spurred on by a rise in sphingolipid demand due to their characteristics, sphingolipids, and their derivatives are highly bioactive substances with anti-cancer, bacteriostatic, and cholesterol-lowering effects. Sphingolipids are in high demand since Chinese consumers use them extensively in their everyday diet.
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By product, sphingomyelin has driven the global market with a decent amount of market share of about 29.0% in 2021 and is expected to grow at a CAGR of 5.5%. With anti-cancer, bacteriostatic, and cholesterol-lowering characteristics, sphingolipids and their derivatives, such as sphingomyelin, are extremely bioactive substances. Owing to such properties the market for sphingomyelin is expected to grow exponentially.
By source, synthetic sphingolipids are in demand, and as of 2021, synthetic sphingolipids accounted for USD 216.5 Million. By disrupting cell signalling, membrane trafficking, and the binding of infectious pathogens, synthetic sphingolipids offer potential as therapeutic candidates for treating a variety of disease conditions. Due to such benefits, the market is anticipated to propel in the future too.
By application, conventional lipid-based drug delivery systems (LBDDS) have driven the market by holding a majority of the market share of about 61.9% and achieved a valuation of USD 349.1 Million at the end of 2021.
By presenting the pharmaceutical composition in a solubilized condition, as opposed to conventional tablets or powder-filled capsules, LBDDS can improve bioavailability and eliminate dissolving rate-limited absorption. The homogeneity of dosage form content may also be enhanced for medications with high potencies.
By form, semi-solids have led the market by accounting for around USD 345.5 Million by the end of 2021. This dominance is a result of the advantage that local treatment of a variety of dermatological conditions is made possible by semi-solid dosage forms, such as topical application, with very few systemic side effects.
The probability of negative side effects is decreased when a high drug load is applied to the area where the medication is genuinely required. Topical drugs are easy for the patient to apply, and because of their nourishing qualities, semi-solid dosage forms are beneficial for a range of skin problems.
By end user, pharmaceutical companies have driven the global sphingolipids market by achieving a valuation of USD 200.2 Million by the end of 2021. Global and diverse pharmaceutical companies have emerged. Pharma manufacturers are dominating the market with increased outsourcing, innovative modalities, and creative patient outreach strategies.
Major manufacturers are concentrating on accelerating the process to boost sales of medications containing sphingolipids. In order to lower the expenses associated with medicine development and production, they are also utilizing technical innovations.
In the upcoming years, the market is anticipated to be driven by this. The main tactics used by manufacturers to boost product sales in different locations include strategic alliances, acquisitions, expansion, new launches, agreements, and research sponsorship.
Similarly, recent developments related to companies manufacturing sphingolipids, have been tracked by the team at Future Market Insights, which are available in the full report.
| Attribute | Details |
|---|---|
| Forecast Period | 2022 to 2032 |
| Historical Data Available for | 2012 to 2021 |
| Market Analysis | USD Million for Value |
| Key Regions Covered | North America, Latin America, Europe, East Asia, South Asia, Oceania, and Middle East & Africa (MEA). |
| Key Countries Covered | USA, Canada, Brazil, Mexico, Argentina, UK, Germany, Italy, Russia, Spain, France, BENELUX, Rest of Europe, Japan, China, South Korea, India, Thailand, Indonesia, Malaysia, Australia, New Zealand, Turkey, GCC, South Africa, North Africa and Rest of MEA. |
| Key Market Segments Covered | Product, Source, Form, Application, End User, and Region |
| Key Companies Profiled | Merck KGaA, CordenPharma International, Lipoid GmbH, LARODAN AB, Croda International Plc., Biosynth, Santa Cruz Biotechnology, Inc., Creative Enzymes, CD Bioparticles, Cayman Chemical Company, and Biosolve BV |
| Pricing | Available upon Request |
The global sphingolipids market is worth USD 564.0 Million at end of 2021.
The sphingolipids market is expected to reach USD 991.8 Million by end of 2032 at a CAGR of 5.1%.
Molecular and biological developments in sphingolipids providing promising health benefits and increasing sedentary lifestyles among people leading to an increase in the prevalence of cardiovascular diseases and cancer are some of the key factors that drive this market.
The North American region has the highest market share of about 27.6% in 2021 in the global sphingolipids market.
South Asia accounted for about 10.9% of the market share in 2021 in the global sphingolipids market.
The USA, China, Germany, and India are the top five countries, which are expected to drive demand in the sphingolipids market.
Merck KGaA, CordenPharma International, Lipoid GmbH, LARODAN AB, Croda International Plc., Biosynth, Santa Cruz Biotechnology, Inc., Creative Enzymes, CD Bioparticles, Cayman Chemical Company, and Biosolve BV are some of the key players in the sphingolipids industry.
From 2012 to 2021, the market for sphingolipids expanded at the rate of 4.7%.
China accounted for 68.6% of the market share at the end of 2021 in the East Asian market.
Germany displayed a market share of around 32.5% in 2021 in the European sphingolipids market
1. Executive Summary 2. Market Overview 3. Key Market Trends 4. Key Success Factors 5. Market Background 6. Global Demand (in Value or Size in US$ Million) Analysis 2012 to 2021 and Forecast, 2022 to 2032 7. Global Market Analysis 2012 to 2021 and Forecast 2022 to 2032, By Product 7.1. Ceramide 7.2. Sphingomyelin 7.3. Glucosylceramide (GlcCer) 7.4. Lactosylceramide (LacCer) 7.5. Ganglioside GM3 7.6. Other 8. Global Market Analysis 2012 to 2021 and Forecast 2022 to 2032, By Source 8.1. Synthetic 8.2. Semi-synthetic 8.3. Natural 9. Global Market Analysis 2012 to 2021 and Forecast 2022 to 2032, By Application 9.1. Conventional Lipid-based Drug Delivery Systems (LBDDS) 9.2. Self-Emulsifying Drug Delivery Systems (SEDDS) 9.3. Self-Microemulsifying Drug Delivery Systems (SMEDDS) 9.4. Liposomes 9.5. Solid Lipid Nanoparticles 9.6. Nanostructured Lipid Carriers 9.7. Others 10. Global Market Analysis 2012 to 2021 and Forecast 2022 to 2032, By Form 10.1. Liquid 10.2. Semi-solid 10.3. Solid 11. Global Market Analysis 2012 to 2021 and Forecast 2022 to 2032, By End User 11.1. Pharmaceutical Companies 11.2. Biopharmaceutical Companies 11.3. Academics and Research Institutes 11.4. Others 12. Global Market Analysis 2012 to 2021 and Forecast 2022 to 2032, By Region 12.1. North America 12.2. Latin America 12.3. Europe 12.4. East Asia 12.5. South Asia 12.6. Oceania 12.7. Middle East and Africa (MEA) 13. North America Market Analysis 2012 to 2021 and Forecast 2022 to 2032 14. Latin America Market Analysis 2012 to 2021 and Forecast 2022 to 2032 15. Europe Market Analysis 2012 to 2021 and Forecast 2022 to 2032 16. East Asia Market Analysis 2012 to 2021 and Forecast 2022 to 2032 17. South Asia Market Analysis 2012 to 2021 and Forecast 2022 to 2032 18. Oceania Market Analysis 2012 to 2021 and Forecast 2022 to 2032 19. Middle East and Africa (MEA) Market Analysis 2012 to 2021 and Forecast 2022 to 2032 20. Market Structure Analysis 21. Competition Analysis 21.1. Merck KGaA 21.2. CordenPharma International 21.3. Lipoid GmbH 21.4. LARODAN AB 21.5. Croda International Plc. 21.6. Biosynth 21.7. Santa Cruz Biotechnology, Inc. 21.8. Creative Enzymes 21.9. CD Bioparticles 21.10. Cayman Chemical Company 21.11. Biosolve BV 22. Assumptions and Acronyms Used 23. Research Methodology
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Sphingolipids Market
