The global protein purification and isolation market is expected to reach a market valuation of US$ 9.03 billion by 2023, accelerating with a moderate CAGR of 10.6% from 2023 to 2033. The market is anticipated to surpass a valuation of US$ 24.76 billion by 2033.
Increased governmental and private funding for protein research, growing interest in structure-based medication design, and technological innovations, such as single-use technologies and automated purification instruments, all contribute to the growth of the global protein purification & isolation market.
Governments are increasing their support for the pharmaceutical and biotechnology industries by investing in R&D and launching initiatives to promote the protein purification and isolation sectors' growth and development. Plus, they've thrown in some extras like tax breaks, free money, and laws that are easy on investors.
The pharmaceutical sector in the protein purification and isolation market has made significant expenditures in the creation of biomarker-specific compounds, making it a profitable demand for protein purification and isolation solutions. Preclinical drug research relies heavily on the accurate separation of proteins using a high concentration of pure substrate. As a result of these elements, the demand for protein purification and isolation is expected to grow.
| Attributes | Value |
|---|---|
| Protein Purification and Isolation Market Size (2023) | 10.6% |
| Protein Purification and Isolation Market Projected Size (2033) | US$ 24.76 billion |
| Protein Purification and Isolation Market Value CAGR (2023) | US$ 9.03 billion |
The growth of the protein purification and isolation market is hindered, however, by factors such as poor acceptance rates for instruments, the difficulty of maintaining purifying kits that fulfill all demands, and the high cost of tools.
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Drivers
R&D spending on drug discovery and development has increased.
The protein purification and isolation market has benefited from the increasing focus on medication research and development. Protein analysis is a crucial step in the discovery of new drug and biotech product candidates. Thus, the acceptance of novel medication therapy has provided a major boost to the motivation to discover new and sophisticated pharmaceuticals. As a result, the demand for protein purification and isolation is expected to benefit from the subsequent rise in R&D and associated spending.
Developments in technology
Ongoing technological advancements propel protein purification and isolation solutions even further. Magnetic and protein beads and ligand tagging systems are replacing traditional methods such as agarose beads and other resins. Additionally, the increasing use of automated analyzers is expected to drive demand for protein purification and isolation.
Restraints
High tool prices, a lack of universally applicable purification kits, and a decrease in the adoption rate of new instruments impede the development of protein purification and isolation. Untapped growth areas and protein therapeutics are also helping develop protein purification and isolation market trends.
Expanding economies
Protein purification and isolation market growth opportunities are anticipated in the Asia-Pacific region due to its increasing focus on protein analysis-based technologies for drug discovery, its expanding R&D initiatives to develop novel proteomic and genomic techniques, its diverse healthcare markets, and its improving research infrastructure.
For instance, Purolite and PharmNXT Biotech formed a strategic alliance in May 2021 so that Purolite could provide PharmNXT Biotech's Praesto mAb chromatographic resin platform to South Korea and Singapore markets.
Lack of Qualified Individuals
Sample preparation plays a crucial role in protein purification and isolation by separating the analyte of interest and removing any interferences. Users incur additional direct and indirect costs due to a lack of expertise in selecting the best technology and preparing samples.
Principal Consultant
More than 35% of total sales of protein purification and isolation came from universities and other academic and research establishments. Demand for protein purification and isolation solutions is rising due to increased research into structural and functional proteomics, in-depth kinetic analysis, and protein-protein interaction at academic institutions. Protein purification and isolation services are used by a wide variety of industries, including pharmaceutical and biotech firms, contract research organizations (CROs), and universities and hospitals.
Over 30% of all protein purification and isolation sales in 2022 came from research on protein-protein interactions, which is expected to expand significantly over the next few years. The increasing number of research based on structural proteins and the widespread use of the procedures used to derive these proteins are driving the expansion of the protein purification and isolation market.
When it came to the percentage of total sales of protein purification and isolation, North America took 34.4% in 2023. Protein purification and isolation equipment sales are bolstered by the area's robust funding for life science research, well-established research infrastructure, and presence of other key elements.
The rise in biopharmaceutical medication development during the forecast period is also expected to boost the regional protein purification and isolation market.
Improvements in application areas such as protein-protein interaction investigations, target detection, drug screening, protein treatments, biomarker identification, sickness tracking, and diagnostic testing drive demand for technologically advanced protein isolation methods in North America.
It is anticipated that the Asia Pacific protein purification and isolation market region would experience the most rapid expansion throughout the projection period. The demand for protein purification and isolation solutions is expected to be driven in this area by initiatives done by the governments of developing nations such as India and China to develop healthcare infrastructure. In addition, these governments are contributing money to the research and development of innovative strategies for purification and isolation.
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Protein purification and isolation market participants are attempting to increase their foothold by implementing tactics like new product launches, geographic expansion, mergers, acquisitions, and partnerships. For instance, in September 2021, GE Healthcare Life Sciences agreed to purchase BK Medical from Altaris Capital Partners, LLC, for USD 1.45 billion in cash. The deal was announced in December 2021.
In March of 2022, Thermo Fisher Scientific and Symphogen announced they would continue working together to supply biopharmaceutical R&D laboratories with platform workflows for quality monitoring and simplified characterization of complex therapeutic proteins. Thermo Fisher Scientific's dominance in the protein purification and separation market is expected to be preserved thanks to this.
The leading protein purification and isolation market companies are investing heavily in R&D to create innovative products that would likely boost the industry.
More than 25 companies cater to the developed and extremely diverse protein purification and separation sector. As a result of recent developments in R&D, the demand for protein purification and isolation is anticipated to expand throughout the forecast period.
New entrants in the protein purification and isolation market are using various tactics to enhance their market share, such as developing new products, expanding into new regions, merging with existing businesses, and forming partnerships.
The market is valued at US$ 9.03 billion in 2023.
Protein-protein interaction studies is the key application segment in the market.
The market shall reach US$ 24.76 billion in 2033.
North America is the leading region in the market.
Merck KGaA, GE Healthcare Life Sciences, and Qiagen NV. are key market players.
1. Executive Summary
1.1. Global Market Outlook
1.2. Demand-side Trends
1.3. Supply-side Trends
1.4. Technology Roadmap Analysis
1.5. Analysis and Recommendations
2. Market Overview
2.1. Market Coverage / Taxonomy
2.2. Market Definition / Scope / Limitations
3. Market Background
3.1. Market Dynamics
3.1.1. Drivers
3.1.2. Restraints
3.1.3. Opportunity
3.1.4. Trends
3.2. Scenario Forecast
3.2.1. Demand in Optimistic Scenario
3.2.2. Demand in Likely Scenario
3.2.3. Demand in Conservative Scenario
3.3. Opportunity Map Analysis
3.4. Investment Feasibility Matrix
3.5. PESTLE and Porter’s Analysis
3.6. Regulatory Landscape
3.6.1. By Key Regions
3.6.2. By Key Countries
3.7. Regional Parent Market Outlook
4. Global Market Analysis 2018 to 2022 and Forecast, 2023 to 2033
4.1. Historical Market Size Value (US$ Million) Analysis, 2018 to 2022
4.2. Current and Future Market Size Value (US$ Million) Projections, 2023 to 2033
4.2.1. Y-o-Y Growth Trend Analysis
4.2.2. Absolute $ Opportunity Analysis
5. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Product
5.1. Introduction / Key Findings
5.2. Historical Market Size Value (US$ Million) Analysis By Product, 2018 to 2022
5.3. Current and Future Market Size Value (US$ Million) Analysis and Forecast By Product, 2023 to 2033
5.3.1. Instruments
5.3.2. Consumables
5.3.2.1. Kits
5.3.2.2. Reagents
5.3.2.3. Columns
5.3.2.4. Magnetic Beads
5.3.2.5. Resins
5.3.2.6. Others
5.4. Y-o-Y Growth Trend Analysis By Product, 2018 to 2022
5.5. Absolute $ Opportunity Analysis By Product, 2023 to 2033
6. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Technology
6.1. Introduction / Key Findings
6.2. Historical Market Size Value (US$ Million) Analysis By Technology, 2018 to 2022
6.3. Current and Future Market Size Value (US$ Million) Analysis and Forecast By Technology, 2023 to 2033
6.3.1. Ultrafiltration
6.3.2. Precipitation
6.3.3. Chromatography
6.3.3.1. Ion Exchange Chromatography
6.3.3.2. Affinity Chromatography
6.3.3.3. Reversed-Phase Chromatography
6.3.3.4. Size Exclusion Chromatography
6.3.3.5. Hydrophobic Interaction Chromatography
6.3.4. Electrophoresis
6.3.4.1. Gel Electrophoresis
6.3.4.2. Isoelectric Focusing
6.3.4.3. Capillary Electrophoresis
6.3.5. Western Blotting
6.3.6. Others
6.4. Y-o-Y Growth Trend Analysis By Technology, 2018 to 2022
6.5. Absolute $ Opportunity Analysis By Technology, 2023 to 2033
7. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Application
7.1. Introduction / Key Findings
7.2. Historical Market Size Value (US$ Million) Analysis By Application, 2018 to 2022
7.3. Current and Future Market Size Value (US$ Million) Analysis and Forecast By Application, 2023 to 2033
7.3.1. Drug Screening
7.3.2. Biomarker Discovery
7.3.3. Protein-protein Interaction Studies
7.3.4. Diagnostics
7.4. Y-o-Y Growth Trend Analysis By Application, 2018 to 2022
7.5. Absolute $ Opportunity Analysis By Application, 2023 to 2033
8. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By End Use
8.1. Introduction / Key Findings
8.2. Historical Market Size Value (US$ Million) Analysis By End Use, 2018 to 2022
8.3. Current and Future Market Size Value (US$ Million) Analysis and Forecast By End Use, 2023 to 2033
8.3.1. Academic and Research Institutes
8.3.2. Hospitals
8.3.3. Pharmaceutical and Biotechnological Companies
8.3.4. CROs
8.4. Y-o-Y Growth Trend Analysis By End Use, 2018 to 2022
8.5. Absolute $ Opportunity Analysis By End Use, 2023 to 2033
9. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Region
9.1. Introduction
9.2. Historical Market Size Value (US$ Million) Analysis By Region, 2018 to 2022
9.3. Current Market Size Value (US$ Million) Analysis and Forecast By Region, 2023 to 2033
9.3.1. North America
9.3.2. Latin America
9.3.3. Western Europe
9.3.4. Eastern Europe
9.3.5. South Asia and Pacific
9.3.6. East Asia
9.3.7. Middle East and Africa
9.4. Market Attractiveness Analysis By Region
10. North America Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
10.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022
10.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033
10.2.1. By Country
10.2.1.1. USA
10.2.1.2. Canada
10.2.2. By Product
10.2.3. By Technology
10.2.4. By Application
10.2.5. By End Use
10.3. Market Attractiveness Analysis
10.3.1. By Country
10.3.2. By Product
10.3.3. By Technology
10.3.4. By Application
10.3.5. By End Use
10.4. Key Takeaways
11. Latin America Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
11.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022
11.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033
11.2.1. By Country
11.2.1.1. Brazil
11.2.1.2. Mexico
11.2.1.3. Rest of Latin America
11.2.2. By Product
11.2.3. By Technology
11.2.4. By Application
11.2.5. By End Use
11.3. Market Attractiveness Analysis
11.3.1. By Country
11.3.2. By Product
11.3.3. By Technology
11.3.4. By Application
11.3.5. By End Use
11.4. Key Takeaways
12. Western Europe Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
12.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022
12.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033
12.2.1. By Country
12.2.1.1. Germany
12.2.1.2. UK
12.2.1.3. France
12.2.1.4. Spain
12.2.1.5. Italy
12.2.1.6. Rest of Western Europe
12.2.2. By Product
12.2.3. By Technology
12.2.4. By Application
12.2.5. By End Use
12.3. Market Attractiveness Analysis
12.3.1. By Country
12.3.2. By Product
12.3.3. By Technology
12.3.4. By Application
12.3.5. By End Use
12.4. Key Takeaways
13. Eastern Europe Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
13.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022
13.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033
13.2.1. By Country
13.2.1.1. Poland
13.2.1.2. Russia
13.2.1.3. Czech Republic
13.2.1.4. Romania
13.2.1.5. Rest of Eastern Europe
13.2.2. By Product
13.2.3. By Technology
13.2.4. By Application
13.2.5. By End Use
13.3. Market Attractiveness Analysis
13.3.1. By Country
13.3.2. By Product
13.3.3. By Technology
13.3.4. By Application
13.3.5. By End Use
13.4. Key Takeaways
14. South Asia and Pacific Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
14.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022
14.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033
14.2.1. By Country
14.2.1.1. India
14.2.1.2. Bangladesh
14.2.1.3. Australia
14.2.1.4. New Zealand
14.2.1.5. Rest of South Asia and Pacific
14.2.2. By Product
14.2.3. By Technology
14.2.4. By Application
14.2.5. By End Use
14.3. Market Attractiveness Analysis
14.3.1. By Country
14.3.2. By Product
14.3.3. By Technology
14.3.4. By Application
14.3.5. By End Use
14.4. Key Takeaways
15. East Asia Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
15.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022
15.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033
15.2.1. By Country
15.2.1.1. China
15.2.1.2. Japan
15.2.1.3. South Korea
15.2.2. By Product
15.2.3. By Technology
15.2.4. By Application
15.2.5. By End Use
15.3. Market Attractiveness Analysis
15.3.1. By Country
15.3.2. By Product
15.3.3. By Technology
15.3.4. By Application
15.3.5. By End Use
15.4. Key Takeaways
16. Middle East and Africa Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
16.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022
16.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033
16.2.1. By Country
16.2.1.1. GCC Countries
16.2.1.2. South Africa
16.2.1.3. Israel
16.2.1.4. Rest of MEA
16.2.2. By Product
16.2.3. By Technology
16.2.4. By Application
16.2.5. By End Use
16.3. Market Attractiveness Analysis
16.3.1. By Country
16.3.2. By Product
16.3.3. By Technology
16.3.4. By Application
16.3.5. By End Use
16.4. Key Takeaways
17. Key Countries Market Analysis
17.1. USA
17.1.1. Pricing Analysis
17.1.2. Market Share Analysis, 2022
17.1.2.1. By Product
17.1.2.2. By Technology
17.1.2.3. By Application
17.1.2.4. By End Use
17.2. Canada
17.2.1. Pricing Analysis
17.2.2. Market Share Analysis, 2022
17.2.2.1. By Product
17.2.2.2. By Technology
17.2.2.3. By Application
17.2.2.4. By End Use
17.3. Brazil
17.3.1. Pricing Analysis
17.3.2. Market Share Analysis, 2022
17.3.2.1. By Product
17.3.2.2. By Technology
17.3.2.3. By Application
17.3.2.4. By End Use
17.4. Mexico
17.4.1. Pricing Analysis
17.4.2. Market Share Analysis, 2022
17.4.2.1. By Product
17.4.2.2. By Technology
17.4.2.3. By Application
17.4.2.4. By End Use
17.5. Germany
17.5.1. Pricing Analysis
17.5.2. Market Share Analysis, 2022
17.5.2.1. By Product
17.5.2.2. By Technology
17.5.2.3. By Application
17.5.2.4. By End Use
17.6. UK
17.6.1. Pricing Analysis
17.6.2. Market Share Analysis, 2022
17.6.2.1. By Product
17.6.2.2. By Technology
17.6.2.3. By Application
17.6.2.4. By End Use
17.7. France
17.7.1. Pricing Analysis
17.7.2. Market Share Analysis, 2022
17.7.2.1. By Product
17.7.2.2. By Technology
17.7.2.3. By Application
17.7.2.4. By End Use
17.8. Spain
17.8.1. Pricing Analysis
17.8.2. Market Share Analysis, 2022
17.8.2.1. By Product
17.8.2.2. By Technology
17.8.2.3. By Application
17.8.2.4. By End Use
17.9. Italy
17.9.1. Pricing Analysis
17.9.2. Market Share Analysis, 2022
17.9.2.1. By Product
17.9.2.2. By Technology
17.9.2.3. By Application
17.9.2.4. By End Use
17.10. Poland
17.10.1. Pricing Analysis
17.10.2. Market Share Analysis, 2022
17.10.2.1. By Product
17.10.2.2. By Technology
17.10.2.3. By Application
17.10.2.4. By End Use
17.11. Russia
17.11.1. Pricing Analysis
17.11.2. Market Share Analysis, 2022
17.11.2.1. By Product
17.11.2.2. By Technology
17.11.2.3. By Application
17.11.2.4. By End Use
17.12. Czech Republic
17.12.1. Pricing Analysis
17.12.2. Market Share Analysis, 2022
17.12.2.1. By Product
17.12.2.2. By Technology
17.12.2.3. By Application
17.12.2.4. By End Use
17.13. Romania
17.13.1. Pricing Analysis
17.13.2. Market Share Analysis, 2022
17.13.2.1. By Product
17.13.2.2. By Technology
17.13.2.3. By Application
17.13.2.4. By End Use
17.14. India
17.14.1. Pricing Analysis
17.14.2. Market Share Analysis, 2022
17.14.2.1. By Product
17.14.2.2. By Technology
17.14.2.3. By Application
17.14.2.4. By End Use
17.15. Bangladesh
17.15.1. Pricing Analysis
17.15.2. Market Share Analysis, 2022
17.15.2.1. By Product
17.15.2.2. By Technology
17.15.2.3. By Application
17.15.2.4. By End Use
17.16. Australia
17.16.1. Pricing Analysis
17.16.2. Market Share Analysis, 2022
17.16.2.1. By Product
17.16.2.2. By Technology
17.16.2.3. By Application
17.16.2.4. By End Use
17.17. New Zealand
17.17.1. Pricing Analysis
17.17.2. Market Share Analysis, 2022
17.17.2.1. By Product
17.17.2.2. By Technology
17.17.2.3. By Application
17.17.2.4. By End Use
17.18. China
17.18.1. Pricing Analysis
17.18.2. Market Share Analysis, 2022
17.18.2.1. By Product
17.18.2.2. By Technology
17.18.2.3. By Application
17.18.2.4. By End Use
17.19. Japan
17.19.1. Pricing Analysis
17.19.2. Market Share Analysis, 2022
17.19.2.1. By Product
17.19.2.2. By Technology
17.19.2.3. By Application
17.19.2.4. By End Use
17.20. South Korea
17.20.1. Pricing Analysis
17.20.2. Market Share Analysis, 2022
17.20.2.1. By Product
17.20.2.2. By Technology
17.20.2.3. By Application
17.20.2.4. By End Use
17.21. GCC Countries
17.21.1. Pricing Analysis
17.21.2. Market Share Analysis, 2022
17.21.2.1. By Product
17.21.2.2. By Technology
17.21.2.3. By Application
17.21.2.4. By End Use
17.22. South Africa
17.22.1. Pricing Analysis
17.22.2. Market Share Analysis, 2022
17.22.2.1. By Product
17.22.2.2. By Technology
17.22.2.3. By Application
17.22.2.4. By End Use
17.23. Israel
17.23.1. Pricing Analysis
17.23.2. Market Share Analysis, 2022
17.23.2.1. By Product
17.23.2.2. By Technology
17.23.2.3. By Application
17.23.2.4. By End Use
18. Market Structure Analysis
18.1. Competition Dashboard
18.2. Competition Benchmarking
18.3. Market Share Analysis of Top Players
18.3.1. By Regional
18.3.2. By Product
18.3.3. By Technology
18.3.4. By Application
18.3.5. By End Use
19. Competition Analysis
19.1. Competition Deep Dive
19.1.1. Merck KGaA
19.1.1.1. Overview
19.1.1.2. Product Portfolio
19.1.1.3. Profitability by Market Segments
19.1.1.4. Sales Footprint
19.1.1.5. Strategy Overview
19.1.1.5.1. Marketing Strategy
19.1.2. Thermo Fischer Scientific, Inc.
19.1.2.1. Overview
19.1.2.2. Product Portfolio
19.1.2.3. Profitability by Market Segments
19.1.2.4. Sales Footprint
19.1.2.5. Strategy Overview
19.1.2.5.1. Marketing Strategy
19.1.3. GE Healthcare Life Sciences
19.1.3.1. Overview
19.1.3.2. Product Portfolio
19.1.3.3. Profitability by Market Segments
19.1.3.4. Sales Footprint
19.1.3.5. Strategy Overview
19.1.3.5.1. Marketing Strategy
19.1.4. Qiagen N.V.
19.1.4.1. Overview
19.1.4.2. Product Portfolio
19.1.4.3. Profitability by Market Segments
19.1.4.4. Sales Footprint
19.1.4.5. Strategy Overview
19.1.4.5.1. Marketing Strategy
19.1.5. Sigma-Aldrich Corporation
19.1.5.1. Overview
19.1.5.2. Product Portfolio
19.1.5.3. Profitability by Market Segments
19.1.5.4. Sales Footprint
19.1.5.5. Strategy Overview
19.1.5.5.1. Marketing Strategy
19.1.6. Agilent Technologies
19.1.6.1. Overview
19.1.6.2. Product Portfolio
19.1.6.3. Profitability by Market Segments
19.1.6.4. Sales Footprint
19.1.6.5. Strategy Overview
19.1.6.5.1. Marketing Strategy
19.1.7. Bio-Rad Laboratories, Inc.
19.1.7.1. Overview
19.1.7.2. Product Portfolio
19.1.7.3. Profitability by Market Segments
19.1.7.4. Sales Footprint
19.1.7.5. Strategy Overview
19.1.7.5.1. Marketing Strategy
19.1.8. Promega Corporation
19.1.8.1. Overview
19.1.8.2. Product Portfolio
19.1.8.3. Profitability by Market Segments
19.1.8.4. Sales Footprint
19.1.8.5. Strategy Overview
19.1.8.5.1. Marketing Strategy
19.1.9. Norgen Biotek Corp.
19.1.9.1. Overview
19.1.9.2. Product Portfolio
19.1.9.3. Profitability by Market Segments
19.1.9.4. Sales Footprint
19.1.9.5. Strategy Overview
19.1.9.5.1. Marketing Strategy
19.1.10. Abcam plc
19.1.10.1. Overview
19.1.10.2. Product Portfolio
19.1.10.3. Profitability by Market Segments
19.1.10.4. Sales Footprint
19.1.10.5. Strategy Overview
19.1.10.5.1. Marketing Strategy
20. Assumptions & Acronyms Used
21. Research Methodology
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Protein Purification and Isolation Market
