Postoperative Pain Market Outlook (2023 to 2033)

The global postoperative pain market size is estimated to be valued at USD 38.43 billion in 2023 and is projected to surpass a valuation of USD 63.8 billion by 2033. The adoption of postoperative pain drugs is likely to rise at a CAGR of 5.2% during the forecast period.

Some major factors propelling the postoperative pain industry growth include:

  • The market for postoperative pain is likely to expand due to the increased demand for pain management drugs and equipment.
  • Worldwide, the number of cancer patients having surgery is rising which is driving the market expansion.
  • Due to the sluggish healing processes associated with aging and medical patients' procedures, postoperative pain management is required.
  • Demand for postoperative pain treatment is anticipated to be driven by an increase in the number of traffic accidents, relative trauma injuries, and area unit needs for pain management following surgeries.
  • Postoperative pain management, however, can help with severe pain and soreness.

These factors are propelling the major players to increase their output, which is likely to ultimately result in positive market growth for postoperative pain.

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Adoption of Postoperative Pain Therapeutics Likely to be Fueled by High Incidence and Severity of Postoperative Pain

According to health experts, surgery is linked to long-lasting chronic postoperative pain that typically lasts between three and six months. The demand for postoperative pain is anticipated to rise as phantom pain is one of the frequent postoperative disorders that follows breast surgery, a cesarean section, a thoracotomy, limb amputation, or inguinal hernia repair. Numerous studies carried out in nations with highly established healthcare systems have shown that between one-third and fifty percent of patients do not have adequate postoperative pain management.

Introduction of Promising Drugs, and High Adoption Rate of Pain Management in Developed as well as Emerging Countries

The global market for postoperative pain treatments is predicted to experience growth over the forecast period due to an increase in surgical procedures and the intensity of postoperative pain. The global postoperative pain treatment market is anticipated to grow as a result of the development of numerous novel medications. Wide safety margins and advantageous characteristics are being used in the development of new medications.

The importance of non-opioid adjuncts and alternatives has increased for postoperative pain management. Examples of medications that have been popular in the postoperative pain market include intravenous (IV) acetaminophen, non-steroidal anti-inflammatory medicines (NSAIDs), magnesium, ketamine, dexmedetomidine, and liposomal bupivacaine. As a result, postoperative pain therapies now predominate in both emerging and developed markets due to innovative drugs, rising demand, better access, and improved pain management.

Attribute Details
Postoperative Pain Market Size (2023) USD 38.43 billion
Postoperative Pain Projected Market Value (2033) USD 63.8 billion
Global Postoperative Pain CAGR (2023 to 2033) 5.2%
Market Share of Top 5 Countries 65%
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2018 to 2022 Postoperative Pain Market Outlook in Comparison to 2023 to 2033 Forecast

Historically, the demand for postoperative pain drugs increased at a CAGR of 4.7% from 2018 to 2022. The market for postoperative pain was worth USD 30.4 billion in 2018, the market surpassed USD 36.53 billion by 2022. The demand for postoperative pain treatment is anticipated to increase in the future due to an increase in the number of traffic accidents, relative trauma injuries, and relative trauma injuries.

Attribute Valuation
2025 USD 42.53 billion
2028 USD 49.52 billion
2032 USD 60.65 billion

The market is anticipated to grow at a CAGR of 5.2% from 2023 to 2033, surpassing USD 63.8 billion by 2033.

  • Short Term (2022 to 2025): The demand for postoperative pain treatment techniques is increasing due to factors such as the prevalence of chronic disease, the increase in surgical procedures, the demand for novel non-opioid analgesics in postoperative pain therapy, and raising awareness of palliative care.
  • Medium Term (2025 to 2028): The excessive consumption of painkillers is mostly caused by the increasing number of surgeries performed around the world. Similar to how the prevalence of cancer therapy-related pain is rising, the market is projected to grow due to an aging and growing pediatric population having various sorts of surgeries.
  • Long Term (2028 to 2032): Postoperative discomfort can assist manage severe pain and soreness. Due to these factors, the major manufacturers are projected to boost their production, which will ultimately result in favorable growth for the postoperative pain market.

Country-wise Insights

United States to Witness High Growth in the Postoperative Pain Industry

According to projections, the USA is likely to control 87.9% of the market for postoperative pain in North America by 2022. The adoption of opioid treatment is anticipated to lessen the opioid epidemic's rising prevalence in North America, particularly in the United States. For instance, more than 200 million opioid medications were prescribed and given to patients in the United States in 2018.

Furthermore, it is anticipated that the usage of postoperative pain medications would rise in this region due to the strong drug pipeline with effective medications up for FDA clearance. Patients' attitudes have improved in the United States as a result of better compliance with pain treatment suggestions. The country's demand for postoperative pain management pharmaceuticals is probably going to rise as a result of these figures, which will help the industry grow.

Several industry participants are putting strategic plans into action, which is helping the market expand. For instance, Allay Therapeutics, a clinical-stage biotechnology company that has been at the forefront of developing ultra-sustained analgesic products to revolutionize postsurgical pain management and recovery, released the first-ever clinical data demonstrating non-opioid pain relief lasting two weeks after a single administration in May 2021.

Germany to Lead European Postoperative Pain

In 2022, Germany is anticipated to represent 26.9% of the market for postoperative pain in Europe. The market has grown due to the increasing prevalence and severity of postoperative pain, the launch of promising medications, an increase in surgical operations, and a high rate of pain procedures in developed nations like Germany.

Demand for postoperative pain medications is rising across Germany as opioid maintenance therapy (OMT) for treating opioid dependence (OD) becomes more widely accepted.

South Korea's Postoperative Pain Treatment Demand is Being Driven by a High Number of Surgeries

Due to the country's rising surgical rate, the postoperative pain market in South Korea is anticipated to grow at a 6.3% CAGR during the forecast period. Many manufacturers of painkillers are forming partnerships, and distribution agreements, and introducing postoperative painkillers in Korea. To increase their position in the worldwide market, major market players are concentrating on various business methods, such as obtaining product approval from regulatory bodies. On May 1, 2018, Grunenthal and Mundipharma struck a distribution and license deal, enabling Mundipharma to market and sell Grunenthal's Tramal (tramadol).

Japan Postoperative Pain Industry to Witness Growth Limiting and Factors

In Japan, opioids are usually prescribed for postoperative pain, but due to an increase in opioid use for non-medical reasons, governing bodies are pressuring doctors to prescribe non-opioid medications, which presents an opportunity for businesses to launch novel non-opioid medications. However, rising concerns about the opioid epidemic in the region and the rising burden of pain on providers of reimbursement are projected to limit the market's ability to grow to some extent.

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Category-wise Insights

Which Class of Drugs Has the Most Influence in the Postoperative Pain Industry?

By drug class, the opioids segment is predicted to grow at a 4% CAGR throughout the projection period to represent a significant proportion of 61.3% in 2022.

Adults who experience moderate to severe post-operative pain are typically treated with opioids, according to the NIH. As a result, over the past ten years, opioid use has increased. Opioid medications are recognized to be useful for treating postoperative pain and have demonstrated the capacity to support patients in accomplishing their clinical goals based on research studies and current trials.

Which Route of Administration Holds the Dominance in the Market?

High Demand for Oral Postoperative Pain Procedures

Oral postoperative pain is anticipated to hold 37.8% of the market in 2022 in terms of route of administration. For patients, especially the elderly, the oral route of administration is more convenient and widely accepted, which contributes to a bigger market share in the postoperative pain market. The high share of the market is ascribed to the segment's simplicity and patients' preference for oral drug administration.

What are the Players in the Postoperative Pain Industry Doing?

Leading providers of postoperative pain medications are collaborating and acquiring other pharmaceutical firms as their primary approach for the creation of new product lines of pain medications. The demand for painkiller pharmaceuticals is increasing as key stakeholders put more emphasis on the creation of abuse-deterrent opioid drugs and the launch of extended-release non-opioid drugs for post-surgery pain. Similar to this, greater non-narcotic drug discovery and commercialization as well as growing awareness of post-surgery pain management are supporting market expansion.

The market is anticipated to expand as a result of rising acute disease prevalence and an increase in the elderly population in emerging economies. Manufacturers of painkilling drugs should expect great opportunities as patient awareness of procedures and operations grows and as research into pain management expands. Market expansion is anticipated to expand as government efforts to encourage improved postoperative pain management increase.

Key Players in the Postoperative Pain Industry

  • Novartis AG
  • Allergan plc
  • Teva Pharmaceutical Industries Ltd.
  • Mylan N.V
  • Pfizer Inc.
  • Purdue Pharma L.P
  • Janssen Pharmaceuticals, Inc.
  • Endo International plc
  • Pacira Pharmaceuticals Inc.
  • Egalet Corporation
  • GlaxoSmithKline Plc.

Recent Developments in the Postoperative Pain Industry:

  • Zyla Life Sciences purchased Assertio Therapeutics, Inc. in May 2020. Due to this, a developing commercial pharmaceutical business was able to expand its line of neurology, inflammation, and pain medications.
  • The commercialization of ZYNRELEF (bupivacaine and meloxicam extended-release solution) for instillation into the surgical wound for postoperative analgesia following bunionectomy, open inguinal herniorrhaphy, and total knee arthroplasty surgical procedures was announced by Health Canada in March 2022, according to Heron Therapeutics, Inc.
  • The perioperative long-acting analgesic medication CPL-01 underwent a Phase IIb study in March 2022, and Cali Biosciences Co., Ltd., a biopharmaceutical firm focused on the discovery and development of novel pharmaceuticals, announced positive results.

Postoperative Pain Market Report Scope

Attribute Details
Forecast Period 2023 to 2033
Historical Data Available for 2018 to 2022
Market Analysis USD billion for Value
Key Countries Covered The USA, Canada, Germany, The United Kingdom, France, Italy, Spain, BENELUX, Russia, China, Japan, South Korea, India, Thailand, Malaysia, Indonesia, Australia, New Zealand, GCC Countries, Turkey, South Africa
Key Market Segments Covered By Drug Class, By Route of Administration, By Distribution Channel, By Region
Key Companies Profiled Novartis AG; Allergan plc; Teva Pharmaceutical Industries Ltd.; Mylan N.V.; Pfizer Inc.; Purdue Pharma L.P; Janssen Pharmaceuticals, Inc.; Endo International plc.; Pacira Pharmaceuticals Inc.; Egalet Corporation; GlaxoSmithKline Plc.
Report Coverage Market Forecast, Competition Intelligence, DROT Analysis, Market Dynamics and Challenges, Strategic Growth Initiatives
Customization & Pricing Available upon Request

Postoperative Pain Industry Survey by Category

By Drug Class:

  • Opioids
  • NSAIDs
  • Local Anesthetic
  • Acetaminophen

By Route of Administration:

  • Injectable
  • Oral
  • Topical
  • Transdermal
  • Others

By Distribution Channel:

  • Hospital Pharmacies
  • Retail Pharmacies
  • Drug Stores
  • Clinics
  • Others

By Region:

  • North America
  • Latin America
  • Europe
  • East Asia
  • South Asia
  • Oceania
  • Middle East & Africa

Frequently Asked Questions

What is the Current Postoperative Pain Market Size?

The postoperative pain market size is anticipated to be USD 38.43 billion in 2023.

How Big is the Postoperative Pain Market?

The postoperative pain market size is assessed to be USD 63.8 billion in 2033.

At what rate is the Postoperative Pain Market expected to rise?

The postoperative pain market is expected to rise at a CAGR of 5.2% during the forecast period.

Which Region Dominates the Postoperative Pain Market?

The United States is projected to lead the postoperative pain market over the forecast period.

Table of Content
	1. Executive Summary
	2. Market Overview
	3. Market Background
	4. Global Market Analysis 2018 to 2022 and Forecast, 2023 to 2033
	5. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Drug Class
		5.1. Opioids
		5.2. NSAIDs
		5.3. Local Anaesthetics
		5.4. Tricyclic Antidepressants
		5.5. Antiepileptic Drugs
		5.6. Others
	6. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Route of Administration
		6.1. Oral
		6.2. Intravenous
		6.3. Intramuscular
		6.4. Others
	7. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Distribution Channel
		7.1. Hospital Pharmacies
		7.2. Retail Pharmacies
		7.3. Online Pharmacies
		7.4. Others
	8. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Region
		8.1. North America
		8.2. Latin America
		8.3. Europe
		8.4. South Asia
		8.5. East Asia
		8.6. Oceania
		8.7. Middle East and Africa (MEA)
	9. North America Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
	10. Latin America Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
	11. Europe Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
	12. South Asia Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
	13. East Asia Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
	14. Oceania Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
	15. MEA Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
	16. Key Countries Market Analysis
	17. Market Structure Analysis
	18. Competition Analysis
		18.1. Menarini Group
		18.2. AcelRx Pharmaceuticals
		18.3. Trevena, Inc.
		18.4. Heron Therapeutics
		18.5. Innocoll Pharmaceuticals
		18.6. DURECT Corporation
		18.7. Pacira Pharmaceuticals
		18.8. Baudax Bio
		18.9. Bausch & Lomb
		18.10. Novartis Pharmaceuticals
		18.11. Eli Lilly and Company
		18.12. Teva Pharmaceutical Industries Ltd.
		18.13. Formosa Pharmaceuticals
	19. Assumptions & Acronyms Used
	20. Research Methodology
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Healthcare

Pain Management Devices Market

October 2022

REP-GB-14306

315 pages

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