The global postoperative pain market size is estimated to be valued at US$ 38.43 billion in 2023 and is projected to surpass a valuation of US$ 63.8 billion by 2033. The adoption of postoperative pain drugs is likely to rise at a CAGR of 5.2% during the forecast period. Some major factors propelling the postoperative pain industry growth include:
These factors are propelling the major players to increase their output, which is likely to ultimately result in positive market growth for postoperative pain.
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According to health experts, surgery is linked to long-lasting chronic postoperative pain that typically lasts between three and six months. The demand for postoperative pain is anticipated to rise as phantom pain is one of the frequent postoperative disorders that follows breast surgery, a cesarean section, a thoracotomy, limb amputation, or inguinal hernia repair. Numerous studies carried out in nations with highly established healthcare systems have shown that between one-third and fifty percent of patients do not have adequate postoperative pain management.
The global market for postoperative pain treatments is predicted to experience growth over the forecast period due to an increase in surgical procedures and the intensity of postoperative pain. The global postoperative pain treatment market is anticipated to grow as a result of the development of numerous novel medications. Wide safety margins and advantageous characteristics are being used in the development of new medications.
The importance of non-opioid adjuncts and alternatives has increased for postoperative pain management. Examples of medications that have been popular in the postoperative pain market include intravenous (IV) acetaminophen, non-steroidal anti-inflammatory medicines (NSAIDs), magnesium, ketamine, dexmedetomidine, and liposomal bupivacaine. As a result, postoperative pain therapies now predominate in both emerging and developed markets due to innovative drugs, rising demand, better access, and improved pain management.
| Attribute | Details |
|---|---|
| Postoperative Pain Market Size (2023) | US$ 38.43 billion |
| Postoperative Pain Projected Market Value (2033) | US$ 63.8 billion |
| Global Postoperative Pain CAGR (2023 to 2033) | 5.2% |
| Market Share of Top 5 Countries | 65% |
Principal Consultant
Historically, the demand for postoperative pain drugs increased at a CAGR of 4.7% from 2018 to 2022. The market for postoperative pain was worth US$ 30.4 billion in 2018, the market surpassed US$ 36.53 billion by 2022. The demand for postoperative pain treatment is anticipated to increase in the future due to an increase in the number of traffic accidents, relative trauma injuries, and relative trauma injuries.
| Attribute | Valuation |
|---|---|
| 2025 | US$ 42.53 billion |
| 2028 | US$ 49.52 billion |
| 2032 | US$ 60.65 billion |
The market is anticipated to grow at a CAGR of 5.2% from 2023 to 2033, surpassing US$ 63.8 billion by 2033.
According to projections, the USA is likely to control 87.9% of the market for postoperative pain in North America by 2022. The adoption of opioid treatment is anticipated to lessen the opioid epidemic's rising prevalence in North America, particularly in the United States. For instance, more than 200 million opioid medications were prescribed and given to patients in the United States in 2018.
Furthermore, it is anticipated that the usage of postoperative pain medications would rise in this region due to the strong drug pipeline with effective medications up for FDA clearance. Patients' attitudes have improved in the United States as a result of better compliance with pain treatment suggestions. The country's demand for postoperative pain management pharmaceuticals is probably going to rise as a result of these figures, which will help the industry grow.
Several industry participants are putting strategic plans into action, which is helping the market expand. For instance, Allay Therapeutics, a clinical-stage biotechnology company that has been at the forefront of developing ultra-sustained analgesic products to revolutionize postsurgical pain management and recovery, released the first-ever clinical data demonstrating non-opioid pain relief lasting two weeks after a single administration in May 2021.
In 2022, Germany is anticipated to represent 26.9% of the market for postoperative pain in Europe. The market has grown due to the increasing prevalence and severity of postoperative pain, the launch of promising medications, an increase in surgical operations, and a high rate of pain procedures in developed nations like Germany.
Demand for postoperative pain medications is rising across Germany as opioid maintenance therapy (OMT) for treating opioid dependence (OD) becomes more widely accepted.
Due to the country's rising surgical rate, the postoperative pain market in South Korea is anticipated to grow at a 6.3% CAGR during the forecast period. Many manufacturers of painkillers are forming partnerships, and distribution agreements, and introducing postoperative painkillers in Korea. To increase their position in the worldwide market, major market players are concentrating on various business methods, such as obtaining product approval from regulatory bodies. On May 1, 2018, Grunenthal and Mundipharma struck a distribution and license deal, enabling Mundipharma to market and sell Grunenthal's Tramal (tramadol).
In Japan, opioids are usually prescribed for postoperative pain, but due to an increase in opioid use for non-medical reasons, governing bodies are pressuring doctors to prescribe non-opioid medications, which presents an opportunity for businesses to launch novel non-opioid medications. However, rising concerns about the opioid epidemic in the region and the rising burden of pain on providers of reimbursement are projected to limit the market's ability to grow to some extent.
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By drug class, the opioids segment is predicted to grow at a 4% CAGR throughout the projection period to represent a significant proportion of 61.3% in 2022.
Adults who experience moderate to severe post-operative pain are typically treated with opioids, according to the NIH. As a result, over the past ten years, opioid use has increased. Opioid medications are recognized to be useful for treating postoperative pain and have demonstrated the capacity to support patients in accomplishing their clinical goals based on research studies and current trials.
High Demand for Oral Postoperative Pain Procedures
Oral postoperative pain is anticipated to hold 37.8% of the market in 2022 in terms of route of administration. For patients, especially the elderly, the oral route of administration is more convenient and widely accepted, which contributes to a bigger market share in the postoperative pain market. The high share of the market is ascribed to the segment's simplicity and patients' preference for oral drug administration.
Leading providers of postoperative pain medications are collaborating and acquiring other pharmaceutical firms as their primary approach for the creation of new product lines of pain medications. The demand for painkiller pharmaceuticals is increasing as key stakeholders put more emphasis on the creation of abuse-deterrent opioid drugs and the launch of extended-release non-opioid drugs for post-surgery pain. Similar to this, greater non-narcotic drug discovery and commercialization as well as growing awareness of post-surgery pain management are supporting market expansion.
The market is anticipated to expand as a result of rising acute disease prevalence and an increase in the elderly population in emerging economies. Manufacturers of painkilling drugs should expect great opportunities as patient awareness of procedures and operations grows and as research into pain management expands. Market expansion is anticipated to expand as government efforts to encourage improved postoperative pain management increase.
Recent Developments in the Postoperative Pain Industry:
| Attribute | Details |
|---|---|
| Forecast Period | 2023 to 2033 |
| Historical Data Available for | 2018 to 2022 |
| Market Analysis | US$ billion for Value |
| Key Countries Covered |
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| Key Market Segments Covered |
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| Key Companies Profiled |
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| Report Coverage |
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| Customization & Pricing | Available upon Request |
The postoperative pain market size is anticipated to be US$ 38.43 billion in 2023.
The postoperative pain market size is assessed to be US$ 63.8 billion in 2033.
The postoperative pain market is expected to rise at a CAGR of 5.2% during the forecast period.
The United States is projected to lead the postoperative pain market over the forecast period.
1. Executive Summary | Postoperative Pain Market
1.1. Global Market Outlook
1.2. Demand-side Trends
1.3. Supply-side Trends
1.4. Technology Roadmap Analysis
1.5. Analysis and Recommendations
2. Market Overview
2.1. Market Coverage / Taxonomy
2.2. Market Definition / Scope / Limitations
3. Market Background
3.1. Market Dynamics
3.1.1. Drivers
3.1.2. Restraints
3.1.3. Opportunity
3.1.4. Trends
3.2. Scenario Forecast
3.2.1. Demand in Optimistic Scenario
3.2.2. Demand in Likely Scenario
3.2.3. Demand in Conservative Scenario
3.3. Opportunity Map Analysis
3.4. Investment Feasibility Matrix
3.5. PESTLE and Porter’s Analysis
3.6. Regulatory Landscape
3.6.1. By Key Regions
3.6.2. By Key Countries
3.7. Regional Parent Market Outlook
4. Global Market Analysis 2018 to 2022 and Forecast, 2023 to 2033
4.1. Historical Market Size Value (US$ million) Analysis, 2018 to 2022
4.2. Current and Future Market Size Value (US$ million) Projections, 2023 to 2033
4.2.1. Y-o-Y Growth Trend Analysis
4.2.2. Absolute $ Opportunity Analysis
5. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Drug Class
5.1. Introduction / Key Findings
5.2. Historical Market Size Value (US$ million) Analysis By Drug Class, 2018 to 2022
5.3. Current and Future Market Size Value (US$ million) Analysis and Forecast By Drug Class, 2023 to 2033
5.3.1. Opioids
5.3.2. NSAIDs
5.3.3. Local Anaesthetics
5.3.4. Tricyclic Antidepressants
5.3.5. Antiepileptic Drugs
5.3.6. Others
5.4. Y-o-Y Growth Trend Analysis By Drug Class, 2018 to 2022
5.5. Absolute $ Opportunity Analysis By Drug Class, 2023 to 2033
6. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Route of Administration
6.1. Introduction / Key Findings
6.2. Historical Market Size Value (US$ million) Analysis By Route of Administration, 2018 to 2022
6.3. Current and Future Market Size Value (US$ million) Analysis and Forecast By Route of Administration, 2023 to 2033
6.3.1. Oral
6.3.2. Intravenous
6.3.3. Intramuscular
6.3.4. Others
6.4. Y-o-Y Growth Trend Analysis By Route of Administration, 2018 to 2022
6.5. Absolute $ Opportunity Analysis By Route of Administration, 2023 to 2033
7. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Distribution Channel
7.1. Introduction / Key Findings
7.2. Historical Market Size Value (US$ million) Analysis By Distribution Channel, 2018 to 2022
7.3. Current and Future Market Size Value (US$ million) Analysis and Forecast By Distribution Channel, 2023 to 2033
7.3.1. Hospital Pharmacies
7.3.2. Retail Pharmacies
7.3.3. Online Pharmacies
7.3.4. Others
7.4. Y-o-Y Growth Trend Analysis By Distribution Channel, 2018 to 2022
7.5. Absolute $ Opportunity Analysis By Distribution Channel, 2023 to 2033
8. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Region
8.1. Introduction
8.2. Historical Market Size Value (US$ million) Analysis By Region, 2018 to 2022
8.3. Current Market Size Value (US$ million) Analysis and Forecast By Region, 2023 to 2033
8.3.1. North America
8.3.2. Latin America
8.3.3. Europe
8.3.4. South Asia
8.3.5. East Asia
8.3.6. Oceania
8.3.7. Middle East and Africa (MEA)
8.4. Market Attractiveness Analysis By Region
9. North America Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
9.1. Historical Market Size Value (US$ million) Trend Analysis By Market Taxonomy, 2018 to 2022
9.2. Market Size Value (US$ million) Forecast By Market Taxonomy, 2023 to 2033
9.2.1. By Country
9.2.1.1. The USA
9.2.1.2. Canada
9.2.2. By Drug Class
9.2.3. By Route of Administration
9.2.4. By Distribution Channel
9.3. Market Attractiveness Analysis
9.3.1. By Country
9.3.2. By Drug Class
9.3.3. By Route of Administration
9.3.4. By Distribution Channel
9.4. Key Takeaways
10. Latin America Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
10.1. Historical Market Size Value (US$ million) Trend Analysis By Market Taxonomy, 2018 to 2022
10.2. Market Size Value (US$ million) Forecast By Market Taxonomy, 2023 to 2033
10.2.1. By Country
10.2.1.1. Brazil
10.2.1.2. Mexico
10.2.1.3. Rest of Latin America
10.2.2. By Drug Class
10.2.3. By Route of Administration
10.2.4. By Distribution Channel
10.3. Market Attractiveness Analysis
10.3.1. By Country
10.3.2. By Drug Class
10.3.3. By Route of Administration
10.3.4. By Distribution Channel
10.4. Key Takeaways
11. Europe Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
11.1. Historical Market Size Value (US$ million) Trend Analysis By Market Taxonomy, 2018 to 2022
11.2. Market Size Value (US$ million) Forecast By Market Taxonomy, 2023 to 2033
11.2.1. By Country
11.2.1.1. Germany
11.2.1.2. The United Kingdom
11.2.1.3. France
11.2.1.4. Spain
11.2.1.5. Italy
11.2.1.6. Rest of Europe
11.2.2. By Drug Class
11.2.3. By Route of Administration
11.2.4. By Distribution Channel
11.3. Market Attractiveness Analysis
11.3.1. By Country
11.3.2. By Drug Class
11.3.3. By Route of Administration
11.3.4. By Distribution Channel
11.4. Key Takeaways
12. South Asia Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
12.1. Historical Market Size Value (US$ million) Trend Analysis By Market Taxonomy, 2018 to 2022
12.2. Market Size Value (US$ million) Forecast By Market Taxonomy, 2023 to 2033
12.2.1. By Country
12.2.1.1. India
12.2.1.2. Malaysia
12.2.1.3. Singapore
12.2.1.4. Thailand
12.2.1.5. Rest of South Asia
12.2.2. By Drug Class
12.2.3. By Route of Administration
12.2.4. By Distribution Channel
12.3. Market Attractiveness Analysis
12.3.1. By Country
12.3.2. By Drug Class
12.3.3. By Route of Administration
12.3.4. By Distribution Channel
12.4. Key Takeaways
13. East Asia Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
13.1. Historical Market Size Value (US$ million) Trend Analysis By Market Taxonomy, 2018 to 2022
13.2. Market Size Value (US$ million) Forecast By Market Taxonomy, 2023 to 2033
13.2.1. By Country
13.2.1.1. China
13.2.1.2. Japan
13.2.1.3. South Korea
13.2.2. By Drug Class
13.2.3. By Route of Administration
13.2.4. By Distribution Channel
13.3. Market Attractiveness Analysis
13.3.1. By Country
13.3.2. By Drug Class
13.3.3. By Route of Administration
13.3.4. By Distribution Channel
13.4. Key Takeaways
14. Oceania Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
14.1. Historical Market Size Value (US$ million) Trend Analysis By Market Taxonomy, 2018 to 2022
14.2. Market Size Value (US$ million) Forecast By Market Taxonomy, 2023 to 2033
14.2.1. By Country
14.2.1.1. Australia
14.2.1.2. New Zealand
14.2.2. By Drug Class
14.2.3. By Route of Administration
14.2.4. By Distribution Channel
14.3. Market Attractiveness Analysis
14.3.1. By Country
14.3.2. By Drug Class
14.3.3. By Route of Administration
14.3.4. By Distribution Channel
14.4. Key Takeaways
15. MEA Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
15.1. Historical Market Size Value (US$ million) Trend Analysis By Market Taxonomy, 2018 to 2022
15.2. Market Size Value (US$ million) Forecast By Market Taxonomy, 2023 to 2033
15.2.1. By Country
15.2.1.1. GCC Countries
15.2.1.2. South Africa
15.2.1.3. Israel
15.2.1.4. Rest of MEA
15.2.2. By Drug Class
15.2.3. By Route of Administration
15.2.4. By Distribution Channel
15.3. Market Attractiveness Analysis
15.3.1. By Country
15.3.2. By Drug Class
15.3.3. By Route of Administration
15.3.4. By Distribution Channel
15.4. Key Takeaways
16. Key Countries Market Analysis
16.1. The USA
16.1.1. Pricing Analysis
16.1.2. Market Share Analysis, 2022
16.1.2.1. By Drug Class
16.1.2.2. By Route of Administration
16.1.2.3. By Distribution Channel
16.2. Canada
16.2.1. Pricing Analysis
16.2.2. Market Share Analysis, 2022
16.2.2.1. By Drug Class
16.2.2.2. By Route of Administration
16.2.2.3. By Distribution Channel
16.3. Brazil
16.3.1. Pricing Analysis
16.3.2. Market Share Analysis, 2022
16.3.2.1. By Drug Class
16.3.2.2. By Route of Administration
16.3.2.3. By Distribution Channel
16.4. Mexico
16.4.1. Pricing Analysis
16.4.2. Market Share Analysis, 2022
16.4.2.1. By Drug Class
16.4.2.2. By Route of Administration
16.4.2.3. By Distribution Channel
16.5. Germany
16.5.1. Pricing Analysis
16.5.2. Market Share Analysis, 2022
16.5.2.1. By Drug Class
16.5.2.2. By Route of Administration
16.5.2.3. By Distribution Channel
16.6. The United Kingdom
16.6.1. Pricing Analysis
16.6.2. Market Share Analysis, 2022
16.6.2.1. By Drug Class
16.6.2.2. By Route of Administration
16.6.2.3. By Distribution Channel
16.7. France
16.7.1. Pricing Analysis
16.7.2. Market Share Analysis, 2022
16.7.2.1. By Drug Class
16.7.2.2. By Route of Administration
16.7.2.3. By Distribution Channel
16.8. Spain
16.8.1. Pricing Analysis
16.8.2. Market Share Analysis, 2022
16.8.2.1. By Drug Class
16.8.2.2. By Route of Administration
16.8.2.3. By Distribution Channel
16.9. Italy
16.9.1. Pricing Analysis
16.9.2. Market Share Analysis, 2022
16.9.2.1. By Drug Class
16.9.2.2. By Route of Administration
16.9.2.3. By Distribution Channel
16.10. India
16.10.1. Pricing Analysis
16.10.2. Market Share Analysis, 2022
16.10.2.1. By Drug Class
16.10.2.2. By Route of Administration
16.10.2.3. By Distribution Channel
16.11. Malaysia
16.11.1. Pricing Analysis
16.11.2. Market Share Analysis, 2022
16.11.2.1. By Drug Class
16.11.2.2. By Route of Administration
16.11.2.3. By Distribution Channel
16.12. Singapore
16.12.1. Pricing Analysis
16.12.2. Market Share Analysis, 2022
16.12.2.1. By Drug Class
16.12.2.2. By Route of Administration
16.12.2.3. By Distribution Channel
16.13. Thailand
16.13.1. Pricing Analysis
16.13.2. Market Share Analysis, 2022
16.13.2.1. By Drug Class
16.13.2.2. By Route of Administration
16.13.2.3. By Distribution Channel
16.14. China
16.14.1. Pricing Analysis
16.14.2. Market Share Analysis, 2022
16.14.2.1. By Drug Class
16.14.2.2. By Route of Administration
16.14.2.3. By Distribution Channel
16.15. Japan
16.15.1. Pricing Analysis
16.15.2. Market Share Analysis, 2022
16.15.2.1. By Drug Class
16.15.2.2. By Route of Administration
16.15.2.3. By Distribution Channel
16.16. South Korea
16.16.1. Pricing Analysis
16.16.2. Market Share Analysis, 2022
16.16.2.1. By Drug Class
16.16.2.2. By Route of Administration
16.16.2.3. By Distribution Channel
16.17. Australia
16.17.1. Pricing Analysis
16.17.2. Market Share Analysis, 2022
16.17.2.1. By Drug Class
16.17.2.2. By Route of Administration
16.17.2.3. By Distribution Channel
16.18. New Zealand
16.18.1. Pricing Analysis
16.18.2. Market Share Analysis, 2022
16.18.2.1. By Drug Class
16.18.2.2. By Route of Administration
16.18.2.3. By Distribution Channel
16.19. GCC Countries
16.19.1. Pricing Analysis
16.19.2. Market Share Analysis, 2022
16.19.2.1. By Drug Class
16.19.2.2. By Route of Administration
16.19.2.3. By Distribution Channel
16.20. South Africa
16.20.1. Pricing Analysis
16.20.2. Market Share Analysis, 2022
16.20.2.1. By Drug Class
16.20.2.2. By Route of Administration
16.20.2.3. By Distribution Channel
16.21. Israel
16.21.1. Pricing Analysis
16.21.2. Market Share Analysis, 2022
16.21.2.1. By Drug Class
16.21.2.2. By Route of Administration
16.21.2.3. By Distribution Channel
17. Market Structure Analysis
17.1. Competition Dashboard
17.2. Competition Benchmarking
17.3. Market Share Analysis of Top Players
17.3.1. By Regional
17.3.2. By Drug Class
17.3.3. By Route of Administration
17.3.4. By Distribution Channel
18. Competition Analysis
18.1. Competition Deep Dive
18.1.1. Menarini Group
18.1.1.1. Overview
18.1.1.2. Product Portfolio
18.1.1.3. Profitability by Market Segments
18.1.1.4. Sales Footprint
18.1.1.5. Strategy Overview
18.1.1.5.1. Marketing Strategy
18.1.2. AcelRx Pharmaceuticals
18.1.2.1. Overview
18.1.2.2. Product Portfolio
18.1.2.3. Profitability by Market Segments
18.1.2.4. Sales Footprint
18.1.2.5. Strategy Overview
18.1.2.5.1. Marketing Strategy
18.1.3. Trevena, Inc.
18.1.3.1. Overview
18.1.3.2. Product Portfolio
18.1.3.3. Profitability by Market Segments
18.1.3.4. Sales Footprint
18.1.3.5. Strategy Overview
18.1.3.5.1. Marketing Strategy
18.1.4. Heron Therapeutics
18.1.4.1. Overview
18.1.4.2. Product Portfolio
18.1.4.3. Profitability by Market Segments
18.1.4.4. Sales Footprint
18.1.4.5. Strategy Overview
18.1.4.5.1. Marketing Strategy
18.1.5. Innocoll Pharmaceuticals
18.1.5.1. Overview
18.1.5.2. Product Portfolio
18.1.5.3. Profitability by Market Segments
18.1.5.4. Sales Footprint
18.1.5.5. Strategy Overview
18.1.5.5.1. Marketing Strategy
18.1.6. DURECT Corporation
18.1.6.1. Overview
18.1.6.2. Product Portfolio
18.1.6.3. Profitability by Market Segments
18.1.6.4. Sales Footprint
18.1.6.5. Strategy Overview
18.1.6.5.1. Marketing Strategy
18.1.7. Pacira Pharmaceuticals
18.1.7.1. Overview
18.1.7.2. Product Portfolio
18.1.7.3. Profitability by Market Segments
18.1.7.4. Sales Footprint
18.1.7.5. Strategy Overview
18.1.7.5.1. Marketing Strategy
18.1.8. Baudax Bio
18.1.8.1. Overview
18.1.8.2. Product Portfolio
18.1.8.3. Profitability by Market Segments
18.1.8.4. Sales Footprint
18.1.8.5. Strategy Overview
18.1.8.5.1. Marketing Strategy
18.1.9. Bausch & Lomb
18.1.9.1. Overview
18.1.9.2. Product Portfolio
18.1.9.3. Profitability by Market Segments
18.1.9.4. Sales Footprint
18.1.9.5. Strategy Overview
18.1.9.5.1. Marketing Strategy
18.1.10. Novartis Pharmaceuticals
18.1.10.1. Overview
18.1.10.2. Product Portfolio
18.1.10.3. Profitability by Market Segments
18.1.10.4. Sales Footprint
18.1.10.5. Strategy Overview
18.1.10.5.1. Marketing Strategy
18.1.11. Eli Lilly and Company
18.1.11.1. Overview
18.1.11.2. Product Portfolio
18.1.11.3. Profitability by Market Segments
18.1.11.4. Sales Footprint
18.1.11.5. Strategy Overview
18.1.11.5.1. Marketing Strategy
18.1.12. Teva Pharmaceutical Industries Ltd.
18.1.12.1. Overview
18.1.12.2. Product Portfolio
18.1.12.3. Profitability by Market Segments
18.1.12.4. Sales Footprint
18.1.12.5. Strategy Overview
18.1.12.5.1. Marketing Strategy
18.1.13. Formosa Pharmaceuticals
18.1.13.1. Overview
18.1.13.2. Product Portfolio
18.1.13.3. Profitability by Market Segments
18.1.13.4. Sales Footprint
18.1.13.5. Strategy Overview
18.1.13.5.1. Marketing Strategy
19. Assumptions & Acronyms Used
20. Research Methodology
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Postoperative Pain Market
