Polyether Ether Ketone (PEEK) Interbody Devices Market Outlook

The global polyether ether ketone (PEEK) interbody devices market is to advance at a 7.4% CAGR from 2023 to 2033. Polyether ether ketone interbody device sales are to increase to US$ 4525 million by 2033, from US$ 2207.89 million in 2023.

PEEK is a high-performance semi-crystalline engineering thermoplastic with superior chemical resistance, low moisture uptake, outstanding fire performance, exceptional mechanical strength across a wide temperature range, and good dimensional stability.

Strengthening demand for polyether ether ketone from the electronics, automotive, and aerospace industries, as well as rising development, may fuel expansion in the polyether ether ketone (PEEK) interbody devices market over the forecast period.

Polyether ether ketone interbody devices currently account for 20.3% of the global market for orthopedic trauma devices. The growing senior population, as well as their vulnerability to various backbone and spinal cord ailments, are positively influencing the global polyether ether ketone interbody devices demand.

The development of spine surgery has led to a rise in the adoption of polyether ether ketone interbody devices. These devices are utilized to help with spine fusion. These operations are used to halt a painful spinal section from moving.

PEEK interbody devices, which were initially created in the United States for the aerospace sector, are now being employed in the medical area to aid in a number of surgical procedures. These PEEK interbody implants are bone-friendly and compatible with diagnostic imaging.

Attributes Details
Polyether Ether Ketone (PEEK) Interbody Devices Market CAGR (From 2023 to 2033) 7.4%
Polyether Ether Ketone (PEEK) Interbody Devices Market Size (2023) US$ 2207.89 million
Polyether Ether Ketone (PEEK) Interbody Devices Market Size (2033) US$ 4525 million
Global Market Absolute Dollar Growth (US$ million/billion) US$ 176 million

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Demand for Polyether Ether Ketone Interbody Devices (2017 to 2022) vs Economic Outlook (2023 to 2033)

PEEK interbody cage system, also known as PEEK spinal cages, is deployed during spinal fusion surgeries to substitute a damaged spinal disc and generated an ideal environment for two vertebrae to join. When the spine is harmed by a degenerative disorder or is harmed, fusion is advised. From 2017 to 2022, the polyether ether ketone interbody devices market experienced a CAGR of 6.7%, achieving revenue of US$ 2040.7 million in 2022.

PEEK interbody devices have been a significant development in the clinical industry as they are being used by many medical care settings to streamline their spinal implantation procedures. Given that they are constructed of natural thermoplastic polymers and are environmentally friendly.

Solid-state machining is simple for PEEK. A CNC milling machine, for instance, can be used to machine PEEK-filled grades to produce high-quality, stable plastic parts. Due to its high performance, it is frequently utilized in biological applications such as orthopaedic surgery, spine surgery, and maxillofacial surgery.

The global polyether ether ketone interbody devices market is estimated to reach revenue of US$ 4525 million by 2033, progressing at a CAGR of 7.4% between 2023 and 2033.

How Have the Trends in the Polyether Ether Ketone (PEEK) Interbody Devices Market Tanked?

The market notices a decrease in BPS values, and the reasons for the decrease include the high processing temperature needed for polymer polyetheretherketone (PEEK) compared to accessible thermoplastics, as well as the expensive price of PEEK interbody devices. These elements limit the rate of product acceptance and consequently limit polyether ether ketone (PEEK) interbody devices market expansion.

The polyether ether ketone interbody devices market is susceptible to changes in accordance with macroeconomic and industrial norms, with regard to the legal requirements, safety requirements, and licencing of medical devices.

Due to improvements in material development and the increasing use of hybrid material devices, PEEK interbody implants have the properties of being radiolucent and having a lower elastic modulus, which are likely to favor patients.

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Notable Motivating Factors Lifting Demand for Polyether Ether Ketone Interbody Devices

Sales of PEEK Interbody Devices Accelerated by Spinal Implant Progression

As the number of elderly people increases globally, spinal disorders have become more common. In order to find fresh solutions to the issue, healthcare specialists have intensified their research efforts. This research led to the development of PEEK interbody devices, the first of which were used in the 1980s and gained considerable clinical acceptance later.

The popularity of PEEK interbody devices for spine procedures has been supported by the availability of a bone-like modulus, high radiolucency to ensure precision and high biocompatibility, and polyether ether ketone (PEEK) interbody devices market trend are projected to continue during the forecast period.

Demand for Organic Polymers is Sprouting as PEEK Interbody Device Application is Spreading

Recent years have seen increased environmental concerns over the use of synthetic polymers in medical PEEK interbody implants, which has improved the outlook for organic polymer growth. PEEK interbody devices are a class of organic thermoplastic polymers having a V-O flammability rating, meaning that they produce few dangerous emissions when exposed to flames. This characteristic has made it a popular material selection for a range of end-use applications.

The ability to recycle polyether ether ketone thermoplastics may expand their application in the mass production of polyether ether ketone interbody devices in the healthcare sector.

Sales of Polyether Ether Ketone Interbody Devices may Be Empowered by the Demand Growth for Less Invasive Surgery

The development of minimally invasive spine procedures is the focus of recent surgical advancements aimed at reducing patient trauma. With minimally invasive spine implants, PEEK interbody implants are being used to decrease tissue dissection and nerve root retraction.

The well-known PEEK interbody implants manufacturer, Vertebral Technologies Inc. concentrates on minimally invasive interbody devices. The Interfuse Interbody System, which uses a less invasive method to construct a sizable anterior lumbar PEEK interbody cage system footprint, is one of its product lines.

Challenges Holding Back Sales of Polyether Ether Ketone Interbody Devices

PEEK Interbody Device Sales May Be Affected by High Manufacturing Costs

Since PEEK interbody devices are prevalently complex and difficult to get, healthcare organizations must put aside a significant percentage of their money to purchase them. As a result, many practitioners are hesitant to make investments in these tools, limiting their ability to expand.

Due to the high manufacturing expenses, the price of polyether ether ketone is high, curtailing its use in diverse applications. As a result, polyether ether ketone (PEEK) interbody devices market expansion is probably going to be slow.

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Segmentation Outlook

Which End User Is Responsible For The Rising Consumption Of Polyether Ether Ketone Interbody Devices?

Attributes Details
Top End User Hospitals
CAGR % 2017 to 2022 8.3%
CAGR % 2023 to End of Forecast (2033) 8.8%

PEEK Interbody Devices are Performing well due to Rising Hospital Demand.

Hospitals’ polyether ether ketone applications may account for 48.9% of the market. Hospitals lead the market due to the spread of healthcare settings in developed economies and an increase in hospitalisations as a result of a rise in the incidence of road accidents and other sports injuries.

Short wait times for patients and better trauma care arise from improved hospital infrastructure and hospital expansion. PEEK interbody fusion devices are becoming common in specialist clinics. In 2023, specialty clinics are expected to account for 30.4% of the global market share, while ambulatory surgical centres to account for 20.8% of the global market share.

Attributes Details
Top Product PEEK Interbody Fusion Devices
CAGR % 2017 to 2022 6.7%
CAGR % 2023 to End of Forecast (2033) 7.4%

Regional Outlook

Country The United State
HCAGR (From 2017 to 2022) 5.9%
CAGR (From 2023 to 2033) 6.9%
Country The United Kingdom
HCAGR (From 2017 to 2022) 6.6%
CAGR (From 2023 to 2033) 7.1%
Country China
HCAGR (From 2017 to 2022) 10.3%
CAGR (From 2023 to 2033) 9.5%
Country Germany
HCAGR (From 2017 to 2022) 9.2%
CAGR (From 2023 to 2033) 9.7%
Country Canada
HCAGR (From 2017 to 2022) 9.7%
CAGR (From 2023 to 2033) 8.8%

How Powerful is the United States Polyether Ether Ketone (PEEK) Interbody Devices Market?

Attributes Details
The United States Market Size (US$ million/ billion) by End of Forecast Period (2033) US$ 2800.5 million
The United States Market Absolute Dollar Growth (US$ million/billion) US$ 99.3 million

PEEK Interbody Device Consumption Driven by the Increasing Degenerative Disc Disease Cases.

The market in the United States may produce significant revenue among all nations and is anticipated to expand at a healthy rate due to its high consumption rate. In contrast to the 500,000 persons who have spinal stenosis, more than 3% of people in America have degenerative disc disease.

Also, the PEEK interbody devices market in the nation is reaching new heights thanks to the FDA's growing approval rate. These advancements are fantastic for polyether ether ketone interbody devices to proliferate around America market for the anticipated time period.

Attributes Details
Canada Market Size (US$ million/ billion) by End of Forecast Period (2033) US$ 316 million
Canada Market Absolute Dollar Growth (US$ million/billion) US$ 15.50 million

Canada polyether ether ketone interbody devices market is predicted to increase rapidly by 2033. Due to the high frequency of degenerative disc disease, patients are seeking therapy, which is increasing adoption across healthcare settings.

The polyether ether ketone (PEEK) interbody devices market is to grow as a result of increased product adoption in the automotive industry. This pattern indicates that PEEK interbody devices may grow in Canada market throughout the anticipated timeframe of 2023 to 2033.

Why Should Polyether Ether Ketone (PEEK) Interbody Devices Manufacturers Focus on the United Kingdom?

Attributes Details
The United Kingdom Market Size (US$ million/ billion) by End of Forecast Period (2033) US$ 46.9 million
The United Kingdom Market Absolute Dollar Growth (US$ million/billion) US$ 1.7 million

PEEK is Becoming Increasingly used in a Variety of Industries.

Many new uses for this polymer in the automotive, oil & gas, electronics, medical, and aerospace sectors may further boost the polyether ether ketone (PEEK) interbody devices market in Europe. In the plastics business, polyether ether ketone (PEEK) is recognised as a prominent high-performance polymer.

How are Polyether Ether Ketone Interbody Devices Sales to Fare in Germany?

Attributes Details
Germany Market Size (US$ million/ billion) by End of Forecast Period (2033) US$ 122.8 million
Germany Market Absolute Dollar Growth (US$ million/billion) US$ 5.2 million

Strict Controls are in Place to Decrease CO2 Emissions.

PEEK is emerging as an eco-friendly alternative in a variety of applications. Its use produces fewer carbon emissions than other polymers such as polyester laminate, polyvinyl chloride, and polystyrene. By providing superior corrosion resistance, PEEK extends the service life of the goods in which it is utilised. It works well in hot environments. It is one of the most adaptable products in terms of production design freedom, resulting in less reliance on manpower.

Why is China Witnessing a Strong Upsurge in Demand for Polyether Ether Ketone Interbody Devices?

Attributes Details
China Market Size (US$ million/ billion) by End of Forecast Period (2033) US$ 576.1 million
China Market Absolute Dollar Growth (US$ million/billion US$ 28.5 million

Demand for PEEK Interbody Devices Stimulated by the Presence of Market Participants and Growing Healthcare Sector

In East Asia, China is the country with a considerable polyether ether ketone interbody devices market. China is expected to have promising growth as a result of growing awareness of healthcare services and expanding infrastructure.

The adoption of contemporary technologies in medical equipment may help China market generate sizable profits in the upcoming years. The expanding healthcare industry and the presence of significant polyether ether ketone interbody device manufacturers have increased demand for PEEK interbody devices.

Many polyether ether ketone interbody devices manufacturers, notably Medtronic Plc., Stryker Corporation, Zimmer Biomet Holdings Inc., and Alphatec Holdings Inc., have established supremacy in East Asia market, with the majority of their manufacturing facilities in China.

How Do Competitors Have an Effect on the Polyether Ether Ketone (PEEK) Interbody Devices Market?

The polyether ether ketone (PEEK) interbody devices market has become extremely consolidated. Expansion of existing manufacturing capacities, new developments, forays into untapped markets, and enhancement of core strengths are all key considerations for pioneering businesses in the global PEEK interbody devices market.

Since the system's launch, over 84% of chronic back pain-treated patients with Medtronic's DTMTM Spinal Cord Stimulation Treatment have reported at least 50% pain relief. This has pushed the business to keep investing in more effective pain control technology.

Recent Developments:

  • Introduction
Date March 2021
Company Evonik
Details Evonik developed a new 3D printing filament based on PEEK INFINAM PEEK. INFINAM PEEK is compatible with extrusion-based 3D printing processes (FFF/FDM)
  • Partnerships/Joint Venture
Date March 2022
Company Mitsubishi Chemical Advanced Materials
Details Solvay teamed with Mitsubishi Chemical Advanced Materials to recycle end-of-life medical components in order to recycle and recover additional high-performance polymers, such as KetaSpire polyetheretherketone (PEEK).
Date January 2020
Company Yingkou Xingfu Chemical Company Limited
Details Yingkou Xingfu Chemical Company Limited and Victrex Hong Kong Limited formed a joint venture to establish a manufacturing facility for a novel PEEK polymer in Liaoning, China. This arrangement may assist both organisations in meeting the needs of their customers.

Prominent Polyether Ether Ketone (PEEK) Interbody Devices Manufacturers

  • Zimmer Biomet Holdings. Inc.
  • Medtronic Plc.
  • Stryker Corporation
  • B. Braun Melsungen AG
  • SeaSpine Holdings Corporation
  • Polymer Company Limited Shandong Weigao Group Medical
  • Alphatec Holdings Inc.
  • Xtant Medical Holdings, Inc.
  • Life Spine, Inc.

Key Segments  

By Product:

  • Posterolateral Fusion Devices
  • Interbody Fusion Devices
  • Anterior Lumbar Interbody Fusion Devices (ALIF)
  • Extreme Lateral Interbody Fusion Devices (XLIF)
  • Posterior Lumbar Interbody Fusion Devices (PLIF)
  • Transforaminal Lumbar Interbody Fusion Devices (TLIF)
  • Other Devices

By End Use:

  • Hospitals
  • Ambulatory Surgical Centers
  • Specialty Clinics

By Region:

  • North America
  • Latin America
  • Europe
  • East Asia
  • South Asia & Pacific
  • The Middle East & Africa (MEA)

Frequently Asked Questions

What is the Projected CAGR of the Market by 2033?

The projected CAGR of the market by 2033 is 7.4%.

What is the Expected Market value for 2033?

The projected market value for 2033 is US$ 4,525 million.

What is the Current Market Valuation of the Market?

The market is estimated to secure a valuation of US$ 2,207.89 million in 2023.

Which Industry is the Key Consumer of the Polyether Ether Ketone (PEEK) Interbody Devices?

The healthcare industry is the key consumer.

Why is the Asia Pacific Market Growing Remarkably Fast in the Market?

Due to the increasing prevalence of spinal disorders.

Table of Content

1. Executive Summary | Polyether Ether Ketone (PEEK) Interbody Devices Market

    1.1. Global Market Outlook

    1.2. Demand-side Trends

    1.3. Supply-side Trends

    1.4. Technology Roadmap Analysis

    1.5. Analysis and Recommendations

2. Market Overview

    2.1. Market Coverage / Taxonomy

    2.2. Market Definition / Scope / Limitations

3. Market Background

    3.1. Market Dynamics

        3.1.1. Drivers

        3.1.2. Restraints

        3.1.3. Opportunity

        3.1.4. Trends

    3.2. Scenario Forecast

        3.2.1. Demand in Optimistic Scenario

        3.2.2. Demand in Likely Scenario

        3.2.3. Demand in Conservative Scenario

    3.3. Opportunity Map Analysis

    3.4. Investment Feasibility Matrix

    3.5. PESTLE and Porter’s Analysis

    3.6. Regulatory Landscape

        3.6.1. By Key Regions

        3.6.2. By Key Countries

    3.7. Regional Parent Market Outlook

4. Global Market Analysis 2018 to 2022 and Forecast, 2023 to 2033

    4.1. Historical Market Size Value (US$ Million) Analysis, 2018 to 2022

    4.2. Current and Future Market Size Value (US$ Million) Projections, 2023 to 2033

        4.2.1. Y-o-Y Growth Trend Analysis

        4.2.2. Absolute $ Opportunity Analysis

5. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Product Type

    5.1. Introduction / Key Findings

    5.2. Historical Market Size Value (US$ Million) Analysis By Product Type, 2018 to 2022

    5.3. Current and Future Market Size Value (US$ Million) Analysis and Forecast By Product Type, 2023 to 2033

        5.3.1. Posterolateral Fusion Devices

        5.3.2. Interbody Fusion Devices

            5.3.2.1. Anterior Lumbar Interbody Fusion Devices

            5.3.2.2. Extreme Lateral Interbody Fusion Devices

            5.3.2.3. Posterior Lumbar Interbody Fusion Devices

            5.3.2.4. Transforaminal Lumbar Interbody Fusion Devices

            5.3.2.5. Other Devices

    5.4. Y-o-Y Growth Trend Analysis By Product Type, 2018 to 2022

    5.5. Absolute $ Opportunity Analysis By Product Type, 2023 to 2033

6. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By End-Users

    6.1. Introduction / Key Findings

    6.2. Historical Market Size Value (US$ Million) Analysis By End-Users, 2018 to 2022

    6.3. Current and Future Market Size Value (US$ Million) Analysis and Forecast By End-Users, 2023 to 2033

        6.3.1. Hospitals

        6.3.2. Ambulatory Surgical Centers

        6.3.3. Specialty Clinics

    6.4. Y-o-Y Growth Trend Analysis By End-Users, 2018 to 2022

    6.5. Absolute $ Opportunity Analysis By End-Users, 2023 to 2033

7. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Region

    7.1. Introduction

    7.2. Historical Market Size Value (US$ Million) Analysis By Region, 2018 to 2022

    7.3. Current Market Size Value (US$ Million) Analysis and Forecast By Region, 2023 to 2033

        7.3.1. North America

        7.3.2. Latin America

        7.3.3. Europe

        7.3.4. Asia Pacific

        7.3.5. Middle East and Africa

    7.4. Market Attractiveness Analysis By Region

8. North America Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country

    8.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022

    8.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033

        8.2.1. By Country

            8.2.1.1. The USA

            8.2.1.2. Canada

        8.2.2. By Product Type

        8.2.3. By End-Users

    8.3. Market Attractiveness Analysis

        8.3.1. By Country

        8.3.2. By Product Type

        8.3.3. By End-Users

    8.4. Key Takeaways

9. Latin America Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country

    9.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022

    9.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033

        9.2.1. By Country

            9.2.1.1. Brazil

            9.2.1.2. Mexico

            9.2.1.3. Rest of Latin America

        9.2.2. By Product Type

        9.2.3. By End-Users

    9.3. Market Attractiveness Analysis

        9.3.1. By Country

        9.3.2. By Product Type

        9.3.3. By End-Users

    9.4. Key Takeaways

10. Europe Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country

    10.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022

    10.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033

        10.2.1. By Country

            10.2.1.1. United Kingdom

            10.2.1.2. Spain

            10.2.1.3. Germany

            10.2.1.4. Italy

            10.2.1.5. France

            10.2.1.6. Rest of Europe

        10.2.2. By Product Type

        10.2.3. By End-Users

    10.3. Market Attractiveness Analysis

        10.3.1. By Country

        10.3.2. By Product Type

        10.3.3. By End-Users

    10.4. Key Takeaways

11. Asia Pacific Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country

    11.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022

    11.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033

        11.2.1. By Country

            11.2.1.1. China

            11.2.1.2. Japan

            11.2.1.3. India

            11.2.1.4. South Korea

            11.2.1.5. Rest of Asia Pacific

        11.2.2. By Product Type

        11.2.3. By End-Users

    11.3. Market Attractiveness Analysis

        11.3.1. By Country

        11.3.2. By Product Type

        11.3.3. By End-Users

    11.4. Key Takeaways

12. Middle East and Africa Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country

    12.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022

    12.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033

        12.2.1. By Country

            12.2.1.1. South Africa

            12.2.1.2. GCC Countries

            12.2.1.3. Rest of Middle East and Africa

        12.2.2. By Product Type

        12.2.3. By End-Users

    12.3. Market Attractiveness Analysis

        12.3.1. By Country

        12.3.2. By Product Type

        12.3.3. By End-Users

    12.4. Key Takeaways

13. Key Countries Market Analysis

    13.1. USA

        13.1.1. Pricing Analysis

        13.1.2. Market Share Analysis, 2022

            13.1.2.1. By Product Type

            13.1.2.2. By End-Users

    13.2. Canada

        13.2.1. Pricing Analysis

        13.2.2. Market Share Analysis, 2022

            13.2.2.1. By Product Type

            13.2.2.2. By End-Users

    13.3. Brazil

        13.3.1. Pricing Analysis

        13.3.2. Market Share Analysis, 2022

            13.3.2.1. By Product Type

            13.3.2.2. By End-Users

    13.4. Mexico

        13.4.1. Pricing Analysis

        13.4.2. Market Share Analysis, 2022

            13.4.2.1. By Product Type

            13.4.2.2. By End-Users

    13.5. United Kingdom

        13.5.1. Pricing Analysis

        13.5.2. Market Share Analysis, 2022

            13.5.2.1. By Product Type

            13.5.2.2. By End-Users

    13.6. Spain

        13.6.1. Pricing Analysis

        13.6.2. Market Share Analysis, 2022

            13.6.2.1. By Product Type

            13.6.2.2. By End-Users

    13.7. Germany

        13.7.1. Pricing Analysis

        13.7.2. Market Share Analysis, 2022

            13.7.2.1. By Product Type

            13.7.2.2. By End-Users

    13.8. Italy

        13.8.1. Pricing Analysis

        13.8.2. Market Share Analysis, 2022

            13.8.2.1. By Product Type

            13.8.2.2. By End-Users

    13.9. France

        13.9.1. Pricing Analysis

        13.9.2. Market Share Analysis, 2022

            13.9.2.1. By Product Type

            13.9.2.2. By End-Users

    13.10. China

        13.10.1. Pricing Analysis

        13.10.2. Market Share Analysis, 2022

            13.10.2.1. By Product Type

            13.10.2.2. By End-Users

    13.11. Japan

        13.11.1. Pricing Analysis

        13.11.2. Market Share Analysis, 2022

            13.11.2.1. By Product Type

            13.11.2.2. By End-Users

    13.12. India

        13.12.1. Pricing Analysis

        13.12.2. Market Share Analysis, 2022

            13.12.2.1. By Product Type

            13.12.2.2. By End-Users

    13.13. South Korea

        13.13.1. Pricing Analysis

        13.13.2. Market Share Analysis, 2022

            13.13.2.1. By Product Type

            13.13.2.2. By End-Users

    13.14. South Africa

        13.14.1. Pricing Analysis

        13.14.2. Market Share Analysis, 2022

            13.14.2.1. By Product Type

            13.14.2.2. By End-Users

    13.15. GCC Countries

        13.15.1. Pricing Analysis

        13.15.2. Market Share Analysis, 2022

            13.15.2.1. By Product Type

            13.15.2.2. By End-Users

14. Market Structure Analysis

    14.1. Competition Dashboard

    14.2. Competition Benchmarking

    14.3. Market Share Analysis of Top Players

        14.3.1. By Regional

        14.3.2. By Product Type

        14.3.3. By End-Users

15. Competition Analysis

    15.1. Competition Deep Dive

        15.1.1. Zimmer Biomet Holdings Inc.

            15.1.1.1. Overview

            15.1.1.2. Product Portfolio

            15.1.1.3. Profitability by Market Segments

            15.1.1.4. Sales Footprint

            15.1.1.5. Strategy Overview

                15.1.1.5.1. Marketing Strategy

        15.1.2. Medtronic Plc.

            15.1.2.1. Overview

            15.1.2.2. Product Portfolio

            15.1.2.3. Profitability by Market Segments

            15.1.2.4. Sales Footprint

            15.1.2.5. Strategy Overview

                15.1.2.5.1. Marketing Strategy

        15.1.3. Stryker Corporation

            15.1.3.1. Overview

            15.1.3.2. Product Portfolio

            15.1.3.3. Profitability by Market Segments

            15.1.3.4. Sales Footprint

            15.1.3.5. Strategy Overview

                15.1.3.5.1. Marketing Strategy

        15.1.4. B. Braun Melsungen AG

            15.1.4.1. Overview

            15.1.4.2. Product Portfolio

            15.1.4.3. Profitability by Market Segments

            15.1.4.4. Sales Footprint

            15.1.4.5. Strategy Overview

                15.1.4.5.1. Marketing Strategy

        15.1.5. SeaSpine Holdings Corporation

            15.1.5.1. Overview

            15.1.5.2. Product Portfolio

            15.1.5.3. Profitability by Market Segments

            15.1.5.4. Sales Footprint

            15.1.5.5. Strategy Overview

                15.1.5.5.1. Marketing Strategy

        15.1.6. Alphatec Holding Inc.

            15.1.6.1. Overview

            15.1.6.2. Product Portfolio

            15.1.6.3. Profitability by Market Segments

            15.1.6.4. Sales Footprint

            15.1.6.5. Strategy Overview

                15.1.6.5.1. Marketing Strategy

        15.1.7. Xtant Medical Holding, Inc.

            15.1.7.1. Overview

            15.1.7.2. Product Portfolio

            15.1.7.3. Profitability by Market Segments

            15.1.7.4. Sales Footprint

            15.1.7.5. Strategy Overview

                15.1.7.5.1. Marketing Strategy

        15.1.8. Life Spine, Inc.

            15.1.8.1. Overview

            15.1.8.2. Product Portfolio

            15.1.8.3. Profitability by Market Segments

            15.1.8.4. Sales Footprint

            15.1.8.5. Strategy Overview

                15.1.8.5.1. Marketing Strategy

        15.1.9. Beijing Fule Science & Technology Development Co., Ltd.

            15.1.9.1. Overview

            15.1.9.2. Product Portfolio

            15.1.9.3. Profitability by Market Segments

            15.1.9.4. Sales Footprint

            15.1.9.5. Strategy Overview

                15.1.9.5.1. Marketing Strategy

        15.1.10. Double Medical Technology Inc.

            15.1.10.1. Overview

            15.1.10.2. Product Portfolio

            15.1.10.3. Profitability by Market Segments

            15.1.10.4. Sales Footprint

            15.1.10.5. Strategy Overview

                15.1.10.5.1. Marketing Strategy

        15.1.11. Zavation LLC

            15.1.11.1. Overview

            15.1.11.2. Product Portfolio

            15.1.11.3. Profitability by Market Segments

            15.1.11.4. Sales Footprint

            15.1.11.5. Strategy Overview

                15.1.11.5.1. Marketing Strategy

        15.1.12. DiFusion Technologies, Inc.

            15.1.12.1. Overview

            15.1.12.2. Product Portfolio

            15.1.12.3. Profitability by Market Segments

            15.1.12.4. Sales Footprint

            15.1.12.5. Strategy Overview

                15.1.12.5.1. Marketing Strategy

        15.1.13. Canwell Medical Co.,Ltd.

            15.1.13.1. Overview

            15.1.13.2. Product Portfolio

            15.1.13.3. Profitability by Market Segments

            15.1.13.4. Sales Footprint

            15.1.13.5. Strategy Overview

                15.1.13.5.1. Marketing Strategy

16. Assumptions & Acronyms Used

17. Research Methodology

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