Pharmaceutical Caps and Closures Market Outlook 2025 to 2035

The pharmaceutical caps and closures market comprises primary packaging components designed to seal, protect, and maintain the sterility and integrity of pharmaceutical products, including vials, bottles, syringes, and IV containers.

These closuresranging from screw caps, flip-off caps, child-resistant closures, and tamper-evident seals, to rubber and aluminum stoppersplay a critical role in dosage accuracy, contamination prevention, and compliance with Good Manufacturing Practices (GMP) and regulatory standards.

In 2025, the global pharmaceutical caps and closures market is projected to reach approximately USD 2,844.8 million, with expectations to grow to around USD 4,723.0 million by 2035, reflecting a Compound Annual Growth Rate (CAGR) of 5.2% during the forecast period.

Key Market Metrics

Metric Value
Market Size in 2025 USD 2,844.8 Million
Projected Market Size in 2035 USD 4,723.0 Million
CAGR (2025 to 2035) 5.2%

The market is growing in response to increasing drug production, injectable therapies, biologics, and demand for smart and sustainable packaging solutions in the pharmaceutical industry.

Explore FMI!

Book a free demo

Regional Market Trends

North America

North America dominates the market owing to its vast pharmaceutical manufacturing, high parenteral unit dose drug consumption, and stringent FDA packaged regulations. As well as being in demand across US and Canadian markets, particularly in packaging for opioids and controlled drugs for tamper-evident and child-resistant closures, there is increasing use of prefillable syringe caps and sterile stoppers for biologics and mRNA therapies.

Europe

It is a compliance-focused and sustainability-aware market, with countries like Germany, Switzerland, France, and the UK stressing the use of green materials, recyclability, and cleanroom-compliant closure. EU GMP regulations and the EU Falsified Medicines Directive are driving development of tamper-evident serialization cap solutions, especially for over-the-counter (OTC) and high-risk prescription drugs.

Asia-Pacific

Asia-Pacific will witness the fastest growth due to rapid growth in pharmaceutical manufacturing, rising demand for healthcare, and substantial investments in contract manufacturing organizations (CMOs), particularly in India, China, Japan, and South Korea. The region is focusing on glass vial compatibility, elastomeric closures, and automation-ready cap manufacturing lines.

Challenges and Opportunities

Challenges

Regulatory Stringency and Compatibility Issues with Drug Formulations

The pharmaceutical caps and closures market is restricted by the stringent guidelines laid down by FDA, EMA, and USP and refers to the need for container-closure integrity (CCI) for sterile pharmaceuticals and biologics. Closures should also be compatible with extremely sensitive or reactive API (Active Pharmaceutical Ingredients, such as biologics or inhalables) and cannot leach, interact or contaminate the product.

Supporting tamper evidence, child resistance, and counterfeiting resistant features within a single closure system creates product complexity. This further restricts materials and processes as well as introduces the need for closures resistant to injectable drug particulate generation.

Opportunities

Rise of Biologics, Smart Closures, and Sustainable Packaging Trends

The market is evolving at a blistering rate with the advent of parenteral medications, biologics, prefilled syringes and personalized medicine, which all requiring high-performance packaging sealing technology. Innovations in multi-dose vial closures, flip-off seals, aluminum-plastic hybrids and fluoropolymer-coated elastomeric stoppers are enabling enhanced drug stability and injection safety.

In addition, rising pharmaceutical sustainability targets drive momentum towards recyclable, bio-based polymers and low-carbon cap production. Moreover, intelligent closures with NFC tags, tamper detection sensors, and dose-tracking functionality are in development to further improve adherence and anti-counterfeiting.

Shifts in the Pharmaceutical Caps and Closures Market from 2020 to 2024 and Future Trends 2025 to 2035

Starting from 2020 to 2024, the market was fueled by the distribution of vaccines from COVID-19, which has a need for sterility, cold chain robustness, and vial integrity. Manufacturers adopted speed-to-market strategies leading to accelerated scaling of rubber stoppers, flip-off seals, and crimp caps. The market, however, was short on raw materials, inconsistent in its quality and had logistical challenges in a strained supply chain.

More use of AI-based quality control and digital serialization of closures, as well as modularity of closure designs for auto injectors, nasal sprays and smart pill bottles will drive the industry as a smart, sustainable and precision-driven ecosystem by 2025 to 2035. Pharmaceutical packaging innovation will also continue to focus on ensuring elderly friendliness, child resistance, and improved compliance in the closure system.

Market Shifts: A Comparative Analysis 2020 to 2024 vs. 2025 to 2035

Market Shift 2020 to 2024 Trends
Regulatory Landscape Compliance with USP <1207>, ISO 8362, and FDA CCI guidelines
Technology Innovations Use of butyl rubber stoppers, aluminum caps, and snap-on lids
Market Adoption Dominant in injectable, OTC tablets, and oral liquids
Sustainability Trends Shift toward PVC-free, phthalate-free caps, and recyclable packs
Market Competition Led by Berry Global, AptarGroup, Gerresheimer, West Pharmaceutical, Bormioli Pharma, SGD Pharma, Datwyler
Consumer Trends Demand for tamper-evidence, portability, and sterility assurance
Market Shift 2025 to 2035 Projections
Regulatory Landscape Integration of AI-driven CCI testing, carbon disclosure, and pharma-grade recycling standards
Technology Innovations Expansion into fluoropolymer-laminated closures, bio-based caps, and NFC-enabled tamper-evidence
Market Adoption Growth into smart packaging, biosimilar drug kits, transdermal patch containers, and inhaler cartridges
Sustainability Trends Adoption of plant-based polymers, closed-loop packaging lines, and caps with end-of-life traceability
Market Competition Entry of biopolymer cap specialists, digital closure startups, and customized CDMO packaging providers
Consumer Trends Preference for smart caps, aging-friendly designs, sustainability labeling, and digital traceability

Country-wise Outlook

United States

The USA pharmaceutical caps and closures market is gradually growing due to the increasing pharmaceutical production, regulatory attention on tamper evident packaging, also the increasing demand for child proof and senior friendly closures.

The growth is also driven by an increase in over-the-counter (OTC) drugs, biologics, and high-volume prescriptions that require secure, leak-proof, and contamination-resistant packaging. Pharmaceutical companies focused on preventing counterfeits and ensuring patient safety are increasingly choosing intelligent closures that feature built-in authentication or tracking functionality.

Country CAGR (2025 to 2035)
USA 4.9%

United Kingdom

UK pharmaceutical caps and closures market is moderate growing on back of increasing demand for safe and compliant packaging from generic and branded pharmaceuticals. Colour-coded, tamper-evident and child-resistant closures are compatible with NHS emphasis on drug safety and error minimization and driving uptake.

Pharmaceutical packagers are being encouraged to transition to recyclable, less bulky closures without compromising security and usability for the aging population through sustainability goals.

Country CAGR (2025 to 2035)
UK 4.4%

European Union

The demand for EU pharmaceutical caps and closures is relatively stable in countries such as Germany, France and Italy. Physical locks, serialization, anti-tampering, and pharmacovigilance per EU regulatory conditions are accelerating the adoption of complex cap and closure technologies.

Plastic-aluminium hybrid caps, flip-off seals, and child-resistant push-and-turn closures are all ubiquitous, seen across oral solid dosages, injectable and liquid syrups. Environmental regulation is also playing a part, encouraging development of compostable and mono-material closure innovations.

Country CAGR (2025 to 2035)
EU 4.3%

Japan

Increasing elderly population, rising consumption of chronic disease therapeutics and recent regulations for accurate dosing and safe drug packaging are the reasons for steady growth of Japan Pharmaceutical Caps and Closures market.

Closure makers are developing closures that have easy-to-hold textures and openings that are easier to pry for the elderly and the children. The shift to portable and unit-dose formats for at-home care is also prompting innovation around closure functionality.

Country CAGR (2025 to 2035)
Japan 4.6%

South Korea

The South Korea pharmaceutical caps and closures market is expected to project steady growth in the coming time with the rising pharmaceutical exports, domestic manufacturing capabilities, and surging demand for sterile and tamper-evident packaging.

The market is benefitting from advancements in barrier properties, flip-top closures and RFID-enabled caps for traceability. Strong uptake across RX and nutraceutical packaging segments.

Country CAGR (2025 to 2035)
South Korea 4.7%

Segmentation Outlook

Screw Caps and Closures Lead the Market with Versatility and Secure Sealing

By Product Market Share (2025)
Screw Caps & Closures 45.0%

These factors are the reason why they are very tightly sealed, easy to use, and can fit in different kinds of containers, for example the bottles and the vials. Screw caps offer a reliable closure that prevents any suffixation, moisture, and air while ensuring that the potency of the drugs is sustained along with stability.

Producers have continued to adapt screw cap configurations to meet shifting needs within the pharmaceutical sector. This includes the integration of child-resistant mechanisms and tamper-evident features that enhance patient safety and meet stringent regulatory standards. As such, the widespread adoption of screw caps across liquid products, solid dosages, and topical applications speaks to their versatility and reliability in protecting product integrity.

Child-Resistant Closures Dominate the Market amid Growing Safety Concerns

By Functionality Market Share (2025)
Child-Resistant 60.0%

Based on functionality, child-resistant closures are expected to hold a dominant position in the pharmaceutical caps and closures market with ~60.0% market share. If you add strict regulatory requirements and heightened sensitivity about not making it possible for youngsters to ingest drugs accidentally, this is driven by. Child-resistant closures are designed so that they are extremely challenging for children under the age of five to open, thereby reducing the risk of poisoning and enhancing safety at home.

Child-resistant design and its implementation has become one of the most prominent priorities of pharmaceutical companies working to meet safety protocols while providing consumer protection. Advancements in technology for this are packages that are easy and convenient for adults particularly for their older or disabled counterparts to open without excessive work. The prevalence of child-resistant closures on prescription and over-the-counter drugs is a testament to their importance as a public health protector.

In a nutshell, the pharmaceutical caps and closures market is premised to evolve significantly, by product type screw caps and closures and child-resistant closures capability-wise. We believe the trend underscores an overall commitment within the industry to medication safety, regulatory compliance and consumer confidence.

With product protection, tamper resistance, safety, and ease-of-use to contend with, ongoing advancements in cap and closure design will be critical to meeting issues and a range of different needs in the global health landscape, as pharmaceutical packaging evolves.

Competitive Outlook

Pharmaceutical caps and closures market is classified into reliability, anti-counterfeiting, hospitalization, extended release contracts, temperature and moisture resistant, and child-resistant packaging for liquid, solid and powder drug formulations. All of these components are vital to the drug keeping its potency, preventing leakage, and ensuring child safety and regulatory standards (FDA, EU, etc.).

Market Share Analysis by Key Players

Company/Organization Name Estimated Market Share (%)
Berry Global Inc. 18-22%
AptarGroup, Inc. 14-18%
Gerresheimer AG 12-16%
West Pharmaceutical Services Inc. 10-14%
Amcor plc 8-12%
Others 26-32%

Key Company & Market Offerings

Company/Organization Name Key Offerings/Activities
Berry Global Inc. In 2024, Berry launched CRC (child-resistant closures) with tamper-evident seals, compatible with HDPE and PET pharma containers, targeting the liquid oral and tablet segment.
AptarGroup, Inc. As of 2024, Aptar expanded its BFS-compatible sterile closures with dose accuracy and re-seal technology, ideal for ophthalmic, nasal, and dermal applications.
Gerresheimer AG In 2023, Gerresheimer introduced flip-off aluminum -plastic combination caps for injectable and lyophilized drugs, ensuring enhanced vial integrity and traceability.
West Pharmaceutical Services Inc. In 2024, West launched NovaPure ® closures with elastomeric coatings, minimizing particle shedding and contamination in biotech and biologic formulations.
Amcor plc As of 2025, Amcor introduced recyclable and aluminum -free closures for syrup bottles and pediatric suspensions, supporting sustainable packaging commitments in regulated markets.

Key Market Insights

Berry Global Inc. (18-22%)

Berry dominates the pharmaceutical caps and closures market with a wide portfolio of threaded, CRC, and snap-on closures, known for cost-efficiency, versatility, and compatibility across oral solid and liquid drug containers.

AptarGroup, Inc. (14-18%)

Aptar leads in innovative dosing and dispensing closures, providing sterile and resealable packaging for nasal sprays, eye drops, and topical treatments, with strong penetration in OTC and prescription markets.

Gerresheimer AG (12-16%)

Gerresheimer focuses on glass vial closures and premium injectable packaging, offering flip-off caps with visual indicators, RFID tags, and tamper-evidence for hospital-grade injectable therapies.

West Pharmaceutical Services Inc. (10-14%)

West excels in biologic and sensitive drug closures, offering low-risk elastomeric stoppers and closures that minimize extractables, leachables, and microbial ingress, especially in biotech and gene therapy segments.

Amcor plc (8-12%)

Amcor is a major innovator in sustainable and regulatory-compliant closures, supplying lightweight, recyclable caps with child-safe mechanisms for pediatric, geriatric, and OTC drug packaging.

Other Key Players (26-32% Combined)

Numerous regional and specialty companies are contributing to innovation in smart caps, tamper-detection features, and user-friendly formats, including:

  • Weener Plastics Group (Custom closures for pharma liquids and nutraceuticals with anti-backflow design)
  • Bormioli Pharma (Sterile closures and aluminum-plastic systems for aseptic fill/finish lines)
  • SGD Pharma (Injection vial closure solutions with rubber stoppers and barrier-coated caps)
  • Vetter Pharma (High-quality combination closures and stoppers for prefilled syringes and cartridges)
  • Tekni-Plex, Inc. (Pharma-grade closure liners and tamper seals with high chemical resistance)

Frequently Asked Questions

What was the overall size of the pharmaceutical caps and closures market in 2025?

The overall market size for pharmaceutical caps and closures market was USD 2,844.8 million in 2025.

How big the pharmaceutical caps and closures market is expected in 2035?

The pharmaceutical caps and closures market is expected to reach USD 4,723.0 million in 2035.

What will drive the demand for pharmaceutical caps and closures market during the forecast period?

Expanding pharmaceutical production, rising demand for secure and tamper-evident packaging, and increasing emphasis on product safety and shelf life will drive market growth.

List the top 5 countries contributing in pharmaceutical caps and closures market?

The top 5 countries which drives the development of pharmaceutical caps and closures market are USA, European Union, Japan, South Korea and UK.

Which segment in type is expected to lead pharmaceutical caps and closures market?

Child-resistant closures expected to grow to command significant share over the assessment period.

Table of Content
  1. Executive Summary
  2. Industry Introduction, including Taxonomy and Market Definition
  3. Pharmaceutical Caps and Closures Market Trends and Success Factors, including Macro-economic Factors, Market Dynamics, and Recent Industry Developments
  4. Global Market Demand Analysis 2020 to 2024 and Forecast 2025 to 2035, including Historical Analysis and Future Projections
  5. Global Market Analysis 2020 to 2024 and Forecast 2025 to 2035
    • Product Type
    • Functionality
    • Material Type
    • Availability
    • Drug Modality
    • Therapeutic Class
    • End Users
  6. Global Market Analysis 2020 to 2024 and Forecast 2025 to 2035, By Product Type
    • Screw Caps & Closure
    • Snap Caps & Closure
    • Push-Pull Caps & Closure
    • Stopper & Seals
    • Others
  7. Global Market Analysis 2020 to 2024 and Forecast 2025 to 2035, By Functionality
    • Child Resistant
    • Tamper-evident
  8. Global Market Analysis 2020 to 2024 and Forecast 2025 to 2035, By Material Type
    • Plastic
    • Elastomer
    • Metal
  9. Global Market Analysis 2020 to 2024 and Forecast 2025 to 2035, By Availability
    • Prescription (Rx) Pharmaceuticals
    • Over-the-Counter (OTC) Pharmaceuticals
  10. Global Market Analysis 2020 to 2024 and Forecast 2025 to 2035, By Drug Modality
    • Small Molecule (Synthetic Drugs)
    • Biopharmaceuticals
  11. Global Market Analysis 2020 to 2024 and Forecast 2025 to 2035, By Therapeutic Class
    • Anticancer Drugs
    • Anti-infective Drugs
    • Anti-viral Drugs
    • Anti-bacterial Drugs
    • Anti-fungal Drugs
    • Others
    • Cardiovascular Drugs
    • Anti-inflammatory Drugs
    • Analgesics Drugs
    • Anti-diabetics
    • Ophthalmic Drugs
    • Neurological Drugs
  12. Global Market Analysis 2020 to 2024 and Forecast 2025 to 2035, By End Users
    • Pharmaceutical & Biotechnology Companies
    • Contract Manufacturing Organizations (CMO)
    • Contract Research Organizations (CRO)
    • Academic & Research Institutes
  13. Global Market Analysis 2020 to 2024 and Forecast 2025 to 2035, By Region
    • North America
    • Latin America
    • East Asia
    • South Asia & Pacific
    • Eastern Europe
    • Western Europe
    • Middle East & Africa
  14. North America Sales Analysis 2020 to 2024 and Forecast 2025 to 2035, by Key Segments and Countries
  15. Latin America Sales Analysis 2020 to 2024 and Forecast 2025 to 2035, by Key Segments and Countries
  16. East Asia Sales Analysis 2020 to 2024 and Forecast 2025 to 2035, by Key Segments and Countries
  17. South Asia & Pacific Sales Analysis 2020 to 2024 and Forecast 2025 to 2035, by Key Segments and Countries
  18. Eastern Europe Sales Analysis 2020 to 2024 and Forecast 2025 to 2035, by Key Segments and Countries
  19. Western Europe Sales Analysis 2020 to 2024 and Forecast 2025 to 2035, by Key Segments and Countries
  20. Middle East & Africa Sales Analysis 2020 to 2024 and Forecast 2025 to 2035, by Key Segments and Countries
  21. Sales Forecast 2025 to 2035 by Product Type, Functionality, Material Type, Availability, Drug Modality, Therapeutic Class, and End Users for 30 Countries
  22. Competition Outlook, including Market Structure Analysis, Company Share Analysis by Key Players, and Competition Dashboard
  23. Company Profile
    • Berry Global Inc.
    • Amcor Plc
    • Aptar, Inc.
    • Closure Systems International, Inc.
    • O.Berk Company, LLC
    • Bericap GmbH and Co KG
    • UNITED CAPS
    • CL Smith Company
    • Georg MENSHEN GmbH & Co. KG
    • WestRock Company

Key Segments

By Product Type:

  • Screw Caps & Closure
  • Snap Caps & Closure
  • Push-Pull Caps & Closure
  • Stopper & Seals
  • Others

By Functionality:

  • Child Resistant
  • Tamper-evident

By Material type:

  • Plastic
  • Elastomer
  • Metal

By Availability:

  • Prescription (Rx) Pharmaceuticals
  • Over-the-Counter (OTC) Pharmaceuticals

By Drug Modality:

  • Small Molecule (Synthetic Drugs)
  • Biopharmaceuticals

By Therapeutic class:

  • Anticancer Drugs
  • Anti-infective Drugs
  • Anti-viral Drugs
  • Anti-bacterial Drugs
  • Anti-fungal Drugs
  • Others
  • Cardiovascular Drugs
  • Anti-inflammatory Drugs
  • Analgesics Drugs
  • Anti-diabetics
  • Ophthalmic Drugs
  • Neurological Drugs
  • Others

By End Users:

  • Pharmaceutical & Biotechnology Companies
  • Contract Manufacturing Organizations (CMO)
  • Contract Research Organizations (CRO)
  • Academic & Research Institutes

By Region:

  • North America
  • Latin America
  • East Asia
  • South Asia & Pacific
  • Eastern Europe
  • Western Europe
  • Middle East & Africa

Explore Healthcare Insights

Protein Diagnostics Market

Protein Diagnostics Market Share, Size and Forecast 2025 to 2035

CGRP Inhibitors Market

CGRP Inhibitors Market Trends - Growth, Demand & Forecast 2025 to 2035

Indolent Systemic Mastocytosis treatment Market

Indolent Systemic Mastocytosis treatment Market Insights: Size, Trends & Forecast 2025 to 2035

Intraoperative Fluorescence Imaging Market

Intraoperative Fluorescence Imaging Market Report - Demand, Trends & Industry Forecast 2025 to 2035

Lung Cancer PCR Panel Market

Lung Cancer PCR Panel Market Trends, Growth, Demand & Forecast 2025 to 2035

Polymyxin Resistance Testing Market

Polymyxin Resistance Testing Market Trends – Innovations & Growth 2025 to 2035

Future Market Insights

Pharmaceutical Caps and Closures Market