The global peptide therapeutics market is valued at USD 38.0 Billion for 2023 and is expected to reach USD 106.0 Billion by 2033, expanding at an impressive CAGR of 10.8% over the period of 2023 to 2033.
Peptide therapeutics currently account for a 53.7% share of the global drug discovery market, with the Asia Pacific market advancing rapidly in peptide-based drugs. For more than a century, peptide medicines have been used to treat metabolic illnesses. In comparison to tiny chemical compounds, peptide drugs offer numerous advantages, resulting in huge demand across geographies.
| Attributes | Details |
|---|---|
| Market CAGR for Peptide Therapeutics (2023 to 2033) | 10.8% |
| Market Size for Peptide Therapeutics (2023) | USD 38.0 Billion |
| Market Size for Peptide Therapeutics (2033) | USD 106.0 Billion |
| Global Market Absolute Dollar Growth (USD Million/Billion) | USD 68.0 Billion |
The comparative analysis and market growth rate of the global market for peptide therapeutics, as studied by Future Market Insights, Inc may show a negative BPS growth in the H1-2023 outlook as compared to H1-2023 projected period by 20 BPS, and a negative BPS dip is expected in H1-2023 over H1- 2021 duration with 56 Basis Point Share (BPS).
The dip in the BPS values observed is due to the high-cost factors associated with manufacturing a peptide, as well as the limitation of the molecule having a short half-life, therefore incurring high research expenditures. However, with a wide range of targets available for peptides, manufacturers have opportunities to develop novel peptide therapeutic formulations, thus impacting the overall market positively.
The market is subject to changes in lieu of factors such as research funding and grants and outsourcing of manufacturing capabilities in accordance with the macro and industry standards. Conversely, advancements in next-generation therapeutics and peptide-based targeted drug delivery for cancer cells may aid in the positive growth traction of the overall market.
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The peptide therapeutics market expanded at a CAGR of 10% from 2014 to 2021.
Peptide therapeutic companies have come to appreciate the role that peptide pharmaceuticals can play in addressing unmet medical needs and how this class of compounds can be an excellent complement or even a preferable alternative to small molecule and biological therapeutics, resulting in a revival of interest and scientific momentum in peptide drug discovery over the last decade.
The market is being driven by the rising prevalence of cancer and metabolic disorders, increased investments in the research & development of innovative medications, and technological developments in peptide therapies.
Peptide pharmaceuticals have developed a wide range of applications in medicine and biotechnology during the last decade, and therapeutic peptide research is undergoing a revival for commercial reasons. Peptide drug discovery has a significant role in the healthcare sector. LupronTM, a peptide medication from Abbott Laboratories, is used to treat prostate cancer and other conditions.
Chronic diseases such as cancer, cardiovascular disease, and diabetes are the major causes of death and disability worldwide, according to the World Health Organization (WHO). As a result, the rising prevalence of chronic diseases is driving demand for effective medicines, which is likely to propel the peptide therapeutics market forward.
Peptide therapeutics demand is predicted to surge at a CAGR of 10.8% from 2023 to 2033, with the global market expected to close in on a valuation of USD 106 Billion by 2033.
Oral Peptide-based Drugs Becoming a Hit
Due to a decrease in non-peptide chemical medications accessible in the market, sales of peptide therapeutic companies are currently rising. The peptides generics market is expected to develop as the patent cliff rises.
Because pharma businesses are shifting their focus to better potential in the peptide therapies sector, CMOs that provide end-to-end services to biotech and pharmaceutical companies are rising.
As peptides are a common component of food, both the stomach and intestines contain a plethora of enzymes that can break them down, and most peptide-based drugs do not survive the gastrointestinal tract.
Heinis's Group is currently using a novel technology to develop oral peptide drugs that act directly on gastrointestinal targets, bypassing the bloodstream. Oral peptide drugs may play a crucial role in the treatment of a wide range of disorders.
Increasing Use of Peptides in Cancer & Diabetes Treatment
Peptides were originally used solely for diagnostics and hormone therapy; however, with technological advancements, they are now widely used for the treatment of cancer and chronic metabolic illnesses as well.
Chemotherapy, which is the most common kind of cancer treatment, is beset by problems due to its inability to deliver the right amount of medicine to the right place at the right time. It also affects the body's natural cells. The use of peptide-based therapeutics in cancer treatment has opened up a promising new channel for the peptide therapeutics market's future growth.
Apart from that, peptide therapies are widely utilized in injections for diabetic patients, thanks to the emergence of novel synthetic techniques that reduce injection frequency while also improving stability and other physical features.
This is influencing the usage of peptide therapies over oral drugs, which coincides with the rising incidence of diabetes and the growing preference for rapid and accurate treatment techniques.
Rising Popularity of Peptide-based Therapeutics in Cosmeceuticals
Peptides are also employed in cosmeceutical operations to slow down the aging process of the skin. This, combined with people's growing awareness of their physical appearance and a desire to keep their skin looking young and healthy, is fuelling global acceptance of cosmetic operations and peptide-based therapeutics.
Furthermore, the need for multifunctional peptide-based drug materials is being fuelled by the growing trend of tailored and targeted treatments. This, together with increased investments in the development of new peptide therapies for the treatment of autoimmune and inflammatory illnesses, is expected to boost market growth.
Principal Consultant
| Attributes | Details |
|---|---|
| Top Route Of Administration | Parenteral Route |
| CAGR % 2017 to 2022 | 10.3% |
| CAGR % 2023 to End of Forecast(2033) | 10.8% |
Parenteral Route Highly Preferred for Peptide Drug Delivery
The parenteral route provides improved bioavailability, faster onset of action, and superior clinical results, making it the preferred option for peptide therapeutic drug delivery. The highest market share for peptide therapeutics, 70.7%, is accounted for by the parenteral route of administration of peptide medicines.
Currently, the majority of peptide medications are delivered via the parenteral route. Alternative administration modes, including oral, intranasal, and transdermal delivery routes, are gaining momentum as technology advances.
The parenteral method, on the other hand, has the potential for side effects and necessitates the use of specialized personnel for delivery. As a result, market participants are turning to alternative administration methods, such as the oral route, which causes less pain and eliminates the need for outside assistance.
Adoption of various delivery forms could also allow peptide medicines to be used more widely in other disease areas, such as inflammation, where topical peptide administration could be the foundation for extremely effective new treatments.
| Attributes | Details |
|---|---|
| Top Application Type | Cancer |
| CAGR % 2017 to 2022 | 10.2% |
| CAGR % 2023 to End of Forecast (2033) | 10.6% |
A Rise in Patients with Cancer and Other Chronic Conditions May Promote the Cancer Segment.
The cancer category led the global market in 20213 in terms of application. The top cause of death in the world is cancer. The World Health Organization estimates that cancer may be responsible for roughly 10 million deaths worldwide in 2020.
Chemotherapy, the main form of cancer treatment, faces significant difficulties because it can't administer the right dosage of medication directly, severely affecting the body's normal cells.
As therapeutic peptides may deliver drugs with precise binding sites, their use in the treatment of cancer has created a viable channel for the future expansion of the global peptide therapeutics market.
Over the last few years, peptide-based therapeutic vaccines have gained recognition as one of the most successful treatments for tumor immunotherapy. Due to the growth in the geriatric population, the prevalence and incidence rate of other chronic problems such as Alzheimer's, diabetes, heart diseases, and immunological disorders are expected to drive the global peptide and Alzheimer's peptide therapies markets in the coming years.
High Government Investments in R&D of Peptide Medications Fuelling Market Growth in North America
The global market for peptide therapeutics has been studied across North America, Latin America, Europe, East Asia, South Asia & Pacific, and the Middle East & Africa (MEA).
Throughout the projected period, North America is expected to lead the global market. This regional market is prominent as a result of factors such as increased awareness of peptide treatments. The growing need for diagnostics in cancer and other diseases and the expanding biotechnology industry.
Increased government and industry spending on research and development is also predicted to help peptide therapies maintain their dominance over the coming years. In this region, a well-established biopharmaceutical and pharmaceutical industry is a primary driver for market growth.
The peptide therapeutics markets in Western Europe and Eastern Europe are expected to be driven by the rising popularity of peptide therapeutics treatment procedures, increasing medical research & development, etc.
The Latin American market for peptide therapeutics is expected to account for steady market growth.
The Asia Pacific market for peptide therapeutics is predicted to expand at a high CAGR throughout the forecast period, making it a highly viable market. This is due to a large patient pool, rising healthcare expenditure, and an increasing need for innovative and advanced therapies.
The MEA market for peptide therapeutics is expected to progress at a slightly slower rate than other regions but is expected to pick up pace towards the end of the projection period.
| Country | United States |
|---|---|
| HCAGR (2017 to 2022) | 10.5% |
| CAGR (2023 to 2033) | 11% |
| Country | United Kingdom |
|---|---|
| HCAGR (2017 to 2022) | 9.3% |
| CAGR (2023 to 2033) | 9.8% |
| Country | Germany |
|---|---|
| HCAGR (2017 to 2022) | 94% |
| CAGR (2023 to 2033) | 9.9% |
| Country | China |
|---|---|
| HCAGR (2017 to 2022) | 10.6% |
| CAGR (2023 to 2033) | 11.1% |
| Country | India |
|---|---|
| HCAGR (2017 to 2022) | 11.3% |
| CAGR (2023 to 2033) | 11.7% |
| Attributes | Details |
|---|---|
| United States Market Size (USD Million/Billion) by End of Forecast Period(2033) | USD 41.1 Billion |
| United States Market Absolute Dollar Growth (USD Million/Billion) | USD 26.7 Billion |
High Incidence of Cancer Driving Demand for Peptide-based Therapeutics
According to the American Cancer Society's forecasts, a little more than 1.9 Million new cancer cases are predicted to be diagnosed in the United States in 2022. Cancer is the 2nd leading cause of death in the United States, trailing only heart disease.
This data suggests that peptides may become more relevant in the United States healthcare industry and that peptides may progress through clinical trials. Demand for peptide therapies is predicted to rise as cancer becomes more prevalent.
Due to factors such as an increase in the number of research programs in the medical business as well as an increase in the number of diseases in the country, the United States has the biggest market share.
| Attributes | Details |
|---|---|
| United Kingdom Market Size (USD Million/Billion) by End of Forecast Period(2033) | USD 3.4 Billion |
| United Kingdom Market Absolute Dollar Growth (USD Million/Billion) | USD 2.1 Billion |
Throughout the anticipated period, the United Kingdom market for peptide therapeutics is expected to expand at a strong CAGR of 9.8%. Earlier, from 2017 to 2022, the market in the United Kingdom grew at a solid CAGR of 9.8%.
The expansion of the peptide therapeutics market in the United Kingdom is anticipated to be aided by rising awareness of the applications of peptides for the treatment of various chronic disorders. The United Kingdom peptide therapeutics markets are anticipated to be driven by factors such as the growing demand for peptide therapeutics treatments, increased medical research, and development, etc.
| Attributes | Details |
|---|---|
| Germany Market Size (USD Million/Billion) by End of Forecast Period(2033) | USD 5.7 Billion |
| Germany Market Absolute Dollar Growth (USD Million/Billion) | USD 3.5 Billion |
The German market is estimated to grow at a solid CAGR of 9.9% over the forecast period. Prior to that, the German market expanded at a respectable HCAGR of 9.4% from 2017 to 2022.
The expansion of the peptide therapeutics market in the region is being aided by the region's well-developed healthcare infrastructure, expensive peptide therapeutics medications, and advantageous reimbursement regulations. The generic market is expected to increase rapidly in the near future as a result of decreasing raw material costs and the patent expiration of popular medications.
| Attributes | Details |
|---|---|
| India Market Size (USD Million/Billion) by End of Forecast Period(2033) | USD 1.7 Billion |
| India Market Absolute Dollar Growth (USD Million/Billion) | USD 1.1 Billion |
The Indian peptide therapeutics market is predicted to grow at a healthy rate over the coming years. Increased frequency of chronic diseases, increasing aging population, and rising healthcare costs are all contributing to market expansion in the country.
In terms of the number of cancer cases, India is ranked third among all nations. According to the National Cancer Registry Programme report, over 1,300,000 people in India are diagnosed with cancer each year. This surge is attributed to unhealthy lifestyles, increased urban pollution, cigarette and alcohol consumption, and a rise in obesity.
According to the Indian Council of Medical Research (ICMR), cancer cases in India may climb 12% in the next five years. Breast cancer, cervical cancer, and oral cancer are the most common types of cancer among Indians.
Synthetic peptide drugs can be made to look like naturally occurring peptides and can be used to treat cancer and other serious illnesses. Hemmo has been supplying peptide products and custom peptide synthesis for more than 38 years, making it one of India's major makers of synthetic peptide drugs provider.
Leading market players are huge and well-established, with a high level of brand loyalty. Major peptide therapeutics medication manufacturers in India are Emcure Pharmaceutical Pvt. Ltd., Cipla Ltd., Gland Pharma Limited, Troikaa Pharmaceuticals Ltd., and Biological E Limited (IN).
| Attributes | Details |
|---|---|
| China Market Size (USD Million/Billion) by End of Forecast Period(2033) | USD 4.7 Billion |
| China Market Absolute Dollar Growth (USD Million/Billion) | USD 3.1 Billion |
Due to an increase in the number of elderly people, the expansion of healthcare infrastructure, and an increase in investment projects in the region, China is expected to experience significant growth. Due to the rising frequency of infectious diseases in the region, the market in China is predicted to expand at a rapid CAGR of 11.1% over the course of the projected period.
The market in China is being driven by an increase in the number of elderly people and a rise in healthcare spending. The China peptide therapeutics market is also expected to benefit from a huge patient base and strong demand for more advanced treatments.
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There are several significant participants in the moderately competitive peptide therapies industry. For the international expansion of their product portfolios, the leading players are engaged in strategic alliances such as acquisitions and collaborations, coupled with research efforts.
Leading suppliers of peptide therapeutics are concentrating on market expansion through distribution contracts, joint ventures, and white space investigation. Additionally, established businesses are collaborating with regional firms to improve their area presence and boost their manufacturing capabilities.
Recent Development:
| Date | December 2020 |
|---|---|
| Company | ONL Therapeutics, Inc. |
| Details | In a Series B financing round that was held in December 2020, ONL Therapeutics, Inc., a biopharmaceutical business with headquarters in Michigan that creates innovative medicines, secured USD 46.9 Million. With the help of this grant, peptide manufacturing would be developed in order to get ready for an IND filing for phase 2 research. |
| Date | June 2022 |
|---|---|
| Company | Ariceum Therapeutics |
| Details | Ariceum Therapeutics, a private biotech company creating a radiopharmaceutical product, received USD 25 million in a second round of funding from EQT Life Sciences in June 2022. Ariceum's lead asset and proprietary peptide derivative, satoreotide, would be developed thanks to the funding. |
| Date | May 2022 |
|---|---|
| Company | Biohaven Pharmaceutical Holding Company Ltd. |
| Details | The developer of NURTEC ODT, an advanced dual-acting migraine medicine approved for both acute treatments and episodic migraine prevention in adults, Biohaven Pharmaceutical Holding Company Ltd. and Pfizer Inc. announced a new collaboration in May 2022. |
| Date | February 2022 |
|---|---|
| Company | Amgen |
| Details | Amgen and Plexium, Inc. announced a multi-year research collaboration and license agreement in February 2022 to develop new targeted protein degradation treatments for hitherto difficult pharmacological targets. By using Amgen's experience in generating multispecific compounds, the multiyear collaboration may aid in the development of new molecular glue therapies. |
| Date | May 2022 |
|---|---|
| Company | Bristol Myers Squibb |
| Details | Bristol Myers Squibb and LOTTE Corporation announced in MAY 2022 that LOTTE had made the decision to purchase Bristol Myers Squibb's production facility in East Syracuse, New York. The US operations of LOTTE's new biologics CDMO may be located in East Syracuse. |
| Date | May 2021 |
|---|---|
| Company | ISSAR Pharmaceuticals |
| Details | ISSAR Pharmaceuticals planned in May 2021 to license out its peptide-based unique chemical entities with a pre-IND file and a United States Patent for various neglected healthcare demands of the people, seeking to make it accessible and inexpensive for improved outcomes. |
High incidence of cancer-driving demand witnessed higher growth.
The market is estimated to secure a valuation of USD 38 billion in 2023.
The market is forecast to register a CAGR of 10.8% through 2033.
The cancer category led the global market in terms of application.
An increase in patient knowledge is a prominent trend in the market.
1. Executive Summary 2. Market Overview 3. Market Background 4. Global Market Analysis 2017 to 2022 and Forecast, 2023 to 2033 5. Global Market Analysis 2017 to 2022 and Forecast 2023 to 2033, By Application Type 5.1. Cancer 5.2. Cardiovascular 5.3. Central Nervous Systems 5.4. Metabolic Disorders 5.5. Infection 5.6. Hematological Disorders 5.7. Gastrointestinal Disorders 5.8. Dermatology 5.9. Respiratory Disorders 5.10. Acromegaly 5.11. Other Application Types 6. Global Market Analysis 2017 to 2022 and Forecast 2023 to 2033, By Route Of Administration 6.1. Parenteral Route 6.2. Mucosal Route 6.3. Oral Route 6.4. Transdermal Route 7. Global Market Analysis 2017 to 2022 and Forecast 2023 to 2033, By Drug Type 7.1. Branded 7.2. Generic 8. Global Market Analysis 2017 to 2022 and Forecast 2023 to 2033, By Region 8.1. North America 8.2. Latin America 8.3. Western Europe 8.4. Eastern Europe 8.5. Asia Pacific excluding Japan (APEJ) 8.6. Japan 8.7. Middle East and Africa (MEA) 9. North America Market Analysis 2017 to 2022 and Forecast 2023 to 2033, By Country 10. Latin America Market Analysis 2017 to 2022 and Forecast 2023 to 2033, By Country 11. Western Europe Market Analysis 2017 to 2022 and Forecast 2023 to 2033, By Country 12. Eastern Europe Market Analysis 2017 to 2022 and Forecast 2023 to 2033, By Country 13. APEJ Market Analysis 2017 to 2022 and Forecast 2023 to 2033, By Country 14. Japan Market Analysis 2017 to 2022 and Forecast 2023 to 2033, By Country 15. MEA Market Analysis 2017 to 2022 and Forecast 2023 to 2033, By Country 16. Key Countries Market Analysis 17. Market Structure Analysis 18. Competition Analysis 18.1. Eli Lilly and Company 18.2. AstraZeneca plc 18.3. Merck & Co. Inc 18.4. Ipsen S.A 18.5. Novo Nordisk A/S 18.6. Teva Pharmaceutical Industries Ltd. 18.7. Amgen, Inc. 18.8. Bachem Holding AG 18.9. Novartis AG 18.10. Pfizer, Inc. 19. Assumptions & Acronyms Used 20. Research Methodology
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Peptide Therapeutics Market
