Orthobiologics Market Outlook (2023 to 2033)

The orthobiologics market is anticipated to expand its boundaries at a CAGR of 3.0% during the forecast period. The market holds a share of US$ 6.0 billion in 2023, while it is expected to cross a value of US$ 8.1 billion by 2033.

The orthobiologics market outlook states that the increased healthcare budget is pushing the adoption of advanced healthcare equipment with advancing technology. Furthermore, bone-related disorders & injuries are propelling the growth of the orthobiologics market. The increase in the overall patient tally is likely to impact the market positively. The increased application of viscosupplements for delaying knee replacement and surgeries is also pushing healthcare facilities to adopt orthobiologics products. Along with this, the long physical pain is also pushing end users to adopt technologies that prevent and delay painful surgeries. The rising amount of product introductions is likely to impact the sales of orthobiologics products. Increasing accidents in urban spaces are leading to higher bone disorders and fractures, leading to the adoption of orthobiologics in the healthcare systems.

The advanced integration systems with research and development extensions are creating exciting future opportunities for biological substances that are healing musculoskeletal injuries quickly. The products include bone allograftchevron, soft tissue allograftchevron, and cartilage allograftchevron. Though, orthopedic biologic products work as an optimum treatment solution for knee and shoulder injuries.

Attributes Details
Orthobiologics Market CAGR (2023 to 2033) 3.0%
Orthobiologics Market Size (2023) US$ 6.0 billion
Orthobiologics Market Size (2033) US$ 8.1 billion

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How is the Future Outlook for Orthobiologics Market in Comparison to the Historical Pattern?

Short-term Growth: Growing research and development programs in bone and joints are expected to thrive in the market during the period. This also enhanced the company's engagement in orthobiologics and its product.

Mid-term Growth: Increasing geriatric population with age-related dysfunction to the bone-related system is expected to drive the market growth, as elderly people are more prone to fragility fractures and the incidents of fracture are more likely to increase by 10 to 15 times.

Long-term Growth: Growth is expected in the future for orthobiologics as their acceptance as an alternative treatment of orthopedic issues, and bone-related surgeries gain traction. Furthermore, advanced orthobiologics products are penetrating households with people suffering from long-term orthopedic pain. The restoring orthobiologics market is expected to flourish at a CAGR of 3% between 2023 and 2033.

Higher Number of Accidents and Advanced Orthopedic Procedures are Favoring Orthobiologics Market Growth

The increasing geriatric population offers surplus opportunities for the manufacturers of orthobiologics. The crucial root of amputations is diseases related to aging as osteoarthritis, musculoskeletal diseases, spine deformity, etc. Increased incidence of accidents owing to increasing urbanization is also a key factor expected to create numerous opportunities for orthobiologics manufacturers. Elevating surgical procedures also presents growth opportunities for the market.

The increased incidences of trauma cases, lifestyle-related diseases, and other chronic disorders have led to a rise in numerous orthopaedic surgeries at a global level. This growing trend is anticipated to increase the sales of orthobiologics products in the present and forthcoming years.

The emergence of online sales channels and government initiatives bot are contributing to the growth of the market. Manufacturers are focused on creating sales directly through their company’s website to target more customers without the interference of third-party distributors. This enables the manufacturers to eliminate the variation in product pricing owing to the involvement of third-party suppliers.

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Orthobiologics Market Country-wise Insights

Regions Absolute Market Growth
United States US$ 749.0 million
United Kingdom US$ 73.3 million
China US$ 61.2 million
Japan US$ 179.5 million
India US$ 13.6 million

Which Region leads the Market in terms of Market Share?

The United States spends High Capital on Orthopedic Enhancements and Future Solutions.

Region Attributes
United States Market CAGR (2023 to 2033) 3.2%
United States Market Absolute Doller Growth (US$ million/billion) US$ 749.0 million

The United States leads the orthobiologics market in terms of market share, as it is expected to hold a value of US$ 2.8 billion by 2033. Increased healthcare budget, rising per capita income, and advancements in the field of orthopedics are expected to accelerate market growth. The citizens are more likely to choose the alternative treatment than go through surgery. The United States spinal implants and orthobiologics portfolio showcases the positive result of the substitute products and how they help the end user in relieving pain. The region is expected to thrive at a CAGR of 3.2% through 2033.

How does the United Kingdom Perform in the Global Orthobiologics Market?

Latest Innovative Products have Transformed the Future of the Global Orthobiologics Market

Region Attributes
United Kingdom Market CAGR (2023 to 2033) 2.5%
United Kingdom Market Absolute Doller Growth (US$ million/billion) US$ 73.3 million

The United Kingdom increased its healthcare audits along with the soaring frequency of accidents and the geriatric population. These efforts are likely to help the industry boom. Furthermore, the advanced diagnosis and treatment procedures push the United Kingdom market with an expected value of US$ 339.9 million by 2033. The rising awareness of alternative orthopedic treatment fuels the demand for orthobiologics products. The nation is likely to expand at a CAGR of 2.5% through 2033.

How will the Orthobiologics Market Expand Across India?

Region Attributes
Indian Market CAGR (2023 to 2033) 6.6%
Indian Market Absolute Doller Growth (US$ million/billion) US$ 13.6 million

India is constantly building their healthcare sector along with the adoption of advanced orthobiologic products. Furthermore, the integration of regenerative medicines of orthobiologics with platelet-rich plasma therapy is making India the leading market in terms of CAGR. The thriving Indian market is an outcome of the fusion and the belief system of patients that stick with regenerative medicine and alternative treatment. The market is expected to flourish at a CAGR of 6.6% between 2023 to 2033.

Category-wise Insights

Segment Top Product Type
Top Sub-segment Bone Graft Substitute
CAGR (2017 to 2022) 2.9%
CAGR (2023 to 2033) 3.5%
Segment Top End User
Top Sub-segment Hospitals
CAGR (2017 to 2022) 8.5%
CAGR (2023 to 2033) 9.1%

Higher Impacts on the Bones due to Fatal Accidents are Propelling the Segment Growth

The bone graft substitute segment in the product type category is expected to dominate the global market in the forecast period. This segment has been a lucrative one since 2012. During the 2012 to 2016 timeline, the bone graft substitute segment reflected high growth opportunities and led the global market. This trend is observed in the current market scenario and is expected to continue over the period of assessment. In 2017, the bone graft substitute segment reached a value of US$ 2,521.6 million, and according to the growth trend exhibited by this segment, it is estimated to reach a market valuation of above US$ 3 billion by the end of 2027. During the forecast period from 2023 to 2033, it is poised to reflect a CAGR of 3.5%. However, the segment flourished at a CAGR of 2.9% between 2017 and 2022.

The bone graft substitute segment is further analyzed and divided into allograft, xenograft, synthetic, and bone morphogenetic protein sub-segments. This is the second leading segment in terms of market value. Allograft and synthetic sub-segments have a notable yet almost equal contribution to the revenue of the parent segment.

The allograft sub-segment reached a valuation of US$ 937.5 million by 2022, leading other sub-segments. However, the synthetic subcategory is poised to grow at a relatively higher rate than allografts in the coming years.

Hospitals with Advanced Orthobiologic Products Become the First Emergency Destination

Based on end users, the hospital segment thrives at a CAGR of 9.1% during the forecast period. This growth is attributed to the expansion of hospitals as governments focus more on infrastructure. The higher space and capacity to implement and use orthobiologic products also fuels their consumption of them in hospitals.

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Competition Scenario

The market players are focusing on creating advanced products that provide ease to patients. The research and development programs that deliver products to support the patient in their overall recovery process are another factor competitors focus on. This involves the integration of regenerative medicine, alternative therapies, and bone support products.

Latest Developments:

  • Medtronic extends the product list with balloon kyphoplasty, tumor management, vertebroplasty, sports surgery, nucleus removal tools, and SpineLine reimbursement. These extensions are helping the hospital facilities along with the introduction of electrosurgical products.
  • In 2023, Zimmer Biomet acquired embody, an orthobiologics company for US$ 155 million. The company focuses on soft tissue healing and enhanced pipeline area. The acquisition will enhance the supply chain and distribution channel.

Key Contributors of the Orthobiologics Market are

  • Medtronic (Ireland)
  • Zimmer Biomet
  • DePuy Synthes (Johnson & Johnson Services, Inc.)
  • Stryker
  • Anika Therapeutics, Inc.
  • SeaSpine
  • Bioventus
  • RTI Surgical
  • MTF Biologics
  • Arthrex, Inc.
  • Smith & Nephew

Scope of Report

Attribute Details
Market Size Value in 2023 US$ 6 billion
Market Size Value in End of Forecast (2033) US$ 8.1 billion
Market Analysis US$ billion for Value
Key Region Covered North America; Latin America; Europe; Asia Pacific; Middle East & Africa (MEA); Others
Key Segments By Product Type, By End User, By Region
Key Companies Profiled Medtronic (Ireland); Zimmer Biomet; DePuy Synthes (Johnson & Johnson Services, Inc.); Stryker; Anika Therapeutics, Inc.; SeaSpine; Bioventus; RTI Surgical; MTF Biologics; Arthrex, Inc.; Smith & Nephew
Report Coverage Market Forecast, Company Share Analysis, Competition Intelligence, DROT Analysis, Market Dynamics and Challenges, and Strategic Growth Initiatives
Customization & Pricing Available upon Request

Key Segments

By Product Type:

  • Bone Growth Stimulators (BGS)
    • Non-invasive Electrical BGS
    • Invasive Electrical BGS
    • Ultrasound BGS
  • Viscosupplements
    • Single Injection Viscosupplements
    • Three Injection Viscosupplements
    • Five Injection Viscosupplements
  • Bone Graft Substitute
    • Allografts
    • Synthetics
    • Xenografts
    • Bone Morphogenetic Protein

By End User:

  • Hospitals
  • Ambulatory Surgical Centres
  • Orthopaedics Clinics

By Region:

  • North America
  • Latin America
  • Europe
  • Asia Pacific (APAC)
  • Middle East & Africa (MEA)

Frequently Asked Questions

How Big is the Orthobiologics Market?

The market is valued at US$ 6.0 billion in 2023.

Who are the Top Orthobiologics Market Players?

Panasonic, Vishay, and Silicon Labs are top market players.

Which Industry is the Key Consumer of the Orthobiologics Market?

The pharmaceutical industry is the primary consumer of the orthobiologics market.

How Big will the Orthobiologics Market by 2033?

The market is estimated to reach US$ 8.1 billion by 2033.

How the Market is Expected to Expand in the Future?

The market trend for orthobiologics is expected to record a CAGR of 3.0% by 2033.

Table of Content

1. Executive Summary | Orthobiologics Market

    1.1. Global Market Outlook

    1.2. Demand-side Trends

    1.3. Supply-side Trends

    1.4. Technology Roadmap Analysis

    1.5. Analysis and Recommendations

2. Market Overview

    2.1. Market Coverage / Taxonomy

    2.2. Market Definition / Scope / Limitations

3. Market Background

    3.1. Market Dynamics

        3.1.1. Drivers

        3.1.2. Restraints

        3.1.3. Opportunity

        3.1.4. Trends

    3.2. Scenario Forecast

        3.2.1. Demand in Optimistic Scenario

        3.2.2. Demand in Likely Scenario

        3.2.3. Demand in Conservative Scenario

    3.3. Opportunity Map Analysis

    3.4. Investment Feasibility Matrix

    3.5. PESTLE and Porter’s Analysis

    3.6. Regulatory Landscape

        3.6.1. By Key Regions

        3.6.2. By Key Countries

    3.7. Regional Parent Market Outlook

4. Global Market Analysis 2017 to 2022 and Forecast, 2023 to 2033

    4.1. Historical Market Size Value (US$ Million) Analysis, 2017 to 2022

    4.2. Current and Future Market Size Value (US$ million) Projections, 2023 to 2033

        4.2.1. Y-o-Y Growth Trend Analysis

        4.2.2. Absolute $ Opportunity Analysis

5. Global Market Analysis 2017 to 2022 and Forecast 2023 to 2033, By Product Type

    5.1. Introduction / Key Findings

    5.2. Historical Market Size Value (US$ Million) Analysis By Product Type, 2017 to 2022

    5.3. Current and Future Market Size Value (US$ Million) Analysis and Forecast By Product Type, 2023 to 2033

        5.3.1. Bone Growth Stimulators

            5.3.1.1. Non-Invasive

            5.3.1.2. Invasive

            5.3.1.3. Ultrasound

        5.3.2. Viscosupplements

            5.3.2.1. One Injection

            5.3.2.2. Three Injection

            5.3.2.3. Five Injection

        5.3.3. Bone Graft Substitute

            5.3.3.1. Allografts

            5.3.3.2. Synthetics

            5.3.3.3. Xenografts

            5.3.3.4. BMP

    5.4. Y-o-Y Growth Trend Analysis By Product Type, 2017 to 2022

    5.5. Absolute $ Opportunity Analysis By Product Type, 2023 to 2033

6. Global Market Analysis 2017 to 2022 and Forecast 2023 to 2033, By End User

    6.1. Introduction / Key Findings

    6.2. Historical Market Size Value (US$ Million) Analysis By End User, 2017 to 2022

    6.3. Current and Future Market Size Value (US$ Million) Analysis and Forecast By End User, 2023 to 2033

        6.3.1. Hospitals

        6.3.2. Ambulatory Surgical Centers

        6.3.3. Orthopedic Clinics

    6.4. Y-o-Y Growth Trend Analysis By End User, 2017 to 2022

    6.5. Absolute $ Opportunity Analysis By End User, 2023 to 2033

7. Global Market Analysis 2017 to 2022 and Forecast 2023 to 2033, By Region

    7.1. Introduction

    7.2. Historical Market Size Value (US$ Million) Analysis By Region, 2017 to 2022

    7.3. Current Market Size Value (US$ Million) Analysis and Forecast By Region, 2023 to 2033

        7.3.1. North America

        7.3.2. Latin America

        7.3.3. Europe

        7.3.4. Asia Pacific excluding Japan

        7.3.5. Japan

        7.3.6. MIDDLE EAST AND AFRICA

    7.4. Market Attractiveness Analysis By Region

8. North America Market Analysis 2017 to 2022 and Forecast 2023 to 2033, By Country

    8.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2017 to 2022

    8.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033

        8.2.1. By Country

            8.2.1.1. USA

            8.2.1.2. Canada

        8.2.2. By Product Type

        8.2.3. By End User

    8.3. Market Attractiveness Analysis

        8.3.1. By Country

        8.3.2. By Product Type

        8.3.3. By End User

    8.4. Key Takeaways

9. Latin America Market Analysis 2017 to 2022 and Forecast 2023 to 2033, By Country

    9.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2017 to 2022

    9.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033

        9.2.1. By Country

            9.2.1.1. Brazil

            9.2.1.2. Mexico

            9.2.1.3. Rest of Latin America

        9.2.2. By Product Type

        9.2.3. By End User

    9.3. Market Attractiveness Analysis

        9.3.1. By Country

        9.3.2. By Product Type

        9.3.3. By End User

    9.4. Key Takeaways

10. Europe Market Analysis 2017 to 2022 and Forecast 2023 to 2033, By Country

    10.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2017 to 2022

    10.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033

        10.2.1. By Country

            10.2.1.1. Germany

            10.2.1.2. UK

            10.2.1.3. France

            10.2.1.4. Spain

            10.2.1.5. Italy

            10.2.1.6. Rest of Europe

        10.2.2. By Product Type

        10.2.3. By End User

    10.3. Market Attractiveness Analysis

        10.3.1. By Country

        10.3.2. By Product Type

        10.3.3. By End User

    10.4. Key Takeaways

11. Asia Pacific excluding Japan Market Analysis 2017 to 2022 and Forecast 2023 to 2033, By Country

    11.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2017 to 2022

    11.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033

        11.2.1. By Country

            11.2.1.1. China

            11.2.1.2. India

            11.2.1.3. Australia & New Zealand

            11.2.1.4. Association of Southeast Asian Nations

            11.2.1.5. Rest of Asia Pacific excluding Japan

        11.2.2. By Product Type

        11.2.3. By End User

    11.3. Market Attractiveness Analysis

        11.3.1. By Country

        11.3.2. By Product Type

        11.3.3. By End User

    11.4. Key Takeaways

12. Japan Market Analysis 2017 to 2022 and Forecast 2023 to 2033, By Country

    12.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2017 to 2022

    12.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033

        12.2.1. By Country

        12.2.2. By Product Type

        12.2.3. By End User

    12.3. Market Attractiveness Analysis

        12.3.1. By Country

        12.3.2. By Product Type

        12.3.3. By End User

    12.4. Key Takeaways

13. MIDDLE EAST AND AFRICA Market Analysis 2017 to 2022 and Forecast 2023 to 2033, By Country

    13.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2017 to 2022

    13.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033

        13.2.1. By Country

            13.2.1.1. GCC Countries

            13.2.1.2. South Africa

            13.2.1.3. Rest of Middle East & Africa

        13.2.2. By Product Type

        13.2.3. By End User

    13.3. Market Attractiveness Analysis

        13.3.1. By Country

        13.3.2. By Product Type

        13.3.3. By End User

    13.4. Key Takeaways

14. Key Countries Market Analysis

    14.1. USA

        14.1.1. Pricing Analysis

        14.1.2. Market Share Analysis, 2022

            14.1.2.1. By Product Type

            14.1.2.2. By End User

    14.2. Canada

        14.2.1. Pricing Analysis

        14.2.2. Market Share Analysis, 2022

            14.2.2.1. By Product Type

            14.2.2.2. By End User

    14.3. Brazil

        14.3.1. Pricing Analysis

        14.3.2. Market Share Analysis, 2022

            14.3.2.1. By Product Type

            14.3.2.2. By End User

    14.4. Mexico

        14.4.1. Pricing Analysis

        14.4.2. Market Share Analysis, 2022

            14.4.2.1. By Product Type

            14.4.2.2. By End User

    14.5. Germany

        14.5.1. Pricing Analysis

        14.5.2. Market Share Analysis, 2022

            14.5.2.1. By Product Type

            14.5.2.2. By End User

    14.6. UK

        14.6.1. Pricing Analysis

        14.6.2. Market Share Analysis, 2022

            14.6.2.1. By Product Type

            14.6.2.2. By End User

    14.7. France

        14.7.1. Pricing Analysis

        14.7.2. Market Share Analysis, 2022

            14.7.2.1. By Product Type

            14.7.2.2. By End User

    14.8. Spain

        14.8.1. Pricing Analysis

        14.8.2. Market Share Analysis, 2022

            14.8.2.1. By Product Type

            14.8.2.2. By End User

    14.9. Italy

        14.9.1. Pricing Analysis

        14.9.2. Market Share Analysis, 2022

            14.9.2.1. By Product Type

            14.9.2.2. By End User

    14.10. China

        14.10.1. Pricing Analysis

        14.10.2. Market Share Analysis, 2022

            14.10.2.1. By Product Type

            14.10.2.2. By End User

    14.11. India

        14.11.1. Pricing Analysis

        14.11.2. Market Share Analysis, 2022

            14.11.2.1. By Product Type

            14.11.2.2. By End User

    14.12. Australia & New Zealand

        14.12.1. Pricing Analysis

        14.12.2. Market Share Analysis, 2022

            14.12.2.1. By Product Type

            14.12.2.2. By End User

    14.13. Association of Southeast Asian Nations (ASEAN)

        14.13.1. Pricing Analysis

        14.13.2. Market Share Analysis, 2022

            14.13.2.1. By Product Type

            14.13.2.2. By End User

    14.14. Japan

        14.14.1. Pricing Analysis

        14.14.2. Market Share Analysis, 2022

            14.14.2.1. By Product Type

            14.14.2.2. By End User

    14.15. GCC Countries

        14.15.1. Pricing Analysis

        14.15.2. Market Share Analysis, 2022

            14.15.2.1. By Product Type

            14.15.2.2. By End User

    14.16. South Africa

        14.16.1. Pricing Analysis

        14.16.2. Market Share Analysis, 2022

            14.16.2.1. By Product Type

            14.16.2.2. By End User

15. Market Structure Analysis

    15.1. Competition Dashboard

    15.2. Competition Benchmarking

    15.3. Market Share Analysis of Top Players

        15.3.1. By Regional

        15.3.2. By Product Type

        15.3.3. By End User

16. Competition Analysis

    16.1. Competition Deep Dive

        16.1.1. Medtronic plc

            16.1.1.1. Overview

            16.1.1.2. Product Portfolio

            16.1.1.3. Profitability by Market Segments

            16.1.1.4. Sales Footprint

            16.1.1.5. Strategy Overview

                16.1.1.5.1. Marketing Strategy

        16.1.2. NuVasive, Inc.

            16.1.2.1. Overview

            16.1.2.2. Product Portfolio

            16.1.2.3. Profitability by Market Segments

            16.1.2.4. Sales Footprint

            16.1.2.5. Strategy Overview

                16.1.2.5.1. Marketing Strategy

        16.1.3. Stryker Corporation

            16.1.3.1. Overview

            16.1.3.2. Product Portfolio

            16.1.3.3. Profitability by Market Segments

            16.1.3.4. Sales Footprint

            16.1.3.5. Strategy Overview

                16.1.3.5.1. Marketing Strategy

        16.1.4. Zimmer Biomet Holdings

            16.1.4.1. Overview

            16.1.4.2. Product Portfolio

            16.1.4.3. Profitability by Market Segments

            16.1.4.4. Sales Footprint

            16.1.4.5. Strategy Overview

                16.1.4.5.1. Marketing Strategy

        16.1.5. Orthofix International N.V.

            16.1.5.1. Overview

            16.1.5.2. Product Portfolio

            16.1.5.3. Profitability by Market Segments

            16.1.5.4. Sales Footprint

            16.1.5.5. Strategy Overview

                16.1.5.5.1. Marketing Strategy

        16.1.6. Anika Therapeutics, Inc.

            16.1.6.1. Overview

            16.1.6.2. Product Portfolio

            16.1.6.3. Profitability by Market Segments

            16.1.6.4. Sales Footprint

            16.1.6.5. Strategy Overview

                16.1.6.5.1. Marketing Strategy

        16.1.7. DePuy Synthes

            16.1.7.1. Overview

            16.1.7.2. Product Portfolio

            16.1.7.3. Profitability by Market Segments

            16.1.7.4. Sales Footprint

            16.1.7.5. Strategy Overview

                16.1.7.5.1. Marketing Strategy

        16.1.8. Bioventus

            16.1.8.1. Overview

            16.1.8.2. Product Portfolio

            16.1.8.3. Profitability by Market Segments

            16.1.8.4. Sales Footprint

            16.1.8.5. Strategy Overview

                16.1.8.5.1. Marketing Strategy

        16.1.9. Arthrex, Inc.

            16.1.9.1. Overview

            16.1.9.2. Product Portfolio

            16.1.9.3. Profitability by Market Segments

            16.1.9.4. Sales Footprint

            16.1.9.5. Strategy Overview

                16.1.9.5.1. Marketing Strategy

        16.1.10. SeaSpine Holdings Corporation

            16.1.10.1. Overview

            16.1.10.2. Product Portfolio

            16.1.10.3. Profitability by Market Segments

            16.1.10.4. Sales Footprint

            16.1.10.5. Strategy Overview

                16.1.10.5.1. Marketing Strategy

        16.1.11. Sanofi SA

            16.1.11.1. Overview

            16.1.11.2. Product Portfolio

            16.1.11.3. Profitability by Market Segments

            16.1.11.4. Sales Footprint

            16.1.11.5. Strategy Overview

                16.1.11.5.1. Marketing Strategy

        16.1.12. Djo Global, Inc.

            16.1.12.1. Overview

            16.1.12.2. Product Portfolio

            16.1.12.3. Profitability by Market Segments

            16.1.12.4. Sales Footprint

            16.1.12.5. Strategy Overview

                16.1.12.5.1. Marketing Strategy

        16.1.13. Seikagaku Corporation

            16.1.13.1. Overview

            16.1.13.2. Product Portfolio

            16.1.13.3. Profitability by Market Segments

            16.1.13.4. Sales Footprint

            16.1.13.5. Strategy Overview

                16.1.13.5.1. Marketing Strategy

        16.1.14. RTI Surgical, Inc.

            16.1.14.1. Overview

            16.1.14.2. Product Portfolio

            16.1.14.3. Profitability by Market Segments

            16.1.14.4. Sales Footprint

            16.1.14.5. Strategy Overview

                16.1.14.5.1. Marketing Strategy

        16.1.15. Heraeus Holding GmbH

            16.1.15.1. Overview

            16.1.15.2. Product Portfolio

            16.1.15.3. Profitability by Market Segments

            16.1.15.4. Sales Footprint

            16.1.15.5. Strategy Overview

                16.1.15.5.1. Marketing Strategy

        16.1.16. Fidia Pharma USA Inc.

            16.1.16.1. Overview

            16.1.16.2. Product Portfolio

            16.1.16.3. Profitability by Market Segments

            16.1.16.4. Sales Footprint

            16.1.16.5. Strategy Overview

                16.1.16.5.1. Marketing Strategy

        16.1.17. TRB Chemedica International SA

            16.1.17.1. Overview

            16.1.17.2. Product Portfolio

            16.1.17.3. Profitability by Market Segments

            16.1.17.4. Sales Footprint

            16.1.17.5. Strategy Overview

                16.1.17.5.1. Marketing Strategy

        16.1.18. Allosource

            16.1.18.1. Overview

            16.1.18.2. Product Portfolio

            16.1.18.3. Profitability by Market Segments

            16.1.18.4. Sales Footprint

            16.1.18.5. Strategy Overview

                16.1.18.5.1. Marketing Strategy

        16.1.19. Musculoskeletal Transplant Foundation, Inc.

            16.1.19.1. Overview

            16.1.19.2. Product Portfolio

            16.1.19.3. Profitability by Market Segments

            16.1.19.4. Sales Footprint

            16.1.19.5. Strategy Overview

                16.1.19.5.1. Marketing Strategy

        16.1.20. Ito Co., Ltd.

            16.1.20.1. Overview

            16.1.20.2. Product Portfolio

            16.1.20.3. Profitability by Market Segments

            16.1.20.4. Sales Footprint

            16.1.20.5. Strategy Overview

                16.1.20.5.1. Marketing Strategy

17. Assumptions & Acronyms Used

18. Research Methodology

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