Monoclonal Gammopathy of Undetermined Significance (MGUS) Management Market Snapshot (2023 to 2033)

The global monoclonal gammopathy of undetermined significance (MGUS) management market is expected to garner a market value of USD 27 million in 2023 and is expected to accumulate a market value of USD 53.11 million by registering a CAGR of 7% in the forecast period 2023 to 2033. The market for Monoclonal Gammopathy of Undetermined Significance (MGUS) Management registered a CAGR of 4% in the historical period 2018 to 2022.

The monoclonal gammopathy of undetermined significance (MGUS) management market is a segment of the healthcare industry that deals with the effective management of the condition. The market offers a range of products and services for its effective management and treatment such as immunomodulatory drugs and proteasome inhibitors, Chemotherapy, and Stem cell transplant.

Report Attribute Details
Expected Market Value (2023) USD 27 million
Anticipated Forecast Value (2033) USD 53.11 million
Projected Growth Rate (2023 to 2033) 7% CAGR

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2018 to 2022 Monoclonal Gammopathy of Undetermined Significance (MGUS) Management Market Demand Analysis vs. Forecast 2023 to 2033

According to market research and competitive intelligence provider, Future Market Insights- the market for Monoclonal Gammopathy of Undetermined Significance (MGUS) Management reflected a value CAGR of 4% during the historical period, 2018 to 2022.

The market for Monoclonal Gammopathy of Undetermined Significance (MGUS) Management is gaining prominence as it is considered a precancerous condition that progresses to a more serious blood cancer like multiple myeloma, but this progression is not always the case. Furthermore, the increasing incidence of blood cancers and the need for improved diagnosis and treatment options, is expected to drive demand for these treatments.

In its new study, Future Market Insights (FMI) offers insights about key factors driving demand for Monoclonal Gammopathy of Undetermined Significance (MGUS) Management. In the years to come, increasing focus by government organizations and private agencies like WHO and pharmaceutical companies to create awareness of Monoclonal Gammopathy of Undetermined Significance (MGUS) Managements is fuelling the market growth. Thus, the market for Monoclonal Gammopathy of Undetermined Significance (MGUS) Management is expected to register a CAGR of 7% in the forecast period 2023 to 2033.

Which are Some Prominent Drivers of the Monoclonal Gammopathy of Undetermined Significance (MGUS) Management Market?

Growing advancements in diagnostic and treatment options of MGUS to push the market growth

The global market for monoclonal gammopathy of undetermined significance (MGUS) management is primarily driven by the incidence of blood cancers, including multiple myeloma, the development of new and effective treatment options, advancements in treatment technologies and development of new diagnostic technologies and the availability of more effective treatments.

According to American Cancer Society estimates in January 2022, about 60,650 new cases of leukemia and 24,000 deaths from leukemia and there were around 11,450 deaths due to acute myeloid leukemia in the United States in the year 2022. Aging population is another factor contributing to the growth of the Monoclonal Gammopathy of Undetermined Significance (MGUS) Management market. As people get older, their risk of developing conditions increases, which is expected to drive demand for these treatments. The prevalence of Monoclonal Gammopathy of Undetermined Significance (MGUS) Management (HE) has increased in recent years, driven by a combination of demographic, technological, and awareness factors.

For instance, in December 2020, the Leukemia and Lymphoma Society (LLS) initiated a collaboration to form alliances with leading cancer institutions and foundations to co-fund nearly USD 17 million in research grants, to progress the research in finding effective treatment options for patients with leukemia, lymphoma, myeloma, and other blood cancers.

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What are the Challenges Faced by the Monoclonal Gammopathy of Undetermined Significance (MGUS) Management Market?

Expensive Cost of Treatment to restrict Market Growth

The market is projected to get significantly affected by challenging factors such as limited availability and high cost of advanced Monoclonal Gammopathy of Undetermined Significance (MGUS) Management options.

Expensive treatments and related costs such as hospitalization, intensive care, or specialized diagnostic tests, are expected to hinder the market growth. Furthermore, poor healthcare infrastructure, especially in developing countries, can limit access to Monoclonal Gammopathy of Undetermined Significance (MGUS) Management and the availability of diagnostic and therapeutic options.

Region-Wise Insights

How is the Monoclonal Gammopathy of Undetermined Significance (MGUS) Management Market Turning Out in the Asia Pacific Region?

Improvement in healthcare spending propelling growth of the market in Asia Pacific

The Asia Pacific is expected to exhibit a significant growth rate of all regions over the forecast period, with a share of 20% during the forecast period. The growth is owed to increased awareness, significant increases in healthcare spending, and a rising frequency of the Monoclonal Gammopathy of Undetermined Significance (MGUS) Management Market in the region. Asia Pacific is an emerging market due to the increase in point of care approach to health & care. Increasing number of hospitals in India and China makes a promising market for the market worldwide.

What are the Factors Boosting the Market for Monoclonal Gammopathy of Undetermined Significance (MGUS) Management in North America?

Increasing Prevalence of Skin Conditions Shaping Landscape for Monoclonal Gammopathy of Undetermined Significance (MGUS) Management in North America

North America is anticipated to acquire a market share of about 40% in the forecast period. This growth is attributable to the rising prevalence of the condition in the region along with the high healthcare expenditure and a large geriatric population. The United States of America holds the highest share in the North American market, followed by Canada.

Presence of a large number of pharmaceutical companies, which are investing heavily in the development of new, targeted treatments for the condition, high level of healthcare expenditure and a growing aging population are some of the factors responsible for the growth of the market in the region.

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Category-Wise Insights

By End-users, Which Segment is Likely to Account for a Significant Share?

Hospitals to take the lead and drive market growth

According to the FMI analysis, Hospital pharmacy accounts for the largest market share. The requirement for several hospital stays and visits during the monoclonal gammopathy of undetermined significance (MGUS) management treatment facilitates the growth of this segment.

The majority of the serious venous diseases involving blood clotting are treated in hospitals, and with the availability of trained medical personnel, it is simpler to control an individual's health more correctly.

Start-up Scenario

Key start-ups in the monoclonal gammopathy of undetermined significance (MGUS) management market include-

  • ElevateBio is providing translational research services for the portfolio of cell and gene therapy. It offers transformative therapy along with other translational research like process development, cGMP manufacturing, clinical development, regulatory affairs, and commercial operations.
  • CTI Biopharma is the developer of targeted small molecule therapeutics for blood cancer. Their flagship product Pixantrone was granted conditional marketing approval in the EU, as a monotherapy for the treatment of adult patients with multiply relapsed or refractory aggressive B-cell non-Hodgkin lymphomas. Other drugs in the pipeline are Pacritinib (myelofibrosis and relapsed acute myeloid leukemia), Tosedostat (relapsed acute myeloid leukemia and myelodysplastic syndrome), and Paclitaxel poliglumex (ovarian cancer).
  • Orca Bio is a developer of Allogeneic cell therapy for blood, genetic and immune diseases. It uses OrcaSort technology that is an enabling feature for the scalability and high-precision of the manufacturing platform. It also helps in the isolation and purification of stem cells and immune cells used in hematopoietic cell grafts. The components of the technology are optimized for performance and designed to fit seamlessly into the clinical processing of apheresis products.

Market Competition

Key players in the market include pharmaceutical companies such as Janssen Biotech, Inc., Pfizer, Inc., Amgen, Inc., Roche Holding AG, Celgene Corporation (Acquired by Bristol-Myers Squibb), Novartis AG, Merck & Co., Inc., Sanofi S.A, Takeda Pharmaceutical Company Limited and Gilead Sciences, Inc. along with healthcare providers and technology companies among other global players.

  • In January 2022, Kura Oncology, Inc. announced that the USA Food and Drug Administration (FDA) has lifted the partial clinical hold on their KOMET-001 Phase 1b study of the drug KO-539 for the treatment of relapsed or refractory acute myeloid leukemia (AML). This allows the company to proceed with the study to evaluate the safety and efficacy of KO-539 in patients with AML.
  • In June 2021, Rylaze is a recombinant asparaginase product that was approved by the US FDA for the treatment of acute lymphoblastic leukemia (ALL) or lymphoblastic lymphoma (LBL) in pediatric and adult patients who have developed hypersensitivity to E. coli-derived asparaginase. The approval of Rylaze was based on the results of clinical trials that demonstrated its efficacy as a component of a multi-agent chemotherapeutic regimen in treating these types of blood cancers.

Report Scope

Report Attribute Details
Market Value in 2023 USD 27 million
Market Value in 2033 USD 53.11 million
Growth Rate CAGR of 7% from 2023 to 2033
Base Year for Estimation 2022
Historical Data 2018 to 2022
Forecast Period 2023 to 2033
Quantitative Units Revenue in USD Million and CAGR from 2023 to 2033
Report Coverage Revenue Forecast, Volume Forecast, Company Ranking, Competitive Landscape, Growth Factors, Trends, and Pricing Analysis
Segments Covered Drug Class, Diagnosis, Distribution Channel, End User, Region
Regions Covered

North America; Latin America; Europe; East Asia; South Asia; Oceania; Middle East & Africa

Key Countries Profiled United States, Canada, Brazil, Mexico, Germany, United Kingdom, France, Spain, Italy, Malaysia, India, Singapore, Thailand, China, Japan, South Korea, Australia, New Zealand, GCC Countries, South Africa, Israel
Key Companies Profiled PhaseBio Pharmaceuticals Inc.; Pfizer Inc.; Amgen Inc.,; Array Biopharma Inc.; AstraZeneca; Sanofi-Aventis US LLC; F. Hoffmann-La Roche Ltd; Merck & Co. Inc.; Siemens Healthcare Private Limited; HYCOR Biomedical, Inc.; Omega Diagnostics Group PLC
Customization Available Upon Request
Table of Content
  • 1. Executive Summary | Monoclonal Gammopathy of Undermined Significance (MGUS) Management Market
  • 2. Market Overview
  • 3. Market Background
  • 4. Global Market Analysis 2023 to 2033 and Forecast, 2023 to 2033
  • 5. Global Market Analysis 2023 to 2033 and Forecast 2023 to 2033, By Drug Class
    • 5.1. Alendronate
    • 5.2. Risedronate
    • 5.3. Ibandronate
    • 5.4. Zoledronic Acid
  • 6. Global Market Analysis 2023 to 2033 and Forecast 2023 to 2033, By Diagnosis
    • 6.1. Blood tests
    • 6.2. Urine tests
    • 6.3. Imaging tests
    • 6.4. Bone marrow tests
  • 7. Global Market Analysis 2023 to 2033 and Forecast 2023 to 2033, By Distribution Channel
    • 7.1. Hospital Pharmacies
    • 7.2. Retail Pharmacies
    • 7.3. Online Pharmacies
  • 8. Global Market Analysis 2023 to 2033 and Forecast 2023 to 2033, By End-user
    • 8.1. Hospitals
    • 8.2. Clinical Laboratories
  • 9. Global Market Analysis 2023 to 2033 and Forecast 2023 to 2033, By Region
    • 9.1. North America
    • 9.2. Latin America
    • 9.3. Europe
    • 9.4. South Asia
    • 9.5. East Asia
    • 9.6. Oceania
    • 9.7. MEA
  • 10. North America Market Analysis 2023 to 2033 and Forecast 2023 to 2033, By Country
  • 11. Latin America Market Analysis 2023 to 2033 and Forecast 2023 to 2033, By Country
  • 12. Europe Market Analysis 2023 to 2033 and Forecast 2023 to 2033, By Country
  • 13. South Asia Market Analysis 2023 to 2033 and Forecast 2023 to 2033, By Country
  • 14. East Asia Market Analysis 2023 to 2033 and Forecast 2023 to 2033, By Country
  • 15. Oceania Market Analysis 2023 to 2033 and Forecast 2023 to 2033, By Country
  • 16. MEA Market Analysis 2023 to 2033 and Forecast 2023 to 2033, By Country
  • 17. Key Countries Market Analysis
  • 18. Market Structure Analysis
  • 19. Competition Analysis
    • 19.1. Pfizer Inc.
    • 19.2. PhaseBio Pharmaceuticals Inc.
    • 19.3. Array Biopharma Inc.
    • 19.4. AstraZeneca
    • 19.5. Sanofi-Aventis US LLC
    • 19.6. Hoffmann-La Roche Ltd
    • 19.7. Merck & Co. Inc.
    • 19.8. Siemens Healthcare Private Limited
    • 19.9. Omega Diagnostics Group PLC
    • 19.10. HYCOR Biomedical, Inc.
  • 20. Assumptions & Acronyms Used
  • 21. Research Methodology

Key Segments Profiled in the Monoclonal Gammopathy of Undetermined Significance (MGUS) Management Industry Survey

Drug Class:

  • Alendronate
  • Risedronate
  • Ibandronate
  • Zoledronic Acid

Distribution Channel:

  • Hospital Pharmacies
  • Retail Pharmacies
  • Online Pharmacies

Diagnosis:

  • Blood Tests
  • Urine Tests
  • Imaging Tests
  • Bone Marrow Tests

End Users:

  • Hospitals
  • Speciality Centers

Region:

  • North America
  • Latin America
  • Europe
  • East Asia
  • South Asia
  • Oceania
  • Middle East & Africa

Frequently Asked Questions

What is the Estimated Size of the Market in 2023?

The market is estimated to secure a revenue of USD 27 million by 2023.

What is the Expected Market Size of the Market?

The market is expected to reach a value of USD 53.11 million by the end of 2033.

What is the Potential Growth Rate of the Market?

The market is predicted to progress at a CAGR of 7% through 2033.

What Drives the Market for Monoclonal Gammopathy of Undetermined Significance (MGUS) Management?

Growing advancements in diagnostic and treatment options of MGUS.

What Boosts Sales in Asia Pacific Market?

Improvement in healthcare spending propelling market growth in Asia Pacific, with a share of 20% through 2033.

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Monoclonal Gammopathy of Undetermined Significance (MGUS) Management Market

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