Newly-released In Situ Hybridization industry analysis report by Future Market Insights reveals that global sales of In Situ Hybridization in 2021 were held at US$ 1.3 billion. With a 10.6% CAGR, the market is projected to reach a valuation of US$ 3.9 billion by 2032. Fluorescent In Situ Hybridization (FISH) is expected to be the highest revenue-generating technology, accounting for an absolute dollar opportunity of nearly US$ 2.5 billion from 2022 to 2032.
| Attribute | Details |
|---|---|
| Global In Situ Hybridization Market (2022) | US$ 1.4 billion |
| Global In Situ Hybridization Market (2032) | US$ 3.9 billion |
| Global In Situ Hybridization Market CAGR (2022 to 2032) | 10.6% |
| The USA In Situ Hybridization Market CAGR (2022 to 2032) | 10.8% |
| Key Companies Profiled |
|
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As per the In Situ Hybridization industry research by Future Market Insights - a market research and competitive intelligence provider, historically, from 2017 to 2021, the market value of the In Situ Hybridization industry increased at around 9.9% CAGR, wherein, countries such as the USA, the Kingdom, China, South Korea, and Japan held a significant share in the global market. The market is projected to grow at a CAGR of 10.6% over the coming 10 years.
Some of the key factors driving the market include the rising prevalence of specific disorders, increased investments in in-vitro diagnostics, and technological advances in In Situ Hybridization (ISH). Various research institutions and organizations have spent the last few years conducting extensive R&D in order to develop a technology that can evaluate the molecular profiles of single cells. For example, BIO-PROTOCOL created the Proximity Ligation in the In Situ Hybridization process. The method is expected to be high-performing, low-cost, quick multiplex, and simple to apply.
In situ hybridization technology has become more economical, making it more accessible to developing countries, which are more susceptible to infections and diseases. Regulatory organizations have implemented a variety of regulations and measures to raise public awareness. In August 2021, for example, the Federal Capital Public Health Agency in Nigeria cooperated with WHO to raise infectious illness awareness.
The utilization of ISH products has grown in recent years, resulting in an increase in the number of specialist contract research organizations. Reveal Biosciences, for example, uses in situ hybridization and other methodologies to deliver tissue research and innovative tissue technology services with strict legal capacity and high samples throughout.
For the past several years, cancer cases have been on the rise all around the world. Over the last few decades, extensive investigations on human diseases have identified recurrent genetic aberrations as potential driving factors for a range of malignancies. Cytogenetic tests, such as ISH, aid in the combination of IHC and DNA FISH in situ, allowing researchers to create, discover and execute next-generation diagnostic approaches. Direct imaging of gene expression in situ at the RNA level gives a new perspective on the interaction between cancer cells and the tumor microenvironment as cancer progresses.
Furthermore, according to a study conducted by McMaster University in Canada, the number of people living with hemophilia has tripled to 1,125,000, up from 400,000 previously. Canada, France, Italy, Australia, the United Kingdom, and New Zealand are the countries most affected. The market is anticipated to benefit from this growth.
Principal Consultant
North America is expected to be the most lucrative region in the In Situ Hybridization Market throughout the analysis period. The market in the region is expected to be propelled by significant expenditure in healthcare Research and Development (R&D). The market in North America is projected to cross a valuation of US$ 1.5 billion by 2032.
The USA dominated the In Situ Hybridization market in 2021, accounting for 44.9% of the total revenue. The existence of a large number of market players, as well as encouraging research programs by the regional government, can be credited for the regional market growth.
Other variables contributing to the country's dominance throughout the projection period include high healthcare spending and strict FDA and Health Canada rules. The USA In Situ Hybridization market has the most patents, whereas the Asia Pacific market has a greater marginal rise than the rest of the world. The presence of Health Canada-funded research initiatives and institutes is estimated to spur the market by a little margin.
The In Situ Hybridization market in the United Kingdom was valued at US$ 72.5 million in 2021. The market in the country is expected to reach nearly US$ 217.6 million by 2032. From 2022 to 2032, the market is likely to witness an absolute dollar opportunity of US$ 147.1 million, growing at a CAGR of 11.9%
The In Situ Hybridization market in Japan is projected to reach a valuation of US$ 183.8 million by 2032, growing at a CAGR of 10.1% from 2022 to 2032. The market is likely to garner an absolute dollar opportunity of US$ 114.3 million from 2022 to 2032.
The market in South Korea is expected to reach a US$ 75.1 million market value by 2032, growing at a CAGR of 8.5% from 2022 to 2032. During this period, the market is likely to gross an absolute dollar growth of US$ 42.3 million.
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The Fluorescent In Situ Hybridization (FISH) segment held the largest share of In Situ Hybridization market in 2021, accounting for around 54% of total revenue. This is due to the vast range of uses, including the diagnosis of congenital illnesses such as Edward's Syndrome and Down's Syndrome. The increased use of FISH technology as a result of the rising prevalence and treatment of such diseases is likely to accelerate In Situ Hybridization market growth.
The FISH market's growth is being fueled by low-cost technical advancements. For example, in May 2021, a group of researchers published a report claiming that using chromogen-based RNA in situ hybridization to identify druggable cytokines in atopic dermatitis and psoriasis is an efficient way. Technological progress broadens the scope of In Situ Hybridization and propels segment expansion.
The DNA probe segment held the largest share of in situ hybridization market in 2021, accounting for over 50% of total revenue. However, due to the development of novel nucleic acid-based diagnostic assays and instruments for studying DNA and RNA molecules, the demand for RNA probes grew at a faster rate in the anticipated timeframe.
By hybridization, an RNA probe can indicate the presence of similar nucleic acid sequences. The use of RNA as a hybridization technique is growing due to various advantages, including the fact that the probes are generated in vitro and may be used in practically all applications instead of DNA probes.
Revenue through application dominated the in situ hybridization market in 2021, accounting for over 35% of the total revenue. The expansion is expected to be fueled by an increase in the number of cancer cases. According to the American Cancer Society, about 1.9 million additional cancer cases are projected in the United States in 2021. With the surge in cancer cases, in situ hybridization methods for speedy and accurate diagnosis are in high demand.
Cancer is caused by a variety of reasons, including an aging population, poor health, and the environment. Various organizations are conducting cancer research and are encouraging advancements in cancer therapy. For example, the American Institute for Cancer Research funded around USD 110 million in cancer research grants from 2020 to 2021.
During the pinnacle of the epidemic, there was a significant drop in cancer and precancer diagnoses, owing to a decline in the number of screening tests done. In recent months, these characteristics may have hampered the utility of In Situ Hybridization as a molecular tool for cancer diagnosis. However, in the forthcoming years, the considerable development of FISH probes to visualize SARS-CoV-2 RNA in infected cells can have a favorable impact on the sector.
COVID-19 was also a motivating force behind the FISH market's expansion. The University of Oxford and the University of Warwick partnered in June 2021 to develop an in situ hybridization approach for detecting the COVID-19 virus in twenty minutes. This method has previously been used to detect diseases such as the Epstein-Barr virus and HIV inside cells. The In Situ Hybridization market growth is likely to accelerate in the near future because of these changes.
Some of the key players such as Merck KGaA, Thermo Fisher Scientific, Agilent Technologies, PerkinElmer, and Leica Biosystems Nussloch GmbH.
Some of the recent developments of key In Situ Hybridization providers are as follows:
Similarly, recent developments related to companies offering In Situ Hybridization have been tracked by the team at Future Market Insights, which are available in the full report.
The global In Situ Hybridization market is worth more than US$ 1.4 billion at present.
The value of In Situ Hybridization is projected to increase at a CAGR of around 10.6% from 2022 to 2032.
The value of In Situ Hybridization increased at a CAGR of around 9.9% from 2017 to 2021.
Top five players of In Situ Hybridization market include Merck KGaA, Thermo Fisher Scientific, Agilent Technologies, PerkinElmer, and Leica Biosystems Nussloch GmbH
The top 5 countries driving demand for In Situ Hybridization are the USA, the United Kingdom., China, Japan, South Korea
1. Executive Summary | In Situ Hybridization Market
1.1. Global Market Outlook
1.2. Summary of Statistics
1.3. Key Market Characteristics & Attributes
1.4. Analysis and Recommendations
2. Market Overview
2.1. Market Coverage
2.2. Market Definition
3. Market Risks and Trends Assessment
3.1. Risk Assessment
3.1.1. COVID-19 Crisis and Impact on In Situ Hybridization
3.1.2. COVID-19 Impact Benchmark with Previous Crisis
3.1.3. Impact on Market Value (US$ million)
3.1.4. Assessment by Key Countries
3.1.5. Assessment by Key Market Segments
3.1.6. Action Points and Recommendation for Suppliers
3.2. Key Trends Impacting the Market
3.3. Formulation and Probe Type Development Trends
4. Market Background
4.1. Market, by Key Countries
4.2. Market Opportunity Assessment (US$ million)
4.2.1. Total Available Market
4.2.2. Serviceable Addressable Market
4.2.3. Serviceable Obtainable Market
4.3. Market Scenario Forecast
4.3.1. Demand in optimistic Scenario
4.3.2. Demand in Likely Scenario
4.3.3. Demand in Conservative Scenario
4.4. Investment Feasibility Analysis
4.4.1. Investment in Established Markets
4.4.1.1. In Short Term
4.4.1.2. In Long Term
4.4.2. Investment in Emerging Markets
4.4.2.1. In Short Term
4.4.2.2. In Long Term
4.5. Forecast Factors - Relevance & Impact
4.5.1. Top Companies Historical Growth
4.5.2. Growth in Automation, By Country
4.5.3. Adoption Rate, By Country
4.6. Market Dynamics
4.6.1. Market Driving Factors and Impact Assessment
4.6.2. Prominent Market Challenges and Impact Assessment
4.6.3. Market Opportunities
4.6.4. Prominent Trends in the Global Market & Their Impact Assessment
5. Key Success Factors
5.1. Manufacturers’ Focus on Low Penetration High Growth Markets
5.2. Banking on with Segments High Incremental Opportunity
5.3. Peer Benchmarking
6. Global Market Demand Analysis 2017 to 2021 and Forecast, 2022 to 2032
6.1. Historical Market Analysis, 2017 to 2021
6.2. Current and Future Market Projections, 2022 to 2032
6.3. Y-o-Y Growth Trend Analysis
7. Global Market Value Analysis 2017 to 2021 and Forecast, 2022 to 2032
7.1. Historical Market Value (US$ million) Analysis, 2017 to 2021
7.2. Current and Future Market Value (US$ million) Projections, 2022 to 2032
7.2.1. Y-o-Y Growth Trend Analysis
7.2.2. Absolute $ Opportunity Analysis
8. Global Market Analysis 2017 to 2021 and Forecast 2022 to 2032, By Technology
8.1. Introduction / Key Findings
8.2. Historical Market Size (US$ million) Analysis By Technology, 2017 to 2021
8.3. Current and Future Market Size (US$ million) Analysis and Forecast By Technology, 2022 to 2032
8.3.1. Fluorescent (FISH)
8.3.2. Chromogenic (CISH)
8.4. Market Attractiveness Analysis By Technology
9. Global Market Analysis 2017 to 2021 and Forecast 2022 to 2032, By Probe Type
9.1. Introduction / Key Findings
9.2. Historical Market Size (US$ million) Analysis By Probe Type, 2017 to 2021
9.3. Current and Future Market Size (US$ million) Analysis and Forecast By Probe Type, 2022 to 2032
9.3.1. DNA
9.3.2. RNA
9.4. Market Attractiveness Analysis By Probe Type
10. Global Market Analysis 2017 to 2021 and Forecast 2022 to 2032, By Product Type
10.1. Introduction / Key Findings
10.2. Historical Market Size (US$ million) Analysis By Product Type, 2017 to 2021
10.3. Current and Future Market Size (US$ million) Analysis and Forecast By Product Type, 2022 to 2032
10.3.1. Services
10.3.2. Instruments
10.3.3. Kits & Probes
10.3.4. Software
10.4. Market Attractiveness Analysis By Product Type
11. Global Market Analysis 2017 to 2021 and Forecast 2022 to 2032, By Application
11.1. Introduction / Key Findings
11.2. Historical Market Size (US$ million) Analysis By Application, 2017 to 2021
11.3. Current and Future Market Size (US$ million) Analysis and Forecast By Application, 2022 to 2032
11.3.1. Cancer
11.3.2. Cytogenics
11.3.3. Developmental Biology
11.3.4. Infectious Diseases
11.3.5. Other Applications
11.4. Market Attractiveness Analysis By Testing Application
12. Global Market Analysis 2017 to 2021 and Forecast 2022 to 2032, By Region
12.1. Introduction
12.2. Historical Market Size (US$ million) Analysis By Region, 2017 to 2021
12.3. Current Market Size (US$ million) & Analysis and Forecast By Region, 2022 to 2032
12.3.1. North America
12.3.2. Latin America
12.3.3. Europe
12.3.4. Asia Pacific
12.3.5. Middle East and Africa (MEA)
12.4. Market Attractiveness Analysis By Region
13. North America Market Analysis 2017 to 2021 and Forecast 2022 to 2032
13.1. Introduction
13.2. Pricing Analysis
13.3. Historical Market Value (US$ million) Trend Analysis By Market Taxonomy, 2017 to 2021
13.4. Market Value (US$ million) & Forecast By Market Taxonomy, 2022 to 2032
13.4.1. By Country
13.4.1.1. The USA
13.4.1.2. Canada
13.4.1.3. Rest of North America
13.4.2. By Technology
13.4.3. By Probe Type
13.4.4. By Application
13.4.5. By Product Type
13.5. Market Attractiveness Analysis
13.5.1. By Country
13.5.2. By Technology
13.5.3. By Probe Type
13.5.4. By Application
13.5.5. By Product Type
14. Latin America Market Analysis 2017 to 2021 and Forecast 2022 to 2032
14.1. Introduction
14.2. Pricing Analysis
14.3. Historical Market Value (US$ million) Trend Analysis By Market Taxonomy, 2017 to 2021
14.4. Market Value (US$ million) & Forecast By Market Taxonomy, 2022 to 2032
14.4.1. By Country
14.4.1.1. Brazil
14.4.1.2. Mexico
14.4.1.3. Rest of Latin America
14.4.2. By Technology
14.4.3. By Probe Type
14.4.4. By Application
14.4.5. By Product Type
14.5. Market Attractiveness Analysis
14.5.1. By Country
14.5.2. By Technology
14.5.3. By Probe Type
14.5.4. By Application
14.5.5. By Product Type
15. Europe Market Analysis 2017 to 2021 and Forecast 2022 to 2032
15.1. Introduction
15.2. Pricing Analysis
15.3. Historical Market Value (US$ million) Trend Analysis By Market Taxonomy, 2017 to 2021
15.4. Market Value (US$ million) & Forecast By Market Taxonomy, 2022 to 2032
15.4.1. By Country
15.4.1.1. Germany
15.4.1.2. France
15.4.1.3. The United Kingdom
15.4.1.4. Italy
15.4.1.5. Benelux
15.4.1.6. Nordic Countries
15.4.1.7. Rest of Europe
15.4.2. By Technology
15.4.3. By Probe Type
15.4.4. By Application
15.4.5. By Product Type
15.5. Market Attractiveness Analysis
15.5.1. By Country
15.5.2. By Technology
15.5.3. By Probe Type
15.5.4. By Application
15.5.5. By Product Type
16. Asia Pacific Market Analysis 2017 to 2021 and Forecast 2022 to 2032
16.1. Introduction
16.2. Pricing Analysis
16.3. Historical Market Value (US$ million) Trend Analysis By Market Taxonomy, 2017 to 2021
16.4. Market Value (US$ million) & Forecast By Market Taxonomy, 2022 to 2032
16.4.1. By Country
16.4.1.1. China
16.4.1.2. Japan
16.4.1.3. South Korea
16.4.1.4. Rest of Asia Pacific
16.4.2. By Technology
16.4.3. By Probe Type
16.4.4. By Application
16.4.5. By Product Type
16.5. Market Attractiveness Analysis
16.5.1. By Country
16.5.2. By Technology
16.5.3. By Probe Type
16.5.4. By Application
16.5.5. By Product Type
17. Middle East and Africa Market Analysis 2017 to 2021 and Forecast 2022 to 2032
17.1. Introduction
17.2. Pricing Analysis
17.3. Historical Market Value (US$ million) Trend Analysis By Market Taxonomy, 2017 to 2021
17.4. Market Value (US$ million) & Forecast By Market Taxonomy, 2022 to 2032
17.4.1. By Country
17.4.1.1. GCC Countries
17.4.1.2. South Africa
17.4.1.3. Turkey
17.4.1.4. Rest of Middle East and Africa
17.4.2. By Technology
17.4.3. By Probe Type
17.4.4. By Application
17.4.5. By Product Type
17.5. Market Attractiveness Analysis
17.5.1. By Country
17.5.2. By Technology
17.5.3. By Probe Type
17.5.4. By Application
17.5.5. By Product Type
18. Key Countries Market Analysis 2017 to 2021 and Forecast 2022 to 2032
18.1. Introduction
18.1.1. Market Value Proportion Analysis, By Key Countries
18.1.2. Global Vs. Country Growth Comparison
18.2. US Market Analysis
18.2.1. Value Proportion Analysis by Market Taxonomy
18.2.2. Value Analysis and Forecast by Market Taxonomy, 2017 to 2032
18.2.2.1. By Technology
18.2.2.2. By Probe Type
18.2.2.3. By Application
18.2.2.4. By Product Type
18.3. Canada Market Analysis
18.3.1. Value Proportion Analysis by Market Taxonomy
18.3.2. Value Analysis and Forecast by Market Taxonomy, 2017 to 2032
18.3.2.1. By Technology
18.3.2.2. By Probe Type
18.3.2.3. By Application
18.3.2.4. By Product Type
18.4. Mexico Market Analysis
18.4.1. Value Proportion Analysis by Market Taxonomy
18.4.2. Value Analysis and Forecast by Market Taxonomy, 2017 to 2032
18.4.2.1. By Technology
18.4.2.2. By Probe Type
18.4.2.3. By Application
18.4.2.4. By Product Type
18.5. Brazil Market Analysis
18.5.1. Value Proportion Analysis by Market Taxonomy
18.5.2. Value Analysis and Forecast by Market Taxonomy, 2017 to 2032
18.5.2.1. By Technology
18.5.2.2. By Probe Type
18.5.2.3. By Application
18.5.2.4. By Product Type
18.6. Germany Market Analysis
18.6.1. Value Proportion Analysis by Market Taxonomy
18.6.2. Value Analysis and Forecast by Market Taxonomy, 2017 to 2032
18.6.2.1. By Technology
18.6.2.2. By Probe Type
18.6.2.3. By Application
18.6.2.4. By Product Type
18.7. France Market Analysis
18.7.1. Value Proportion Analysis by Market Taxonomy
18.7.2. Value Analysis and Forecast by Market Taxonomy, 2017 to 2032
18.7.2.1. By Technology
18.7.2.2. By Probe Type
18.7.2.3. By Application
18.7.2.4. By Product Type
18.8. Italy Market Analysis
18.8.1. Value Proportion Analysis by Market Taxonomy
18.8.2. Value Analysis and Forecast by Market Taxonomy, 2017 to 2032
18.8.2.1. By Technology
18.8.2.2. By Probe Type
18.8.2.3. By Application
18.8.2.4. By Product Type
18.9. BENELUX Market Analysis
18.9.1. Value Proportion Analysis by Market Taxonomy
18.9.2. Value Analysis and Forecast by Market Taxonomy, 2017 to 2032
18.9.2.1. By Technology
18.9.2.2. By Probe Type
18.9.2.3. By Application
18.9.2.4. By Product Type
18.10. The United Kingdom Market Analysis
18.10.1. Value Proportion Analysis by Market Taxonomy
18.10.2. Value Analysis and Forecast by Market Taxonomy, 2017 to 2032
18.10.2.1. By Technology
18.10.2.2. By Probe Type
18.10.2.3. By Application
18.10.2.4. By Product Type
18.11. Nordic Countries Market Analysis
18.11.1. Value Proportion Analysis by Market Taxonomy
18.11.2. Value Analysis and Forecast by Market Taxonomy, 2017 to 2032
18.11.2.1. By Technology
18.11.2.2. By Probe Type
18.11.2.3. By Application
18.11.2.4. By Product Type
18.12. China Market Analysis
18.12.1. Value Proportion Analysis by Market Taxonomy
18.12.2. Value Analysis and Forecast by Market Taxonomy, 2017 to 2032
18.12.2.1. By Technology
18.12.2.2. By Probe Type
18.12.2.3. By Application
18.12.2.4. By Product Type
18.13. Japan Market Analysis
18.13.1. Value Proportion Analysis by Market Taxonomy
18.13.2. Value Analysis and Forecast by Market Taxonomy, 2017 to 2032
18.13.2.1. By Technology
18.13.2.2. By Probe Type
18.13.2.3. By Application
18.13.2.4. By Product Type
18.14. South Korea Market Analysis
18.14.1. Value Proportion Analysis by Market Taxonomy
18.14.2. Value Analysis and Forecast by Market Taxonomy, 2017 to 2032
18.14.2.1. By Technology
18.14.2.2. By Probe Type
18.14.2.3. By Application
18.14.2.4. By Product Type
18.15. GCC Countries Market Analysis
18.15.1. Value Proportion Analysis by Market Taxonomy
18.15.2. Value Analysis and Forecast by Market Taxonomy, 2017 to 2032
18.15.2.1. By Technology
18.15.2.2. By Probe Type
18.15.2.3. By Application
18.15.2.4. By Product Type
18.16. South Africa Market Analysis
18.16.1. Value Proportion Analysis by Market Taxonomy
18.16.2. Value Analysis and Forecast by Market Taxonomy, 2017 to 2032
18.16.2.1. By Technology
18.16.2.2. By Probe Type
18.16.2.3. By Application
18.16.2.4. By Product Type
18.17. Turkey Market Analysis
18.17.1. Value Proportion Analysis by Market Taxonomy
18.17.2. Value Analysis and Forecast by Market Taxonomy, 2017 to 2032
18.17.2.1. By Technology
18.17.2.2. By Probe Type
18.17.2.3. By Application
18.17.2.4. By Product Type
18.17.3. Competition Landscape and Player Concentration in the Country
19. Market Structure Analysis
19.1. Market Analysis by Tier of Companies
19.2. Market Concentration
19.3. Market Share Analysis of Top Players
19.4. Market Presence Analysis
19.4.1. By Regional footprint of Players
19.4.2. Probe Type footprint by Players
20. Competition Analysis
20.1. Competition Dashboard
20.2. Competition Benchmarking
20.3. Competition Deep Dive
20.3.1. Merck KGaA
20.3.1.1. Overview
20.3.1.2. Probe Type Portfolio
20.3.1.3. Sales Footprint
20.3.1.4. Strategy Overview
20.3.2. Thermo Fisher Scientific
20.3.2.1. Overview
20.3.2.2. Probe Type Portfolio
20.3.2.3. Sales Footprint
20.3.2.4. Strategy Overview
20.3.3. Agilent Technologies
20.3.3.1. Overview
20.3.3.2. Probe Type Portfolio
20.3.3.3. Sales Footprint
20.3.3.4. Strategy Overview
20.3.4. PerkinElmer
20.3.4.1. Overview
20.3.4.2. Probe Type Portfolio
20.3.4.3. Sales Footprint
20.3.4.4. Strategy Overview
20.3.5. Leica Biosystems Nussloch GmbH
20.3.5.1. Overview
20.3.5.2. Probe Type Portfolio
20.3.5.3. Sales Footprint
20.3.5.4. Strategy Overview
20.3.6. BIO VIEW
20.3.6.1. Overview
20.3.6.2. Probe Type Portfolio
20.3.6.3. Sales Footprint
20.3.6.4. Strategy Overview
20.3.7. NeoGenomics Laboratories, Inc.
20.3.7.1. Overview
20.3.7.2. Probe Type Portfolio
20.3.7.3. Sales Footprint
20.3.7.4. Strategy Overview
20.3.8. Bio-Rad Laboratories, Inc.
20.3.8.1. Overview
20.3.8.2. Probe Type Portfolio
20.3.8.3. Sales Footprint
20.3.8.4. Strategy Overview
20.3.9. Oxford Gene Technology
20.3.9.1. Overview
20.3.9.2. Probe Type Portfolio
20.3.9.3. Sales Footprint
20.3.9.4. Strategy Overview
20.3.10. Advanced Cell Diagnostics, Inc.
20.3.10.1. Overview
20.3.10.2. Probe Type Portfolio
20.3.10.3. Sales Footprint
20.3.10.4. Strategy Overview
21. Assumptions and Acronyms Used
22. Research Methodology
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In Situ Hybridization Market
