Hydroxyapatite Market Outlook (2023 to 2033)

The global Hydroxyapatite Market was valued at USD 480.2 million in 2022 and is likely to reach USD 501.8 million by 2023. Furthermore, with rising demand from the healthcare industry, the overall sales of hydroxyapatite are expected to grow at a robust CAGR of 7.8% between 2023 and 2033, topping a valuation of USD 1,063.5 million by 2033.

Hydroxyapatite is a naturally occurring mineral form of calcium apatite, generally used for bone repair and bone regeneration. It is being increasingly utilized in dental and orthopedic applications due to its optimum stability, biocompatibility, bioactivity, osteo-conductivity, and non-toxic nature.

Thermodynamically, hydroxyapatite is the most stable calcium phosphate compound under physical conditions such as temperature, pH, and composition of body fluids.

Due to the sheer growing preference for biomaterials, the dental implant and prosthetic industry are expected to have a direct impact on hydroxyapatite consumption. Over the forecast period, biochemical research is projected to propel the hydroxyapatite industry growth by expanding the application areas for 3-D printing and artificial bones.

Attribute Key Statistics
Hydroxyapatite Market Base Value (2022A) USD 480.2 million
Estimated Market Size (2023E) USD 501.8 million
Projected Market Size (2033F) USD 1,063.5 million
Value-based CAGR (2023 to 2033) 7.8%
Collective Value Share: Top 3 Countries (2023E) 53.7%

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2018 to 2022 Hydroxyapatite Demand Outlook Compared to 2023 to 2033 Forecast

The global hydroxyapatite market witnessed a CAGR of 4.1% during the historical period of 2018 to 2022. However, with the rising prevalence of medical conditions like periodontal bone defects and the growing usage of hydroxyapatite in treating these conditions, the overall hydroxyapatite industry is poised to grow at 7.8% CAGR between 2023 and 2033.

Hydroxyapatite is mostly used for bone repair and bone regeneration in the form of granules, blocks, and scaffolds, by itself or as a composite with polymers or other materials. Besides this, it finds application in biochemical research, surgical procedures, medicines, bioceramic coatings, etc.

Thus, the rapid expansion of medical & pharmaceuticals, cosmetics, food & other industries. worldwide is projected to eventually trigger the growth of the hydroxyapatite market during the forecast period.

Similarly, continuous technological advancements in various end-use industries and the consumption of hydroxyapatite in various technologies such as 3-D printing is expected to create sales prospects within the global hydroxyapatite industry over the forthcoming period.

What are the Key Trends Driving the Global Hydroxyapatite Powder Market?

Growing Demand for Implants Due to the Surge in Geriatric Population Pushing the Demand for Hydroxyapatite

In the elderly population, tooth loss has become a prevalent issue. According to the World Bank, the population over 65 has increased significantly during the past ten years. Various studies have revealed that the chances of developing ailments including osteoarthritis, knee, joint, and hip issues, as well as dental decay, are higher in the aging population.

There have also been escalating accidents worldwide that caused damage to bones, teeth, etc. The number of patients seeking such implants and replacements has increased significantly. As a result of this, there has been a rise in hydroxyapatite demand.

With an aging population and a surge in health issues across the world, demand for implants is expected to rise during the forecast period. This is projected to bolster the growth of the hydroxyapatite industry.

Rising Spending on Facial Rejuvenation Treatments to Create Opportunities for Hydroxyapatite Market

In the past ten years, non-surgical procedures for facial rejuvenation have become increasingly popular. There are numerous causes for this. Patients who want to see quick, natural results with the least amount of difficulty are drawn to these treatments since they are less expensive and need less recovery time than surgical procedures.

For these procedures, options including Botox and dermal fillers are available. As an alternative to collagen- and hyaluronic acid-based fillers, hydroxyapatite-based fillers are an excellent choice.

In terms of materials for wrinkle fillers, hydroxyapatite makes sense. Human teeth and bones naturally contain this harmless, biodegradable, and biocompatible mineral.

The popular filler Radiesse, which is made of hydroxyapatite, is made up of tiny hydroxyapatite microspheres (particles) contained in a gel-like fluid. Moderate to facial folds, deep wrinkles, lipoatrophy, and similar issues are the most typical uses of hydroxyapatite-based cosmetic fillers.

Thus, increasing spending by consumers on facial rejuvenation treatments is expected to boost the growth of the hydroxyapatite industry during the forecast period.

Nikhil Kaitwade
Nikhil Kaitwade

Principal Consultant

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What Are the Factors that May Limit the Growth of the Hydroxyapatite Market?

Certain factors may hinder the market growth of the hydroxyapatite market during the forecast period. One of the key factors is the availability of alternatives such as titanium. Titanium and other metal-based implants currently dominate developing-country markets due to a lack of awareness and the fact that metallic implants are relatively cheaper.

Titanium implants have proven to be successful and compatible with body tissues. In the dental industry today, titanium is used in 95 percent of implants. The primary reason for this is that it is a strong, lightweight, non-toxic, and corrosion-resistant material.

Similarly, the high cost of hydroxyapatite implants is also likely to impact market growth during the forecast period.

Country-wise Insights

What is Projected to be the Growth Outlook for the United States Hydroxyapatite Market

Rising Healthcare Spending Boosting Hydroxyapatite Market Growth in the United States

Country The United States
Market Share % (2023) 26.9%

As per FMI’s latest analysis, the United States is projected to continue to dominate the North American hydroxyapatite market during the forecast period, owing to the better healthcare infrastructure, the surge in the number of non-invasive cosmetic surgeries, increasing healthcare spending, and strong presence of leading hydroxyapatite manufacturers.

The rapid rise in healthcare spending is a key factor driving growth in the United States hydroxyapatite market. According to the Centers for Medicare & Medicaid Services, the United States’ healthcare spending grew 9.7% in 2020, reaching USD 4.1 trillion. As a share of the nation's Gross Domestic Product, health spending accounted for 19.7%.

Similarly, as per World Bank data, the population over 65 in the United States accounted for approximately 16.6% of the total population, necessitating more medical attention for tooth decay and gum problems.

Thus, the growing adoption of highly advanced implants across the healthcare industry is expected to boost the demand for hydroxyapatite in the United States market during the assessment period. FMI predicts the United States hydroxyapatite industry to reach around USD 266.2 million by the end of 2033.

Why is the Demand for Hydroxyapatite Rising in China?

Surge in Geriatric Population Driving Demand for Hydroxyapatite Across China

Country China
Market CAGR % (2023 to 2033) 8.1%

China is known as a manufacturing hub due to the large presence of manufacturing industries in the country. As per FMI, China is likely to remain the most dominant market for hydroxyapatite across East Asia during the forecast period.

Demand for hydroxyapatite in China is driven by a rapidly expanding healthcare industry, exploding aging population, rapid economic growth, a surge in the number of cosmetic surgeries, and expanded basic health insurance.

The aging population is one of the major concerns in China and it is expected to fuel the healthcare industry. The aging population necessitates more medical attention & treatment.

In China, the medical implants & orthopedics segment has a fair share in the medical devices market owing to the increasing adoption of surgeries to treat medical abnormalities. According to the International Trade Administration (ITA) dental, orthopedics & prosthetic segment accounted for a 12% share of China’s medical devices market for the year 2020.

In addition to this, as cited by ITA, China registered 264 million people aged 60 and above by the end of 2020, accounting for 18.7% of the total population. This demographic is expected to reach over 300 million by 2025.

The population of China is aging quickly and has a higher frequency of musculoskeletal conditions, especially osteoarthritis, and osteoporosis. The need for orthopedics products has increased as the coverage of basic health insurance has expanded. Hence, the scope of the hydroxyapatite industry in the Chinese market is expected to grow in the forecast period.

The hydroxyapatite industry in China is expected to expand at a CAGR of 8.1% during the forecast period.

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Category-wise Insights

Which Application Holds the Maximum Potential for Hydroxyapatite Market Growth?

Majority of Hydroxyapatite Sales Remain Concentrated in the Dental Industry

Segment Dental
Market Share % (2023) 40.2%

As per FMI, the dental segment is likely to provide lucrative growth opportunities for the hydroxyapatite manufacturers during the forecast period, owing to the rising usage in dental & orthopedic applications.

Hydroxyapatite is one of the building blocks that make tooth enamel, cementum & dentin. It helps in the remineralization of teeth and keeps teeth strong & healthy from enamel erosion & cavities. Hence it is actively being used in dental hygiene products or implants.

Nano-hydroxyapatite, which has crystals that range in size from 50 to 1000 nm, has exciting and soon-to-be-used applications in dentistry, thanks to the recently increasing interest in nanotechnology in numerous sectors.

When present in toothpaste, the nano-hydroxyapatite has a potent affinity for binding to proteins as well as to plaque and bacterial pieces. A study suggests that over 35% of people have untreated dental decay. Fluoride-free alternatives that contain hydroxyapatite have lately been proven to be effective as anti-caries agents.

69% of people between the ages of 35 and 44 have lost one or more permanent teeth due to trauma, gum disease, ineffective root canal therapy, or dental decay, according to data from the American Association of Oral and Maxillofacial Surgeons.

Additionally, at the age of 74, 26% of people had lost every permanent tooth. It follows that there are between 100,000 and 300,000 dental implants used each year. From the abovementioned factors, the dental application is anticipated to reach about USD 331.5 million by the end of 2033.

On the other hand, the orthopedics segment is anticipated to register a CAGR of 7.7% during the forecast period.

Competitive Landscape

The hydroxyapatite industry is fairly consolidated with key players holding a significant share in the market. Key manufacturers are devoted to adopting strategies like investments in R&D, partnerships, collaborations, and acquisitions. They are also signing agreements & contracts with end-use industries for long-term supply of material & to gain more profit.

For instance,

  • In March 2022, CGbio signed a five-year contract worth 10 billion KRW with Kerunxi Medical, a Chinese specializing in dental equipment, for the export of Bongros Dental, a bone graft material made of hydroxyapatite ceramic.
  • In June 2020, CAM Bioceramics announced that it is going to provide restorable ceramics made of hydroxyapatite to Admatec for 3-D printing in Admaflec Printing Systems, which is projected to open the door for Admatec to join the dental care products sector.
  • In October 2020, Allergan Aesthetics, an Abbvie company, acquired Luminera Dermal Filler Business.
  • The Zimmer Biomet Holdings Inc., in March 2022, revealed that the firm concluded its spinoff of ZimVie, which is Zimmer Biomet’s previous spine and dental business.
  • Cgbio entered a five-year contract of value KRW 10 billion with a Chinese firm specializing in dental equipment called Kerunxi Medical in March 2022. The deal is made to export a bone graft material named Bongros Dental.

Scope of Report

Attribute Details
Estimated Market Size (2023) USD 501.8 million
Projected Market Valuation (2033) USD 1,063.5 million
Value-based CAGR (2023 to 2033) 7.8%
Forecast Period 2023 to 2033
Historical Data Available for 2018 to 2022
Market Analysis USD million for Value and Tons for Volume
Key Countries Covered The United States, Canada, Brazil, Mexico, Germany, Italy, France, the United Kingdom, Spain, BENELUX, Russia, China, Japan, South Korea, India, ASEAN, ANZ, GCC Countries, Northern Africa, South Africa
Key Segments Covered Grade, Application, and Region
Key Companies Profiled FLUIDINOVA; SofSera Corporation; Berkeley Advanced Biomaterials; Taihei Chemical Industrial Co. Ltd.; SigmaGraft; CAM Bioceramics; APS Materials, Inc.; Zimmer Biomet; Bioceramics; Granulab (M) Sdn Bhd; Merz Biomaterials; Sangi Co., Ltd.
Report Coverage Market Forecast, Company Share Analysis, Competition Intelligence, DROT Analysis, Market Dynamics and Challenges, and Strategic Growth Initiatives

Hydroxyapatite Market Segmentation

By Grade:

  • Medical Grade
  • Cosmetics Grade
  • Research Grade

By Application:

  • Dental
  • Orthopedic
  • Biochemical Research
  • Surgical
  • Bioceramic Coatings
  • Food
  • Medicine
  • Others

By Region:

  • North America
  • Latin America
  • Europe
  • East Asia
  • South Asia & Pacific
  • Middle East & Africa

Frequently Asked Questions

How big is the hydroxyapatite market?

The hydroxyapatite market is valued at USD 501.8 million in 2023.

Who are the key hydroxyapatite market players?

Some of the key hydroxyapatite market players are CeramTec, Implant Direct and Dentsply Sirona.

Which is the key segment by product type?

Nano-hydroxyapatite is likely to remain preferred through 2033.

Which is the go-to-market strategy?

The players opt for mergers and acquisitions.

Which are the key Asian countries in the hydroxyapatite market?

India, Japan, and China dominate the Asian market.

Table of Content
        1. Executive Summary
        2. Market Overview
        3. Market Background
        4. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033
        5. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Grade
                5.1. Medical Grade
                5.2. Cosmetics Grade
                5.3. Research Grade
        6. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Application
                6.1. Dental
                6.2. Orthopedic
                6.3. Biochemical Research
                6.4. Surgical
                6.5. Bioceramic Coatings
                6.6. Food
                6.7. Medicine
                6.8. Others
        7. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Region
                7.1. North America
                7.2. Latin America
                7.3. Western Europe
                7.4. Eastern Europe
                7.5. South Asia and Pacific
                7.6. East Asia
                7.7. Middle East and Africa
        8. North America Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
        9. Latin America Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
        10. Western Europe Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
        11. Eastern Europe Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
        12. South Asia and Pacific Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
        13. East Asia Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
        14. Middle East and Africa Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
        15. Key Countries Market Analysis
        16. Market Structure Analysis
        17. Competition Analysis
                17.1. FLUIDINOVA
                17.2. SofSera Corporation
                17.3. Berkeley Advanced Biomaterials
                17.4. Taihei Chemical Industrial Co. Ltd.
                17.5. SigmaGraft
                17.6. CAM Bioceramics
                17.7. APS Materials, Inc.
                17.8. Zimmer Biomet
                17.9. Bioceramics
                17.10. Granulab (M) Sdn Bhd
                17.11. Merz Biomaterials
                17.12. Sangi Co., Ltd.
        18. Assumptions & Acronyms Used
        19. Research Methodology
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