Human Milk Oligosaccharide (HMO) Market Outlook from 2024 to 2034

The global human milk oligosaccharide (HMO) market is estimated to reach USD 100.8 million in 2024. Over the forecast period, human milk oligosaccharide sales are poised to increase at a CAGR of 6.5%. The global industry is estimated to reach a value of USD 161.6 million by 2034.

Attributes Key Insights
Estimated Global Human Milk Oligosaccharide (HMO) Market Size (2024E) USD 100.8 million
Projected Human Milk Oligosaccharide (HMO) Market Value (2034F) USD 161.6 million
Value-based CAGR (2024 to 2034) 6.5%

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Global Market Highlights

  • Rising consumer awareness of the value of gut health and increasing demand for dietary supplements are driving the human milk oligosaccharide market growth.
  • Thanks to their antimicrobial and prebiotic properties, HMOs are frequently used in infant formulae, pharmaceuticals, and functional foods.
  • Growth in population, mortality rate, and health-conscious consumers is expected to increase the HMO industry in the future.
  • Rising prevalence of chronic ailments like gut diseases, diabetes, high blood pressure, and rickets drives demand for functional food and beverages, thereby boosting the human milk oligosaccharide market.
  • Infant formula and baby food industries are expected to experience significant growth due to rising demand, surging HMO production, and regulatory approval.
  • Continuous research has resulted in the discovery of new health benefits for specific structures of HMO. This is likely to increase potential applications of HMOs beyond infant nutrition, further boosting the market.

2019 to 2023 Human Milk Oligosaccharide (HMO) Market Growth Outlook

During the historical period, the global sales of human milk oligosaccharide increased steadily, driven by increasing awareness of their health benefits, particularly in infant nutrition. This period observed research and development of alternative methods to extract HMOs from human breast milk, such as microbial fermentation and enzymatic synthesis. These dynamics made it feasible to produce HMOs at scale.

Growing interest in HMOs attracted many investments from established firms and start-ups offering infant nutrition solutions. Additionally, the rising partnerships between companies, research institutions, and universities are facilitating research and product development.

Increased awareness of breastfeeding and human milk components has boosted consumer interest in HMO-containing products. Education initiatives, marketing campaigns, and healthcare professional endorsements are promoting acceptance.

Sales of human milk oligosaccharides are forecasted to expand at a CAGR of 6.5% by 2034. The market is projected to increase in size, thanks to various factors like growing research studies to uncover new health benefits of HMOs.

Extending use of infant nutrition into areas like dietary supplements, and increasing preference given to natural and bioactive ingredients, are likely to drive product demand.

The growth is expected to be fueled by regulatory support and improvements in production technology during the forecast period. Hence, manufacturers are expected to increasingly invest in production capacity expansion, research & development, and marketing efforts. These strategies are likely to enable them to meet the growing demand and exploit the opportunities presented by the expanding HMO market under study.

Nandini Roy Choudhury
Nandini Roy Choudhury

Principal Consultant

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Semi-annual Market Update

Market Statistics Details
Jul to Dec (H2), 2022 (A) 6.8%
Jan to Jun (H1), 2022 (A) 6.2%
Jan to Jun (H1), 2023 Projected (P) 7.3%
Jan to Jun (H1), 2023 Outlook (O) 6.9%
Jan to Jun (H1), 2024 Projected (P) 10.0%
Jul to Dec (H2), 2023 Outlook (O) 9.1%
Jul to Dec (H2), 2023 Projected (P) 8.8%

Key Human Milk Oligosaccharide (HMO) Market Trends

  • Increasing demand for HMOs in infant nutrition due to their role in mimicking the benefits of breast milk
  • Expansion of research into novel HMO structures and their potential health benefits
  • Rising interest in HMO supplementation for preterm infants to support gut health and immune function
  • Growing partnerships between HMO suppliers and infant formula manufacturers to enhance product offerings
  • Development of HMO-based functional foods for adults targeting gut health and immune support
  • Increasing investment in HMO production technologies to meet growing demand
  • Regulatory advancements to establish standards and guidelines for HMO supplementation in infant formula
  • Emergence of personalized nutrition solutions incorporating HMOs based on individual health needs and microbiome profiles

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Restraining Factors in Human Milk Oligosaccharide (HMO) Market

  • The complex and costly production of HMOs, especially through chemical or enzymatic methods, is set to hinder widespread adoption, particularly in cost-sensitive markets or regions with limited resources.
  • Regulatory approval of novel food ingredients is usually lengthy and complex for any new food additive, including HMOs. This could prolong product development or create uncertainties about the prospects of market entry.
  • HMOs, naturally found in human milk, are hard to procure from any other source due to scalability and yield optimization issues, which may hinder the growth of this market or the availability of more HMO-fortified products.

Country-wise Insights

The table below shows the estimated growth rates of the leading countries. The United Kingdom, China, and Germany are set to record high CAGRs of 6.2%, 5.5%, and 5.9%, respectively, through 2034.

Countries CAGR
United States 4.5%
United Kingdom 6.2%
Germany 5.9%
China 5.5%
Japan 4.8%

Research and Development Activities in the United States Upscaling the Market

The United States is expected to exhibit a CAGR of 4.5% through 2034. Key factors supporting the market growth are:

The United States has a developed infrastructure for research and development, resulting in innovation in infant nutrition, which is driving market growth. The baby formula market in the United States is on the rise due to increasing awareness about breastfeeding and early nutrition benefits. It is largely driven by parents demanding products that resemble human breast milk.

Many corporate houses and several academic institutions across the country are involved with HMO-related research and development projects. These projects concentrate on enhancing production techniques, investigating novel uses, and comprehending the health advantages of HMOs in newborn nutrition.

Increasing Government Initiatives to Surge Sales in China

During the forecast period, China is expected to expand at a CAGR of 5.5%. HMO-infused premium baby nutrition products are expected to be driven by factors like rising disposable income and urbanization in China.

Increasing initiatives by the government of China to promote breastfeeding and regulate infant formula standards are encouraging the use of HMO in infant formula. Further, Chinese players are into fostering collaborations between academic institutions, research facilities, and industry players to increase their stake.

Increasing Digestive Disorders Among Japanese Consumers Propel Product Demand

The demand for human milk oligosaccharides in Japan is anticipated to steadily increase at a CAGR of 4.8% during the forecast period. The rising incidences of digestive disorders and food sensitivities among infants are pushing the sales of HMOs in Japan.

Additionally, consumer knowledge of HMOs is increasing due to rising marketing campaigns, educational initiatives, and healthcare industry endorsements. This is boosting the product’s acceptance among parents and caregivers. This is projected to accelerate product sales in the nation.

Category-wise Insights

The section below shows the fucosylated segment dominating by product type. The segment is predicted to reach USD 42.9 million in 2034. Based on end-use, the infant formula segment is anticipated to generate a dominant share through 2024. It is set to reach USD 99.2 million by 2024.

Segment Infant Formula (End-use)
Market Value (2024) USD 99.2 million

Demand for Human Milk Oligosaccharides to Remain High in Infant Formula

Infant formula mimics breast milk's composition to provide effective nutrients to non-breastfed infants. By virtue of their role in gut health, immune function, and development, HMOs found in breast milk are crucial to be included in infant formulations for similar benefits. The use of HMOs in infant formulations is increasing due to strict regulatory standards, making HMOs a popular choice for infant health supplements.

Fucosylated HMOs Segment Tops the Product Type Category

Segment Fucosylated (Product Type)
Market Value (2034) USD 42.9 million

Fucosylated HMOs, like 2'-fucosyllactose and 3-fucosyllactose, are gaining traction as they are crucial for infant gut health. These also help in promoting beneficial bacteria growth and inhibiting pathogen adhesion.

Since they are the closest to human breast milk in mimicking their health benefits, manufacturers take an interest in fucosylated HMOs. They are projected to contribute to the development of a healthy gut microbiome essential for immune function and nutrient absorption.

Competitive Landscape

The human milk oligosaccharide (HMO) market remains extremely dynamic and highly competitive. In line with this, key companies in the industry participate in research & development, new formulation, and sustainable sourcing to further capture markets.

Key players are focusing on obtaining product certifications, following environmentally friendly practices, and meeting the increased demand for natural ingredients and sustainability.

For instance

  • In 2021, BASF announced that the Australian TGA had approved the 2’-FL brand of PREBILAC. This approval establishes PREBILAC as the initial and exclusive 2’-FL ingredient to receive recognition from TGA as a prebiotic ingredient.
  • In 2022, Kyowa Hakko Bio Co. Ltd, a subsidiary of Kirin Holdings Company Limited, finalized the construction of a manufacturing facility. It is dedicated to the production of human milk oligosaccharides (HMOs) at its Thai subsidiary, Thai Kyowa Biotechnologies Co, Ltd.

Key Companies Profiled

  • Jennewein Biotechnologie GmbH
  • KYOWA HAKKO BIO CO. LTD.
  • DSM
  • Nestle Health Science
  • DUPONT
  • zuChem Inc.
  • Glycosyn LLC
  • Elicityl SA
  • Dextra Laboratories Limited
  • Carbosynth Limited

Key Coverage in the Global Human Milk Oligosaccharide Industry Research Report

  • Adjacent Study on Human Milk Oligosaccharides Benefits and Nutritional Products Human Milk Oligosaccharides
  • Detailed Market Analysis of Human Milk Oligosaccharides Supplement
  • Ongoing Innovations in Human Milk Oligosaccharides Formula
  • Growth Prospects for Baby Food Market in the United States
  • Top Players in Baby Food and Infant Formula Market
  • Human Milk Oligosaccharides and Immune System Development

Human Milk Oligosaccharide (HMO) Market Segmentation by Category

By Product Type:

  • Fucosylated
    • 2FL
    • 2FL DFL
    • 3FL
  • Silylated
    • 3SL
    • 6SL
  • Non-fucosylated Neutral
    • LNT
    • LNnT
    • LNFP

By End-use:

  • Infant Formula
  • Dietary Supplements

By Region:

  • North America
  • Latin America
  • Europe
  • South Asia
  • East Asia
  • Middle East and Africa
  • Oceania

Frequently Asked Questions

How big is the human milk oligosaccharide market?

The market is set to reach USD 100.8 million in 2024.

What is the forecast for the human milk oligosaccharide market?

Demand for human milk oligosaccharide is slated to expand at a 6.5% CAGR by 2034.

What is the outlook for the human milk oligosaccharide market?

The market is set to reach USD 161.6 million in 2034.

Who are the key players in the human milk oligosaccharide market?

KYOWA HAKKO BIO CO. LTD., DSM, and Nestle Health Science are the key players.

Which product type would lead the human milk oligosaccharide market?

Fucosylated segment is estimated to hold a significant market share in 2024.

Which region is expected to hold the leading market share by 2034?

Asia Pacific is expected to hold a market share of 39.2% by 2034.

Table of Content

1. Executive Summary

    1.1. Global Market Outlook

    1.2. Demand Side Trends

    1.3. Supply Side Trends

    1.4. Technology Roadmap

    1.5. Analysis and Recommendations

2. Market Overview

    2.1. Market Coverage / Taxonomy

    2.2. Market Definition

3. Market Dynamics

    3.1. Drivers

        3.1.1. Supply Side Drivers

        3.1.2. Demand Side drivers

        3.1.3. Economic Side Drivers

    3.2. Restraints

    3.3. Opportunity

    3.4. Market trends By Region

    3.5. Forecast Factors - Relevance & Impact

    3.6. Key Regulations and Policies

4. Value Chain Analysis

    4.1. Operating Margins at Each Node of the Supply Chain

    4.2. List of Active Market Participants

5. Global - Pricing Analysis

    5.1. Price Point Assessment by Region

        5.1.1. Manufacturer-Level Pricing

        5.1.2. Distributor Level Pricing

    5.2. Price Point Assessment By Product

    5.3. Price Forecast till 2034

6. Global Market Size (in Value (US$ million) and Volume (MT) Analysis 2019 to 2023 and Forecast, 2024 to 2034

    6.1. Historical Market Size (in Value (US$ million) and Volume (MT) Analysis, 2019 to 2023

    6.2. Current and Future Market Size (in Value (US$ million) and Volume (MT) Analysis, 2024 to 2034

        6.2.1. Y-o-Y Growth Trend Analysis

        6.2.2. Absolute $ Opportunity Analysis

7. Global Market Analysis 2019 to 2023 and Forecast 2024 to 2034, By Product Type

    7.1. Introduction / Key Findings

    7.2. Historical Market Size (in Value (US$ million) and Volume (MT) Analysis By Product Type, 2019 to 2023

    7.3. Current and Future Market Size (in Value (US$ million) and Volume (MT) Analysis and Forecast By Product Type, 2024 to 2034

        7.3.1. Fucosylated

            7.3.1.1. 2FL

            7.3.1.2. 2FL DFL

            7.3.1.3. 3FL

        7.3.2. Silylated

            7.3.2.1. 3SL

            7.3.2.2. 6SL

        7.3.3. Non-fucosylated Neutral

            7.3.3.1. LNT

            7.3.3.2. LNnT

            7.3.3.3. LNFP

    7.4. Market Attractiveness Analysis By Product Type

8. Global Market Analysis 2019 to 2023 and Forecast 2024 to 2034, By End-use

    8.1. Introduction / Key Findings

    8.2. Historical Market Size (in Value (US$ million) and Volume (MT) Analysis By End-use, 2019 to 2023

    8.3. Current and Future Market Size (in Value (US$ million) and Volume (MT) Analysis and Forecast By End-use, 2024 to 2034

        8.3.1. Infant Formula

        8.3.2. Dietary Supplements

    8.4. Market Attractiveness Analysis By End-use

9. Global Market Analysis 2019 to 2023 and Forecast 2024 to 2034, by Region

    9.1. Introduction

    9.2. Historical Market Size (in Value (US$ million) and Volume (MT) Analysis By Region, 2019 to 2023

    9.3. Current Market Size (in Value (US$ million) and Volume (MT) Analysis and Forecast By Region, 2024 to 2034

        9.3.1. North America

        9.3.2. Latin America

        9.3.3. Europe

        9.3.4. East Asia

        9.3.5. South Asia

        9.3.6. Oceania

        9.3.7. Middle East and Africa

    9.4. Market Attractiveness Analysis By Region

10. North America Market Analysis 2019 to 2023 and Forecast 2024 to 2034

    10.1. Introduction

    10.2. Historical Market Size (US$ million) and Volume Trend Analysis By Market Taxonomy, 2019 to 2023

    10.3. Market Size (US$ million) and Volume Forecast By Market Taxonomy, 2024 to 2034

        10.3.1. By Country

            10.3.1.1. United States

            10.3.1.2. Canada

        10.3.2. By Product Type

        10.3.3. By End-use

    10.4. Market Attractiveness Analysis

        10.4.1. By Country

        10.4.2. By Product Type

        10.4.3. By End-use

    10.5. Key Takeaways

11. Latin America Market Analysis 2019 to 2023 and Forecast 2024 to 2034

    11.1. Introduction

    11.2. Historical Market Size (US$ million) and Volume Trend Analysis By Market Taxonomy, 2019 to 2023

    11.3. Market Size (US$ million) and Volume Forecast By Market Taxonomy, 2024 to 2034

        11.3.1. By Country

            11.3.1.1. Brazil

            11.3.1.2. Mexico

            11.3.1.3. Argentina

            11.3.1.4. Rest of Latin America

        11.3.2. By Product Type

        11.3.3. By End-use

    11.4. Market Attractiveness Analysis

        11.4.1. By Country

        11.4.2. By Product Type

        11.4.3. By End-use

    11.5. Key Takeaways

12. Europe Market Analysis 2019 to 2023 and Forecast 2024 to 2034

    12.1. Introduction

    12.2. Historical Market Size (US$ million) and Volume Trend Analysis By Market Taxonomy, 2019 to 2023

    12.3. Market Size (US$ million) and Volume Forecast By Market Taxonomy, 2024 to 2034

        12.3.1. By Country

            12.3.1.1. Germany

            12.3.1.2. United Kingdom

            12.3.1.3. France

            12.3.1.4. Italy

            12.3.1.5. Spain

            12.3.1.6. BENELUX

            12.3.1.7. Nordic

            12.3.1.8. Russia

            12.3.1.9. Poland

            12.3.1.10. Rest of Europe

        12.3.2. By Product Type

        12.3.3. By End-use

    12.4. Market Attractiveness Analysis

        12.4.1. By Country

        12.4.2. By Product Type

        12.4.3. By End-use

    12.5. Key Takeaways

13. East Asia Market Analysis 2019 to 2023 and Forecast 2024 to 2034

    13.1. Introduction

    13.2. Historical Market Size (US$ million) and Volume Trend Analysis By Market Taxonomy, 2019 to 2023

    13.3. Market Size (US$ million) and Volume Forecast By Market Taxonomy, 2024 to 2034

        13.3.1. By Country

            13.3.1.1. China

            13.3.1.2. Japan

            13.3.1.3. South Korea

        13.3.2. By Product Type

        13.3.3. By End-use

    13.4. Market Attractiveness Analysis

        13.4.1. By Country

        13.4.2. By Product Type

        13.4.3. By End-use

    13.5. Key Takeaways

14. South Asia Market Analysis 2019 to 2023 and Forecast 2024 to 2034

    14.1. Introduction

    14.2. Historical Market Size (US$ million) and Volume Trend Analysis By Market Taxonomy, 2019 to 2023

    14.3. Market Size (US$ million) and Volume Forecast By Market Taxonomy, 2024 to 2034

        14.3.1. By Country

            14.3.1.1. India

            14.3.1.2. Thailand

            14.3.1.3. Malaysia

            14.3.1.4. Indonesia

            14.3.1.5. Singapore

            14.3.1.6. Vietnam

            14.3.1.7. Philippines

            14.3.1.8. Rest of South Asia

        14.3.2. By Product Type

        14.3.3. By End-use

    14.4. Market Attractiveness Analysis

        14.4.1. By Country

        14.4.2. By Product Type

        14.4.3. By End-use

    14.5. Key Takeaways

15. Oceania Market Analysis 2019 to 2023 and Forecast 2024 to 2034

    15.1. Introduction

    15.2. Historical Market Size (US$ million) and Volume Trend Analysis By Market Taxonomy, 2019 to 2023

    15.3. Market Size (US$ million) and Volume Forecast By Market Taxonomy, 2024 to 2034

        15.3.1. By Country

            15.3.1.1. Australia

            15.3.1.2. New Zealand

        15.3.2. By Product Type

        15.3.3. By End-use

    15.4. Market Attractiveness Analysis

        15.4.1. By Country

        15.4.2. By Product Type

        15.4.3. By End-use

    15.5. Key Takeaways

16. Middle East and Africa Market Analysis 2019 to 2023 and Forecast 2024 to 2034

    16.1. Introduction

    16.2. Historical Market Size (US$ million) and Volume Trend Analysis By Market Taxonomy, 2019 to 2023

    16.3. Market Size (US$ million) and Volume Forecast By Market Taxonomy, 2024 to 2034

        16.3.1. By Country

            16.3.1.1. GCC Countries

            16.3.1.2. Turkiye

            16.3.1.3. Egypt

            16.3.1.4. South Africa

            16.3.1.5. Rest of Middle East and Africa

        16.3.2. By Product Type

        16.3.3. By End-use

    16.4. Market Attractiveness Analysis

        16.4.1. By Country

        16.4.2. By Product Type

        16.4.3. By End-use

    16.5. Key Takeaways

17. Country-level Market Analysis, 2022

    17.1. United States Market Analysis

        17.1.1. By Product Type

        17.1.2. By End-use

    17.2. Canada Market Analysis

        17.2.1. By Product Type

        17.2.2. By End-use

    17.3. Brazil Market Analysis

        17.3.1. By Product Type

        17.3.2. By End-use

    17.4. Mexico Market Analysis

        17.4.1. By Product Type

        17.4.2. By End-use

    17.5. Argentina Market Analysis

        17.5.1. By Product Type

        17.5.2. By End-use

    17.6. Germany Market Analysis

        17.6.1. By Product Type

        17.6.2. By End-use

    17.7. United Kingdom Market Analysis

        17.7.1. By Product Type

        17.7.2. By End-use

    17.8. France Market Analysis

        17.8.1. By Product Type

        17.8.2. By End-use

    17.9. Italy Market Analysis

        17.9.1. By Product Type

        17.9.2. By End-use

    17.10. Spain Market Analysis

        17.10.1. By Product Type

        17.10.2. By End-use

    17.11. Belgium Market Analysis

        17.11.1. By Product Type

        17.11.2. By End-use

    17.12. Netherlands Market Analysis

        17.12.1. By Product Type

        17.12.2. By End-use

    17.13. Nordic Market Analysis

        17.13.1. By Product Type

        17.13.2. By End-use

    17.14. Russia Market Analysis

        17.14.1. By Product Type

        17.14.2. By End-use

    17.15. Poland Market Analysis

        17.15.1. By Product Type

        17.15.2. By End-use

    17.16. China Market Analysis

        17.16.1. By Product Type

        17.16.2. By End-use

    17.17. Japan Market Analysis

        17.17.1. By Product Type

        17.17.2. By End-use

    17.18. South Korea Market Analysis

        17.18.1. By Product Type

        17.18.2. By End-use

    17.19. India Market Analysis

        17.19.1. By Product Type

        17.19.2. By End-use

    17.20. Thailand Market Analysis

        17.20.1. By Product Type

        17.20.2. By End-use

    17.21. Malaysia Market Analysis

        17.21.1. By Product Type

        17.21.2. By End-use

    17.22. Vietnam Market Analysis

        17.22.1. By Product Type

        17.22.2. By End-use

    17.23. Philippines Market Analysis

        17.23.1. By Product Type

        17.23.2. By End-use

    17.24. Indonesia Market Analysis

        17.24.1. By Product Type

        17.24.2. By End-use

    17.25. Singapore Market Analysis

        17.25.1. By Product Type

        17.25.2. By End-use

    17.26. Australia Market Analysis

        17.26.1. By Product Type

        17.26.2. By End-use

    17.27. New Zealand Market Analysis

        17.27.1. By Product Type

        17.27.2. By End-use

    17.28. GCC Countries Market Analysis

        17.28.1. By Product Type

        17.28.2. By End-use

    17.29. Turkiye Market Analysis

        17.29.1. By Product Type

        17.29.2. By End-use

    17.30. Egypt Market Analysis

        17.30.1. By Product Type

        17.30.2. By End-use

    17.31. South Africa Market Analysis

        17.31.1. By Product Type

        17.31.2. By End-use

18. Market Structure Analysis

    18.1. Global Competition - a Dashboard View

    18.2. Industry Structure Analysis

        18.2.1. % tier 1 market players

        18.2.2. % tier 2 market players

        18.2.3. % tier 3 market players

    18.3. Global Market Company Share Analysis

        18.3.1. For Tier 1 Market Players, 2024

        18.3.2. Company Market Share Analysis of Top 5 Players, By Region

    18.4. Key Participants Market Presence (Intensity Mapping) by Region

19. Competition Analysis

    19.1. Competition Dashboard

    19.2. Competition Benchmarking

    19.3. Competition Deep Dive

        19.3.1. Jennewein Biotechnologie GmbH

            19.3.1.1. Product Portfolio

            19.3.1.2. Product Claim

            19.3.1.3. Revenue by Market Segments (Product/ channel/Region)

            19.3.1.4. Sales Footprint

            19.3.1.5. Strategy Overview

                19.3.1.5.1. Marketing Strategy

                19.3.1.5.2. Product Strategy

                19.3.1.5.3. Channel Strategy

            19.3.1.6. SWOT Analysis

        19.3.2. KYOWA HAKKO BIO CO. LTD.

        19.3.3. DSM

        19.3.4. Nestle Health Science

        19.3.5. DUPONT

        19.3.6. zuChem Inc.

        19.3.7. Glycosyn LLC

        19.3.8. Elicityl SA

        19.3.9. Dextra Laboratories Limited

        19.3.10. Carbosynth Limited

        19.3.11. Other Players (On Additional Requests)

20. Assumptions and Acronyms Used

21. Research Methodology

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December 2014

REP-GB-SA-28

57 pages

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