HLA Typing Market Outlook 2023 to 2033

Current estimations indicate that the global HLA typing market is valued at USD 1.1 billion. The market is expected to grow at a modest rate of 6.7% between 2023 and 2033. By 2033, the market valuation is projected to reach USD 2.1 billion.

Key Market Highlights

The Rising Amount of Transplant Treatments Boosts Demand for The HLA Typing Market

The global HLA typing market is expected to experience growth due to the rise in organ transplants, the increasing prevalence of chronic and infectious diseases, and advancements in the molecular assays used for HLA typing. The availability of funding for HLA typing research is another factor likely to impact the market positively. Additionally, increasing public awareness regarding organ donations presents an opportunity for the HLA typing market to expand.

Attributes Key Statistics
Expected Base Year Value (2023) USD 1.1 billion
Anticipated Forecast Value (2033) USD 2.1 billion
Estimated Growth (2023 to 2033) 6.7% CAGR

Despite the importance of molecular assays in HLA typing, their high costs remain a significant challenge for the HLA typing market. Additionally, the gap between the number of organs required for transplantation and the number of available organ donations presents a substantial obstacle for the HLA typing market.

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Growing Technological Innovations in HLA Typing Platforms has Witnessed the Market Growth

The diagnostic techniques for HLA typing have shifted from serology-based to genome-based procedures due to the development of PCR-based genome sequencing that is now integrated with microfluidics, biomedical instrumentation, and robotics.

The ongoing technological advancements in HLA typing have led to higher sample throughput, increased device sensitivity, early detection of incompatibility, and improved procedural efficacy compared to serological techniques. As a result of these benefits, the demand for HLA typing products has increased among significant end users such as research laboratories, hospitals, transplant centers, and diagnostic laboratories.

Several market players have expanded and commercialized PCR and NGS-based HLA typing reagents for detecting genetic modifications and determining precise HLA alleles. Efforts by the market players to boost the healthcare industry, coupled with rising disposable incomes worldwide, have also contributed to the industry's growth.

Historical Analysis of the HLA Typing Market

The need for transplantation procedures has proliferated in recent years, particularly for diseases like blood cancers and genetic blood disorders that require stem cell transplantation. Increased public awareness of organ transplantation and supportive regulations from regulatory authorities have further propelled the market forward.

As the number of transplant procedures continues to rise worldwide, the market is expected to experience significant growth in the forecasted period.

Several hospitals and market players are focusing on developing health infrastructure to reduce disease burden and improve healthcare services. Additionally, the increasing adoption of advanced medical devices, transplant treatments, and other therapies is creating favorable growth opportunities for the market throughout the forecast period.

Attributes Key Statistics
Expected Base Year Value (2022) USD 1.0 billion
Final Value (2033) USD 2.1 billion
Estimated Growth (2018 to 2022) 8.2% CAGR
Sabyasachi Ghosh
Sabyasachi Ghosh

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Consumption Analysis of the HLA Typing Market

  • The demand for HLA testing is increasing as it finds usage in multiple applications. Integrating HLA typing in personalized immunotherapy is a significant advancement and is expected to be a breakthrough in the field. This integration can help HLA testing professionals fill global gaps in human leukocyte antigen libraries and identify HLA variants associated with diseases. Advancements in this area can further improve the accuracy of HLA typing for vaccine design and organ transplants.
  • In the forecasted period, the most significant technology segment in the human leukocyte antigen (HLA) typing for transplant market is represented by molecular assays. This is due to the advantages provided by molecular assays, including high procedural efficacy, real-time sample analysis, low turnaround time, and the ability to analyze multiple samples.
  • The incorporation of HLA typing in personalized immunotherapy is a significant advancement that can aid HLA testing professionals in filling gaps in human leukocyte antigen libraries worldwide and identifying human leukocyte antigen variants in diseases. Additionally, progress in this field may improve HLA typing accuracy for organ transplants and vaccine development.
  • Over a while, the procedure of screening the donor and recipient involved using serology-based assays before undergoing a transplantation procedure. However, gene-based histocompatibility testing methods are preferred to serology-based assays. The molecular assay takes less time for analysis, has higher sample throughput, can handle several samples in a single run, and requires fewer patient samples than serology assay techniques. As a result, the adoption of molecular assay technologies for HLA profiling in transplant donor patients is increasing.

Top Product Type Insights

Increasing Prevalence of Instruments in Transplantation is Driving the HLA Typing Market

The global HLA typing market has three categories based on the type of products - instruments, reagents and consumables, and software and services. The instruments segment is perfect for organ transplantation procedures of the vital organs.

The instruments segment held a CAGR of 8.0% from 2018 to 2022. The software and services segment is anticipated to catch up to the instruments segment in terms of value as organ transplantation, disease diagnosis, and personalized medicines expand during the research period. In the upcoming decade, the instruments segment has been supposed to dominate the market, according to a global CAGR of 6.5%.

Top Product Instruments
CAGR % 2018 to 2022 8.0% CAGR
CAGR % 2023 to End of Forecast (2033) 6.5% CAGR

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Top Application Insights

Diagnostics Segment Accounted for the Highest Market Share With A CAGR of 7.7%

During the forecast period, the global HLA typing transplant market is segmented into diagnostics and research, with the diagnostics segment accounting for a leading market share in 2022, with a CAGR of 7.7%. This can be attributed to the trend among hospitals and transplant centers to outsource laboratory services, as well as the increase in diagnostics laboratories merging.

Hospitals and transplant centers collaborate with diagnostic labs to perform diagnostic tests that can diagnose diseases such as Behcet's disease, rheumatoid arthritis, and narcolepsy, which can accelerate the market for HLA typing. The research segment is expected to experience significant growth during the forecast period.

Top Application Diagnosis
CAGR % 2018 to 2022 7.7% CAGR
CAGR % 2023 to End of Forecast (2033) 6.3% CAGR

Country-wise Insights

Expansion of the HLA Typing Market Across the United States

The HLA typing market in the United States generated revenue of USD 360.7 million in 2033. The market may grow significantly in the coming years, with an expected CAGR of 6.9% from 2023 to 2033. The United States dominates the market due to the rise in demand for organ transplants and the government's support to encourage growth in programs for organ donation and transplantation.

Country United States
CAGR (2018 to 2022) 8.7%
CAGR (2023 to 2033) 6.9%

Surging Demand for HLA Typing Procedures in the United Kingdom

The United Kingdom is expected to dominate the market growth during the forecast period, thanks to the high adoption of advanced technologies and the increasing prevalence of the disease. These factors are expected to drive the development of the regional market in the United Kingdom. The HLA typing market in the United Kingdom is anticipated to deliver a market share of 69.3 million with a CAGR of 5.8% in the upcoming decade.

Country United Kingdom
CAGR (2018 to 2022) 6.6%
CAGR (2023 to 2033) 5.8%

Pivotal Role of China in the Advanced HLA Typing Market

By 2023, the HLA typing industry in China is expected to experience a significant growth rate of 9.5%. The demand for HLA typing is predicted to continuously increase, with a compound annual growth rate of 7.1% over the next ten years. This growth is attributed to the improved infrastructure of healthcare facilities, expanding economic factors, and well-designed reimbursement policies, which are having a positive impact on the development of the market.

Country China
CAGR (2018 to 2022) 9.5%
CAGR (2023 to 2033) 7.1%

Japan Considerably Holds a Lucrative Position in the HLA Typing Market

In the upcoming years, the market for HLA typing in Japan is expected to experience significant growth. This is attributed to the development of technical and healthcare sectors in producing provinces. It is anticipated that the demand for HLA typing in Japan is likely to register a growth of 7.6% between 2023 and 2033. The healthcare sector's growing demand for HLA typing is expected to propel market growth in the next decade.

Country Japan
CAGR (2018 to 2022) 9.3%
CAGR (2023 to 2033) 6.5%

The Dominance of the HLA Typing Technology in South Korea

The market for HLA typing in South Korea is expected to evolve rapidly in the coming years. This is due to the development of the technical and healthcare sectors in developing provinces. The demand for HLA typing in South Korea is projected to record a CAGR of around 4.7% from 2023 to 2033. The healthcare sector's increasing need for HLA typing is expected to drive market growth in the next decade.

Country South Korea
CAGR (2018 to 2022) 5.2%
CAGR (2023 to 2033) 4.7%

Competitive Landscape in the HLA Typing Market

HLA typing is increasingly essential in healthcare, providing benefits such as improved outcomes in organ transplantation, personalized medicine, better diagnosis and treatment of diseases, and scientific research opportunities. Key players in the market include Thermo Fisher Scientific Inc., Bio-Rad Laboratories Inc., Qiagen N.V., Omixon Inc., GenDx, and Illumina Inc., which use organic and inorganic growth strategies to expand their consumer base.

Recent Developments in the HLA Typing Market

  • Eurobio Scientific's GenDx subsidiary launched NGS-Turbo in October 2023. It utilizes Oxford Nanopore Technologies sequencing devices for Research Use Only (RUO) and offers unmatched speed and efficiency for HLA typing when time is crucial.
  • Omixon, Inc. introduced the NanoTYPE RUO Multiplex Human Leukocyte Antigen Amplification kit, which is now compatible with the MinION Platform developed by Oxford Nanopore, in September of 2023.
  • In April 2023, Metropolis Healthcare revealed the NextGen HLA test for organ transplantation. Next-generation sequencing (NGS) technology will improve the percentage of Human Leukocyte Antigen (HLA) matches between donor and recipient.
  • In March 2023, BioRad received AOAC international and AFNOR approval for its iO-Check kits, which are used with the CFX Opus Deepwell Real-time PCR System.
  • In May 2022, CareDx received CE marking for its AlloSeq HCT chimerism testing kit and AlloSeq HCT software. These AlloSeq are functioned in patients who have acquired Hematopoietic cell transplantation.
  • In January 2020, GenDx partnered with Berlin-based PIRCHE AG and released a new version of NGSengine, its HLA typing program. The latest version can export individual HLA typing data to PIRCHE's matching services website. The integration will provide more accurate HLA typing data to researchers and clinicians.

Key Companies in the HLA Typing Market

  • Thermo Fisher Scientific Inc.
  • Bio-Rad Laboratories Inc.
  • Qiagen N.V.
  • Omixon Inc.
  • GenDx
  • Illumina Inc.
  • F.Hoffmann-La Roche Ltd.
  • Immucor, Inc.
  • bioMerieux S.A.
  • CareDx, Inc.
  • Hologic, Inc.
  • Olerup International AB

Market Segmentation

By Product Type:

  • Instruments
  • Reagents & Consumables
  • Software & Services

By Application:

  • Diagnosis
  • Research

By Technique:

  • Molecular Assay
  • Sequenced-based Molecular Assay
  • Non-molecular Assay

By End User:

  • Commercial Service Providers
  • Hospitals
  • Transplant Centers
  • Research Labs
  • Academic Institutes

By Region:

  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • The Middle East & Africa

Frequently Asked Questions

What was the Global HLA Typing Market Size in 2022?

The HLA typing market was valued at USD 1.0 billion in 2022.

What Big is the HLA Typing Market in 2023?

In 2023, the global HLA typing market is likely to reach USD 1.1 billion.

What CAGR did the HLA Typing Market Exhibit over the Last Four Years?

The HLA typing market exhibited an 8.2% CAGR over the last four years.

What is the Growth Potential of the Global HLA Typing Market?

The market is anticipated to expand at a CAGR of 6.7% from 2023 to 2033.

Which Product is Dominating the HLA Typing Market?

The instrument products are dominating the market with a CAGR of 8.0%.

Table of Content
	1. Executive Summary
	2. Market Overview
	3. Market Background
	4. Global Market Analysis 2018 to 2022 and Forecast, 2023 to 2033
	5. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Product
		5.1. Instruments
		5.2. Reagents & Consumables
		5.3. Software & Services
	6. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Application
		6.1. Diagnosis
		6.2. Research
	7. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Technique
		7.1. Molecular Assay
		7.2. Sequenced-based Molecular Assay
		7.3. Non-Molecular Assay
	8. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By End-user
		8.1. Commercial Service Providers
		8.2. Hospitals and Transplant Centers
		8.3. Research Labs & Academic Institutes
	9. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Region
		9.1. North America
		9.2. Latin America
		9.3. Western Europe
		9.4. Eastern Europe
		9.5. South Asia and Pacific
		9.6. East Asia
		9.7. Middle East and Africa
	10. North America Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
	11. Latin America Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
	12. Western Europe Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
	13. Eastern Europe Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
	14. South Asia and Pacific Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
	15. East Asia Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
	16. Middle East and Africa Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
	17. Key Countries Market Analysis
	18. Market Structure Analysis
	19. Competition Analysis
		19.1. Thermo Fisher Scientific Inc.
		19.2. Bio-Rad Laboratories Inc.
		19.3. Qiagen N.V.
		19.4. Omixon Inc.
		19.5. GenDx
		19.6. Illumina Inc.
		19.7. TBG Diagnostics Limited
		19.8. Dickinson and Company
		19.9. Takara Bio Inc.
		19.10. F. Hoffman-La Roche Limited
		19.11. Pacific Biosciences
	20. Assumptions & Acronyms Used
	21. Research Methodology
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