Genome Editing Market Outlook from 2024 to 2034

The genome editing is expected to be valued at USD 6.2 billion in 2024. Genome editing is projected to grow at a moderate CAGR of 15.7% from 2024 to 2034. The global genome editing market size is predicted to reach USD 26.5 billion by 2034.

Attributes Key Insights
Estimated Market Size in 2024 USD 6.2 billion
Projected Market Value in 2034 USD 26.5 billion
Value-based CAGR from 2024 to 2034 15.7%

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Key Market Trends and Highlights

  • Research and commercialization have been made more predictable through the establishment of regulatory frameworks and guidelines.
  • Genome editing technologies can be translated from the laboratory to the clinic with regulatory support.
  • Gene function and regulation are continually being explored through ongoing research and discoveries in genomics.
  • Genome editing technologies in human germline editing became increasingly controversial as genome editing technologies advanced.
  • AI and machine learning have been integrating rapidly into genome editing research. CRISPR designs were optimized using these technologies, resulting in faster experimentation by analyzing large genomic datasets and predicting off-target effects.

2019 to 2023 Historical Analysis vs. 2024 to 2034 Market Forecast Projections

Genome editing accounted for 18.4% CAGR from 2019 to 2023. Genome editing tools continue to advance in their delivery methods. The efficiency and safety of CRISPR editing were being improved by developing new and improved methods of delivering CRISPR components to target cells.

Personalized and targeted gene therapies for cancer are being explored using genome editing. Cancer cells can be targeted and destroyed by immune cells that have been enhanced to target and destroy them by scientists.

A growing emphasis was placed on public awareness and engagement as genome editing technologies gained traction. In addition to exploring the potential benefits and risks of gene editing, there was also a conversation about the ethical implications. A 15.7% CAGR is forecast between 2024 and 2034.

Historical CAGR from 2019 to 2023 18.4%
Forecast CAGR from 2024 to 2034 15.7%

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Genome Editing Drivers

  • Genome editing technologies are becoming more popular as genetic diseases and disorders increase. The development of potential therapies for genetic conditions is an active field of research among researchers and pharmaceutical companies.
  • Increased investments in biotechnology and healthcare have supported the development and commercialization of genome editing technologies. By providing funding, researchers can conduct studies, conduct clinical trials, and develop medical solutions based on laboratory findings.
  • Customizing treatments to each individual's genetic makeup is one of the most important contributions of genome editing to personalized medicine. Treatment efficacy can be enhanced, while this approach can minimize side effects.
  • Genetic engineering in agriculture is being used to develop more nutritious crops that are resistant to pests and diseases and increase yield. Food security and sustainable agriculture can be improved through this application.

Genome Editing Challenges

  • CRISPR-Cas9, especially, offers the potential for off-target effects, which is one of the major challenges in genome editing. Preventing unintended changes to the genome and ensuring precision in editing remain important challenges.
  • A significant ethical concern has been raised about genome editing, especially regarding human germline editing. Designer babies and inheritable genetic changes are still being debated for their potential unintended consequences and long-term effects.
  • Therapeutic applications of genome editing, particularly in vivo delivery, remain challenging. For genome editing to succeed, delivery methods must be optimized while off-target effects are minimized.
  • In the case of viral vectors, the immune system had a hard time responding to genome editing components. Research is going on to overcome or mitigate immune responses that could impact editing efficacy and safety.

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Country-wise Analysis

According to the table provided, South Korea and the United Kingdom have the highest gene editing market revenue. As genome editing technology develops, it will significantly impact the future of the market.

Biological parts, devices, and systems can be designed and constructed through synthetic biology. This technology enables the development of new gene-editing methods and tools, expanding the application possibilities of genome editing.

Gene-editing tools can be delivered to target cells with increased precision using nanotechnology. Genome editing can be more efficient and safer by engineered nanoparticles that carry gene-editing components.

Countries Forecast CAGRs from 2024 to 2034
The United States 15.9%
China 16.2%
Japan 16.5%
South Korea 17.8%
The United Kingdom 17.1%

Stringent regulations may drive demand for genome editing in the United States

A high demand for genome editing is expected in the United States. A CAGR of 15.9% is forecast for the market during the period. Regulatory scrutiny of genome editing technologies, particularly those that may be applied to human therapeutic applications, has been conducted by agencies such as the Food and Drug Administration (FDA).

The United States witnessed several ongoing ethical debates, especially regarding the use of germline editing, as well as the use of genome editing in humans. Technology advancements and an expanding hospital infrastructure are expected to increase the demand for genome editing in the United States.

Research and Development in China will Drive Genome Editing Demand

China is predicted to have a growing market for genome editing. The growth rate is expected to be 16.2% between 2024 and 2034. The market is expected to reach USD 4.2 billion by 2034. The government has contributed significantly to genome editing research and biotech development, fostering innovation and accelerating technology development.

China has dominated research and development in genome editing. Regulations have been implemented to regulate gene editing in humans, though concerns remain about regulating private ventures. A call for stricter regulations and international cooperation has arisen in response to ethical concerns regarding gene editing.

Innovative Technological Approaches to Boost the Market in Japan

Japan is expected to lead the market for genome editing market. A 16.5% CAGR is predicted for the market during the forecast period. By 2034, the market is expected to generate USD 2.8 billion in revenues. Biotechnology is one of Japan's most advanced fields. Several technological advances have contributed to the growth of genome editing in Japan.

Age-related diseases are among the top medical innovations in Japan, which is one of the world's most rapidly aging populations. A growing interest in genome editing in Japan is driven by its potential to develop personalized treatments for diseases caused by aging.

New gene Therapy development in South Korea to Fuel Market

Research and development in genome editing has been a major focus of South Korea, contributing significantly to the field. A market growth of USD 1.6 billion is anticipated by 2034. South Korea has conducted extensive research into genome editing. Using CRISPR-Cas9 gene scissors and other gene-editing technologies, the country has been actively involved in developing and applying gene-editing technologies.

Several biotech companies in South Korea specialize in genome editing technologies. The products or services provided by some companies include new therapies, gene editing, and agricultural applications. The biotechnology industry in South Korea is highly competitive, and it places great importance on research and development. South Korea invests heavily in cutting-edge technologies that promote growth and innovation as part of its initiatives to maintain its competitiveness globally.

Government Initiatives in the United Kingdom to Drive the Market

Many renowned universities and research institutions throughout the United Kingdom are actively involved in genome editing research. Research from these institutions is often relevant to medicine and agriculture and contributes to the advancement of the field.

The regulatory environment heavily influences genome editing market dynamics in the United Kingdom. A policy to balance ethical and safety considerations with innovation is being developed in the United Kingdom with respect to genome editing regulations. The United Kingdom is actively researching genetic disorders and clinical trials using genome editing techniques.

A CAGR of 17.1% is projected for the United Kingdom between 2024 and 2034. Government initiatives, private investors, and international collaborations have all invested in and funded the genome editing industry in the United Kingdom.

Category-wise Insights

This section illustrates the market's leading segment. Based on the technology, the meganucleases segment is expected to expand at a CAGR of 15.6% by 2034. Based on the delivery, the ex-vivo segment is expected to expand at a CAGR of 15.3% by 2034.

Category CAGR from 2024 to 2034
Meganucleases 15.6%
Ex-vivo 15.3%

Meganuclease Technology Advances the Field of Genome Editing Market

A meganuclease's ability to recognize and cut specific DNA sequences is highly precise. By 2034, the meganucleas sector is forecasted to record a CAGR of 15.6%. As a result of their specificity, they can be used for targeted genome editing with minimal off-target effects.

Genome editing and repair can be achieved with meganuclease by inducing homologous recombination. Inactivation of specific genes can be achieved using meganuclease’s that cut and target DNA sequences. For example, CCR5, an important HIV receptor, has been targeted by meganuclease in clinical trials.

Ex-vivo Segment to Hold a Dominant Share in the Market

Ex CRISPR-Cas9, zinc finger nucleases (ZFNs), or transcription activator-like effector nucleases (TALENs) are among the tools that can be introduced into cells for vivo genome editing. Infecting cells with viruses, electroporation, and lipids can all be accomplished this way, with a variety of techniques available for each.

The ex-vivo market is predicted to expand at a CAGR of 15.3% through 2034. In addition to treating genetic disorders and cancer, ex vivo genome editing is also effective against certain viral infections. Mutations in DNA may be corrected, immune response enhanced, or therapeutic genes may be introduced by altering the genetic material of cells.

Competitive Landscape

The manufacturers of genome editing tools are seeking strategic partnerships and collaborations with other companies to expand their research capabilities. Research and development activities by several market players are leading to innovations in genetic testing.

Key Market Developments

  • In January 2023, GenKOre, Inc., a Korea-based biotechnology company that specializes in hypercompact CRISPR-Cas tools, entered into a strategic collaboration to develop therapeutics that allow in-vivo gene editing. Using GenKOre's TaRGET platform, this collaboration used the company's proprietary CRISPR-Cas technology.
  • In October 2023, Integrated DNA Technologies (IDT), a world-leading provider of genomic solutions, announced that it had completed its Therapeutic Oligonucleotide Manufacturing facility in Coralville, Iowa.

Key Coverage of Genome Editing Report

  • Study on Genome Editing, Performance Analysis of Genome Editing
  • Opportunity Analysis of Genome Editing
  • Genome Editing Market Scenario
  • South Korea Genome Editing in the Market
  • Competitive Analysis of Top Genome Editing and Support Companies

Report Scope

Attributes Details
Estimated Market Size in 2024 USD 6.2 billion
Projected Market Valuation in 2034 USD 26.5 billion
Value-based CAGR 2024 to 2034 15.7%
Forecast Period 2024 to 2034
Historical Data Available for 2019 to 2023
Market Analysis Value in USD billion
Key Regions Covered North America; Latin America; Western Europe; Eastern Europe; South Asia and Pacific; East Asia; The Middle East and Africa
Key Market Segments Covered Technology, Delivery, Mode, End Use, Application, Region
Key Countries Profiled The United States, Canada, Brazil, Mexico, Germany, The United Kingdom, France, Spain, Italy, Poland, Russia, Czech Republic, Romania, India, Bangladesh, Australia, New Zealand, China, Japan, South Korea, GCC countries, South Africa, Israel
Key Companies Profiled Merck KGaA; Cibus; Recombinetics Inc.; Sangamo; Editas Medicine; Precision Biosciences; CRISPR Therapeutics; Intellia Therapeutics Inc.; Caribou Biosciences Inc.; Cellectis S.A.; AstraZeneca; Takara Bio USA
Table of Content
  • 1. Executive Summary
  • 2. Market Overview
  • 3. Market Background
  • 4. Global Market Analysis 2019 to 2023 and Forecast, 2024 to 2034
  • 5. Global Market Analysis 2019 to 2023 and Forecast 2024 to 2034, By Technology
    • 5.1. Meganucleases
    • 5.2. (CRISPR)/Cas9
    • 5.3. TALENs/MegaTALs
    • 5.4. ZFN
    • 5.5. Others
  • 6. Global Market Analysis 2019 to 2023 and Forecast 2024 to 2034, By Delivery
    • 6.1. Ex-vivo
    • 6.2. In-vivo
  • 7. Global Market Analysis 2019 to 2023 and Forecast 2024 to 2034, By Mode
    • 7.1. Contract
    • 7.2. In-house
  • 8. Global Market Analysis 2019 to 2023 and Forecast 2024 to 2034, By End-use
    • 8.1. Biotechnology & Pharmaceutical Companies
    • 8.2. Academic & Government Research Institutes
    • 8.3. Contract Research Organizations
  • 9. Global Market Analysis 2019 to 2023 and Forecast 2024 to 2034, By Application
    • 9.1. Genetic Engineering
      • 9.1.1. Cell Line Engineering
      • 9.1.2. Animal Genetic Engineering
      • 9.1.3. Plant Genetic Engineering
      • 9.1.4. Others
    • 9.2. Clinical Applications
      • 9.2.1. Diagnostics
      • 9.2.2. Therapy Development
  • 10. Global Market Analysis 2019 to 2023 and Forecast 2024 to 2034, By Region
    • 10.1. North America
    • 10.2. Latin America
    • 10.3. Western Europe
    • 10.4. Eastern Europe
    • 10.5. South Asia and Pacific
    • 10.6. East Asia
    • 10.7. Middle East and Africa
  • 11. North America Market Analysis 2019 to 2023 and Forecast 2024 to 2034, By Country
  • 12. Latin America Market Analysis 2019 to 2023 and Forecast 2024 to 2034, By Country
  • 13. Western Europe Market Analysis 2019 to 2023 and Forecast 2024 to 2034, By Country
  • 14. Eastern Europe Market Analysis 2019 to 2023 and Forecast 2024 to 2034, By Country
  • 15. South Asia and Pacific Market Analysis 2019 to 2023 and Forecast 2024 to 2034, By Country
  • 16. East Asia Market Analysis 2019 to 2023 and Forecast 2024 to 2034, By Country
  • 17. Middle East and Africa Market Analysis 2019 to 2023 and Forecast 2024 to 2034, By Country
  • 18. Key Countries Market Analysis
  • 19. Market Structure Analysis
  • 20. Competition Analysis
    • 20.1. Merck KGaA
    • 20.2. Cibus, Recombinetics, Inc.
    • 20.3. Sangamo
    • 20.4. Editas Medicine
    • 20.5. Precision Biosciences
    • 20.6. CRISPR Therapeutics
    • 20.7. Intellia Therapeutics, Inc.
    • 20.8. Caribou Biosciences, Inc.
    • 20.9. Cellectis S.A.
    • 20.10. AstraZeneca
    • 20.11. Takara Bio USA
  • 21. Assumptions & Acronyms Used
  • 22. Research Methodology

Genome Editing - Key Segments

By Technology:

  • Meganucleases
  • CRISPR/Cas9
  • TALENs/MegaTALs
  • ZFN
  • Others

By Delivery:

  • Ex-vivo
  • In-vivo

By Mode:

  • Contract
  • In-house

By End User:

  • Biotechnology & Pharmaceutical Companies
  • Academic & Government Research Institutes
  • Contract Research Organizations

By Application:

  • Genetic Engineering
    • Cell Line Engineering
    • Animal Genetic Engineering
    • Plant Genetic Engineering
    • Others
  • Clinical Applications
    • Diagnostics
    • Therapy Development

By Region:

  • North America
  • Latin America
  • Western Europe
  • Eastern Europe
  • South Asia and Pacific
  • East Asia
  • Middle East and Africa

Frequently Asked Questions

What is the estimated value of the genome editing in 2024?

As of 2024, the genome editing market is expected to be valued at USD 6.2 billion.

What is the anticipated market value for genome editing in 2034?

By 2034, the market value of genome editing is expected to reach USD 26.5 billion.

What is the projected forecast CAGR for genome editing from 2024 to 2034?

From 2024 to 2034, genome editing is expected to flourish at a CAGR of 15.7%

Based on technology, which segments dominate the genome editing market?

The meganucleases segment is expected to increase at 15.6% CAGR by 2034.

Which country is likely to dominate the genome editing?

South Korea is expected to hold the largest market, with a CAGR of 17.8%.

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