The DNA polymerase market is likely to register positive growth with the overall valuation forecast to reach US$ 353.9 million in 2023. Thee demand for DNA Polymerases is projected to surge with a projected CAGR of 6.2% to reach US$ 647.5 million.
DNA polymerase plays key roles in diagnostics applications including PCR tests, owing to superior efficacy in synthesizing new strands of DNA. DNA polymerase is key to making use of PCR technologies for biological applications. Over the past decade, significant progress has been achieved in terms of processivity, specificity, fidelity, and thermostability.
Hot start and high-fidelity DNA polymerase technologies are some of the new advances that are rapidly gaining ground in the industry. Innovations in colony screening assays, next-generation sequencing, and Sanger sequencing enable high levels of accuracy, previously inaccessible in the field.
ESOMAR-certified market analysis and consulting company Future Market Insights (FMI) delivers insights into key factors driving the DNA polymerase market in its latest report. Furthermore, an evaluation of the effect of the COVID-19 pandemic on the DNA polymerase market in general, and an analysis of sales in 20+ high-growth.
| Attributes | Details |
|---|---|
| DNA Polymerase Market Value (2022) | US$ 335.1 million |
| DNA Polymerase Market Value (2023) | US$ 353.9 million |
| DNA Polymerase Market Expected Value (2033) | US$ 647.5 million |
| DNA Polymerase Market Projected CAGR (2023 to 2033) | 6.2% |
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Efforts by governments driving investment into research and development and increased levels of healthcare spending are expected to fuel the demand for DNA polymerase applications. Regulators such as the Food and Drugs Organization (FDA) are emphasizing the use of molecular diagnostics technology leveraging the expiry of drug patents and the development of generic biologics with lower interference in bioprocessing, driving demand between 2018 and 2022.
Technological innovations and strategic collaborations by leading market players will positively influence the market. Developed countries have actively taken to DNA polymerase assays and these regional markets have exhibited steady growth.
However, emerging economies continue to lag primarily owing to the lack of awareness and reduced GDP and healthcare spending in the region. Further, the high costs of research and the use of such tests have majorly impacted the growth prospects of the market. The COVID-19 crisis has impacted research activities in addition to disrupting the supply chain and affecting market growth, albeit for a short duration of time. Future Market Insights has projected the market to progress at a promising CAGR of 6.2% through 2033.
According to a report in the U.S National Library of Medicine, protein to protein interactions is a key part of DNA polymerase applications and regulation. Structural studies conducted on DNA polymerases along with protein partners are providing major insights into how polymerase catalytic subunits are interacting with its accessory subunits, while other protein factors are proving important to the varied DNA transactions.
Given the large number and complexity of DNA transactions dependent on DNA polymerase activity, it is not surprising that cells in various organisms comprise multiple specialized DNA polymerases, most of which have been discovered only in recent years.
Growing awareness about the role of DNA polymerase in DNA replication, DSB repair, mitochondrial replication & repair, ICL repair somatic hypermutation, and more on the basis of prototype enzyme families are expected to play major roles in future developments of the industry.
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According to a report in the US National Library of Medicine, protein to protein interactions is a key part of DNA polymerase applications and regulation. Structural studies conducted on DNA polymerases along with protein partners are providing major insights into how polymerase catalytic subunits are interacting with its accessory subunits, while other protein factors are proving important to the varied DNA transactions.
Given the large number and complexity of DNA transactions dependent on DNA polymerase activity, it is not surprising that cells in various organisms comprise multiple specialized DNA polymerases, most of which have been discovered only in recent years.
Growing awareness about the role of DNA polymerase in DNA replication, DSB repair, mitochondrial replication & repair, ICL repair somatic hypermutation, and more on the basis of prototype enzyme families are expected to play major roles in future developments of the industry.
Rising Deployment of DNA polymerases in The Field of Epigenetics Research to Drive Market Growth
The rapidly increasing use of DNA polymerases in molecular diagnostics and point-of-care kits is expected to influence the adoption of DNA polymerases. Increasing applications of DNA polymerases in the field of epigenetics research, along with the increasing investments in life sciences is also expected to bolster revenue growth in the global market.
The distinct characteristics of every DNA polymerase type may account for the potential development of reagents. As a result, efforts to explore new DNA polymerase variants have been one of the major focuses of researchers in this field. Thermostable DNA polymerases are especially finding key roles in terms of PCR-related methodologies in molecular biology.
New protein engineering techniques are being used to generate artificial or mutant DNA polymerases many of which are developed to be suitable for industry specific purposes among the several kinds of DNA manipulation procedures. This will remain a key driving factor for the DNA polymerase market through the assessment period.
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High Expenses of Reagents to Boost Market Growth
With major investments into biopharmaceuticals continuing, the demand for DNA polymerase is expected to rise in the coming decade. However, players in the industry are also likely to face challenges to operations through the assessment period.
The high cost of reagents and availability of relatively affordable alternative techniques are projected to limit market growth through the forecast period. In addition, the lack of adequate capital, infrastructure, and skilled professionals in the field are also challenges to market players. Furthermore, applications in DNA polymerase are fairly new. As a result, a lack of awareness is also a restraining factor influencing the market.
United States to Dominate the Industry
As per the FMI report, the United States is likely to hold the lead in the global DNA polymerase market through the assessment period. Easy access to capital and investments in cutting-edge healthcare infrastructure generates lucrative opportunities for growth in the United States market.
The United States is also home to a large number of contract manufacturing organizations and bioprocess organizations, which will support market expansion in the long term. Also, investments towards the development of generic biologics following the expiry of patented drugs will contribute to growth in the country. United State has emerged as a leading market, accounting for over 38.6% of the total demand registered in 2022.
Development in Healthcare Facilities to Boost the United Kingdom’s Market
The United Kingdom has emerged as a lucrative market for DNA polymerase manufacturers. The expansion of healthcare infrastructure and the availability of skilled professionals are driving factors. The growth of the massive biopharmaceutical and pharmaceutical sectors in the country, and associated government initiatives support growth.
Investments and collaborations for research including the National Health Service, players from pharmaceutical companies, and academic & research institutes for experimental medicine and genetics will create a favorable environment for DNA polymerase market players.
Research Activities by Multiple MNCs to Drive the Market Growth
The DNA polymerase market in China is fairly new. However, growth in the country is expected to be strong in the near future, driven by major investments being made into healthcare infrastructure expansion.
While lack of awareness will remain a concern, the presence of numerous contract research organizations within China associated with biopharmaceuticals, coupled with the migration of drug production facilities by international manufacturers is likely to contribute to positive prospects of growth for the market in China through 2033. The market in China is projected to rise at a CAGR of 9.4% over the upcoming decades.
Contracts and Acquisitions among key Players to Raise the Market Growth
As per a World Bank report, the spending on Japan in Healthcare accounted for nearly 11% of its GDP in 2019. A rising focus in the country on advanced healthcare technologies and the growth in contract development and manufacturing will find traction.
Globalization of the contract manufacturing sector in Japan in addition to strategic acquisitions and collaborations in terms of biologics products will pave the way for faster expansion of the DNA polymerase market within the country. The market in Japan accounted for over 4.6% of the total demand registered in 2022.
High Investments into Genome Research to Boost Growth
DNA polymerase can be broadly classified into prokaryotic and eukaryotic variants. Prokaryotic DNA polymerase is projected to hold a larger market share through the forecast period, owing to applications in diagnostic processes, including PCR tests.
Eukaryotic DNA polymerase is expected to display fast growth as well owing to recent, major investments into genome research and potential applications outside of conventional uses in the healthcare sector. Also, the introduction of high-fidelity DNA polymerase will prove beneficial to growth.
PCR based Technology to Propel the Segment Demand
DNA polymerase finds roles with a number of end users including hospitals, molecular diagnostics companies, biopharmaceutical companies, diagnostic laboratories, and academic & research institutes. Of these, molecular diagnostics companies will account for a relatively larger market share.
The growing use of PCR based technologies and investments in distribution agreements, especially since the onset of the pandemic are key factors driving demand. Further, academic and research institutes account for faster growth, owing to potential applications apart from healthcare, creating lucrative opportunities.
The global DNA polymerase market is largely consolidated, with leading biopharmaceutical companies holding on to a major market share. Major players in the industry are focusing increasingly on product research and launch, exploring new applications in line with national and international regulatory standards.
| Attribute | Details |
|---|---|
| Forecast Period | 2023 to2033 |
| Historical Data Available for | 2018 to 2022 |
| DNA Polymerase Market Value (2023) | US$ 353.9 million |
| DNA Polymerase Market Expected Value (2033) | US$ 647.5 million |
| Market Analysis | US$ million for Value |
| Key Regions Covered |
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| Key Countries Covered |
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| Key Segments Covered |
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| Key Companies Profiled |
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| Customization & Pricing | Available upon Request |
The market is valued at US$ 353.9 million in 2023.
The growth potential of the DNA polymerase market is 6.2% through 2033.
The global market size is expected to reach US$ 647.5 million by 2033.
China holds high lucrativeness, demonstrating a CAGR of 9.4% through 2033.
Prokaryotic DNA polymerase is likely to remain preferred through 2033.
1. Executive Summary 1.1. Global Market Outlook 1.2. Demand-side Trends 1.3. Supply-side Trends 1.4. Technology Roadmap Analysis 1.5. Analysis and Recommendations 2. Market Overview 2.1. Market Coverage / Taxonomy 2.2. Market Definition / Scope / Limitations 3. Market Background 3.1. Market Dynamics 3.1.1. Drivers 3.1.2. Restraints 3.1.3. Opportunity 3.1.4. Trends 3.2. Scenario Forecast 3.2.1. Demand in Optimistic Scenario 3.2.2. Demand in Likely Scenario 3.2.3. Demand in Conservative Scenario 3.3. Opportunity Map Analysis 3.4. Product Life Cycle Analysis 3.5. Supply Chain Analysis 3.5.1. Supply Side Participants and their Roles 3.5.1.1. Producers 3.5.1.2. Mid-Level Participants (Traders/ Agents/ Brokers) 3.5.1.3. Wholesalers and Distributors 3.5.2. Value Added and Value Created at Node in the Supply Chain 3.5.3. List of Raw Material Suppliers 3.5.4. List of Existing and Potential Buyer’s 3.6. Investment Feasibility Matrix 3.7. Value Chain Analysis 3.7.1. Profit Margin Analysis 3.7.2. Wholesalers and Distributors 3.7.3. Retailers 3.8. PESTLE and Porter’s Analysis 3.9. Regulatory Landscape 3.9.1. By Key Regions 3.9.2. By Key Countries 3.10. Regional Parent Market Outlook 3.11. Production and Consumption Statistics 3.12. Import and Export Statistics 4. Global Market Analysis 2018 to 2022 and Forecast, 2023 to 2033 4.1. Historical Market Size Value (US$ Million) & Volume (Litre) Analysis, 2018 to 2022 4.2. Current and Future Market Size Value (US$ Million) & Volume (Litre) Projections, 2023 to 2033 4.2.1. Y-o-Y Growth Trend Analysis 4.2.2. Absolute $ Opportunity Analysis 5. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Product Type 5.1. Introduction / Key Findings 5.2. Historical Market Size Value (US$ Million) & Volume (Litre) Analysis By Product Type, 2018 to 2022 5.3. Current and Future Market Size Value (US$ Million) & Volume (Litre) Analysis and Forecast By Product Type, 2023 to 2033 5.3.1. Prokaryotic DNA polymerase 5.3.2. Eukaryotic DNA polymerase 5.4. Y-o-Y Growth Trend Analysis By Product Type, 2018 to 2022 5.5. Absolute $ Opportunity Analysis By Product Type, 2023 to 2033 6. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By End Use 6.1. Introduction / Key Findings 6.2. Historical Market Size Value (US$ Million) & Volume (Litre) Analysis By End Use, 2018 to 2022 6.3. Current and Future Market Size Value (US$ Million) & Volume (Litre) Analysis and Forecast By End Use, 2023 to 2033 6.3.1. Molecular diagnostics companies 6.3.2. Diagnostic laboratories 6.3.3. Academic and research institutes 6.3.4. Biopharmaceutical companies 6.3.5. Hospitals 6.4. Y-o-Y Growth Trend Analysis By End Use, 2018 to 2022 6.5. Absolute $ Opportunity Analysis By End Use, 2023 to 2033 7. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Region 7.1. Introduction 7.2. Historical Market Size Value (US$ Million) & Volume (Litre) Analysis By Region, 2018 to 2022 7.3. Current Market Size Value (US$ Million) & Volume (Litre) Analysis and Forecast By Region, 2023 to 2033 7.3.1. North America 7.3.2. Latin America 7.3.3. Europe 7.3.4. Asia Pacific 7.3.5. MEA 7.4. Market Attractiveness Analysis By Region 8. North America Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country 8.1. Historical Market Size Value (US$ Million) & Volume (Litre) Trend Analysis By Market Taxonomy, 2018 to 2022 8.2. Market Size Value (US$ Million) & Volume (Litre) Forecast By Market Taxonomy, 2023 to 2033 8.2.1. By Country 8.2.1.1. U.S. 8.2.1.2. Canada 8.2.2. By Product Type 8.2.3. By End Use 8.3. Market Attractiveness Analysis 8.3.1. By Country 8.3.2. By Product Type 8.3.3. By End Use 8.4. Key Takeaways 9. Latin America Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country 9.1. Historical Market Size Value (US$ Million) & Volume (Litre) Trend Analysis By Market Taxonomy, 2018 to 2022 9.2. Market Size Value (US$ Million) & Volume (Litre) Forecast By Market Taxonomy, 2023 to 2033 9.2.1. By Country 9.2.1.1. Brazil 9.2.1.2. Mexico 9.2.1.3. Rest of Latin America 9.2.2. By Product Type 9.2.3. By End Use 9.3. Market Attractiveness Analysis 9.3.1. By Country 9.3.2. By Product Type 9.3.3. By End Use 9.4. Key Takeaways 10. Europe Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country 10.1. Historical Market Size Value (US$ Million) & Volume (Litre) Trend Analysis By Market Taxonomy, 2018 to 2022 10.2. Market Size Value (US$ Million) & Volume (Litre) Forecast By Market Taxonomy, 2023 to 2033 10.2.1. By Country 10.2.1.1. Germany 10.2.1.2. U.K. 10.2.1.3. France 10.2.1.4. Spain 10.2.1.5. Italy 10.2.1.6. Rest of Europe 10.2.2. By Product Type 10.2.3. By End Use 10.3. Market Attractiveness Analysis 10.3.1. By Country 10.3.2. By Product Type 10.3.3. By End Use 10.4. Key Takeaways 11. Asia Pacific Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country 11.1. Historical Market Size Value (US$ Million) & Volume (Litre) Trend Analysis By Market Taxonomy, 2018 to 2022 11.2. Market Size Value (US$ Million) & Volume (Litre) Forecast By Market Taxonomy, 2023 to 2033 11.2.1. By Country 11.2.1.1. China 11.2.1.2. Japan 11.2.1.3. South Korea 11.2.1.4. Singapore 11.2.1.5. Thailand 11.2.1.6. Indonesia 11.2.1.7. Australia 11.2.1.8. New Zealand 11.2.1.9. Rest of Asia Pacific 11.2.2. By Product Type 11.2.3. By End Use 11.3. Market Attractiveness Analysis 11.3.1. By Country 11.3.2. By Product Type 11.3.3. By End Use 11.4. Key Takeaways 12. MEA Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country 12.1. Historical Market Size Value (US$ Million) & Volume (Litre) Trend Analysis By Market Taxonomy, 2018 to 2022 12.2. Market Size Value (US$ Million) & Volume (Litre) Forecast By Market Taxonomy, 2023 to 2033 12.2.1. By Country 12.2.1.1. GCC Countries 12.2.1.2. South Africa 12.2.1.3. Israel 12.2.1.4. Rest of MEA 12.2.2. By Product Type 12.2.3. By End Use 12.3. Market Attractiveness Analysis 12.3.1. By Country 12.3.2. By Product Type 12.3.3. By End Use 12.4. Key Takeaways 13. Key Countries Market Analysis 13.1. U.S. 13.1.1. Pricing Analysis 13.1.2. Market Share Analysis, 2022 13.1.2.1. By Product Type 13.1.2.2. By End Use 13.2. Canada 13.2.1. Pricing Analysis 13.2.2. Market Share Analysis, 2022 13.2.2.1. By Product Type 13.2.2.2. By End Use 13.3. Brazil 13.3.1. Pricing Analysis 13.3.2. Market Share Analysis, 2022 13.3.2.1. By Product Type 13.3.2.2. By End Use 13.4. Mexico 13.4.1. Pricing Analysis 13.4.2. Market Share Analysis, 2022 13.4.2.1. By Product Type 13.4.2.2. By End Use 13.5. Germany 13.5.1. Pricing Analysis 13.5.2. Market Share Analysis, 2022 13.5.2.1. By Product Type 13.5.2.2. By End Use 13.6. U.K. 13.6.1. Pricing Analysis 13.6.2. Market Share Analysis, 2022 13.6.2.1. By Product Type 13.6.2.2. By End Use 13.7. France 13.7.1. Pricing Analysis 13.7.2. Market Share Analysis, 2022 13.7.2.1. By Product Type 13.7.2.2. By End Use 13.8. Spain 13.8.1. Pricing Analysis 13.8.2. Market Share Analysis, 2022 13.8.2.1. By Product Type 13.8.2.2. By End Use 13.9. Italy 13.9.1. Pricing Analysis 13.9.2. Market Share Analysis, 2022 13.9.2.1. By Product Type 13.9.2.2. By End Use 13.10. China 13.10.1. Pricing Analysis 13.10.2. Market Share Analysis, 2022 13.10.2.1. By Product Type 13.10.2.2. By End Use 13.11. Japan 13.11.1. Pricing Analysis 13.11.2. Market Share Analysis, 2022 13.11.2.1. By Product Type 13.11.2.2. By End Use 13.12. South Korea 13.12.1. Pricing Analysis 13.12.2. Market Share Analysis, 2022 13.12.2.1. By Product Type 13.12.2.2. By End Use 13.13. Singapore 13.13.1. Pricing Analysis 13.13.2. Market Share Analysis, 2022 13.13.2.1. By Product Type 13.13.2.2. By End Use 13.14. Thailand 13.14.1. Pricing Analysis 13.14.2. Market Share Analysis, 2022 13.14.2.1. By Product Type 13.14.2.2. By End Use 13.15. Indonesia 13.15.1. Pricing Analysis 13.15.2. Market Share Analysis, 2022 13.15.2.1. By Product Type 13.15.2.2. By End Use 13.16. Australia 13.16.1. Pricing Analysis 13.16.2. Market Share Analysis, 2022 13.16.2.1. By Product Type 13.16.2.2. By End Use 13.17. New Zealand 13.17.1. Pricing Analysis 13.17.2. Market Share Analysis, 2022 13.17.2.1. By Product Type 13.17.2.2. By End Use 13.18. GCC Countries 13.18.1. Pricing Analysis 13.18.2. Market Share Analysis, 2022 13.18.2.1. By Product Type 13.18.2.2. By End Use 13.19. South Africa 13.19.1. Pricing Analysis 13.19.2. Market Share Analysis, 2022 13.19.2.1. By Product Type 13.19.2.2. By End Use 13.20. Israel 13.20.1. Pricing Analysis 13.20.2. Market Share Analysis, 2022 13.20.2.1. By Product Type 13.20.2.2. By End Use 14. Market Structure Analysis 14.1. Competition Dashboard 14.2. Competition Benchmarking 14.3. Market Share Analysis of Top Players 14.3.1. By Regional 14.3.2. By Product Type 14.3.3. By End Use 15. Competition Analysis 15.1. Competition Deep Dive 15.1.1. Thermo Fisher Scientific Inc. 15.1.1.1. Overview 15.1.1.2. Product Portfolio 15.1.1.3. Profitability by Market Segments 15.1.1.4. Sales Footprint 15.1.1.5. Strategy Overview 15.1.1.5.1. Marketing Strategy 15.1.1.5.2. Product Strategy 15.1.1.5.3. Channel Strategy 15.1.2. Hoffmann-La Roche AG 15.1.2.1. Overview 15.1.2.2. Product Portfolio 15.1.2.3. Profitability by Market Segments 15.1.2.4. Sales Footprint 15.1.2.5. Strategy Overview 15.1.2.5.1. Marketing Strategy 15.1.2.5.2. Product Strategy 15.1.2.5.3. Channel Strategy 15.1.3. Merck KGaA 15.1.3.1. Overview 15.1.3.2. Product Portfolio 15.1.3.3. Profitability by Market Segments 15.1.3.4. Sales Footprint 15.1.3.5. Strategy Overview 15.1.3.5.1. Marketing Strategy 15.1.3.5.2. Product Strategy 15.1.3.5.3. Channel Strategy 15.1.4. Qiagen N.V. 15.1.4.1. Overview 15.1.4.2. Product Portfolio 15.1.4.3. Profitability by Market Segments 15.1.4.4. Sales Footprint 15.1.4.5. Strategy Overview 15.1.4.5.1. Marketing Strategy 15.1.4.5.2. Product Strategy 15.1.4.5.3. Channel Strategy 15.1.5. Agilent Technologies Inc. 15.1.5.1. Overview 15.1.5.2. Product Portfolio 15.1.5.3. Profitability by Market Segments 15.1.5.4. Sales Footprint 15.1.5.5. Strategy Overview 15.1.5.5.1. Marketing Strategy 15.1.5.5.2. Product Strategy 15.1.5.5.3. Channel Strategy 15.1.6. Takara Bio Inc. 15.1.6.1. Overview 15.1.6.2. Product Portfolio 15.1.6.3. Profitability by Market Segments 15.1.6.4. Sales Footprint 15.1.6.5. Strategy Overview 15.1.6.5.1. Marketing Strategy 15.1.6.5.2. Product Strategy 15.1.6.5.3. Channel Strategy 15.1.7. Genescript, Illumina Inc. 15.1.7.1. Overview 15.1.7.2. Product Portfolio 15.1.7.3. Profitability by Market Segments 15.1.7.4. Sales Footprint 15.1.7.5. Strategy Overview 15.1.7.5.1. Marketing Strategy 15.1.7.5.2. Product Strategy 15.1.7.5.3. Channel Strategy 15.1.8. New England Biolabs, Inc. 15.1.8.1. Overview 15.1.8.2. Product Portfolio 15.1.8.3. Profitability by Market Segments 15.1.8.4. Sales Footprint 15.1.8.5. Strategy Overview 15.1.8.5.1. Marketing Strategy 15.1.8.5.2. Product Strategy 15.1.8.5.3. Channel Strategy 15.1.9. Bioline 15.1.9.1. Overview 15.1.9.2. Product Portfolio 15.1.9.3. Profitability by Market Segments 15.1.9.4. Sales Footprint 15.1.9.5. Strategy Overview 15.1.9.5.1. Marketing Strategy 15.1.9.5.2. Product Strategy 15.1.9.5.3. Channel Strategy 15.1.10. Promega Corporation 15.1.10.1. Overview 15.1.10.2. Product Portfolio 15.1.10.3. Profitability by Market Segments 15.1.10.4. Sales Footprint 15.1.10.5. Strategy Overview 15.1.10.5.1. Marketing Strategy 15.1.10.5.2. Product Strategy 15.1.10.5.3. Channel Strategy 16. Assumptions & Acronyms Used 17. Research Methodology
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July 2022
REP-GB-8396
250 pages
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DNA Polymerase Market
