The global Congenital Adrenal Hyperplasia treatment market garnered a market value of US$ 378.69 Million in 2022 and is expected to accumulate a market value of US$ 892 Million by registering a CAGR of 8.1% in the forecast period 2023 to 2033. Growth of the Congenital Adrenal Hyperplasia treatment market can be attributed to greater recognition of the disorder, enhancements in diagnostic and screening techniques, and progress in medical research and development. The market for Congenital Adrenal Hyperplasia treatment registered a CAGR of 5.3% in the historical period 2018 to 2022
Congenital Adrenal Hyperplasia (CAH) is a genetic disorder that affects the adrenal glands, which produce hormones that regulate various bodily functions. In CAH, there is a deficiency in one of the enzymes needed to produce these hormones, which leads to an overproduction of androgens (male sex hormones). The treatment of CAH depends on the severity of the condition and the age at which it is diagnosed. The primary goal of treatment is to replace the deficient hormones and reduce the production of androgens to normal levels.
Report Attribute | Details |
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Expected Market Value (2023) | US$ 409.36 Million |
Anticipated Forecast Value (2033) | US$ 892 Million |
Projected Growth Rate (2023-2033) | 8.1% CAGR |
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According to market research and competitive intelligence provider Future Market Insights- the market for Congenital Adrenal Hyperplasia treatment reflected a value of 5.3% during the historical period, 2018 to 2022.
In recent years, there has been a growing focus on personalized medicine and precision therapies, which could potentially drive innovation and development in the CAH treatment market. There are also ongoing efforts to improve diagnosis and screening for CAH, which could lead to earlier detection and treatment.
Thus, the market for Congenital Adrenal Hyperplasia treatment is expected to register a CAGR of 8.1% in the forecast period 2023 to 2033.
Advancements in medical research along with Increasing adoption of personalized medicine boosting market growth for CAH treatment market
Although CAH is a rare genetic disorder, the number of patients diagnosed with the condition is increasing, which is driving demand for effective treatment options. There has been significant progress in understanding the underlying mechanisms of CAH, which has led to the development of new treatment options and more effective management strategies.
Personalized medicine involves tailoring treatment to an individual patient's specific needs and genetic makeup. This approach is gaining popularity in the healthcare industry, and it has the potential to improve the efficacy of CAH treatment. There is a growing awareness of CAH among patients, healthcare providers, and the general public. This increased awareness is leading to earlier diagnosis and treatment, which can improve patient outcomes.
Many governments around the world are increasing their support for research and development in the field of rare diseases, including CAH. This support can help to drive innovation and improve access to effective treatments.
Availability of treatments bolstering the treatment for CAH treatment market
Glucocorticoids such as hydrocortisone, prednisolone, and dexamethasone are the most commonly used hormone replacement therapies for CAH. These medications replace the deficient cortisol hormone and help to reduce the production of androgens. The dosage may need to be adjusted based on the patient's individual needs and hormone levels.
In some cases, CAH may also cause a deficiency of aldosterone hormone. In such cases, mineralocorticoid replacement therapy may be recommended to maintain electrolyte balance and blood pressure.
In rare cases, surgical intervention may be required to remove adrenal tumors or affected adrenal glands. Individuals with CAH may experience infertility due to the condition's impact on reproductive hormone levels. In such cases, fertility treatments such as in vitro fertilization (IVF) may be recommended to help individuals achieve pregnancy.
Individuals with CAH may also require psychosocial support, such as counseling or support groups, to manage the emotional and psychological impact of the condition.
Cost of treatment along with Side effects of treatment affecting market growth for CAH treatment
CAH is a rare condition, and it can be challenging to diagnose and screen for the condition. This can lead to delays in treatment and a higher risk of complications. Hormone replacement therapy can be expensive, and the cost can be a significant barrier to access for some patients. This is particularly true in countries without universal healthcare coverage.
Hormone replacement therapy can have side effects, including weight gain, mood changes, and bone density loss. These side effects can impact patients' quality of life and adherence to the treatment plan. Treatment for CAH is typically lifelong, and patients may struggle to comply with the treatment regimen over time. This can lead to ineffective treatment and a higher risk of complications.
Although hormone replacement therapy is effective in managing CAH, there are currently no curative treatments available. Research and development of new treatment options are ongoing, but the availability of effective therapies remains limited.
Presence of tests and treatments leading to advanced treatment option for CAH in North America
In North America, the market for CAH treatment is primarily driven by the availability of diagnostic tools and the demand for effective therapies. Currently, the most commonly used medications for the treatment of CAH in North America include corticosteroids such as hydrocortisone, prednisone, and dexamethasone. These drugs are used to replace the deficient cortisol production in patients with CAH and to suppress the overproduction of androgens.
Other treatments that may be used for CAH include GnRH analogs, which can be used to delay the onset of puberty in affected children, and surgical interventions such as clitoral reduction surgery or vaginoplasty in female infants with ambiguous genitalia.
The North American market for CAH treatment is expected to grow in the coming years due to increasing awareness of the condition and the development of new treatment options. Thus, North America is expected to possess 45% market share for CAH treatment market in 2023.
Development of new treatment options driving growth of CAH treatment in Europe
In Europe, the Congenital Adrenal Hyperplasia (CAH) treatment market is driven by the availability of diagnostic tools and the demand for effective therapies. The market is expected to grow in the coming years due to increasing awareness of the condition, advancements in technology, and the development of new treatment options.
The most commonly used medications for the treatment of CAH in Europe are corticosteroids, which are used to replace the deficient cortisol production and to suppress the overproduction of androgens. However, other treatments such as GnRH analogs and surgical interventions may also be used in some cases.
In addition to medication, patient education and support are also important components of CAH treatment in Europe. Support groups and educational programs can help patients and their families better understand the condition and manage its symptoms. Thus, Europe is expected to hold 40% market share for CAH treatment market in 2023.
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Effective nature of Glucocorticoids increasing its use for CAH treatment
Glucocorticoids are the best medication for Congenital Adrenal Hyperplasia (CAH) because they can replace the deficient cortisol production and suppress the overproduction of androgens in patients with this condition.
In CAH, the adrenal glands are unable to produce sufficient amounts of cortisol, which can lead to a range of symptoms, including fatigue, weakness, and low blood sugar levels. Glucocorticoids such as hydrocortisone, prednisone, and dexamethasone can be used to replace the deficient cortisol production and help manage these symptoms.
In addition, glucocorticoids can also help to suppress the overproduction of androgens in patients with CAH. This is important because the excess androgens can lead to a range of physical symptoms, including early onset of puberty, short stature, and infertility.
While other medications such as GnRH analogs and surgical interventions may also be used in the treatment of CAH, glucocorticoids are generally considered the first-line therapy for this condition. They are effective, relatively safe, and can be easily administered in pill form. Thus, glucocorticoids for medication are expected to possess 43% market share for CAH treatment market in 2023.
Key players in the Congenital Adrenal Hyperplasia treatment are Neurocrine Biosciences, Diurnal Limited, Spruce Biosciences, Adrenas Therapeutics, Millendo Therapeutics, Emerge Health, Thermo Fisher Scientific, Adrenas Therapeutics, Inc., Alder Biopharmaceuticals, Inc and Zydus Lifesciences Ltd.
Report Attribute | Details |
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Market Value in 2023 | US$ 409.36 Million |
Market Value in 2033 | US$ 892 Million |
Growth Rate | CAGR of 8.1% from 2023 to 2033 |
Base Year for Estimation | 2022 |
Historical Data | 2018 to 2022 |
Forecast Period | 2023 to 2033 |
Quantitative Units | Revenue in USD Million and CAGR from 2023 to 2033 |
Report Coverage | Revenue Forecast, Volume Forecast, Company Ranking, Competitive Landscape, Growth Factors, Trends and Pricing Analysis |
Segments Covered |
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Regions Covered |
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Key Countries Profiled |
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Key Companies Profiled |
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Customization | Available Upon Request |
The market is estimated to secure a valuation of US$ 409.3 million in 2023.
The market is estimated to reach US$ 892 million by 2033.
Glucocorticoids holds high revenue potential.
North America dominates the global market.
The market is forecast to register a CAGR of 8.1% through 2033.
1. Executive Summary | Congenital Adrenal Hyperplasia Treatment Market
1.1. Global Market Outlook
1.2. Demand-side Trends
1.3. Supply-side Trends
1.4. Technology Roadmap Analysis
1.5. Analysis and Recommendations
2. Market Overview
2.1. Market Coverage / Taxonomy
2.2. Market Definition / Scope / Limitations
3. Market Background
3.1. Market Dynamics
3.1.1. Drivers
3.1.2. Restraints
3.1.3. Opportunity
3.1.4. Trends
3.2. Scenario Forecast
3.2.1. Demand in Optimistic Scenario
3.2.2. Demand in Likely Scenario
3.2.3. Demand in Conservative Scenario
3.3. Opportunity Map Analysis
3.4. Investment Feasibility Matrix
3.5. PESTLE and Porter’s Analysis
3.6. Regulatory Landscape
3.6.1. By Key Regions
3.6.2. By Key Countries
3.7. Regional Parent Market Outlook
4. Global Market Analysis 2018 to 2022 and Forecast, 2023 to 2033
4.1. Historical Market Size Value (US$ Million) Analysis, 2018 to 2022
4.2. Current and Future Market Size Value (US$ Million) Projections, 2023 to 2033
4.2.1. Y-o-Y Growth Trend Analysis
4.2.2. Absolute $ Opportunity Analysis
5. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Type
5.1. Introduction / Key Findings
5.2. Historical Market Size Value (US$ Million) Analysis By Type, 2018 to 2022
5.3. Current and Future Market Size Value (US$ Million) Analysis and Forecast By Type, 2023 to 2033
5.3.1. Classic Congenital Adrenal Hyperplasia
5.3.2. Non-classic Congenital Adrenal Hyperplasia
5.4. Y-o-Y Growth Trend Analysis By Type, 2018 to 2022
5.5. Absolute $ Opportunity Analysis By Type, 2023 to 2033
6. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Treatment
6.1. Introduction / Key Findings
6.2. Historical Market Size Value (US$ Million) Analysis By Treatment, 2018 to 2022
6.3. Current and Future Market Size Value (US$ Million) Analysis and Forecast By Treatment, 2023 to 2033
6.3.1. Medication
6.3.1.1. Hormone Replacement Therapy
6.3.1.2. Corticosteroid
6.3.1.3. Glucocorticoids
6.3.1.4. Salt Supplements
6.3.1.5. Others
6.3.2. Surgery
6.4. Y-o-Y Growth Trend Analysis By Treatment, 2018 to 2022
6.5. Absolute $ Opportunity Analysis By Treatment, 2023 to 2033
7. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By End-user
7.1. Introduction / Key Findings
7.2. Historical Market Size Value (US$ Million) Analysis By End-user , 2018 to 2022
7.3. Current and Future Market Size Value (US$ Million) Analysis and Forecast By End-user , 2023 to 2033
7.3.1. Hospitals
7.3.2. Pharmacies
7.3.3. Specialty Clinics
7.4. Y-o-Y Growth Trend Analysis By End-user , 2018 to 2022
7.5. Absolute $ Opportunity Analysis By End-user , 2023 to 2033
8. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Region
8.1. Introduction
8.2. Historical Market Size Value (US$ Million) Analysis By Region, 2018 to 2022
8.3. Current Market Size Value (US$ Million) Analysis and Forecast By Region, 2023 to 2033
8.3.1. North America
8.3.2. Latin America
8.3.3. Europe
8.3.4. South Asia
8.3.5. East Asia
8.3.6. Oceania
8.3.7. MEA
8.4. Market Attractiveness Analysis By Region
9. North America Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
9.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022
9.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033
9.2.1. By Country
9.2.1.1. U.S.
9.2.1.2. Canada
9.2.2. By Type
9.2.3. By Treatment
9.2.4. By End-user
9.3. Market Attractiveness Analysis
9.3.1. By Country
9.3.2. By Type
9.3.3. By Treatment
9.3.4. By End-user
9.4. Key Takeaways
10. Latin America Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
10.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022
10.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033
10.2.1. By Country
10.2.1.1. Brazil
10.2.1.2. Mexico
10.2.1.3. Rest of Latin America
10.2.2. By Type
10.2.3. By Treatment
10.2.4. By End-user
10.3. Market Attractiveness Analysis
10.3.1. By Country
10.3.2. By Type
10.3.3. By Treatment
10.3.4. By End-user
10.4. Key Takeaways
11. Europe Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
11.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022
11.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033
11.2.1. By Country
11.2.1.1. Germany
11.2.1.2. United Kingdom
11.2.1.3. France
11.2.1.4. Spain
11.2.1.5. Italy
11.2.1.6. Rest of Europe
11.2.2. By Type
11.2.3. By Treatment
11.2.4. By End-user
11.3. Market Attractiveness Analysis
11.3.1. By Country
11.3.2. By Type
11.3.3. By Treatment
11.3.4. By End-user
11.4. Key Takeaways
12. South Asia Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
12.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022
12.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033
12.2.1. By Country
12.2.1.1. India
12.2.1.2. Malaysia
12.2.1.3. Singapore
12.2.1.4. Thailand
12.2.1.5. Rest of South Asia
12.2.2. By Type
12.2.3. By Treatment
12.2.4. By End-user
12.3. Market Attractiveness Analysis
12.3.1. By Country
12.3.2. By Type
12.3.3. By Treatment
12.3.4. By End-user
12.4. Key Takeaways
13. East Asia Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
13.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022
13.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033
13.2.1. By Country
13.2.1.1. China
13.2.1.2. Japan
13.2.1.3. South Korea
13.2.2. By Type
13.2.3. By Treatment
13.2.4. By End-user
13.3. Market Attractiveness Analysis
13.3.1. By Country
13.3.2. By Type
13.3.3. By Treatment
13.3.4. By End-user
13.4. Key Takeaways
14. Oceania Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
14.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022
14.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033
14.2.1. By Country
14.2.1.1. Australia
14.2.1.2. New Zealand
14.2.2. By Type
14.2.3. By Treatment
14.2.4. By End-user
14.3. Market Attractiveness Analysis
14.3.1. By Country
14.3.2. By Type
14.3.3. By Treatment
14.3.4. By End-user
14.4. Key Takeaways
15. MEA Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
15.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022
15.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033
15.2.1. By Country
15.2.1.1. GCC Countries
15.2.1.2. South Africa
15.2.1.3. Israel
15.2.1.4. Rest of MEA
15.2.2. By Type
15.2.3. By Treatment
15.2.4. By End-user
15.3. Market Attractiveness Analysis
15.3.1. By Country
15.3.2. By Type
15.3.3. By Treatment
15.3.4. By End-user
15.4. Key Takeaways
16. Key Countries Market Analysis
16.1. USA
16.1.1. Pricing Analysis
16.1.2. Market Share Analysis, 2022
16.1.2.1. By Type
16.1.2.2. By Treatment
16.1.2.3. By End-user
16.2. Canada
16.2.1. Pricing Analysis
16.2.2. Market Share Analysis, 2022
16.2.2.1. By Type
16.2.2.2. By Treatment
16.2.2.3. By End-user
16.3. Brazil
16.3.1. Pricing Analysis
16.3.2. Market Share Analysis, 2022
16.3.2.1. By Type
16.3.2.2. By Treatment
16.3.2.3. By End-user
16.4. Mexico
16.4.1. Pricing Analysis
16.4.2. Market Share Analysis, 2022
16.4.2.1. By Type
16.4.2.2. By Treatment
16.4.2.3. By End-user
16.5. Germany
16.5.1. Pricing Analysis
16.5.2. Market Share Analysis, 2022
16.5.2.1. By Type
16.5.2.2. By Treatment
16.5.2.3. By End-user
16.6. United Kingdom
16.6.1. Pricing Analysis
16.6.2. Market Share Analysis, 2022
16.6.2.1. By Type
16.6.2.2. By Treatment
16.6.2.3. By End-user
16.7. France
16.7.1. Pricing Analysis
16.7.2. Market Share Analysis, 2022
16.7.2.1. By Type
16.7.2.2. By Treatment
16.7.2.3. By End-user
16.8. Spain
16.8.1. Pricing Analysis
16.8.2. Market Share Analysis, 2022
16.8.2.1. By Type
16.8.2.2. By Treatment
16.8.2.3. By End-user
16.9. Italy
16.9.1. Pricing Analysis
16.9.2. Market Share Analysis, 2022
16.9.2.1. By Type
16.9.2.2. By Treatment
16.9.2.3. By End-user
16.10. India
16.10.1. Pricing Analysis
16.10.2. Market Share Analysis, 2022
16.10.2.1. By Type
16.10.2.2. By Treatment
16.10.2.3. By End-user
16.11. Malaysia
16.11.1. Pricing Analysis
16.11.2. Market Share Analysis, 2022
16.11.2.1. By Type
16.11.2.2. By Treatment
16.11.2.3. By End-user
16.12. Singapore
16.12.1. Pricing Analysis
16.12.2. Market Share Analysis, 2022
16.12.2.1. By Type
16.12.2.2. By Treatment
16.12.2.3. By End-user
16.13. Thailand
16.13.1. Pricing Analysis
16.13.2. Market Share Analysis, 2022
16.13.2.1. By Type
16.13.2.2. By Treatment
16.13.2.3. By End-user
16.14. China
16.14.1. Pricing Analysis
16.14.2. Market Share Analysis, 2022
16.14.2.1. By Type
16.14.2.2. By Treatment
16.14.2.3. By End-user
16.15. Japan
16.15.1. Pricing Analysis
16.15.2. Market Share Analysis, 2022
16.15.2.1. By Type
16.15.2.2. By Treatment
16.15.2.3. By End-user
16.16. South Korea
16.16.1. Pricing Analysis
16.16.2. Market Share Analysis, 2022
16.16.2.1. By Type
16.16.2.2. By Treatment
16.16.2.3. By End-user
16.17. Australia
16.17.1. Pricing Analysis
16.17.2. Market Share Analysis, 2022
16.17.2.1. By Type
16.17.2.2. By Treatment
16.17.2.3. By End-user
16.18. New Zealand
16.18.1. Pricing Analysis
16.18.2. Market Share Analysis, 2022
16.18.2.1. By Type
16.18.2.2. By Treatment
16.18.2.3. By End-user
16.19. GCC Countries
16.19.1. Pricing Analysis
16.19.2. Market Share Analysis, 2022
16.19.2.1. By Type
16.19.2.2. By Treatment
16.19.2.3. By End-user
16.20. South Africa
16.20.1. Pricing Analysis
16.20.2. Market Share Analysis, 2022
16.20.2.1. By Type
16.20.2.2. By Treatment
16.20.2.3. By End-user
16.21. Israel
16.21.1. Pricing Analysis
16.21.2. Market Share Analysis, 2022
16.21.2.1. By Type
16.21.2.2. By Treatment
16.21.2.3. By End-user
17. Market Structure Analysis
17.1. Competition Dashboard
17.2. Competition Benchmarking
17.3. Market Share Analysis of Top Players
17.3.1. By Regional
17.3.2. By Type
17.3.3. By Treatment
17.3.4. By End-user
18. Competition Analysis
18.1. Competition Deep Dive
18.1.1. Neurocrine Biosciences
18.1.1.1. Overview
18.1.1.2. Product Portfolio
18.1.1.3. Profitability by Market Segments
18.1.1.4. Sales Footprint
18.1.1.5. Strategy Overview
18.1.1.5.1. Marketing Strategy
18.1.2. Diurnal Limited
18.1.2.1. Overview
18.1.2.2. Product Portfolio
18.1.2.3. Profitability by Market Segments
18.1.2.4. Sales Footprint
18.1.2.5. Strategy Overview
18.1.2.5.1. Marketing Strategy
18.1.3. Spruce Biosciences
18.1.3.1. Overview
18.1.3.2. Product Portfolio
18.1.3.3. Profitability by Market Segments
18.1.3.4. Sales Footprint
18.1.3.5. Strategy Overview
18.1.3.5.1. Marketing Strategy
18.1.4. Adrenas Therapeutics
18.1.4.1. Overview
18.1.4.2. Product Portfolio
18.1.4.3. Profitability by Market Segments
18.1.4.4. Sales Footprint
18.1.4.5. Strategy Overview
18.1.4.5.1. Marketing Strategy
18.1.5. Millendo Therapeutics
18.1.5.1. Overview
18.1.5.2. Product Portfolio
18.1.5.3. Profitability by Market Segments
18.1.5.4. Sales Footprint
18.1.5.5. Strategy Overview
18.1.5.5.1. Marketing Strategy
18.1.6. Emerge Health
18.1.6.1. Overview
18.1.6.2. Product Portfolio
18.1.6.3. Profitability by Market Segments
18.1.6.4. Sales Footprint
18.1.6.5. Strategy Overview
18.1.6.5.1. Marketing Strategy
18.1.7. Thermo Fisher Scientific
18.1.7.1. Overview
18.1.7.2. Product Portfolio
18.1.7.3. Profitability by Market Segments
18.1.7.4. Sales Footprint
18.1.7.5. Strategy Overview
18.1.7.5.1. Marketing Strategy
18.1.8. Adrenas Therapeutics, Inc.
18.1.8.1. Overview
18.1.8.2. Product Portfolio
18.1.8.3. Profitability by Market Segments
18.1.8.4. Sales Footprint
18.1.8.5. Strategy Overview
18.1.8.5.1. Marketing Strategy
18.1.9. Alder Biopharmaceuticals, Inc.
18.1.9.1. Overview
18.1.9.2. Product Portfolio
18.1.9.3. Profitability by Market Segments
18.1.9.4. Sales Footprint
18.1.9.5. Strategy Overview
18.1.9.5.1. Marketing Strategy
18.1.10. Zydus Lifesciences Ltd.
18.1.10.1. Overview
18.1.10.2. Product Portfolio
18.1.10.3. Profitability by Market Segments
18.1.10.4. Sales Footprint
18.1.10.5. Strategy Overview
18.1.10.5.1. Marketing Strategy
19. Assumptions & Acronyms Used
20. Research Methodology
Healthcare
March 2024
REP-GB-1664
324 pages
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