Cirrhosis Management Market Snapshot (2023 to 2033)

Valued at USD 725 million in 2023, the global market for cirrhosis management is likely to exhibit a CAGR of 3.8% during the forecast period, reaching USD 1,052.3 million by 2033. The market exhibited a compounded growth rate of 2.7% from 2018 to 2022. Expansion of the market can be attributed to the increasing incidences of liver cirrhosis due to rise in the hepatitis infections across the globe.

Data Points Key Statistics
Expected Base Year Value (2022) USD 701.8 million
Projected Market Value (2023) USD 725 million
Anticipated Forecast Value (2033) USD 1,052.3 million
Estimated Growth Rate (2023 to 2033) 3.8%

Cirrhosis is a late-stage result of liver disease and its complications. Common causes of Cirrhosis include alcohol abuse, hepatitis, and nonalcoholic fatty liver disease. Treatment and Management of Cirrhosis depends on the cause of the disease and how much damage exists. Liver transplantation may be an option if one’s liver is failing, due to disease.

As per the National Center for Biotechnology Information (NCBI), liver disease claims about 2 million deaths globally, every year. Currently, Cirrhosis is the 11th most cause of death. Due to aggravating situation, players in the market are taking various initiatives to tackle the worsening condition, which is expected to benefit the industry in the coming time.

In September 2019, Versantis raised a Series B of € 14.6 Million to develop its treatment for late-stage liver cirrhosis in a phase II trial. Post the II trial, the company announced that it is projected to use the funds to launch a phase IIa trial of the treatment in early 2020. Such factors are expected to benefit the cirrhosis management market in the forecast period.

Increasing incidences of liver cirrhosis due to rise in the hepatitis infections across the globe is one of the major factors that is expected to accelerate the growth of the global Cirrhosis Management Market over the analysis period.

On the contrary, the high cost associated with drug development is one of the major factors that is expected to hinder the growth of the cirrhosis management market during the forecast period.

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Which Are Some Prominent Drivers Spearheading Cirrhosis Management Market Growth?

The increase in the occurrence of liver cirrhosis due to the rise in hepatitis infections is one of the major factors that is anticipated to boost the growth of the global liver cirrhosis management market during the forecast period.

The rise in the number of people suffering from liver cirrhosis can be attributed to rapidly changing lifestyles such as an increase in alcohol consumption and an unbalanced diet. Hence, the rise in the prevalence of the disease is projected to fuel the growth of the global market during the forecast period.

According to the National Center for Biotechnology Information (NCBI), around 2 billion people consume alcohol worldwide, and upwards of 75 million are diagnosed with alcohol-use disorders and are at risk of alcohol-associated liver disease. Nearly 2 billion adults are obese or overweight and over 400 million have diabetes; both of which are risk factors for non-alcoholic fatty liver disease and hepatocellular carcinoma.

An increase in awareness programs and a rise in research & development investment for the development of new drug molecules are expected to augment the global liver cirrhosis management market in the forthcoming years. In addition, the rise in government-driven initiatives in the field of liver cirrhosis treatment is another factor that is expected to propel the global market shortly.

According to WHO, alcohol consumption is expected to cause 20% to 50% of liver cirrhosis cases. Also, the increasingly obese populace is expected to grow the risk of non-alcoholic fatty liver disease caused due to build-up of fat in the liver. Other vital factors contributing to the market growth include increased R&D, growing public awareness, and expanding geriatric population.

The increasing initiative of players to launch innovative tools is projected to be an effective factor in developing the market. For instance, in March 2022, Echosens, a high-tech company offering the FibroScan ® portfolio of solutions, announced the launch of FibroScan GO, a cost-effective tool for screening lover health and improving liver health management at the point of care for primary care practices. Attributed to such factors, the market is anticipated to grow significantly in the forecast period.

What Are the Challenges Faced by the Cirrhosis Management Industry?

Stringent regulatory approvals and delayed approvals for novel drugs and vaccines are one of the major factors that are anticipated to impede the growth of the cirrhosis management market during the forecast period. Also, side effects associated with products (fever, depression, and fatigue) is another vital factor that is expected to hamper the market growth in the coming time.

Moreover, the high cost associated with drug development is also a major factor that is expected to limit the growth of the cirrhosis management market over the analysis period. However, ongoing research studies and clinical trials for the treatment of liver disease are expected to act as a significant counter to the hampering causes and propel market growth in the coming time.

For instance, in March 2022, Siemens Healthineers launched Enhanced Liver Fibrosis (ELF) Test in the United States. It provides clinical access to the minimally invasive prognostic tool. Thus, the market is likely to expand significantly in the coming time.

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Why Is North America Emerging as An Opportunistic Cirrhosis Management Market?

Region North America
Market Share % (2022) 39.2%

In terms of regional platforms, North America holds the largest market share in the Cirrhosis Management market. The region gained a market share of 39.2% share in 2022. Developed nations like the United States, Canada, and others are expected to make the maximum contribution to strengthen the growth of the cirrhosis management industry. Domination of the region can be attributed to the presence of major players like Astellas Pharma Inc., Mylan, AbbVie Inc., Merck & Co., Inc., and others.

Ongoing development in the field is anticipated to offer significant results to the market. For instance, in December 2019, Gilead Sciences, Inc. announced topline results from the 48-week, Phase 2 ATLAS study of combination and monotherapy investigational treatments for advanced fibrosis due to Nonalcoholic Steatohepatitis (NASH).

The study resulted in the improvement of various measures of fibrosis and liver injury with the investigational first cost at and cilofexor. Attributed to such factors, the market in North America is expected to develop significantly in the forecast period.

Moreover, a favorable reimbursement scenario, an increase in research and development investments in pharmaceutical companies & research institutes for new drug development, and the presence of major players in the region are some major factors that are expected to fuel the market growth during the forecast period.

How Is Europe Contributing to the Growth of the Cirrhosis Management Market?

Region Europe
Market Share % (2022) 26.7%

According to Future Market Insights, Europe is expected to hold significant growth opportunities for cirrhosis management and reached a share of 26.7% in 2022.

According to the WHO, about 1.8% of all deaths in Europe are caused due to liver cirrhosis. Continuous efforts taken by the players in the market are likely to provide a significant boost to market growth in the coming time. For instance, in March 2021, A-Tango Consortium, a five-year project that receives funding from European Union’s Horizon 2020, was launched.

A-Tango Consortium will perform Phase II clinical studies of an innovative therapeutic strategy that targets inflammation and improves liver regeneration, the novel therapy is called G-TAK. Owing to such innovations in the region, the European market is anticipated to augment significantly in the forecast period.

Europe is likely to be the second largest market for liver cirrhosis treatment during the forecast period, owing to a rise in awareness about new treatment options and a developed regulatory framework in the region.

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Where Does Asia-Pacific Region Stand in The Cirrhosis Management Market?

Countries Market Forecast % (2023 to 2033)
China 4.3%
India 4.1%

According to Future Market Insights, Asia-Pacific is expected to grow with lucrative growth opportunities for the cirrhosis management industry.

Asia-Pacific is anticipated to witness notable growth, owing to a rise in research and development activities, a surge in liver diseases, unmet medical demands, and an increase in investments in the healthcare sector in the region.

Moreover, an increase in the consumption of alcohol, an unhealthy lifestyle leading to obesity & weight gain, the presence of key players, and a rise in healthcare expenditure in the region are some of the major factors that are anticipated to augment the growth of the cirrhosis management market over the analysis period.

In addition, the rise in the prevalence of liver diseases and improving healthcare infrastructure are other factors propelling the market growth in the region.

How Is Middle East & Africa Contributing to the Growth of the Cirrhosis Management Market?

According to Future Market Insights, the Middle East & Africa are expected to provide significant growth opportunities for the cirrhosis management industry.

The Middle East & Africa is expected to have significant growth in the cirrhosis management industry during the forecast period. The rising patient population suffering from liver cirrhosis is one of the major factors that is anticipated to escalate the market growth in the region.

The region is projected to have lucrative growth opportunities, attributed to the rapidly developing healthcare amenities among Saudi Arabia, Oman, and Qatar. Over 200,000 deaths took place in Sub-Saharan Africa due to liver diseases resulting in liver cirrhosis. More than 80% of Africa’s liver disease burden is due to endemic blood-borne virus infections like HIV, hepatitis B, and hepatitis C.

Additionally, the market Middle East & Africa is anticipated to expand at a steady pace, attributed to the presence of rapidly developing economies and evolving healthcare infrastructure in these regions.

Role Of Start-Ups in the Cirrhosis Management Market

There are many prominent market players in the Cirrhosis Management Market such as Galea Therapeutics, Akero Therapeutics, Inorbit Therapeutics, Ochre Bio, Ezra, Jetra Therapeutics, Moderna Therapeutics, Translate Bio, Promethera Biosciences, and AgomAb Therapeutics, among others, which are working hand-in-hand to provide the best-in-class Cirrhosis Management for enhancing the global arena.

However, there are many global start-ups in the Cirrhosis Management Market, that are stepping forward in matching the requirements of the Cirrhosis Management domain.

Founded in 2017, Akero Therapeutics is a clinical-stage biopharmaceutical company focused on delivering transformational medicines to patients with high unmet medical needs. The company aims to advance its lead program efruxifermin (EFX), to provide a powerful new treatment for patients with NASH, a disease for which there are currently no marketed therapies.

Market Competition

Some of the key participants present in the global Cirrhosis Management market include Theravance Biopharma R&D, Alliancells Bioscience Corporation Limited, B. Braun Medical Inc., Conatus Pharmaceuticals Inc., Merck Sharp & Dohme Corp., Stempeutics Research Pvt Ltd, Epic Research & Diagnostics, Inc., Inc., and NovaShunt AG among others.

Attributed to the presence of such a high number of participants, the market is highly competitive. While global players such as Theravance Biopharma R&D, Alliancells Bioscience Corporation Limited, and B. Braun Medical Inc., account for a considerable market size, several regional-level players are also operating across key growth regions, particularly in North America.

Recent Key Developments in the Market Include

  • In February 2021, B.Braun Medical Inc., an eminent in infusion therapy and pain management, announced that it received approval from the United States FDA for the first and only Acetaminophen Injection available in various doses. Acetaminophen Injection contains acetaminophen, which has been associated with cases of acute liver failure, resulting in liver transplant, and death.
  • In September 2021, Merck (MSD) announced that its antibody Keytruda met the primary endpoint of overall survival (OS) in Phase III KEYNOTE-394 clinical trial in Asian patients with advanced hepatocellular carcinoma (HCC), the most common form of primary liver cancer.

Report Scope

Report Attributes Details
Growth Rate 3.8% CAGR from 2023 to 2033
Market Value in 2023 USD 725 million
Market Value in 2033 USD 1,052.3 million
Base Year for Estimation 2022
Historical Data 2018 to 2022
Forecast Period 2023 to 2033
Quantitative Units USD million for Value
Report Coverage Revenue Forecast, Volume Forecast, Company Ranking, Competitive Landscape, Growth Factors, Trends and Pricing Analysis
Segments Covered Treatment, Disease Indication, End User, Region
Regions Covered North America; Latin America; Europe; Asia Pacific; Middle East & Africa
Key Countries Profiled The United States, Canada, Brazil, Mexico, Germany, The United Kingdom, France, Spain, Italy, China, Japan, South Korea, Malaysia, Singapore, Australia, New Zealand, GCC, South Africa, Israel
Key Companies Profiled B. Braun Medical Inc.; Alliancells Bioscience Corporation Ltd.; Histogen Inc.; Stempeutics Research Pvt. Ltd.; Epic Research & Diagnostics Inc.; Theravance Biopharma R&D Inc.; Sequana Medical AG
Customization Scope Available upon Request

Key Segments Profiled in the Cirrhosis Management Industry Survey

By Treatment:

  • Treating Cirrhosis Causes
  • Antiviral Medications for Hepatitis B & C
  • Corticosteroids
  • Symptomatic Treatment
  • Analgesics
  • Treatment of Portal Hypertension (Beta-Blockers, Nitrates)
  • Treatment of Edema and Ascites (Diuretics, Antibiotics)
  • Avoid Complications
  • Banding Procedures/Band Ligation of Varics
  • Dialysis
  • Treatment of Osteoporosis
  • Vaccination for Flu and Other Complications
  • Liver Transplantation

By Disease Indication:

  • Alcoholic Liver
  • Non-Alcoholic Liver

By End User:

  • Hospitals
  • Ambulatory Surgical Centers
  • Research Institutes
  • Dialysis Centers
  • Clinics
  • Other Settings

By Region:

  • North America
  • Latin America
  • Europe
  • Asia Pacific
  • Middle East & Africa

Frequently Asked Questions

Which are the Key Asian Countries in the Cirrhosis Management Market?

The leading Asian nations in the market for cirrhosis management are China, India, Japan, and South Korea.

Which Industry is the Key Consumer of the Cirrhosis Management Market?

The primary consumer of the cirrhosis management market is the healthcare sector.

How much can the Cirrhosis Management Market grow by 2033 in China and India?

The cirrhosis management market growth is predicted to be 4.3% in China and 4.1% in India by 2033

What is the Current Market Valuation of the Cirrhosis Management Market?

The cirrhosis management market is currently valued at USD 1052.3 million.

How Big will be the Cirrhosis Management Market by 2033?

Cirrhosis management is anticipated to be worth USD 1,052.3 million by 2033.

Table of Content
	1. Executive Summary
	2. Market Overview
	3. Market Background
	4. Global Market Analysis 2018 to 2022 and Forecast, 2023 to 2033
	5. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Treatment
		5.1. Treating Cirrhosis Causes
		5.2. Antiviral Medications for Hepatitis B & C
		5.3. Corticosteroids
		5.4. Symptomatic Treatment
		5.5. Analgesics
		5.6. Treatment of Portal Hypertension
		5.7. Treatment of Edema and Ascites
		5.8. Avoid Complications
		5.9. Banding Procedures/Band Ligation of Varics
		5.10. Dialysis
		5.11. Treatment of Osteoporosis
		5.12. Vaccination for Flu and Other Complications
		5.13. Liver Transplantation
	6. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Disease Indication
		6.1. Alcoholic Liver
		6.2. Non-Alcoholic Liver
	7. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By End User
		7.1. Hospitals
		7.2. Ambulatory Surgical Centers
		7.3. Research Institutes
		7.4. Dialysis Centers
		7.5. Clinics
		7.6. Other Settings
	8. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Region
		8.1. North America
		8.2. Latin America
		8.3. Western Europe
		8.4. Eastern Europe
		8.5. South Asia and Pacific
		8.6. East Asia
		8.7. Middle East and Africa
	9. North America Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
	10. Latin America Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
	11. Western Europe Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
	12. Eastern Europe Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
	13. South Asia and Pacific Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
	14. East Asia Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
	15. Middle East and Africa Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
	16. Key Countries Market Analysis
	17. Market Structure Analysis
	18. Competition Analysis
		18.1. B. Braun Medical Inc.
		18.2. Alliancells Bioscience Corporation Ltd.
		18.3. Histogen Inc.
		18.4. Stempeutics Research Pvt. Ltd.
		18.5. Epic Research & Diagnostics Inc.
		18.6. Theravance Biopharma R&D Inc.
		18.7. Sequana Medical AG
		18.8. NovaShunt AG
		18.9. Conatus Pharmaceuticals Inc.
		18.10. Merck Sharp & Dohme Corp.
	19. Assumptions & Acronyms Used
	20. Research Methodology
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