Bone Regeneration Market Outlook (2023 to 2033)

The global bone regeneration market is set to witness a valuation of US$ 5,380.75 million in 2023, and further expand at a CAGR of 3.8% to reach US$ 7,827.8 million by 2033. In terms of product type, bone graft substitutes led the market with a share of 81.2% in 2022.

The need for reconstructive surgery coupled with the prevalence of bone diseases across the globe has improved the demand for bone regenerative techniques. Statistics show that nearly 10% of men and 18% of women above 60 years have symptomatic osteoarthritis. Apart from this, a massive spike in bone injuries and hip fractures, especially among sports enthusiasts, has resulted in increased demand for bone regeneration surgeries.

Alternatives to bone grafts are used to cure delayed fracture unions, fuse the spine, repair bone abnormalities, and fill cavities brought on by a variety of factors. The substance is derived from a range of sources, including synthetics, bone void fillers, bone morphogenetic proteins, demineralized bone matrix, autografts, allografts, and others.

Globally, pediatric deformity, degenerative diseases, musculoskeletal oncology, spinal deformity, and cases of trauma and injury comprise the bulk of orthopedic problems. These problems are especially noticeable in developing economies such as India, China, and Brazil.

The market for bone regeneration is hence predicted to expand as more people develop musculoskeletal problems or disorders. The global market is expected to grow at a CAGR of 3.8% over the forecast period.

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What are the Key Opportunities for Bone Regeneration Kits Manufacturers?

Degenerative joint illnesses are becoming more common, which is aiding the growth of the industry. In the absence of treatment for the illness, numerous osteoarthritis patients develop extensive joint deterioration. Surgery utilizing bone replacements and transplants is essential to halt osteoarthritis-related progressive joint degeneration. Improvements in biomaterial and tissue engineering, according to the American College of Rheumatology, create new opportunities for incorporating surgical techniques in osteoarthritis.

According to healthcare professionals, the body's natural bone-healing mechanisms are aided by low-level electrical fields. Currently, this application is using the same technology. Researchers are leveraging advanced healthcare technologies to make additional strides, such as developing new strategies for promoting bone regeneration or making enhancements to the current devices.

Further, with a growing number of knee surgeries, healthcare professionals are developing advanced procedures and techniques to make the procedure less invasive and to increase the healing time. As per the American Academy of Orthopaedic Surgeons, over 6 million have undergone total knee arthroplasty in 2010 and the number has risen dramatically over the past decade.

For instance, in August 2022, OSSIO Inc., a leading orthopedic fixation technology company announced the launch and first commercial use of OSSIOfiber suture anchors in the USA This is accessible and can be used as bio-integrative implants in foot/ankle, and knee, shoulder, and elbow surgery.

What are the Factors Restraining Demand for Bone Regeneration?

Patients with non-union or delayed union of a bone fracture are usually advised to try traditional physiotherapy, yoga, or Ayurveda treatments. Several reviews on the therapy of fractures have incorrectly classed electrical and ultrasonic treatment as contraindications. Chiropractors represent a huge threat to the industry's ability to continue running as they are the leading alternative medical profession. The emergence of more potent alternative therapies hinder the growth of the bone regeneration industry.

Even though various research is being carried out to evaluate the efficacy of bone growth stimulator devices, the amount of scientific data currently accessible is insufficient to address their magnitude. According to an IJO review, it is challenging to do meta-analyses on the effectiveness of bone growth stimulator devices due to the variability of the clinical study designs for such devices.

With robust research and development, numerous research programs are attempting to solve device-related constraints. However, there are several shortcomings with the various devices on the market, and they must adhere to strict rules set forth by the regulatory bodies of distinct nations. The device is inadequate in several areas, including the shelf life and biocompatibility of the materials.

Attributes Details
Bone Regeneration Market CAGR (2023 to 2033) 3.8%
Bone Regeneration Market Size (2023) US$ 5,380.75 million
Bone Regeneration Market Size (2033) US$ 7,827.8 million
Sabyasachi Ghosh
Sabyasachi Ghosh

Principal Consultant

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Sales Analysis of Bone Regeneration from 2018 to 2022 Vs Market Outlook for 2023 to 2033

As per Future Market Insights (FMI), the bone regeneration market held approximately 13.3% of the overall US$ 37,200 million global orthopedics market in 2021. The bone regeneration industry expanded at a CAGR of 2.4% from 2018 to 2022 due to the increasing incidence of bone fractures and delayed bone healing.

Fractures are treated using a variety of techniques, such as surgery, amputations, allografts, and synthetic bone grafts. Low-intensity ultrasound stimulation and electrical bone growth stimulation are two examples of non-invasive treatments.

These devices speed up the healing process and are approved by regulatory authorities such as the United States Food and Drug Administration (FDA). Additionally, the reimbursement guidelines for bone growth stimulators have been updated by CMS and Medicare. Higher adoption rates of non-invasive techniques have also resulted in cost-effective methods, promoting the adoption of bone regenerative techniques.

Hence, players are introducing advanced products and technological innovations to leverage untapped market opportunities. Top manufacturers of bone regenerations products are expanding the value chain to integrate into the market of developing economies.

The increasing prevalence of patients with one or more comorbidities, such as degenerative joint diseases, osteoporosis, osteoarthritis, etc., make the bones brittle and susceptible to fractures and delayed healing. This is expected to be a prominent driver of the global bone regeneration sector in the coming years.

Regional Analysis

Country Market Share (2022)
United States 25.5%
Germany 8.6%
Japan 3.3%

What Makes the United States the Leading Market for Bone Regeneration?

The USA dominated the North American market with a total share of about 73.7% in 2021 and is expected to experience the same growth over the forecast period. The USA is considered to be the most attractive market due to the increased prevalence of joint illnesses, resulting in an increase in surgical treatments. The market for bone regeneration is expanding as a result of significant investment in Research and Development activities and the introduction of new products in the area.

According to the American Academy of Orthopedic Surgeons, in the USA by 2030, the number of total knee arthroplasty surgeries is expected to reach 3 million. Around 4.3 million spinal fusions are performed in the United States every year. This is expected to create lucrative growth prospects in the United States bone regeneration business over the upcoming decade.

Why is Germany Considered a Lucrative Market in Europe?

Germany is set to exhibit a CAGR of nearly 3.7% in the Europe market during the forecast period. Growth is primarily underpinned by increasingly available customized bone grafts and substitute treatments.

In Germany, 17.9% of adults over 18 reported having osteoarthritis, with women experiencing a higher frequency (21.8%) than men (13.9%), according to 2017 data from The Journal of Health Monitoring. On the other hand, favorable reimbursement policies provided by organizations are pushing patients to opt for cost-effective bone regenerative treatments, fueling growth in the market.

How is the China Bone Regeneration Industry Faring?

China held a 50.3% share in the East Asia bone regeneration market in 2022 and is projected to increase at a CAGR rate of 4.6% during the forecast period. With the developing healthcare system in China, healthcare professionals are witnessing a paradigm shift in regenerative medicine technology.

The advent of 3D structures and non-invasive bone grafting procedures has transformed the face of China's bone regeneration market. Further, with the growing prevalence of bone disorders, even in children and adolescents has led to an uptake in bone regenerative product sales. Backed by these factors, the demand in China is expected to surge over the forecast period.

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Category-wise Insights

Which Bone Regeneration Product is Driving Market Growth?

Bone graft substitutes project lucrative growth at a CAGR of 4.1% during the forecast period, and led the market with a share of around 81.2% in 2022. Bone graft substitutes are used to repair delayed fracture unions, fuse the spine, fill voids caused by a variety of conditions, and bridge bone abnormalities. The bone graft substitute has a high likelihood of successful bone fusion making it the most profitable product available on the market for bone regeneration.

Which is the Leading Application in the Bone Regeneration Market?

Trauma cases held a revenue share of 22.8% in 2022 and are expected to increase at a CAGR of 2.6% by 2033. The leading cause of death for those under the age of 65 is trauma. Additionally, injury-related mortality is a significant global public health burden, driving the market. Emergency rooms are a sensitive indicator of the impact generated by traumatic injury. The market is anticipated to grow between 2023 and 2033 as bone graft substitute plays a significant role in trauma cases.

Which End User Benefits the Most from the Employment of Bone Regeneration?

Due to the availability of products and therapies for treating joint problems, hospitals currently hold the top position in the bone regeneration market with a 49.1% market share. Throughout the forecast period, they are expected to maintain this position while growing at a CAGR of 3.6%. As more patients are admitted to hospitals for the treatment of musculoskeletal injuries and diseases, the market for bone regeneration is anticipated to expand.

Growth in the market is facilitated by the availability of cutting-edge medical equipment with better efficiency and technology, as well as by qualified personnel and healthcare experts. Numerous patients are drawn to hospitals because of the existence of cutting-edge medical technology to receive treatment and experience the most satisfaction and comfort. As a result, hospitals dominate the market for bone regeneration compared to other end users.

Competitive Landscape

Key competitors in the bone regeneration sector are focusing on collaborations, product launches, and expansion to achieve a dominant position in the market. With the use of these strategies, market participants can increase the number of products they offer and their market penetration. As a result, they have seen a rise in their overall revenue share in the global market for bone regeneration.

Given below are a few examples of the key strategies followed by the manufacturers:

  • In March 2022, Biocomposites, a multinational maker of medical products, and Zimmer Biomet agreed to a multiyear distribution agreement for Genex Bone Graft Substitute in the orthopedic market in the USA This product features a new mixing mechanism and delivery options.
  • In February 2020, Integra LifeSciences launched the AmnioExcel® Plus placental allograft membrane.

Key Players

  • Medtronic plc.
  • Stryker Corporation
  • DePuy Synthes Inc.
  • Integra Lifesciences Holdings Corporation
  • Zimmer Biomet HoldingsInc.
  • Xtant Medical HoldingsInc.
  • Arthrex Inc.
  • Baxter International Inc.
  • Musculoskeletal Transplant Foundation
  • Smith & NephewInc.
  • Orthofix HoldingsInc.
  • NuvasiveInc.
  • Allosaurus
  • NovaBone ProductsLLC
  • BonAlive Biomaterials Ltd.
  • Sigma Graft Biomaterials
  • RTI Surgical
  • Institut Straumann AG
  • ExactechInc
  • A.B. Dental Devices Ltd
  • Geistlich Pharma AG
  • BMT Group
  • Osstem Implant

Key Segments

By Product:

  • Bone Grafts Substitutes
    • Allografts
      • Demineralized Bone Matrix(DBM)
      • Others
    • Xenograft
    • Autografts
    • Synthetic Bone Graft
    • Bone Morphogenetic Protein(BMP)
  • Bone Growth Stimulators
    • Non-Invasive Electrical Bone Growth Stimulators
    • Invasive Electrical Bone Growth Stimulators

By Application:

  • Osteoarthritis (OA)
  • Osteoporosis
  • Rheumatoid Arthritis (RA)
  • Spinal Disorders
  • Dentistry
  • Craniomaxillofacial (CMF)
  • Trauma Cases

By Age Group:

  • Pediatric
  • Adults
  • Geriatric

By End User:

  • Hospitals
  • Orthopedic Clinics
  • Ambulatory Surgical Centers

By Region:

  • North America
  • Latin America
  • Europe
  • South Asia
  • East Asia
  • Oceania
  • The Middle East and Africa (MEA)

Frequently Asked Questions

What is the Bone Regeneration market CAGR for 2033?

The bone regeneration market CAGR for 2033 is 3.8%.

How Big Will the Bone Regeneration Market by 2033?

The market is estimated to reach US$ 7,827.8 million by 2033.

Which are the Top Three Countries Leading the Market?

North America, Europe, and Asia-Pacific are the top 3 countries leading the market.

What is Current Market Valuation?

The market is estimated to secure a valuation of US$ 5,380.75 million in 2023.

Which are the Key Asian Countries in the Bone Regeneration Market?

India, Japan, and China dominate the Asian market.

Table of Content

1. Executive Summary

    1.1. Global Market Outlook

    1.2. Demand-side Trends

    1.3. Supply-side Trends

    1.4. Technology Roadmap Analysis

    1.5. Analysis and Recommendations

2. Market Overview

    2.1. Market Coverage / Taxonomy

    2.2. Market Definition / Scope / Limitations

3. Market Background

    3.1. Market Dynamics

        3.1.1. Drivers

        3.1.2. Restraints

        3.1.3. Opportunity

        3.1.4. Trends

    3.2. Scenario Forecast

        3.2.1. Demand in Optimistic Scenario

        3.2.2. Demand in Likely Scenario

        3.2.3. Demand in Conservative Scenario

    3.3. Opportunity Map Analysis

    3.4. Investment Feasibility Matrix

    3.5. PESTLE and Porter’s Analysis

    3.6. Regulatory Landscape

        3.6.1. By Key Regions

        3.6.2. By Key Countries

    3.7. Regional Parent Market Outlook

4. Global Market Analysis 2018 to 2022 and Forecast, 2023 to 2033

    4.1. Historical Market Size Value (US$ Million) Analysis, 2018 to 2022

    4.2. Current and Future Market Size Value (US$ Million) Projections, 2023 to 2033

        4.2.1. Y-o-Y Growth Trend Analysis

        4.2.2. Absolute $ Opportunity Analysis

5. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Product

    5.1. Introduction / Key Findings

    5.2. Historical Market Size Value (US$ Million) Analysis By Product, 2018 to 2022

    5.3. Current and Future Market Size Value (US$ Million) Analysis and Forecast By Product, 2023 to 2033

        5.3.1. Demineralized Bone Matrix(DBM)

        5.3.2. Xenograft

        5.3.3. Autografts

        5.3.4. Synthetic Bone Graft

        5.3.5. Bone Morphogenetic Protein(BMP)

        5.3.6. Non-Invasive Electrical Bone Growth Stimulators

        5.3.7. Invasive Electrical Bone Growth Stimulators

    5.4. Y-o-Y Growth Trend Analysis By Product, 2018 to 2022

    5.5. Absolute $ Opportunity Analysis By Product, 2023 to 2033

6. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Application

    6.1. Introduction / Key Findings

    6.2. Historical Market Size Value (US$ Million) Analysis By Application, 2018 to 2022

    6.3. Current and Future Market Size Value (US$ Million) Analysis and Forecast By Application, 2023 to 2033

        6.3.1. Osteoarthritis (OA)

        6.3.2. Osteoporosis

        6.3.3. Rheumatoid Arthritis (RA)

        6.3.4. Spinal Disorders

        6.3.5. Dentistry

        6.3.6. Craniomaxillofacial (CMF)

        6.3.7. Trauma Cases

    6.4. Y-o-Y Growth Trend Analysis By Application, 2018 to 2022

    6.5. Absolute $ Opportunity Analysis By Application, 2023 to 2033

7. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Age Group

    7.1. Introduction / Key Findings

    7.2. Historical Market Size Value (US$ Million) Analysis By Age Group, 2018 to 2022

    7.3. Current and Future Market Size Value (US$ Million) Analysis and Forecast By Age Group, 2023 to 2033

        7.3.1. Pediatric

        7.3.2. Adults

        7.3.3. Geriatric

    7.4. Y-o-Y Growth Trend Analysis By Age Group, 2018 to 2022

    7.5. Absolute $ Opportunity Analysis By Age Group, 2023 to 2033

8. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By End User

    8.1. Introduction / Key Findings

    8.2. Historical Market Size Value (US$ Million) Analysis By End User, 2018 to 2022

    8.3. Current and Future Market Size Value (US$ Million) Analysis and Forecast By End User, 2023 to 2033

        8.3.1. Hospitals

        8.3.2. Orthopedic Clinics

        8.3.3. Ambulatory Surgical Centers

    8.4. Y-o-Y Growth Trend Analysis By End User, 2018 to 2022

    8.5. Absolute $ Opportunity Analysis By End User, 2023 to 2033

9. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Region

    9.1. Introduction

    9.2. Historical Market Size Value (US$ Million) Analysis By Region, 2018 to 2022

    9.3. Current Market Size Value (US$ Million) Analysis and Forecast By Region, 2023 to 2033

        9.3.1. North America

        9.3.2. Latin America

        9.3.3. Western Europe

        9.3.4. Eastern Europe

        9.3.5. South Asia and Pacific

        9.3.6. East Asia

        9.3.7. Middle East and Africa

    9.4. Market Attractiveness Analysis By Region

10. North America Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country

    10.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022

    10.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033

        10.2.1. By Country

            10.2.1.1. USA

            10.2.1.2. Canada

        10.2.2. By Product

        10.2.3. By Application

        10.2.4. By Age Group

        10.2.5. By End User

    10.3. Market Attractiveness Analysis

        10.3.1. By Country

        10.3.2. By Product

        10.3.3. By Application

        10.3.4. By Age Group

        10.3.5. By End User

    10.4. Key Takeaways

11. Latin America Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country

    11.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022

    11.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033

        11.2.1. By Country

            11.2.1.1. Brazil

            11.2.1.2. Mexico

            11.2.1.3. Rest of Latin America

        11.2.2. By Product

        11.2.3. By Application

        11.2.4. By Age Group

        11.2.5. By End User

    11.3. Market Attractiveness Analysis

        11.3.1. By Country

        11.3.2. By Product

        11.3.3. By Application

        11.3.4. By Age Group

        11.3.5. By End User

    11.4. Key Takeaways

12. Western Europe Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country

    12.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022

    12.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033

        12.2.1. By Country

            12.2.1.1. Germany

            12.2.1.2. UK

            12.2.1.3. France

            12.2.1.4. Spain

            12.2.1.5. Italy

            12.2.1.6. Rest of Western Europe

        12.2.2. By Product

        12.2.3. By Application

        12.2.4. By Age Group

        12.2.5. By End User

    12.3. Market Attractiveness Analysis

        12.3.1. By Country

        12.3.2. By Product

        12.3.3. By Application

        12.3.4. By Age Group

        12.3.5. By End User

    12.4. Key Takeaways

13. Eastern Europe Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country

    13.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022

    13.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033

        13.2.1. By Country

            13.2.1.1. Poland

            13.2.1.2. Russia

            13.2.1.3. Czech Republic

            13.2.1.4. Romania

            13.2.1.5. Rest of Eastern Europe

        13.2.2. By Product

        13.2.3. By Application

        13.2.4. By Age Group

        13.2.5. By End User

    13.3. Market Attractiveness Analysis

        13.3.1. By Country

        13.3.2. By Product

        13.3.3. By Application

        13.3.4. By Age Group

        13.3.5. By End User

    13.4. Key Takeaways

14. South Asia and Pacific Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country

    14.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022

    14.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033

        14.2.1. By Country

            14.2.1.1. India

            14.2.1.2. Bangladesh

            14.2.1.3. Australia

            14.2.1.4. New Zealand

            14.2.1.5. Rest of South Asia and Pacific

        14.2.2. By Product

        14.2.3. By Application

        14.2.4. By Age Group

        14.2.5. By End User

    14.3. Market Attractiveness Analysis

        14.3.1. By Country

        14.3.2. By Product

        14.3.3. By Application

        14.3.4. By Age Group

        14.3.5. By End User

    14.4. Key Takeaways

15. East Asia Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country

    15.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022

    15.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033

        15.2.1. By Country

            15.2.1.1. China

            15.2.1.2. Japan

            15.2.1.3. South Korea

        15.2.2. By Product

        15.2.3. By Application

        15.2.4. By Age Group

        15.2.5. By End User

    15.3. Market Attractiveness Analysis

        15.3.1. By Country

        15.3.2. By Product

        15.3.3. By Application

        15.3.4. By Age Group

        15.3.5. By End User

    15.4. Key Takeaways

16. Middle East and Africa Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country

    16.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022

    16.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033

        16.2.1. By Country

            16.2.1.1. GCC Countries

            16.2.1.2. South Africa

            16.2.1.3. Israel

            16.2.1.4. Rest of MEA

        16.2.2. By Product

        16.2.3. By Application

        16.2.4. By Age Group

        16.2.5. By End User

    16.3. Market Attractiveness Analysis

        16.3.1. By Country

        16.3.2. By Product

        16.3.3. By Application

        16.3.4. By Age Group

        16.3.5. By End User

    16.4. Key Takeaways

17. Key Countries Market Analysis

    17.1. USA

        17.1.1. Pricing Analysis

        17.1.2. Market Share Analysis, 2022

            17.1.2.1. By Product

            17.1.2.2. By Application

            17.1.2.3. By Age Group

            17.1.2.4. By End User

    17.2. Canada

        17.2.1. Pricing Analysis

        17.2.2. Market Share Analysis, 2022

            17.2.2.1. By Product

            17.2.2.2. By Application

            17.2.2.3. By Age Group

            17.2.2.4. By End User

    17.3. Brazil

        17.3.1. Pricing Analysis

        17.3.2. Market Share Analysis, 2022

            17.3.2.1. By Product

            17.3.2.2. By Application

            17.3.2.3. By Age Group

            17.3.2.4. By End User

    17.4. Mexico

        17.4.1. Pricing Analysis

        17.4.2. Market Share Analysis, 2022

            17.4.2.1. By Product

            17.4.2.2. By Application

            17.4.2.3. By Age Group

            17.4.2.4. By End User

    17.5. Germany

        17.5.1. Pricing Analysis

        17.5.2. Market Share Analysis, 2022

            17.5.2.1. By Product

            17.5.2.2. By Application

            17.5.2.3. By Age Group

            17.5.2.4. By End User

    17.6. UK

        17.6.1. Pricing Analysis

        17.6.2. Market Share Analysis, 2022

            17.6.2.1. By Product

            17.6.2.2. By Application

            17.6.2.3. By Age Group

            17.6.2.4. By End User

    17.7. France

        17.7.1. Pricing Analysis

        17.7.2. Market Share Analysis, 2022

            17.7.2.1. By Product

            17.7.2.2. By Application

            17.7.2.3. By Age Group

            17.7.2.4. By End User

    17.8. Spain

        17.8.1. Pricing Analysis

        17.8.2. Market Share Analysis, 2022

            17.8.2.1. By Product

            17.8.2.2. By Application

            17.8.2.3. By Age Group

            17.8.2.4. By End User

    17.9. Italy

        17.9.1. Pricing Analysis

        17.9.2. Market Share Analysis, 2022

            17.9.2.1. By Product

            17.9.2.2. By Application

            17.9.2.3. By Age Group

            17.9.2.4. By End User

    17.10. Poland

        17.10.1. Pricing Analysis

        17.10.2. Market Share Analysis, 2022

            17.10.2.1. By Product

            17.10.2.2. By Application

            17.10.2.3. By Age Group

            17.10.2.4. By End User

    17.11. Russia

        17.11.1. Pricing Analysis

        17.11.2. Market Share Analysis, 2022

            17.11.2.1. By Product

            17.11.2.2. By Application

            17.11.2.3. By Age Group

            17.11.2.4. By End User

    17.12. Czech Republic

        17.12.1. Pricing Analysis

        17.12.2. Market Share Analysis, 2022

            17.12.2.1. By Product

            17.12.2.2. By Application

            17.12.2.3. By Age Group

            17.12.2.4. By End User

    17.13. Romania

        17.13.1. Pricing Analysis

        17.13.2. Market Share Analysis, 2022

            17.13.2.1. By Product

            17.13.2.2. By Application

            17.13.2.3. By Age Group

            17.13.2.4. By End User

    17.14. India

        17.14.1. Pricing Analysis

        17.14.2. Market Share Analysis, 2022

            17.14.2.1. By Product

            17.14.2.2. By Application

            17.14.2.3. By Age Group

            17.14.2.4. By End User

    17.15. Bangladesh

        17.15.1. Pricing Analysis

        17.15.2. Market Share Analysis, 2022

            17.15.2.1. By Product

            17.15.2.2. By Application

            17.15.2.3. By Age Group

            17.15.2.4. By End User

    17.16. Australia

        17.16.1. Pricing Analysis

        17.16.2. Market Share Analysis, 2022

            17.16.2.1. By Product

            17.16.2.2. By Application

            17.16.2.3. By Age Group

            17.16.2.4. By End User

    17.17. New Zealand

        17.17.1. Pricing Analysis

        17.17.2. Market Share Analysis, 2022

            17.17.2.1. By Product

            17.17.2.2. By Application

            17.17.2.3. By Age Group

            17.17.2.4. By End User

    17.18. China

        17.18.1. Pricing Analysis

        17.18.2. Market Share Analysis, 2022

            17.18.2.1. By Product

            17.18.2.2. By Application

            17.18.2.3. By Age Group

            17.18.2.4. By End User

    17.19. Japan

        17.19.1. Pricing Analysis

        17.19.2. Market Share Analysis, 2022

            17.19.2.1. By Product

            17.19.2.2. By Application

            17.19.2.3. By Age Group

            17.19.2.4. By End User

    17.20. South Korea

        17.20.1. Pricing Analysis

        17.20.2. Market Share Analysis, 2022

            17.20.2.1. By Product

            17.20.2.2. By Application

            17.20.2.3. By Age Group

            17.20.2.4. By End User

    17.21. GCC Countries

        17.21.1. Pricing Analysis

        17.21.2. Market Share Analysis, 2022

            17.21.2.1. By Product

            17.21.2.2. By Application

            17.21.2.3. By Age Group

            17.21.2.4. By End User

    17.22. South Africa

        17.22.1. Pricing Analysis

        17.22.2. Market Share Analysis, 2022

            17.22.2.1. By Product

            17.22.2.2. By Application

            17.22.2.3. By Age Group

            17.22.2.4. By End User

    17.23. Israel

        17.23.1. Pricing Analysis

        17.23.2. Market Share Analysis, 2022

            17.23.2.1. By Product

            17.23.2.2. By Application

            17.23.2.3. By Age Group

            17.23.2.4. By End User

18. Market Structure Analysis

    18.1. Competition Dashboard

    18.2. Competition Benchmarking

    18.3. Market Share Analysis of Top Players

        18.3.1. By Regional

        18.3.2. By Product

        18.3.3. By Application

        18.3.4. By Age Group

        18.3.5. By End User

19. Competition Analysis

    19.1. Competition Deep Dive

        19.1.1. Medtronic plc.

            19.1.1.1. Overview

            19.1.1.2. Product Portfolio

            19.1.1.3. Profitability by Market Segments

            19.1.1.4. Sales Footprint

            19.1.1.5. Strategy Overview

                19.1.1.5.1. Marketing Strategy

        19.1.2. Stryker Corporation

            19.1.2.1. Overview

            19.1.2.2. Product Portfolio

            19.1.2.3. Profitability by Market Segments

            19.1.2.4. Sales Footprint

            19.1.2.5. Strategy Overview

                19.1.2.5.1. Marketing Strategy

        19.1.3. DePuy Synthes Inc.

            19.1.3.1. Overview

            19.1.3.2. Product Portfolio

            19.1.3.3. Profitability by Market Segments

            19.1.3.4. Sales Footprint

            19.1.3.5. Strategy Overview

                19.1.3.5.1. Marketing Strategy

        19.1.4. Integra Lifesciences Holdings Corporation

            19.1.4.1. Overview

            19.1.4.2. Product Portfolio

            19.1.4.3. Profitability by Market Segments

            19.1.4.4. Sales Footprint

            19.1.4.5. Strategy Overview

                19.1.4.5.1. Marketing Strategy

        19.1.5. Zimmer Biomet HoldingsInc.

            19.1.5.1. Overview

            19.1.5.2. Product Portfolio

            19.1.5.3. Profitability by Market Segments

            19.1.5.4. Sales Footprint

            19.1.5.5. Strategy Overview

                19.1.5.5.1. Marketing Strategy

        19.1.6. Xtant Medical HoldingsInc.

            19.1.6.1. Overview

            19.1.6.2. Product Portfolio

            19.1.6.3. Profitability by Market Segments

            19.1.6.4. Sales Footprint

            19.1.6.5. Strategy Overview

                19.1.6.5.1. Marketing Strategy

        19.1.7. ArthrexInc.

            19.1.7.1. Overview

            19.1.7.2. Product Portfolio

            19.1.7.3. Profitability by Market Segments

            19.1.7.4. Sales Footprint

            19.1.7.5. Strategy Overview

                19.1.7.5.1. Marketing Strategy

        19.1.8. Baxter International Inc.

            19.1.8.1. Overview

            19.1.8.2. Product Portfolio

            19.1.8.3. Profitability by Market Segments

            19.1.8.4. Sales Footprint

            19.1.8.5. Strategy Overview

                19.1.8.5.1. Marketing Strategy

        19.1.9. Musculoskeletal Transplant Foundation

            19.1.9.1. Overview

            19.1.9.2. Product Portfolio

            19.1.9.3. Profitability by Market Segments

            19.1.9.4. Sales Footprint

            19.1.9.5. Strategy Overview

                19.1.9.5.1. Marketing Strategy

        19.1.10. Smith & NephewInc.

            19.1.10.1. Overview

            19.1.10.2. Product Portfolio

            19.1.10.3. Profitability by Market Segments

            19.1.10.4. Sales Footprint

            19.1.10.5. Strategy Overview

                19.1.10.5.1. Marketing Strategy

        19.1.11. Orthofix HoldingsInc.

            19.1.11.1. Overview

            19.1.11.2. Product Portfolio

            19.1.11.3. Profitability by Market Segments

            19.1.11.4. Sales Footprint

            19.1.11.5. Strategy Overview

                19.1.11.5.1. Marketing Strategy

        19.1.12. NuvasiveInc.

            19.1.12.1. Overview

            19.1.12.2. Product Portfolio

            19.1.12.3. Profitability by Market Segments

            19.1.12.4. Sales Footprint

            19.1.12.5. Strategy Overview

                19.1.12.5.1. Marketing Strategy

        19.1.13. Allosaurus

            19.1.13.1. Overview

            19.1.13.2. Product Portfolio

            19.1.13.3. Profitability by Market Segments

            19.1.13.4. Sales Footprint

            19.1.13.5. Strategy Overview

                19.1.13.5.1. Marketing Strategy

        19.1.14. NovaBone ProductsLLC

            19.1.14.1. Overview

            19.1.14.2. Product Portfolio

            19.1.14.3. Profitability by Market Segments

            19.1.14.4. Sales Footprint

            19.1.14.5. Strategy Overview

                19.1.14.5.1. Marketing Strategy

        19.1.15. BonAlive Biomaterials Ltd.

            19.1.15.1. Overview

            19.1.15.2. Product Portfolio

            19.1.15.3. Profitability by Market Segments

            19.1.15.4. Sales Footprint

            19.1.15.5. Strategy Overview

                19.1.15.5.1. Marketing Strategy

        19.1.16. Sigma Graft Biomaterials

            19.1.16.1. Overview

            19.1.16.2. Product Portfolio

            19.1.16.3. Profitability by Market Segments

            19.1.16.4. Sales Footprint

            19.1.16.5. Strategy Overview

                19.1.16.5.1. Marketing Strategy

        19.1.17. RTI Surgical

            19.1.17.1. Overview

            19.1.17.2. Product Portfolio

            19.1.17.3. Profitability by Market Segments

            19.1.17.4. Sales Footprint

            19.1.17.5. Strategy Overview

                19.1.17.5.1. Marketing Strategy

        19.1.18. Institut Straumann AG

            19.1.18.1. Overview

            19.1.18.2. Product Portfolio

            19.1.18.3. Profitability by Market Segments

            19.1.18.4. Sales Footprint

            19.1.18.5. Strategy Overview

                19.1.18.5.1. Marketing Strategy

        19.1.19. ExactechInc

            19.1.19.1. Overview

            19.1.19.2. Product Portfolio

            19.1.19.3. Profitability by Market Segments

            19.1.19.4. Sales Footprint

            19.1.19.5. Strategy Overview

                19.1.19.5.1. Marketing Strategy

        19.1.20. A.B. Dental Devices Ltd

            19.1.20.1. Overview

            19.1.20.2. Product Portfolio

            19.1.20.3. Profitability by Market Segments

            19.1.20.4. Sales Footprint

            19.1.20.5. Strategy Overview

                19.1.20.5.1. Marketing Strategy

20. Assumptions & Acronyms Used

21. Research Methodology

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