Biodefense Market Outlook

The global biodefense market size was valued at USD 16.31 billion in the year 2023 and is estimated to reach a revised size of USD 32.99 billion by 2033. This market is projected to expand at a CAGR of 7.3% during the analysis period. Increasing demand for vaccines, drugs, and medical devices creates opportunities for companies to expand their businesses and penetrate new markets.

Biological terrorism involves the deliberate release of viruses, bacteria, and other harmful germs capable of spreading epidemics and causing death. It has a detrimental impact on the economy because of the damage it causes to human health and the drain on human resources. Therefore, developed countries undertake a variety of efforts, as well as preventive measures, to strengthen their defense against these attacks.

Various countries maintain a constant supply of vaccines and biothreat detection technology to ensure the safety of their citizens. Government initiatives like this may help to accelerate the growth of the biodefense industry. It is possible to use biological toxins or infectious agents with malicious intentions, such as killing or infecting humans, animals, or the environment or even provoking biological warfare. In addition to living organisms such as bacteria, viruses, fungi, and toxins, several agents are used in bioterrorism.

By deliberately infecting and killing people, these agents can be used to cause social and economic turmoil. As a result of government initiatives, and increased government attention and funding towards biodefense strategies, the biodefense market is fueled by various factors. For example, the Department of Defense is modernizing its approach to develop medical countermeasures to protect warfighters from novel biological agents.

In the years to come, the scope of the biodefense market may be further expanded by increasing private investment. This is due to the occurrence of different viruses such as the flu, the Ebola virus, and the Zika virus.

Some technological advancements have been made in genetic engineering and biotechnology in the past few years. These advancements have enabled innovative approaches to combat these deadly, naturally occurring viruses that can be redesigned to cause additional harm. Moreover, these organisms are readily available, making biodefense an imperative aspect of countries around the world. The use of various biological agents, such as botulism, anthrax, and chemical and nuclear agents, has contributed to severe destruction as a result of bioterrorism.

Attributes Details
Biodefense Market Value (2023) USD 16.31 billion
Biodefense Market Expected Value (2033) USD 32.99 billion
Biodefense Market Projected CAGR (2023 to 2033) 7.3%

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Global Biodefense Market Historical Analysis (2017 to 2022) Vs. Forecast Outlook (2023 to 2033)

The global biodefense market expanded at 8.1% CAGR over the past 10 years. The market is anticipated to expand at a CAGR of close to 7.3% over the forthcoming decade.

Biodefense markets were positively impacted by the pandemic. As a result of the pandemic, numerous government and non-governmental agencies were required to coordinate their responses nationwide, as catastrophic biological events can result in significant human and economic losses. Since the pandemic promises huge potential for investment and income redistribution, there are many reasons to believe it is an intentional act of bioterrorism.

  • Short Term (2023 to 2026): As the market grows, it may provide new opportunities for companies developing and producing vaccines, diagnostics, and therapeutic products for the prevention and treatment of infectious diseases.
  • Medium Term (2026 to 2029): The market is driven by factors such as increasing government funding for research and development, growing concern over the threat of pandemics and bioterrorism, and advancements in biotechnology.
  • Long Term (2029 to 2033): The prominent advancement of biotechnology is leading to the development of new and more effective biodefense products, such as vaccines and diagnostic tests, providing opportunities for companies in the biodefense market.
Historical CAGR (2016 to 2022) 8.1%
Historical Market Value (2022) USD 15.20 billion
Forecast CAGR 7.3%

Factors Driving the Biodefense Market

Rise in Technological Advancements

Due to the rise of bioterrorism, prominent industry players have incorporated advances in biothreat detection systems. These advances aid in the identification of bacteria and viruses that may be beneficial to market growth during the analysis period. As a result, technological breakthroughs can have a beneficial influence on market growth. To secure the security and safety of the population, technologically sophisticated biothreat detection technologies are necessary, which can help boost the market's growth.

To detect pathogens in nanotechnology, forensics, and biodefense-related drug development, innovative technologies, including gene chips, are widely used. As a means of improving agricultural yields, synthetic biology is also contributing to market growth, as it improves agricultural yields.

Increase in Investments by Government for Defense Expenditure

It is one of the key factors driving the growth of the market that the threat of terrorism is growing along with an ever-increasing level of tension between nations. It is also contributing to biodefense market growth that governments across several nations are increasing their defense spending to improve both internal and external security.

For example, the United States Department of Defense (DoD) spent USD 718 billion in FY 2021, with the large category being operation and maintenance at USD 286 billion. Furthermore, government agencies are developing medical countermeasures for chemical, biological, nuclear, and radiological threats to minimize the adverse effects of these attacks.

The Rise in Demand for Vaccines

The development of novel vaccine technologies, such as vector technology, is expected to drive the growth of the biodefense market as they can provide rapid protection against pathogen attacks. In recent years, vaccines have been developed that can combat a wide variety of bioterrorism chemicals and can induce long-lasting immune responses.

Several countries are experiencing a surge in Ebola and Zika infections, resulting in a race to develop vaccines. The government spends a lot of money on vaccine research and development to make sure it is prepared for any bioterrorism attacks. Pharmaceutical companies operating in the biodefense market have a huge opportunity to expand since governments are always looking for ways to prevent bioterrorism.

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Category-wise Insights

Product Insights: The Anthrax Segment is expected to be the significant Contributor to the Market

In terms of products, the market is segmented into anthrax, smallpox, botulism, radiation/nuclear, and others. The anthrax segment held a prominent market share of 28.1% in 2023. Many factors contribute to the growth of the anthrax product segment. Some of these factors include the increase in anthrax outbreaks in humans, favorable government initiatives, and collaboration in research and development in the studied fields.

In July 2022, as reported by the media, 15 cases of cutaneous anthrax were linked to an anthrax outbreak in cattle in Sisak-Moslavina County following heavy rain, according to the European Centre for Disease Prevention and Control (ECDC) Communicable Disease Threat Report. Moreover, in July 2022, the Croatian Ministry of Agriculture issued an order containing measures to prevent the outbreak and spread of anthrax in the affected area. These measures include closures of affected areas, vaccinations of animals, and additional human prevention measures.

One of the most likely potential weapons used in a bioterrorist attack is Bacillus anthracis, a gram-positive bacterium that causes anthrax. Those spores are preferred because they can be easily released into the environment by adding them to food, water, powders, and sprays. The bacterium can persist in the environment for a long time and is easily found in nature (soil, plants, or water). As anthrax bacteria can be easily transmitted from one person to another, NCBI categorizes it as a tier-1 biological agent, which has the potential to cause a massive public health disaster.

In the field of countermeasures, anthrax remains a key focus. It has received a significant amount of funding for vaccine development. Many companies have developed anthrax vaccines, including Bioshield, which has received over USD 50 billion in funding since the September 11 attacks.

In recent years, many countries have seen a rise in infection cases caused by the Zika virus and Ebola virus. This has prompted many companies to compete to develop vaccines for these viruses. MVA-BN Filo, manufactured by Bavarian Nordic, is a vaccine against two filoviruses, Ebola and Marburg's diseases, currently in phase 3 clinical trials and collaborating with the United States NIAID for the same.

Region Wise: North America Dominates the Market

In 2023, North America accounted for 79% of the biodefense market and is expected to exhibit a significant growth rate. As a result of federal funding, technological advancements, and growing awareness, this market is projected to expand significantly in the forecast period. Key players in this region make it easy for the biodefense market to grow in 2023. Increased research and development in the studies field, as well as increasing government initiatives, are the primary growth factors in this market.

Regions Leading in Biodefense Market: Country-wise Analysis

The United States Biodefense Market Dominates North America Region

During the forthcoming years, the United States Biodefense Market is expected to dominate North America due to the growing importance of biodefense and increasing threats from harmful biological materials. Furthermore, the United States has well-established vaccine production facilities and is one of the region's most developed biodefense markets. Moreover, the United States government implements some initiatives that help them strengthen security against bioterrorism attacks. For example, the government plans a pandemic influenza program and a program to fight infectious diseases.

The regional market forecast may also be influenced by other factors, such as the growing adoption of technologically advanced products and the increasing awareness of biodefense among individuals.

A leadership structure and a comprehensive strategy were established in National Security Presidential Memorandum 14 (NSPM-14) to coordinate all biodefense efforts associated with the U.S. Government. The combination of the strategy and memorandum enabled the annual budget planning process to identify and connect gaps for the first time.

Why is Germany’s Biodefense Market Considered Lucrative within Europe?

In Germany, biodefense products and services are manufactured and sold to protect against biological threats such as infectious diseases and bioterrorism. It consists of a wide range of products and services, including vaccinations, diagnostic tests, protective equipment, and decontamination systems.

Germany is considered a leading player in the global biodefense market. This is because it has a strong presence of multinational corporations and government institutions involved in research and development, as well as the production and distribution of biodefense products. The government of Germany has also made significant investments in the biodefense sector, which has helped to spur growth and innovation in the market.

Overall, the biodefense market in Germany is expected to continue growing in the coming years. This is driven by factors such as increasing concerns about global pandemics, bioterrorism, and the growing threat of antimicrobial resistance.

What Makes China Biodefense Market Highly Attractive?

During the forecast period, China is expected to expand at the high rate of 8.8% due to surges in Research and development. Growing awareness of biodefense, as well as the threat of harmful biological materials that engender emergencies, can drive growth in the biodefense market.

A combination of this and a sophisticated healthcare infrastructure contributes to China's market position. In addition, China is vigorously expanding its research and development capabilities to meet future biological threats. After the United States, China spends the second highest percentage of its GDP on research and development. These factors are expected to boost China's biodefense industry.

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Start-up Ecosystem

The biodefense market is home to several startups around the world. These startups are focused on developing innovative solutions to protect against biological threats, including infectious diseases and bioterrorism.

Some examples of Startups Operating in the Biodefense Market include:

  • BioMimetix JV, LLC: a company based in Germany develops biometric solutions for identifying and tracking infectious diseases.
  • BioDetectors: the United Kingdom-based startup that develops rapid diagnostic tests for the detection of biological threats.
  • PathAI: a company that uses artificial intelligence to improve the accuracy of disease diagnosis.
  • Tener Vaccines: Germany-based startup that focuses on the development of vaccines for the prevention of infectious diseases.
  • Takeda Pharmaceuticals: Japan-based pharmaceutical company that develops and sells vaccines and treatments for infectious diseases.
  • Biomatrica: the United States-based company that provides solutions for the preservation of biological samples for research and diagnostic purposes.

These startups are working on developing and commercializing cutting-edge technologies and products to address the challenges posed by biological threats. They play an influential role in driving innovation and growth in the biodefense market.

Competitive Landscape: Key Players Operating in the Market

In emerging and economically favorable regions, many of these players are notably collaborating with governments to gain bulk orders and boost sales. Many companies are partnering with each other to develop drugs so that they can introduce their products fast.

Key players operating in the Market:

  • XOMA Corporation
  • Altimmune Inc.
  • Emergent Biosolutions Inc.
  • Dynavax Technologies Corporation
  • SIGA Technologies
  • Elusys Therapeutics Inc
  • Ichor Medical Systems
  • Dynport Vaccine Company
  • Cleveland Biolabs
  • Bavarian Nordic
  • Ology Bioservices
  • Alnylam Pharmaceuticals Inc.

Recent Developments:

Key players are focusing on novel and innovative approaches for the development of new Biodefenses. The strategy of expansion, new product launches, and approvals, by key manufacturers, are crucial strategies for further strengthening the presence of market players and allowing them to stay ahead of the competition.

  • Appili Therapeutics Inc. announced funding of over USD 10 million in February 2022 to advance its biodefense vaccine candidate, ATI-1701, to prevent infection with Francisella tularensis. This funding is expected to boost the company's presence and boost growth in the biodefense market.
  • It was reported that Emergent BioSolutions Inc. (NYSE: EBS) has received approval for the Biologics License Application (BLA) for AV7909 (Anthrax Vaccine Adsorbed, Adjuvanted) from the United States Food and Drug Administration (FDA).
  • It was announced in May 2022 that Emergent BioSolutions Inc. had signed a definitive agreement with Chimerix, Inc. to acquire Chimerix's exclusive worldwide rights to TEMBEXA (brincidofovir), the first antiviral approved by the United States Food and Drug Administration (FDA) to treat smallpox in all age groups.
  • The privately held company Ichor Medical Systems, Inc., announced in March 2019 that it collaborated with AstraZeneca for the development and clinical assessment of plasmid DNA constructs (recombinant monoclonal antibodies). Aside from upfront and annual payments, Ichor may also be paid development milestones under the terms of the agreement.
  • CEPI (the Coalition for Epidemic Preparedness Innovations) entered into a collaboration with Profectus BioSciences, Inc. and Emergent BioSolutions Inc., in August 2018, to manufacture a vaccine against the Lassa virus. Through this collaboration, companies were able to expand their product portfolio.

Scope of Report

Attribute Details
Forecast Period 2023 to 2033
Historical Data Available for 2017 to 2022
Market Analysis USD million for Value and MT for Volume
Key Regions Covered North America; Latin America; Europe; The Middle East and Africa; East Asia
Key Countries Covered United States, Canada, Brazil, Mexico, Chile, Peru, Germany, United Kingdom, Spain, Italy, France, Russia, Poland, China, India, Japan, Australia, New Zealand, GCC Countries, North Africa, South Africa, and Türkiye
Key Segments Covered ProductProduct, Region
Key Companies Profiled XOMA Corporation; Altimmune Inc.; Emergent Biosolutions Inc.; Dynavax Technologies Corporation; SIGA Technologies; Elusys Therapeutics Inc; Ichor Medical Systems; Dynport Vaccine Company; Cleveland Biolabs; Bavarian Nordic; Ology Bioservices; Alnylam Pharmaceuticals Inc.
Report Coverage Market Forecast, Company Share Analysis, Competition Intelligence, DROT Analysis, Market Dynamics and Challenges, and Strategic Growth Initiatives
Customization & Pricing Available upon Request
Table of Content
  • 1. Executive Summary
  • 2. Market Overview
  • 3. Market Background
  • 4. Global Market Analysis 2018 to 2022 and Forecast, 2023 to 2033
  • 5. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Type
    • 5.1. Anthrax Biodefense
    • 5.2. Botulism Biodefense
    • 5.3. Smallpox Biodefense
    • 5.4. Cholera Biodefense
    • 5.5. Influenza Biodefense
  • 6. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By End-User
    • 6.1. Hospitals and Clinics
    • 6.2. Ambulatory Care Centres
  • 7. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Region
    • 7.1. North America
    • 7.2. Latin America
    • 7.3. Europe
    • 7.4. South Asia
    • 7.5. East Asia
    • 7.6. Oceania
    • 7.7. MEA
  • 8. North America Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
  • 9. Latin America Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
  • 10. Europe Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
  • 11. South Asia Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
  • 12. East Asia Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
  • 13. Oceania Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
  • 14. MEA Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
  • 15. Key Countries Market Analysis
  • 16. Market Structure Analysis
  • 17. Competition Analysis
    • 17.1. XOMA Corporation
    • 17.2. Altimmune Inc.
    • 17.3. Emergent Biosolutions Inc.
    • 17.4. Dynavax Technologies Corporation
    • 17.5. SIGA Technologies
    • 17.6. Elusys Therapeutics Inc.
    • 17.7. Ichor Medical Systems
    • 17.8. Dynport Vaccine Company
    • 17.9. Cleveland Biolabs
    • 17.10. Bavarian Nordic
    • 17.11. Ology Bioservices
    • 17.12. Alnylam Pharmaceuticals Inc.
  • 18. Assumptions & Acronyms Used
  • 19. Research Methodology

Biodefense Market Segmentation by Category

By Product:

  • Anthrax
  • Smallpox
  • Botulism
  • Radiation/Nuclear

By Region Outlook:

  • North America
  • Latin America
  • Europe
  • The Middle East and Africa
  • East Asia

Frequently Asked Questions

What is the Current Valuation of the Biodefense Market?

The valuation of the biodefense market reaches a notable sum of USD 16.31 billion in 2023.

What is the Estimated Biodefense Market Size Envisioned by 2033?

The biodefense market is estimated to achieve a valuation of USD 32.99 billion by 2033.

What CAGR is Foreseen for the Biodefense Market in the Upcoming Decade?

The biodefense market is poised to witness a 7.3% CAGR through 2033.

Which is the Top Trend in the Biodefense Market?

Advanced detection technologies stand out as the top trend in the biodefense market.

Which is the Key Segment in the Biodefense Market by Product Type?

The anthrax segment is positioned to sustain its preference in the market through 2033, holding a 28.1% share.

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