Atypical Hemolytic Uremic Syndrome (aHUS) Treatment Market Snapshot (2023 to 2033)

The global atypical hemolytic uremic syndrome (ahus) treatment market is expected to garner a market value of USD 1431 Million in 2023 and is expected to accumulate a market value of USD 2308.84 Million by registering a CAGR of 4.9% in the forecast period 2023 to 2033. Growth of the atypical hemolytic uremic syndrome (ahus) treatment market can be attributed to increase in research and development activities to offer various treatments to treat the ailment.

The market for atypical hemolytic uremic syndrome (ahus) treatment registered a CAGR of 3.4% in the historical period 2018 to 2022.

Atypical Hemolytic Uremic Syndrome (aHUS) is a rare, life-threatening disorder that causes abnormal blood clotting in small blood vessels, leading to damage to vital organs such as the kidneys, brain, and heart. The goal of treatment for aHUS is to control the disease and prevent further damage to organs. Treatment of atypical hemolytic uremic syndrome (ahus) treatment include plasma exchange, plasma infusion, immunotherapy, complement inhibitors and supportive care.

Report Attribute Details
Expected Market Value (2023) USD 1431 Million
Anticipated Forecast Value (2033) USD 2308.84 Million
Projected Growth Rate (2023 to 2033) 4.9% CAGR

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2018 to 2022 Atypical Hemolytic Uremic Syndrome (aHUS) Treatment Market Demand Analysis vs. Forecast 2023 to 2033

According to market research and competitive intelligence provider Future Market Insights- the market for Atypical hemolytic uremic syndrome (ahus) treatment reflected a value of 3.4% during the historical period, 2018 to 2022.

Increasing prevalence of aHUS, growing awareness and diagnosis of the disease, and the development of new and effective treatments are creating lucrative opportunities for the growth of the market. In terms of treatment type, complement inhibitors have emerged as a popular treatment option for aHUS. Several drugs, including eculizumab (Soliris), ravulizumab (Ultomiris), and pegcetacoplan (Empaveli) have been approved by regulatory agencies for the treatment of aHUS, and additional drugs are in various stages of development.

Geographically, North America and Europe are the leading regions for aHUS treatment due to the high prevalence of the disease in these regions and the availability of advanced healthcare facilities. However, the Asia Pacific region is expected to grow at a significant pace in the coming years due to increasing awareness and diagnosis of the disease and the development of new treatments.

Thus, the market for Atypical hemolytic uremic syndrome (ahus) treatment is expected to register a CAGR of 4.9% in the forecast period 2023 to 2033.

Which are Some Prominent Drivers of Atypical Hemolytic Uremic Syndrome (aHUS) Treatment Market?

Presence of diagnostic tests along with innovation of new therapies spurring market growth

Although aHUS is a rare disease, the incidence of the disease is increasing, leading to a higher demand for effective treatments. With the availability of more sensitive diagnostic tests, more cases of aHUS are being identified, leading to a higher demand for treatment.

In recent years, new therapies have been developed that specifically target the underlying mechanisms of aHUS, such as complement dysregulation. These therapies offer new treatment options for patients with aHUS. Governments in many countries are taking steps to promote research into rare diseases, including aHUS. This support is helping to drive the development of new therapies and expand access to existing treatments. As more is understood about aHUS, there is growing awareness of the disease among patients, caregivers, and healthcare professionals. This increased awareness is leading to earlier diagnosis and treatment of aHUS, which is helping to improve patient outcomes.

Availability of treatments driving growth of atypical hemolytic uremic syndrome (ahus) treatment market Top of Form

Plasma exchange: Plasma exchange involves removing the patient's plasma and replacing it with donor plasma. This helps to remove the harmful antibodies that are attacking the patient's blood cells and causing damage.

Plasma infusion: Plasma infusion involves giving the patient extra plasma, which contains the proteins that help control blood clotting. This can help to restore normal clotting and prevent further damage.

Immunotherapy: Immunotherapy involves giving medications that suppress the immune system and prevent it from attacking the patient's own cells. These medications may include steroids, monoclonal antibodies, or other immunosuppressive drugs.

Complement inhibitors: Complement inhibitors are medications that block the activity of the complement system, which is a part of the immune system that can cause damage in aHUS. These medications may include eculizumab, ravulizumab, or other complement inhibitors.

Supportive care: Supportive care may include treatments to manage symptoms and complications of aHUS, such as dialysis for kidney failure, blood transfusions to replace damaged blood cells, and medications to control high blood pressure.

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What are the Challenges Faced by the Atypical Hemolytic Uremic Syndrome (aHUS) Treatment Market?

Limited availability of treatments affecting market growth for aHUS

The cost of aHUS treatment can be very high, which can limit access to care for some patients. The high cost is due to the complexity of the disease, the need for specialized treatment, and the relatively low patient population. While there are several treatments available for aHUS, including plasma exchange, immunosuppressive therapy, and complement inhibitors, there are limited options for some patients. This can be due to the limited availability of certain treatments or the lack of response to existing therapies.

A lack of awareness and expertise among healthcare professionals can lead to delayed diagnosis and treatment of aHUS. This can result in poorer outcomes for patients. aHUS is a rare disease, which means that the patient population is relatively small. This can make it difficult to conduct clinical trials and develop new treatments. Like any treatment, aHUS therapies can have adverse effects, and some patients may not tolerate the available treatments. All these factors are hampering the growth of the market.

Region-Wise Insights

Research and Development Shaping Landscape of Treatment for Atypical Hemolytic Uremic Syndrome in North America?

Development of new therapies leading to market growth in North America

The prevalence of aHUS is relatively high in North America compared to other regions, which increases the demand for aHUS treatment. North America has a strong tradition of innovation and technological advancements in the healthcare sector, which has led to the development of new treatments and therapies for aHUS. In addition, the region has a well-established healthcare industry, with advanced healthcare facilities and highly skilled healthcare professionals, which enhances the quality of aHUS treatment.

Governments in North America are taking steps to promote research into rare diseases, including aHUS, and this support is driving the development of new therapies and improving access to existing treatments. There is growing awareness of aHUS among patients, caregivers, and healthcare professionals in North America, leading to earlier diagnosis and treatment of the disease. Thus, North America is expected to possess 44% market share for atypical hemolytic uremic syndrome (ahus) treatment market in 2023.

Technological Advancements in the Healthcare Sector Boosting Atypical Hemolytic Uremic Syndrome (aHUS) Treatment Market Growth in Europe?

Government initiatives along with growing prevalence bolstering market growth in Europe

The Europe Atypical Hemolytic Uremic Syndrome (aHUS) Treatment Market is a significant segment of the global aHUS treatment market, driven by a high prevalence of aHUS, technological advancements, government initiatives and support is propelling the growth of the market.

Moreover, growing awareness of aHUS among patients, caregivers, and healthcare professionals in Europe, leading to earlier diagnosis and treatment of the disease. Furthermore, several collaborations and partnerships among healthcare companies, academic institutions, and research organizations are driving the development of new treatments for aHUS. Thus, Europe is expected to possess 38% market share for atypical hemolytic uremic syndrome (ahus) treatment market in 2023.

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Category-Wise Insights

Availability of Complement Inhibitors Making Hospital Pharmacies Popular for aHUS Treatment?

Better patient outcomes and presence of trained pharmacists driving growth of hospital pharmacies

Hospital pharmacies are equipped to store and dispense specialized medications, such as complement inhibitors, which are commonly used to treat aHUS. Moreover, they often work in collaboration with healthcare providers to ensure that patients receive the correct medication and dose. This helps to optimize patient outcomes and reduce the risk of adverse events.

Hospital pharmacists are highly trained and have a deep understanding of the drugs they dispense, including their mechanisms of action, side effects, and drug interactions. This expertise is particularly important for aHUS patients, as the disease requires specialized treatment. In addition to these factors, the growing prevalence of aHUS and the increasing use of complement inhibitors for treatment are also contributing to the growing prominence of hospital pharmacies in aHUS treatment. Thus, hospital pharmacies are expected to possess 45% market share for atypical hemolytic uremic syndrome (ahus) treatment market in 2023.

Market Competition

Key players in the atypical hemolytic uremic syndrome (ahus) treatment market are Alexion Pharmaceuticals, Omeros Corporation, Novartis Pharmaceuticals, Hoffmann-La Roche, Chugai Pharmaceutical, Tasly Biopharmaceuticals, Prestige BioPharma, Abbott Medtronic, Teva Pharmaceuticals Ltd., Zydus Pharmaceuticals, Inc.

  • Roche's lead drug for aHUS named satralizumab, a monoclonal antibody targets the interleukin-6 (IL-6) receptor. Satralizumab is not a direct complement inhibitor, but rather works by blocking the IL-6 pathway, which is a key pathway in the inflammation process that can contribute to complement activation in patients with aHUS.
  • Tasly's lead drug for aHUS called TJ301, a recombinant humanized anti-C5 monoclonal antibody targets the complement system. TJ301 binds to complement protein C5 and prevents the formation of the membrane attack complex, which can cause damage to red blood cells, platelets, and other cells in the body.

Report Scope

Report Attribute Details
Market Value in 2023 USD 1431 Million
Market Value in 2033 USD 2308.84 Million
Growth Rate CAGR of 4.9% from 2023 to 2033
Base Year for Estimation 2022
Historical Data 2018 to 2022
Forecast Period 2023 to 2033
Quantitative Units Revenue in USD Million and CAGR from 2023-2033
Report Coverage Revenue Forecast, Volume Forecast, Company Ranking, Competitive Landscape, Growth Factors, Trends and Pricing Analysis
Segments Covered Product Type, Molecule Type, Polymer, Route of Administration, Region
Regions Covered North America; Latin America; Europe; South Asia; East Asia; Oceania; MEA
Key Countries Profiled USA, Canada, Brazil, Mexico, Rest of Latin America, Germany, United Kingdom, France, Spain, Italy, Rest of Europe, India, Malaysia, Singapore, Thailand, Rest of South Asia, China, Japan, South Korea, Austria, New Zealand, GCC countries, South Africa, Israel, Rest of MEA
Key Companies Profiled Alexion Pharmaceuticals; Omeros Corporation; Novartis Pharmaceuticals; Hoffmann-La Roche; Chugai Pharmaceutical; Tasly Biopharmaceuticals; Prestige BioPharma; Abbott Medtronic; Teva Pharmaceuticals Ltd.; Zydus Pharmaceuticals, Inc.
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Table of Content
  • 1. Executive Summary | Atypical Hemolytic Uremic Syndrome (aHUS) Treatment Market
  • 2. Market Overview
  • 3. Market Background
  • 4. Global Market Analysis 2018 to 2022 and Forecast, 2023 to 2033
  • 5. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Product Type
    • 5.1. Mono
    • 5.2. Combination
    • 5.3. Mono/Combination
  • 6. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Molecule Type
    • 6.1. Monoclonal Antibody
    • 6.2. Peptides
    • 6.3. Polymer
    • 6.4. Small molecule
    • 6.5. Gene therapy
  • 7. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Route of Administration
    • 7.1. Oral
    • 7.2. Parenteral
    • 7.3. Intravenous
    • 7.4. Subcutaneous
    • 7.5. Topical
  • 8. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Distribution Channel
    • 8.1. Hospital Pharmacy
    • 8.2. Retail Pharmacy
    • 8.3. Online Pharmacy
  • 9. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Region
    • 9.1. North America
    • 9.2. Latin America
    • 9.3. Europe
    • 9.4. South Asia
    • 9.5. East Asia
    • 9.6. Oceania
    • 9.7. MEA
  • 10. North America Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
  • 11. Latin America Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
  • 12. Europe Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
  • 13. South Asia Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
  • 14. East Asia Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
  • 15. Oceania Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
  • 16. MEA Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
  • 17. Key Countries Market Analysis
  • 18. Market Structure Analysis
  • 19. Competition Analysis
    • 19.1. Alexion Pharmaceuticals
    • 19.2. Omeros Corporation
    • 19.3. Novartis Pharmaceuticals
    • 19.4. Hoffmann-La Roche
    • 19.5. Chugai Pharmaceutical
    • 19.6. Tasly Biopharmaceuticals
    • 19.7. Prestige BioPharma
    • 19.8. Abbott Medtronic
    • 19.9. Teva Pharmaceuticals Ltd.
    • 19.10. Zydus Pharmaceuticals, Inc.
  • 20. Assumptions & Acronyms Used
  • 21. Research Methodology

Key Segments Profiled in the Atypical Hemolytic Uremic Syndrome (aHUS) Treatment Industry Survey

Product Type:

  • Mono
  • Combination
  • Mono/Combination

Molecule Type:

  • Monoclonal Antibody
  • Peptides

Polymer:

  • Small molecule
  • Gene therapy

Route of Administration:

  • Oral
  • Parenteral
  • Intravenous
  • Subcutaneous
  • Topical

Distribution Channel:

  • Hospital Pharmacy
  • Retail Pharmacy
  • Online Pharmacy

Region:

  • North America
  • Latin America
  • Europe
  • South Asia
  • East Asia
  • Oceania
  • MEA

Frequently Asked Questions

What is Expected Market Share of North America in 2023?

In 2023, North America is anticipated to hold 44% of the market for aHUS treatments.

How Big will the Market in Asia Pacific by 2033?

The Asia Pacific market is anticipated to reach USD 2,308.84 million by 2033.

Which Country is Set to Register Exponential Growth in the Market?

The aHUS therapy market in China is predicted to increase rapidly.

What Drives Sales of Atypical Hemolytic Uremic Syndrome (aHUS) Treatment Market?

The rising incidence of the illness, greater public knowledge, and the availability of efficient treatment alternatives.

What Key Trends are Driving the Atypical Hemolytic Uremic Syndrome (aHUS) Treatment Market?

The accessibility of efficient therapies and the rise in demand for personalized care.

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