Antihistamine Market

Antihistamine Market Outlook for 2023 to 2033

The global antihistamine product market was valued at USD 263.9 billion in 2022. The market is expected to expand at a CAGR of 8.6% and reach a valuation of ~USD 647.7 billion by 2033.

Data Points	Market Insights
Antihistamine Market Value, 2022	USD 263.9 billion
Antihistamine Market Value, 2023	USD 284.2 billion
Antihistamine Market Value, 2033	USD 647.7 billion
CAGR (2023 to 2033)	8.6%
Market Share of Top 5 Countries	50.5%
Key Market Players	GlaxoSmithKline PLC., Sanofi Consumer Healthcare, Himalaya Wellness Company, Sun Pharmaceutical Industries, Inc., Bayer AG, Novartis AG, Cadila Pharmaceuticals, Bausch Health Companies Inc., Alcon Vision LLC., Merck & Co., Dr. Reddy’s Laboratories, Ltd., Viatris Inc., Somerset Pharma, LLC, F. Hoffmann- La Roche Ltd., Akorn Operating Company LLC, Teva Pharmaceutical Industries Ltd., Speer laboratories, Glenmark Pharmaceuticals Limited, TerSera Therapeutics LLC, Pfizer Inc., Morepen Laboratories Limited, Johnson & Johnson Sevices Inc., Pharmaceutical Specialties Inc., Proctor & Gamble

The antihistamine market has observed significant growth over the last decade. The increasing prevalence of allergies and allergic reactions across the globe has expanded the growth of the antihistamine market. Antihistamine drugs are used to treat a variety of allergies and allergic reactions, as it is an anti-allergic medication.

The body acts on certain histamine receptors and releases histamine throughout an allergic reaction. Antihistamine can also treat pruritus-related conditions such as atopic dermatitis, insect bites, and other conditions. Moreover, H-1 and H-2 types of antihistamine are used to treat other conditions such as insomnia, motion sickness, anxiety and heartburn, gastric ulcers, and others, respectively.

Historical Performance of Antihistamine Market from 2017 to 2022 Vs Market Outlook for 2023 to 2033

The market value for antihistamines was approximately 1.3% of the overall global allergy treatment market worth ~USD 19,070.0 billion in 2022.

Historical Antihistamine Market Value (2022)	USD 263.9 billion
Historical CAGR (2017 to 2022)	5.9%

The sale of antihistamines expanded at a CAGR of 5.9% from 2017 to 2022. The demand for antihistamine products will keep up strong in the years ahead.

The preference for antihistamine drugs for treatment procedures is growing as the accessibility of these drugs is highly convenient through retail pharmacies, hospital pharmacies, and online pharmacies. This is one of the factors influencing the production growth of antihistamines. Numerous manufacturers are utilizing different antihistamine dosage forms to enhance their market share.

Allergic reactions caused on the skin are distinguished by red, peeling, dry, swollen surface, itch, and rash. The most common triggering factor for allergies is the overreaction of histamine in the body; this is when antihistamines come into action. Antihistamines assist in reducing inflammation, which usually alleviates the pain.

Apart from that, skin conditions such as allergic rhinitis can occur due to prolonged and repeated exposure to dust mites, molds, or pet dander. It can further lead to symptoms such as nasal congestion and irritation in the nose, throat, and eyes, increasing the growth of the antihistamine market.

Medical professionals prescribe antihistamines to relieve symptoms of insomnia as well. Due to the current environment and lifestyle, such as unstable working shifts, smoking, varied sleeping patterns and others, the antihistamine market has witnessed growth in conditions such as insomnia, which is the most common issue among the general population today.

According to an article published by the American Journal of Managed Care in 2020, around 30% to 40% of the USA adult population develop symptoms of insomnia per year. The inability to fall asleep or stay asleep can have a major influence on productivity and mood. It can be a symptom or a cause of other underlying medical disorders.

Easily available over-the-counter drugs such as diphenhydramine can assist in sleeping aids. An antihistamine is not a first-line treatment for insomnia but first-generation antihistamine blocks H-1 histamine receptors, which can cause sedation and make the patients drowsy. These factors can be favorable for the antihistamine market.

Thus, owing to the aforementioned factors, the global market is expected to grow at a CAGR of 8.6% during the forecast period from 2023 to 2033.

Key Opportunities in the Antihistamine Market

The growth will be driven by the increasing concerns regarding the prevalence of allergic reactions and other conditions such as urticaria and anxiety across the globe. Further, the market opportunistic outlook is owing to the increasing investments in research and development, due to which drug approvals are rising and new products concerning antihistamine drugs are being launched, which is expanding the market.

For instance, in May 2022, Glenmark Pharmaceuticals launched a nasal spray in India named Ryaltris-AZ. Ryaltris-AZ was introduced as the first-line treatment for allergic rhinitis with a mixture of intranasal antihistamines and corticosteroids.

Moreover, a number of manufacturers are expanding their line of medications by providing antihistamine drugs in multiple routes of administration, increasing the range of antihistamine-related products in the market. Hence, in the forthcoming years, the antihistamine market is expected to dispense lucrative growth opportunities.

Restraints in the Antihistamine Market

Sometimes, due to a lack of awareness among the rural population in some developing countries, it becomes difficult to cope with allergies and other conditions. It is because of negligence and inability to seek medical help. This is a crucial factor hampering the growth of the market.

Antihistamine blocks the process of histamine, but at times, there are a few side effects that can be caused due to antihistamines. These side effects include drowsiness, dry mouth, dry eyes, sore throat, and others. This factor acts as a barrier and affects the growth of the market in a negative manner.

Country-wise Insights

Countries	CAGR (2023 to 2033)
United States	8.9%
China	8.6%
United Kingdom	8.0%
Germany	8.2%
India	7.8%

Prevalence of Allergies in the United States Drive Sales of Antihistamines

The United States dominates the North American region, with a total market share of about 85.4% in 2022. The market is expected to grow at a CAGR of 8.9% through 2033.

According to the Centers for Disease Control and Prevention, more than 60 million people per year in the United States suffer from hay fever. It was also reported that seven out of ten patients in 2020 were suffering from hay fever along with allergic conjunctivitis that causes red, watery, and itchy eyes. The prevalence of allergies in the USA is driving the market. There are numerous antihistamine medications that provide relief from such inflammation symptoms. These are the prime drivers for the market within the country.

Rising Demand For Antihistamines in China Due to Allergies Among Children

China dominates the East Asian region with a total market share of about 51.2%. It is estimated to grow at a CAGR of 8.6% throughout the forecast period.

Allergic rhinitis is becoming a major concern in terms of health and economy in China. Children in China are more prone to such disorders due to allergens like house dust mites. As the prevalence of allergies and allergic reactions is rising, the demand for antihistamines is increasing, boosting market growth.

Increasing Prevalence of Allergic Conjunctivitis in India

India is set to exhibit a CAGR growth rate of nearly 7.8% during the forecast period. Due to the increasing prevalence of allergic conjunctivitis in the general population of India, the consumption of the antihistamines for the treatment is increasing, contributing to the growth of the Indian market.

Allergy-based disorders in India are becoming a matter of concern due to factors like the illiteracy among the rural population and paucity of allergy specialists.

Category-wise Insights

H-1 Blockers Dominate the Market by Product

Top Product	H-1 blockers
CAGR (2023 to 2033)	8.9%

H-1 blockers are expected to present high growth at a CAGR of 8.9% over the forecast period, with a market share of about 55.9%. H-1 antihistamines can alleviate the pain caused by allergic conjunctivitis, skin rashes and hypersensitivity toward certain drugs.

Sales of Antihistamines through Over-the-Counter

Top Type	Over-the-counter
CAGR (2023 to 2033)	9.0%

Over-the-counter antihistamines are dominating the market with a share of 51.3% in 2022. This segment is expected to present high growth at a CAGR of 9.0% by the end of the forecast period. Antihistamine drugs are easily available through over-the-counter means. Therefore, this segment is considered to be dominant in the type category.

Tablets are Highly Preferred Dosage Form

Top Dosage	Tablets
CAGR (2023 to 2033)	9.7%

Tablets hold a market share of 35.0% in 2022 and are expected to display gradual growth over the forecast period, with a CAGR of 9.7%. Tablets are one the most convenient and economical dosage forms of antihistamines.

Oral Route of Drug Administration Dominates the Market

Top Route of Administration	Oral
CAGR (2023 to 2033)	8.0%

The oral route of administration is dominating the market and is expected to grow at a CAGR of 8.0% over the forecast period, with a market share of about 48.7% in the global market in 2031. Oral medications are quite advantageous as compared to parental and topical medications. These advantages include patient preference, the convenience of drug administration, and cost-effectiveness.

Hospital Pharmacies Facilitate Higher Sales of Antihistamine Drugs

Top Distribution Channel	Hospital pharmacies
CAGR (2023 to 2033)	9.1%

Hospital pharmacies hold a prominent market share value of 42.9% during the year 2022 with a CAGR of 9.1%. The increasing number of hospital pharmacies is a factor contributing to the prominent share of hospital pharmacies in the distribution channel category.

Competitive Landscape and Recent Developments

The market is a highly fragmented market with numerous key players. To meet consumer demands and strengthen their presence worldwide, these companies are executing a new range of products and regulatory approvals. Few of the key developmental strategies of market players are given below:

• In June 2020, Cadila Pharmaceuticals announced the launch of Bilastin syrup and tablets in India. Bilastin is an anti-allergic drug used for the treatment of allergic rhinitis.
• In December 2022, Morepen Laboratories Limited announced the USA FDA approval of fexofenadine hydrochloride. It is an anti-allergy drug used for the treatment of symptoms due to allergies and hay fever. It was launched under the brand ‘Allerga’

Report Scope as per Market Industry Analysis

Attribute	Details
Forecast Period	2023 to 2033
Historical Data Available for	2017 to 2022
Market Analysis	USD billion for Value
Key Regions Covered	North America; Latin America; Europe; South Asia; East Asia; Oceania; and Middle East & Africa
Key Countries Covered	USA, Canada, Brazil, Mexico, Argentina, Germany, France, Italy, UK, Spain, Russia BENELUX, Nordic Countries, India, Thailand, Indonesia, Malaysia, China, Japan, South Korea, Australia, New Zealand, GCC Countries, Turkey, Northern Africa, and South Africa
Key Market Segments Covered	Product, Type, Dosage Forms, Route of Administration, Indication, Distribution Channel and Region
Key Companies Profiled	GlaxoSmithKline PLC.; Sanofi Consumer Healthcare; Himalaya Wellness Company; Sun Pharmaceutical Industries, Inc.; Bayer AG; Novartis AG; Cadila Pharmaceuticals; Bausch Health Companies Inc.; Alcon Vision LLC.; Merck & Co.; Dr. Reddy’s Laboratories, Ltd.; Viatris Inc.; Somerset Pharma, LLC; F. Hoffmann- La Roche Ltd.; Akorn Operating Company LLC; Teva Pharmaceutical Industries Ltd.; Speer laboratories; Glenmark Pharmaceuticals Limited; TerSera Therapeutics LLC; Pfizer Inc.; Morepen Laboratories Limited; Johnson & Johnson Services Inc.; Pharmaceutical Specialties Inc.; Proctor & Gamble
Pricing	Available upon Request

Key Market Segments Covered in Market Industry Research

By Product:

• H-1 Blockers
• H-2 Blockers

By Type:

• Prescription-based
• Over-the-counter

By Dosage Forms:

• Tablets
• Capsules
• Liquids
• Other

By Route of Administration:

• Oral
• Parenteral
• Topical

By Indication:

• Allergies
• Urticaria
• Dermatitis
• Other

By Distribution Channel:

• Hospital Pharmacies
• Retail Pharmacies
• Drug stores
• Online Pharmacies

By Region:

• North America
• Latin America
• Europe
• South Asia
• East Asia
• Oceania
• Middle East and Africa (MEA)

Frequently Asked Questions

How Much was the Value of the Antihistamine Market in 2022?

The global antihistamine market is worth USD 263.9 billion in 2022.

What is the Sales Forecast for Antihistamines through 2033?

The antihistamine market is expected to reach USD 647.7 billion by 2033, growing at a CAGR of 8.6% over the forecast period.

What are the Trends Driving the Global Antihistamine Market?

Increased efficacy of antihistamines with respect to relieving symptoms and allergic reactions across the globe.

Which Region has the Prominent Share in the Global Antihistamine Market?

North America dominated the global antihistamine market accounting for a prominent market share of 34.6%.

How is the Market Expected to Grow in India?

The market in India is likely to grow with a CAGR of 7.8% over the forecast period.

Which are the Top Five Countries Driving the Demand for Antihistamines?

The United States, China, the United Kingdom, Germany, and India are the top five countries, which are expected to drive demand for antihistamines.