Amyotrophic Lateral Sclerosis Market Snapshot (2023 to 2033)

The global Amyotrophic Lateral Sclerosis market is expected to garner a market value of US$ 743.90 Million in 2023 and is expected to accumulate a market value of US$ 1332.22 Million by registering a CAGR of 6% in the forecast period 2023 to 2033. The growth of the Amyotrophic Lateral Sclerosis market can be attributed to the rising geriatric population, growing awareness about ALS, and increasing incidence rate. The market for Amyotrophic Lateral Sclerosis registered a CAGR of 4% in the historical period 2017 to 2022.

Supplemental approvals for existing treatment options are likely to bolster market growth in future years. In addition to that, many renowned companies are aiming to submit their applications for approval for new drug therapies, which is another crucial factor that is estimated to aid the growth.

Report Attribute Details
Expected Market Value (2023) US$ 743.90 Million
Anticipated Forecast Value (2033) US$ 1332.22 Million
Projected Growth Rate (2023 to 2033) 6% CAGR

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2017 to 2022 Amyotrophic Lateral Sclerosis Market Demand Analysis vs. Forecast 2023 to 2033

According to market research and competitive intelligence provider Future Market Insights- the market for Amyotrophic Lateral Sclerosis reflected a value of 4% during the historical period, 2017 to 2022. National lockdown, government controls, and a spike in infection rates across countries all had a major financial impact on client engagement.

Amyotrophic lateral sclerosis, a progressive neurodegenerative disorder, damages nerve cells in the central nervous system responsible for controlling voluntary muscles. As per studies, around half of the people suffering from ALS may lose the ability to swallow, breathe, speak, walk, and use their hands. Thus, the market for Amyotrophic Lateral Sclerosis is expected to register a CAGR of 6% in the forecast period 2023 to 2033.

Which are Some Prominent Drivers of Amyotrophic Lateral Sclerosis Market?

Increasing incidence of cancer to push the market growth

The increasing prevalence of amyotrophic lateral sclerosis disease is one of the biggest drivers of the market. According to the National Institute of Neurological Disorders and Stroke (NINDS), following gradual paralysis, patients with ALS often die from respiratory failure within 3-5 years. It also states that between the two types of ALS, the sporadic type is the most common form, accounting for 90- 95% of all cases in the USA while the familial type accounts for the rest.

In addition to this, an inclination of the population towards a stationary lifestyle and an increasing geriatric population has increased the demand for targeted and indicated treatment options, which are driving the global amyotrophic lateral sclerosis market.

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What are the Challenges Faced by the Amyotrophic Lateral Sclerosis Market?

Expensive Cost of Treatment to restrict Market Growth

The expensive treatment of Amyotrophic lateral sclerosis, less awareness of amyotrophic lateral sclerosis disease, and insubstantial treatment options are hampering the market growth.

Region-Wise Insights

How is the Market for Amyotrophic Lateral Sclerosis Turning Out in the Asia Pacific Region?

Increased revenue generation propelling the growth of Amyotrophic Lateral Sclerosis in Asia Pacific

The Asia Pacific is expected to exhibit the fastest growth rate of all regions over the forecast period, with a CAGR of 5% during the forecast period.

The industry is witnessing increasing revenue generation in this region, especially in India and China. Major factors propelling the market growth in this region include growing Research and Development investment in the healthcare sector, plenty of unexplored opportunities, and promising initiatives by the manufacturers as well as the governments.

What are the Factors Boosting the Market for Amyotrophic Lateral Sclerosis in North America?

High Concentration of Key Players shaping the landscape for Amyotrophic Lateral Sclerosis in North America

North America is anticipated to acquire a market share of about 20% in the forecast period. This growth is attributable to the availability of recently developed immunosuppressants and the presence of a favorable reimbursement scenario across the USA.

It is estimated that the high healthcare expenditure along with the huge demand for ALS drugs, and established healthcare infrastructure are the factors driving the market. According to the data published in the Centers for Disease Control and Prevention (CDC) Morbidity and Mortality Weekly Report, in 2015 around 16,583 cases of amyotrophic lateral sclerosis were identified in the USA

Besides, the presence of a large number of significant pharmaceutical companies in the USA is set to bode well for the North American market. Thus, given the aforementioned factors, the market is expected to grow significantly over the forecast period in North America.

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Category-Wise Insights

Based on Treatment, Which Segment is Pushing the Market Growth?

The superior efficiency of Stem cell therapy bolsters the growth

On the basis of treatment, the segment has been divided into medications, stem cell therapies, and others. Stem cell therapy is expected to show the highest CAGR owing to the increasing demand for new approaches and advanced treatment options. In addition to this, several initiatives have been taken by the government authoritative bodies and the Collaborative ALS Drug Discovery Initiative (CADDI) to fast-track the development of novel drugs and treatments.

By Distribution Channels, Which Segment Dominates the Market?

Hospital pharmacies to drive market growth

The distribution channel segment has been divided into hospital pharmacies, retail pharmacies, and others. According to the FMI analysis, Hospital pharmacies account for the largest market share. The requirement for several hospital stays and visits during ALS treatment facilitates the growth of this segment.

Start-up in the Amyotrophic Lateral Sclerosis Market

Key start-up players in the Amyotrophic Lateral Sclerosis market are-

  • Since its founding in Tel Aviv in 2017, neurodegenerative disease start-up NeuroSense Therapeutics has been eyeing the USA market. Now, the company (Nasdaq: NRSN) is using its local headquarters in Cambridge to anchor its efforts to advance a drug that aims to treat amyotrophic lateral sclerosis (ALS).
  • QurAlis has raised seed funding from a syndicate featuring Amgen Ventures. The start-up will use the cash to advance treatments for three subtypes of amyotrophic lateral sclerosis (ALS). Amgen joined with MP Healthcare Venture Management and Alexandria Venture Investments to put the latest tranche of funding into QurAlis, which bankrolled its early days using money from friends and family investors. Bringing the new investors on board equips QurAlis to advance programs based on an understanding of the genetics and biomarkers associated with different types of ALS.

Market Competition              

Key players in the Amyotrophic Lateral Sclerosis market are Mitsubishi Tanabe Pharma Corporation; Otsuka Pharmaceutical Co., Ltd.; BrainStorm Therapeutics; Biogen Inc.; Corestem; AB Science; F.Hoffmann-La Roche AG; Biohaven Pharmaceutical; Sun Pharmaceutical; and Ionis Pharmaceuticals, Inc.

  • In June 2021, CRISPR Therapeutics and Capsida Biotherapeutics Inc. entered into a strategic partnership to research, develop, manufacture, and commercialize in vivo gene editing therapies using CRISPR technology delivered with engineered AAV vectors for the treatment of familial amyotrophic lateral sclerosis (ALS) and Friedreich’s ataxia. Such partnerships are likely to bolster market growth.
  • In June 2022, Canada approved Amylyx Pharmaceuticals Inc’s new drug ALBRIOZA (also known as AMX0035) for amyotrophic lateral sclerosis.

Report Scope

Report Attribute Details
Market Value in 2023 US$ 743.90 Million
Market Value in 2033 US$ 1332.22 Million
Growth Rate CAGR of 6% from 2023 to 2033
Base Year for Estimation 2022
Historical Data 2017 to 2022
Forecast Period 2023 to 2033
Quantitative Units Revenue in USD Million and CAGR from 2023 to 2033
Report Coverage Revenue Forecast, Volume Forecast, Company Ranking, Competitive Landscape, Growth Factors, Trends, and Pricing Analysis
Segments Covered
  • Treatment
  • Distribution Channel
  • Region
Regions Covered
  • North America
  • Latin America
  • Europe
  • Asia Pacific
  • Middle East and Africa (MEA)
Key Countries Profiled
  • USA
  • Canada
  • Brazil
  • Argentina
  • Germany
  • UK
  • France
  • Spain
  • Italy
  • Nordics
  • BENELUX
  • Australia & New Zealand
  • China
  • India
  • ASIAN
  • GCC Countries
  • South Africa
Key Companies Profiled
  • Mitsubishi Tanabe Pharma Corporation
  • Otsuka Pharmaceutical Co., Ltd.
  • BrainStorm Therapeutics
  • Biogen Inc.
  • Corestem
  • AB Science
  • F.Hoffmann-La Roche AG
  • Biohaven Pharmaceutical
  • Sun Pharmaceutical
  • Ionis Pharmaceuticals, Inc.
Customization Available Upon Request

Key Segments Profiled in the Amyotrophic Lateral Sclerosis Industry Survey

Treatment:

  • Medication
  • Stem Cell Therapy
  • Others

Distribution Channel:

  • Hospital Pharmacies
  • Retail Pharmacies
  • Others

Region:

  • North America
  • Latin America
  • Europe
  • Asia Pacific
  • Middle East and Africa (MEA)

Frequently Asked Questions

At what rate did the Amyotrophic Lateral Sclerosis market flourish from 2017 to 2022?

From 2017 to 2022, the Amyotrophic Lateral Sclerosis market grew at a CAGR of 4%.

What will be the growth rate of the global Amyotrophic Lateral Sclerosis market during the forecast period?

The global Amyotrophic Lateral Sclerosis market is expected to grow with a 6% CAGR from 2023 to 2033.

What will be the projected market size of the Amyotrophic Lateral Sclerosis market by 2033?

As of 2033, the Amyotrophic Lateral Sclerosis market is expected to reach US$ 1332.22 Million

Which distribution segment is expected to dominate the global Amyotrophic Lateral Sclerosis market during 2033?

According to the FMI analysis, Hospital pharmacies account for the largest market share.

Which type of treatment is expected to dominate the global Amyotrophic Lateral Sclerosis market during 2033?

Stem cell therapy is expected to show the highest CAGR owing to the increasing demand for new approaches.

How is the North America Amyotrophic Lateral Sclerosis market projected to grow in 2033?

North America is expected to possess 20% market share for Amyotrophic Lateral Sclerosis market.

How is the Asia Pacific Amyotrophic Lateral Sclerosis market projected to grow in 2033?

The Asia Pacific market is predicted to increase significantly throughout the forecast period, with a CAGR of 5% during the forecast period.

Table of Content

1. Executive Summary | Amyotrophic Lateral Sclerosis Market

    1.1. Global Market Outlook

    1.2. Demand-side Trends

    1.3. Supply-side Trends

    1.4. Technology Roadmap Analysis

    1.5. Analysis and Recommendations

2. Market Overview

    2.1. Market Coverage / Taxonomy

    2.2. Market Definition / Scope / Limitations

3. Market Background

    3.1. Market Dynamics

        3.1.1. Drivers

        3.1.2. Restraints

        3.1.3. Opportunity

        3.1.4. Trends

    3.2. Scenario Forecast

        3.2.1. Demand in Optimistic Scenario

        3.2.2. Demand in Likely Scenario

        3.2.3. Demand in Conservative Scenario

    3.3. Opportunity Map Analysis

    3.4. Investment Feasibility Matrix

    3.5. PESTLE and Porter’s Analysis

    3.6. Regulatory Landscape

        3.6.1. By Key Regions

        3.6.2. By Key Countries

    3.7. Regional Parent Market Outlook

4. Global Market Analysis 2018 to 2022 and Forecast, 2023 to 2033

    4.1. Historical Market Size Value (US$ Million) Analysis, 2018 to 2022

    4.2. Current and Future Market Size Value (US$ Million) Projections, 2023 to 2033

        4.2.1. Y-o-Y Growth Trend Analysis

        4.2.2. Absolute $ Opportunity Analysis

5. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Treatment

    5.1. Introduction / Key Findings

    5.2. Historical Market Size Value (US$ Million) Analysis By Treatment, 2018 to 2022

    5.3. Current and Future Market Size Value (US$ Million) Analysis and Forecast By Treatment, 2023 to 2033

        5.3.1. Medication

        5.3.2. Stem Cell Therapy

        5.3.3. Others

    5.4. Y-o-Y Growth Trend Analysis By Treatment, 2018 to 2022

    5.5. Absolute $ Opportunity Analysis By Treatment, 2023 to 2033

6. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Distribution Channel

    6.1. Introduction / Key Findings

    6.2. Historical Market Size Value (US$ Million) Analysis By Distribution Channel, 2018 to 2022

    6.3. Current and Future Market Size Value (US$ Million) Analysis and Forecast By Distribution Channel, 2023 to 2033

        6.3.1. Hospital Pharmacies

        6.3.2. Retail Pharmacies

        6.3.3. Others

    6.4. Y-o-Y Growth Trend Analysis By Distribution Channel, 2018 to 2022

    6.5. Absolute $ Opportunity Analysis By Distribution Channel, 2023 to 2033

7. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Region

    7.1. Introduction

    7.2. Historical Market Size Value (US$ Million) Analysis By Region, 2018 to 2022

    7.3. Current Market Size Value (US$ Million) Analysis and Forecast By Region, 2023 to 2033

        7.3.1. North America

        7.3.2. Latin America

        7.3.3. Europe

        7.3.4. Asia Pacific

        7.3.5. Middle East and Africa (MEA)

    7.4. Market Attractiveness Analysis By Region

8. North America Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country

    8.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022

    8.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033

        8.2.1. By Country

            8.2.1.1. United States of America

            8.2.1.2. Canada

        8.2.2. By Treatment

        8.2.3. By Distribution Channel

    8.3. Market Attractiveness Analysis

        8.3.1. By Country

        8.3.2. By Treatment

        8.3.3. By Distribution Channel

    8.4. Key Takeaways

9. Latin America Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country

    9.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022

    9.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033

        9.2.1. By Country

            9.2.1.1. Brazil

            9.2.1.2. Mexico

            9.2.1.3. Rest of Latin America

        9.2.2. By Treatment

        9.2.3. By Distribution Channel

    9.3. Market Attractiveness Analysis

        9.3.1. By Country

        9.3.2. By Treatment

        9.3.3. By Distribution Channel

    9.4. Key Takeaways

10. Europe Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country

    10.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022

    10.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033

        10.2.1. By Country

            10.2.1.1. Germany

            10.2.1.2. United Kingdom

            10.2.1.3. France

            10.2.1.4. Spain

            10.2.1.5. Italy

            10.2.1.6. Rest of Europe

        10.2.2. By Treatment

        10.2.3. By Distribution Channel

    10.3. Market Attractiveness Analysis

        10.3.1. By Country

        10.3.2. By Treatment

        10.3.3. By Distribution Channel

    10.4. Key Takeaways

11. Asia Pacific Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country

    11.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022

    11.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033

        11.2.1. By Country

            11.2.1.1. China

            11.2.1.2. Japan

            11.2.1.3. South Korea

            11.2.1.4. Singapore

            11.2.1.5. Thailand

            11.2.1.6. Indonesia

            11.2.1.7. Australia

            11.2.1.8. New Zealand

            11.2.1.9. Rest of Asia Pacific

        11.2.2. By Treatment

        11.2.3. By Distribution Channel

    11.3. Market Attractiveness Analysis

        11.3.1. By Country

        11.3.2. By Treatment

        11.3.3. By Distribution Channel

    11.4. Key Takeaways

12. MEA Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country

    12.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022

    12.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033

        12.2.1. By Country

            12.2.1.1. GCC Countries

            12.2.1.2. South Africa

            12.2.1.3. Israel

            12.2.1.4. Rest of MEA

        12.2.2. By Treatment

        12.2.3. By Distribution Channel

    12.3. Market Attractiveness Analysis

        12.3.1. By Country

        12.3.2. By Treatment

        12.3.3. By Distribution Channel

    12.4. Key Takeaways

13. Key Countries Market Analysis

    13.1. United States of America

        13.1.1. Pricing Analysis

        13.1.2. Market Share Analysis, 2022

            13.1.2.1. By Treatment

            13.1.2.2. By Distribution Channel

    13.2. Canada

        13.2.1. Pricing Analysis

        13.2.2. Market Share Analysis, 2022

            13.2.2.1. By Treatment

            13.2.2.2. By Distribution Channel

    13.3. Brazil

        13.3.1. Pricing Analysis

        13.3.2. Market Share Analysis, 2022

            13.3.2.1. By Treatment

            13.3.2.2. By Distribution Channel

    13.4. Mexico

        13.4.1. Pricing Analysis

        13.4.2. Market Share Analysis, 2022

            13.4.2.1. By Treatment

            13.4.2.2. By Distribution Channel

    13.5. Germany

        13.5.1. Pricing Analysis

        13.5.2. Market Share Analysis, 2022

            13.5.2.1. By Treatment

            13.5.2.2. By Distribution Channel

    13.6. United Kingdom

        13.6.1. Pricing Analysis

        13.6.2. Market Share Analysis, 2022

            13.6.2.1. By Treatment

            13.6.2.2. By Distribution Channel

    13.7. France

        13.7.1. Pricing Analysis

        13.7.2. Market Share Analysis, 2022

            13.7.2.1. By Treatment

            13.7.2.2. By Distribution Channel

    13.8. Spain

        13.8.1. Pricing Analysis

        13.8.2. Market Share Analysis, 2022

            13.8.2.1. By Treatment

            13.8.2.2. By Distribution Channel

    13.9. Italy

        13.9.1. Pricing Analysis

        13.9.2. Market Share Analysis, 2022

            13.9.2.1. By Treatment

            13.9.2.2. By Distribution Channel

    13.10. China

        13.10.1. Pricing Analysis

        13.10.2. Market Share Analysis, 2022

            13.10.2.1. By Treatment

            13.10.2.2. By Distribution Channel

    13.11. Japan

        13.11.1. Pricing Analysis

        13.11.2. Market Share Analysis, 2022

            13.11.2.1. By Treatment

            13.11.2.2. By Distribution Channel

    13.12. South Korea

        13.12.1. Pricing Analysis

        13.12.2. Market Share Analysis, 2022

            13.12.2.1. By Treatment

            13.12.2.2. By Distribution Channel

    13.13. Singapore

        13.13.1. Pricing Analysis

        13.13.2. Market Share Analysis, 2022

            13.13.2.1. By Treatment

            13.13.2.2. By Distribution Channel

    13.14. Thailand

        13.14.1. Pricing Analysis

        13.14.2. Market Share Analysis, 2022

            13.14.2.1. By Treatment

            13.14.2.2. By Distribution Channel

    13.15. Indonesia

        13.15.1. Pricing Analysis

        13.15.2. Market Share Analysis, 2022

            13.15.2.1. By Treatment

            13.15.2.2. By Distribution Channel

    13.16. Australia

        13.16.1. Pricing Analysis

        13.16.2. Market Share Analysis, 2022

            13.16.2.1. By Treatment

            13.16.2.2. By Distribution Channel

    13.17. New Zealand

        13.17.1. Pricing Analysis

        13.17.2. Market Share Analysis, 2022

            13.17.2.1. By Treatment

            13.17.2.2. By Distribution Channel

    13.18. GCC Countries

        13.18.1. Pricing Analysis

        13.18.2. Market Share Analysis, 2022

            13.18.2.1. By Treatment

            13.18.2.2. By Distribution Channel

    13.19. South Africa

        13.19.1. Pricing Analysis

        13.19.2. Market Share Analysis, 2022

            13.19.2.1. By Treatment

            13.19.2.2. By Distribution Channel

    13.20. Israel

        13.20.1. Pricing Analysis

        13.20.2. Market Share Analysis, 2022

            13.20.2.1. By Treatment

            13.20.2.2. By Distribution Channel

14. Market Structure Analysis

    14.1. Competition Dashboard

    14.2. Competition Benchmarking

    14.3. Market Share Analysis of Top Players

        14.3.1. By Regional

        14.3.2. By Treatment

        14.3.3. By Distribution Channel

15. Competition Analysis

    15.1. Competition Deep Dive

        15.1.1. Mitsubishi Tanabe Pharma Corporation

            15.1.1.1. Overview

            15.1.1.2. Product Portfolio

            15.1.1.3. Profitability by Market Segments

            15.1.1.4. Sales Footprint

            15.1.1.5. Strategy Overview

                15.1.1.5.1. Marketing Strategy

        15.1.2. Otsuka Pharmaceutical Co., Ltd.

            15.1.2.1. Overview

            15.1.2.2. Product Portfolio

            15.1.2.3. Profitability by Market Segments

            15.1.2.4. Sales Footprint

            15.1.2.5. Strategy Overview

                15.1.2.5.1. Marketing Strategy

        15.1.3. BrainStorm Therapeutics

            15.1.3.1. Overview

            15.1.3.2. Product Portfolio

            15.1.3.3. Profitability by Market Segments

            15.1.3.4. Sales Footprint

            15.1.3.5. Strategy Overview

                15.1.3.5.1. Marketing Strategy

        15.1.4. Biogen Inc.

            15.1.4.1. Overview

            15.1.4.2. Product Portfolio

            15.1.4.3. Profitability by Market Segments

            15.1.4.4. Sales Footprint

            15.1.4.5. Strategy Overview

                15.1.4.5.1. Marketing Strategy

        15.1.5. Corestem

            15.1.5.1. Overview

            15.1.5.2. Product Portfolio

            15.1.5.3. Profitability by Market Segments

            15.1.5.4. Sales Footprint

            15.1.5.5. Strategy Overview

                15.1.5.5.1. Marketing Strategy

        15.1.6. AB Science

            15.1.6.1. Overview

            15.1.6.2. Product Portfolio

            15.1.6.3. Profitability by Market Segments

            15.1.6.4. Sales Footprint

            15.1.6.5. Strategy Overview

                15.1.6.5.1. Marketing Strategy

        15.1.7. F.Hoffmann-La Roche AG

            15.1.7.1. Overview

            15.1.7.2. Product Portfolio

            15.1.7.3. Profitability by Market Segments

            15.1.7.4. Sales Footprint

            15.1.7.5. Strategy Overview

                15.1.7.5.1. Marketing Strategy

        15.1.8. Biohaven Pharmaceutical

            15.1.8.1. Overview

            15.1.8.2. Product Portfolio

            15.1.8.3. Profitability by Market Segments

            15.1.8.4. Sales Footprint

            15.1.8.5. Strategy Overview

                15.1.8.5.1. Marketing Strategy

        15.1.9. Sun Pharmaceutical

            15.1.9.1. Overview

            15.1.9.2. Product Portfolio

            15.1.9.3. Profitability by Market Segments

            15.1.9.4. Sales Footprint

            15.1.9.5. Strategy Overview

                15.1.9.5.1. Marketing Strategy

        15.1.10. Ionis Pharmaceuticals, Inc.

            15.1.10.1. Overview

            15.1.10.2. Product Portfolio

            15.1.10.3. Profitability by Market Segments

            15.1.10.4. Sales Footprint

            15.1.10.5. Strategy Overview

                15.1.10.5.1. Marketing Strategy

16. Assumptions & Acronyms Used

17. Research Methodology

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