Global AL Amyloidosis Therapeutics Market Snapshot (2023 to 2033)

The global AL amyloidosis therapeutics market is slated to reach a valuation of US$ 2.25 billion by the end of 2023. According to Future Market Insights, the market is projected to rise at a 7.3% CAGR until 2033, being valued at US$ 4.56 billion.

The most common kind of systemic amyloidosis is the amyloid light chain (AL) amyloidosis, sometimes referred to as primary amyloidosis. Systemic light-chain (AL) amyloidosis was once thought to be an unstoppable deadly condition. The AL amyloidosis outlook was dismal prior to effective therapy for the fundamental plasma cell dyscrasia, with an average AL amyloidosis life expectancy of almost 13 months and to just 6 months for individuals with symptomatic cardiac dysfunction. Indicators of myocardial cell destruction and heart failure, that are exceedingly sensitive to cardiac dysfunction in amyloidosis, are the main focus of present AL amyloidosis staging techniques.

The purpose of AL amyloidosis therapy is to quickly decrease the plasma cell clone in order to increase amyloid reabsorption as well as restore organ function, hence enhancing patients' QOL, heart function, and survival. In the right patients, chemotherapy (both low and high dose) combined with autologous hematopoietic stem cell transplantation (ASCT) significantly lowers the formation of amyloid light chains. Melphalan, bortezomib and dexamethasone-based regimens should be used to treat patients who are ineligible for ASCT.

As one AL amyloidosis therapeutic approach, the National Comprehensive Cancer Network suggests high-dose melphalan followed by ASCT. Treatment for AL amyloidosis is very customized and should be focused on hematologic as well as cardiac response indicators as well as organ dysfunction, age, and regimen toxicity. Alkylator-based chemotherapy is beneficial for around two thirds of patients. Also, there are tests being conducted to determine the optimum way to use novel agents. Such developments are expected to people the demand in the market from 2023 to 2033.

Data Points Key Statistics
Anticipated Base Year Value (2022) US$ 2.1 billion
Expected Market Value (2023) US$ 2.25 billion
Projected Forecast Value (2033) US$ 4.56 billion
Global Growth Rate (2023 to 2033) 7.3%

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2018 To 2022 AL Amyloidosis Therapeutics Market Demand Analysis Vs. Forecast 2023 To 2033

The global AL amyloidosis therapeutics market grew at a CAGR of 5.2% from 2018 to 2022, as per Future Market Insights, a provider of market research and competitive intelligence. Although this condition is more common in adults above the age of 60 years and older, the growing geriatric population in both developed and emerging nations is also driving the demand in the global AL amyloidosis therapeutics market.

Also, the market for AL amyloidosis treatments is accelerating due to increased governmental and private sector funding, research, and development efforts. The development of healthcare technology and growing public awareness of rare illnesses are expected to support market expansion in the years to come. As a result, the global AL amyloidosis therapeutics market is expected to forecast a CAGR over 8% from 2023 to 2033.

Prominent Growth Drivers Influencing AL Amyloidosis Therapeutics Market

Various biological advancements used in this therapy is driving the market expansion

The market for AL amyloidosis therapeutics is largely being driven by the rise in incidences of mutations in blood cell DNA and the prevalence of underlying plasma cell illnesses such as monoclonal gammopathy and multiple myeloma of uncertain significance.

Also, the widespread use of amyloid stabilizers, which stabilize the amyloid protein and stop it from building up in tissues and organs, is supporting the market's expansion. Moreover, the increasing use of innovative treatments that target the underlying causes of AL amyloidosis, such as immunomodulatory medications, proteasome inhibitors, monoclonal antibodies, etc. has considerably increased patient response times and lengthened progression-free life. This in turn is serving as yet another important component that promotes development.

The market is also expanding owing to the rising demand for high-dose chemotherapy, accompanied by autologous transplantation of stem cells, as a therapeutic option for patients admitted with AL amyloidosis. This therapy tries to enhance organ function by removing aberrant cells that generate amyloid protein. Moreover, continual improvements in diagnostic methods, such as the development of serum-free light chain tests as well as mass spectrometry, have made it possible to make diagnoses sooner, enabling quicker treatment to begin and improved control of disease-related problems. Hence, the market for AL amyloidosis therapeutics is anticipated to grow throughout the course of the projected period.

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Sabyasachi Ghosh

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What Could Possibly Hinder AL Amyloidosis Therapeutics Market Demand? 

Lack of information and clinical studies is expected to impede the market growth

There is a shortage of epidemiological information on AL amyloidosis, and retrospective analysis reduces the validity of the data, which limits the market's potential growth. Additionally, the complex heterogeneity of the illnesses delays diagnosis, leading to severe disease (organ malfunction, including kidney, heart, and liver), lowering survival rates for AL amyloidosis, and acting as a roadblock to the expansion of the AL amyloidosis therapeutics market.

Clinical studies for AL amyloidosis therapeutics are also difficult to conduct successfully because of low patient recruitment as well as a lack of strictly delineated new outcomes. The participation of the kidney and heart systems results in expensive medical care. Moreover, the anticipated releases will probably cost more than myeloma-based medications, which may limit the accessibility and affordability of the AL amyloidosis therapies. Additionally, the function of upfront ASCT in various eligible patients has to be addressed in the era of daratumumab-based therapy. The aforementioned issues thus restrict the growth of the AL amyloidosis therapeutics market.

Region-wise Analysis

What Is the Outlook of the North American AL Amyloidosis Therapeutics Market?

Rising incidence of amyloidosis cases along with innovative products will boost the growth

During the forecast period, the North American market for AL amyloidosis therapeutics is expected to be the most volatile one. As per Future Market Insights, this region is expected to proliferate with a robust CAGR of 7.9% from 2023 to 2033.

The adoption of innovative therapies surged as a result of the prospective release of pipeline medications, and its dominating market share is also largely due to the high expense of healthcare in the United States. Around 3,900 new instances of AL amyloidosis are detected each year in the United States, making it the most prevalent kind.

This disease variant's diagnostic age is often in the mid-60s. Its yearly incidence in North American nations is roughly 15 instances per million persons, or about one-fifth that of myeloma, a blood cancer brought on by clonal plasma cells found in the bone marrow. Moreover, it can be challenging to diagnose since symptoms including weariness, paresthesia, edema, and weight loss frequently coexist with those of other prevalent illnesses. Hence, during the forecast period, the North American region can be expected to show a significant growth rate, acquiring a global market share of 39% in the year 2023.

What can Be expected from the Asia Pacific Market for AL Amyloidosis Therapeutics?

Enhanced healthcare facilities and strong patient pool to accelerate growth

During the forecast period, the Asia Pacific market for AL amyloidosis therapeutics is expected to garner a steady CAGR of 7.6%. The Asia Pacific AL amyloidosis therapeutics market is anticipated to grow quickly throughout the time of forecasting. This is because two of the three late-stage medications have received approval in Asia Pacific to treat amyloidosis. Due to supportive government policies, enhanced healthcare infrastructure, and greater investment, emerging markets for amyloidosis, such as China and India, are anticipated to have enticing development throughout the projection period.

The strong need for economical healthcare in these nations with big populations and low per capita incomes will fuel the growth of chemotherapy generic versions in this market. Alternatives for curative treatments with increased effectiveness are desperately needed. Hence, factors such as these are expected to accelerate the growth in the regional market from 2023 to 2033.

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Category-wise Insights

Which treatment segment is expected to gain traction from 2023 to 2033?

The chemotherapy segment will gain the dominant market share

Over the course of the forecast period, the chemotherapy segment by treatment type is anticipated to occupy a significant share of the global AL amyloidosis therapeutics market. In 2023, this category is anticipated to dominate with a 53% revenue share.

Anti-cancer treatments or chemotherapy are used to treat AL amyloidosis because they slow the proliferation of the aberrant cells that produce amyloid. Such factors are expected to accelerate the growth prospects for AL amyloidosis therapeutics from 2023 to 2033.

Which Distribution Channel is expected to gain traction during 2023 to 2033?

Hospital pharmacies segment will demand during the forecast period

Future Market Insights' study indicates that the hospital pharmacy segment would expand throughout the projected period. From 2023 to 2033, it is predicted that this market segment would have a 25% share of the global market.

Patients who are diagnosed with AL amyloidosis are mostly being treated in the hospitals under the supervision of the specialized doctors. With such patients, no doctor takes the risk of the treating them at home. Hence, as the treatment is being conducted in the hospitals itself, most of the medications and therapies are provided by the hospitals.

Start-up Scenario

The start-ups in this sector aim to use a number of techniques, such as the launch of new products and acquisitions, to improve their market positions internationally.

  • Attralus Therapeutics received $116 million in 2021 to launch a few amyloidosis treatments and a companion radiotracer diagnostic agent. This novel biotechnology is centered on treatments that amplify the immune system's capacity to eliminate amyloid. Amyloid disorders are a group of serious, frequently deadly ailments caused by an accumulation of the amyloid protein in essential tissues and organs.

How Competitive is the Market for AL amyloidosis therapeutics?

The launch of Darzalex Faspro by Genmab as well as Janssen Biotech, as well as AstraZeneca's purchase of Caelum Biosciences in 2021, are two examples of how significant industry players are increasing their understanding of the disease and working together. One of the main drivers of the AL amyloidosis therapeutics market growth is the strong pipeline with innovative, first-in-class medicines for the treatment of the disease.

Some of the important developments of the key players of the market are

  • A collaboration to explore CAEL-101 for light chain (AL) amyloidosis was announced in 2019 by Alexion Pharmaceuticals, Inc. and Caelum Biosciences. First-in-class and an amyloid fibril targeted treatment CAEL-101 is intended to enhance organ function in individuals with AL amyloidosis by decreasing or removing amyloid deposits. They think CAEL-101 has a great deal of potential to benefit these patients, and they're thrilled to include it in their expanding pipeline of rare hematological clinical-stage drugs.
  • Janssen Biotech disclosed in January 2021 that the Food and Drug Administration approved daratumumab with hyaluronidase in conjunction with bortezomib, dexamethasone and cyclophosphamide for recently diagnosed light chain (AL) amyloidosis. The Phase III ANDROMEDA study, which is testing daratumumab as well as hyaluronidase for the diagnosis of individuals who have newly diagnosed light chain (AL) amyloidosis, a rare blood cell disorder linked to the decline of vital organs, most noticeably the kidneys, heart, and liver, recently reported updated positive results.

Some of the prominent players in the global market for AL amyloidosis therapeutics are

  • Janssen Pharmaceutical
  • Prothena
  • Alexion Pharmaceuticals
  • Oncopeptides AB
  • Bristol-Myers Squibb
  • GlaxoSmithKline Pharmaceuticals Ltd
  • Celgene Corp
  • Eidos Therapeutics, Inc.
  • Corino Therapeutics, Inc.
  • Spectrum Pharmaceuticals, Inc.
  • Pfizer

Report Scope

Report Attribute Details
Growth Rate CAGR of 7.3% from 2023 to 2033
Market value in 2023 US$ 2.25 billion
Market value in 2033 US$ 4.56 billion
Base Year for Estimation 2022
Historical Data 2018 to 2022
Forecast Period 2023 to 2033
Quantitative Units US$ Billion for Value and CAGR from 2023 to 2033
Report Coverage Revenue Forecast, Company Ranking, Competitive Landscape, Growth Factors, Trends and Pricing Analysis
Segments Covered
  • Treatment
  • Drug
  • Distribution Channel
  • Region
Regions Covered
  • North America
  • Latin America
  • Europe
  • Asia Pacific
  • Middle East & Africa
Key Countries Profiled
  • United States
  • Canada
  • Brazil
  • Mexico
  • United Kingdom
  • Spain
  • Germany
  • Italy
  • France
  • Rest of Europe
  • China
  • Japan
  • South Korea
  • India
  • South Africa
  • GCC Countries
Key Companies Profiled
  • Janssen Pharmaceutical
  • Prothena
  • Alexion Pharmaceuticals
  • Oncopeptides AB
  • Bristol-Myers Squibb
  • GlaxoSmithKline Pharmaceuticals Ltd
  • Celgene Corp
  • Eidos Therapeutics, Inc.
  • Corino Therapeutics, Inc.
  • Spectrum Pharmaceuticals, Inc.
  • Pfizer
Customization Scope Available on Request

Key Segments Covered in the AL amyloidosis therapeutics market Report

By Treatment:

  • Chemotherapy
  • Supportive Care
  • Surgery
  • Stem Cell Transplant
  • Targeted Therapy

By Drugs:

  • Transthyretin Transport Inhibitor
  • Immunomodulatory Drugs
  • Monoclonal Antibodies
  • Proteasome Inhibitors
  • Others

By Distribution Channel:

  • Hospital Pharmacies
  • Retail Pharmacies
  • Online Pharmacies

By Region:

  • North America
  • Latin America
  • Europe
  • Asia Pacific
  • Middle East & Africa

Frequently Asked Questions

What is the Current Market Valuation?

The market is valued at US$ 2.25 billion in 2023.

How was the Market’s Historical Performance?

The market rose at a 5.2% CAGR from 2018 to 2022.

What is the Growth Forecast for the AL Amyloidosis Therapeutics Market?

The market is forecast to secure a CAGR of 7.3% through 2033.

What is the Expected Market Size in 2033?

The market is expected to reach US$ 4.56 billion by 2033.

What is North America's Projected CAGR until 2033?

North America is expected to accumulate a CAGR of 7.9% until 2033.

Table of Content
1. Executive Summary | AL Amyloidosis Therapeutics Market
    1.1. Global Market Outlook
    1.2. Demand-side Trends
    1.3. Supply-side Trends
    1.4. Technology Roadmap Analysis
    1.5. Analysis and Recommendations
2. Market Overview
    2.1. Market Coverage / Taxonomy
    2.2. Market Definition / Scope / Limitations
3. Market Background
    3.1. Market Dynamics
        3.1.1. Drivers
        3.1.2. Restraints
        3.1.3. Opportunity
        3.1.4. Trends
    3.2. Scenario Forecast
        3.2.1. Demand in Optimistic Scenario
        3.2.2. Demand in Likely Scenario
        3.2.3. Demand in Conservative Scenario
    3.3. Opportunity Map Analysis
    3.4. Investment Feasibility Matrix
    3.5. PESTLE and Porter’s Analysis
    3.6. Regulatory Landscape
        3.6.1. By Key Regions
        3.6.2. By Key Countries
    3.7. Regional Parent Market Outlook
4. Global Market Analysis 2018 to 2022 and Forecast, 2023 to 2033
    4.1. Historical Market Size Value (US$ Million) Analysis, 2018 to 2022
    4.2. Current and Future Market Size Value (US$ Million) Projections, 2023 to 2033
        4.2.1. Y-o-Y Growth Trend Analysis
        4.2.2. Absolute $ Opportunity Analysis
5. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Treatment
    5.1. Introduction / Key Findings
    5.2. Historical Market Size Value (US$ Million) Analysis By Treatment, 2018 to 2022
    5.3. Current and Future Market Size Value (US$ Million) Analysis and Forecast By Treatment, 2023 to 2033
        5.3.1. Chemotherapy
        5.3.2. Supportive Care
        5.3.3. Surgery
        5.3.4. Stem Cell Transplant
        5.3.5. Targeted Therapy
    5.4. Y-o-Y Growth Trend Analysis By Treatment, 2018 to 2022
    5.5. Absolute $ Opportunity Analysis By Treatment, 2023 to 2033
6. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Drugs
    6.1. Introduction / Key Findings
    6.2. Historical Market Size Value (US$ Million) Analysis By Drugs, 2018 to 2022
    6.3. Current and Future Market Size Value (US$ Million) Analysis and Forecast By Drugs, 2023 to 2033
        6.3.1. Transthyretin Transport Inhibitor
        6.3.2. Immunomodulatory Drugs
        6.3.3. Monoclonal Antibodies
        6.3.4. Proteasome Inhibitors
        6.3.5. Others
    6.4. Y-o-Y Growth Trend Analysis By Drugs, 2018 to 2022
    6.5. Absolute $ Opportunity Analysis By Drugs, 2023 to 2033
7. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Distribution Channel
    7.1. Introduction / Key Findings
    7.2. Historical Market Size Value (US$ Million) Analysis By Distribution Channel , 2018 to 2022
    7.3. Current and Future Market Size Value (US$ Million) Analysis and Forecast By Distribution Channel , 2023 to 2033
        7.3.1. Hospital Pharmacies
        7.3.2. Retail Pharmacies
        7.3.3. Online Pharmacies
    7.4. Y-o-Y Growth Trend Analysis By Distribution Channel , 2018 to 2022
    7.5. Absolute $ Opportunity Analysis By Distribution Channel , 2023 to 2033
8. Global Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Region
    8.1. Introduction
    8.2. Historical Market Size Value (US$ Million) Analysis By Region, 2018 to 2022
    8.3. Current Market Size Value (US$ Million) Analysis and Forecast By Region, 2023 to 2033
        8.3.1. North America
        8.3.2. Latin America
        8.3.3. Europe
        8.3.4. Asia Pacific
        8.3.5. Middle East and Africa
    8.4. Market Attractiveness Analysis By Region
9. North America Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
    9.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022
    9.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033
        9.2.1. By Country
            9.2.1.1. USA
            9.2.1.2. Canada
        9.2.2. By Treatment
        9.2.3. By Drugs
        9.2.4. By Distribution Channel
    9.3. Market Attractiveness Analysis
        9.3.1. By Country
        9.3.2. By Treatment
        9.3.3. By Drugs
        9.3.4. By Distribution Channel
    9.4. Key Takeaways
10. Latin America Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
    10.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022
    10.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033
        10.2.1. By Country
            10.2.1.1. Brazil
            10.2.1.2. Mexico
            10.2.1.3. Rest of Latin America
        10.2.2. By Treatment
        10.2.3. By Drugs
        10.2.4. By Distribution Channel
    10.3. Market Attractiveness Analysis
        10.3.1. By Country
        10.3.2. By Treatment
        10.3.3. By Drugs
        10.3.4. By Distribution Channel
    10.4. Key Takeaways
11. Europe Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
    11.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022
    11.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033
        11.2.1. By Country
            11.2.1.1. United kingdom
            11.2.1.2. Spain
            11.2.1.3. Germany
            11.2.1.4. Italy
            11.2.1.5. France
            11.2.1.6. Rest of Europe
        11.2.2. By Treatment
        11.2.3. By Drugs
        11.2.4. By Distribution Channel
    11.3. Market Attractiveness Analysis
        11.3.1. By Country
        11.3.2. By Treatment
        11.3.3. By Drugs
        11.3.4. By Distribution Channel
    11.4. Key Takeaways
12. Asia Pacific Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
    12.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022
    12.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033
        12.2.1. By Country
            12.2.1.1. China
            12.2.1.2. Japan
            12.2.1.3. India
            12.2.1.4. South Korea
            12.2.1.5. Rest of Asia Pacific
        12.2.2. By Treatment
        12.2.3. By Drugs
        12.2.4. By Distribution Channel
    12.3. Market Attractiveness Analysis
        12.3.1. By Country
        12.3.2. By Treatment
        12.3.3. By Drugs
        12.3.4. By Distribution Channel
    12.4. Key Takeaways
13. Middle East and Africa Market Analysis 2018 to 2022 and Forecast 2023 to 2033, By Country
    13.1. Historical Market Size Value (US$ Million) Trend Analysis By Market Taxonomy, 2018 to 2022
    13.2. Market Size Value (US$ Million) Forecast By Market Taxonomy, 2023 to 2033
        13.2.1. By Country
            13.2.1.1. South Africa
            13.2.1.2. GCC Countries
            13.2.1.3. Rest of Middle East and Africa
        13.2.2. By Treatment
        13.2.3. By Drugs
        13.2.4. By Distribution Channel
    13.3. Market Attractiveness Analysis
        13.3.1. By Country
        13.3.2. By Treatment
        13.3.3. By Drugs
        13.3.4. By Distribution Channel
    13.4. Key Takeaways
14. Key Countries Market Analysis
    14.1. USA
        14.1.1. Pricing Analysis
        14.1.2. Market Share Analysis, 2022
            14.1.2.1. By Treatment
            14.1.2.2. By Drugs
            14.1.2.3. By Distribution Channel
    14.2. Canada
        14.2.1. Pricing Analysis
        14.2.2. Market Share Analysis, 2022
            14.2.2.1. By Treatment
            14.2.2.2. By Drugs
            14.2.2.3. By Distribution Channel
    14.3. Brazil
        14.3.1. Pricing Analysis
        14.3.2. Market Share Analysis, 2022
            14.3.2.1. By Treatment
            14.3.2.2. By Drugs
            14.3.2.3. By Distribution Channel
    14.4. Mexico
        14.4.1. Pricing Analysis
        14.4.2. Market Share Analysis, 2022
            14.4.2.1. By Treatment
            14.4.2.2. By Drugs
            14.4.2.3. By Distribution Channel
    14.5. United kingdom
        14.5.1. Pricing Analysis
        14.5.2. Market Share Analysis, 2022
            14.5.2.1. By Treatment
            14.5.2.2. By Drugs
            14.5.2.3. By Distribution Channel
    14.6. Spain
        14.6.1. Pricing Analysis
        14.6.2. Market Share Analysis, 2022
            14.6.2.1. By Treatment
            14.6.2.2. By Drugs
            14.6.2.3. By Distribution Channel
    14.7. Germany
        14.7.1. Pricing Analysis
        14.7.2. Market Share Analysis, 2022
            14.7.2.1. By Treatment
            14.7.2.2. By Drugs
            14.7.2.3. By Distribution Channel
    14.8. Italy
        14.8.1. Pricing Analysis
        14.8.2. Market Share Analysis, 2022
            14.8.2.1. By Treatment
            14.8.2.2. By Drugs
            14.8.2.3. By Distribution Channel
    14.9. France
        14.9.1. Pricing Analysis
        14.9.2. Market Share Analysis, 2022
            14.9.2.1. By Treatment
            14.9.2.2. By Drugs
            14.9.2.3. By Distribution Channel
    14.10. China
        14.10.1. Pricing Analysis
        14.10.2. Market Share Analysis, 2022
            14.10.2.1. By Treatment
            14.10.2.2. By Drugs
            14.10.2.3. By Distribution Channel
    14.11. Japan
        14.11.1. Pricing Analysis
        14.11.2. Market Share Analysis, 2022
            14.11.2.1. By Treatment
            14.11.2.2. By Drugs
            14.11.2.3. By Distribution Channel
    14.12. India
        14.12.1. Pricing Analysis
        14.12.2. Market Share Analysis, 2022
            14.12.2.1. By Treatment
            14.12.2.2. By Drugs
            14.12.2.3. By Distribution Channel
    14.13. South Korea
        14.13.1. Pricing Analysis
        14.13.2. Market Share Analysis, 2022
            14.13.2.1. By Treatment
            14.13.2.2. By Drugs
            14.13.2.3. By Distribution Channel
    14.14. South Africa
        14.14.1. Pricing Analysis
        14.14.2. Market Share Analysis, 2022
            14.14.2.1. By Treatment
            14.14.2.2. By Drugs
            14.14.2.3. By Distribution Channel
    14.15. GCC Countries
        14.15.1. Pricing Analysis
        14.15.2. Market Share Analysis, 2022
            14.15.2.1. By Treatment
            14.15.2.2. By Drugs
            14.15.2.3. By Distribution Channel
15. Market Structure Analysis
    15.1. Competition Dashboard
    15.2. Competition Benchmarking
    15.3. Market Share Analysis of Top Players
        15.3.1. By Regional
        15.3.2. By Treatment
        15.3.3. By Drugs
        15.3.4. By Distribution Channel
16. Competition Analysis
    16.1. Competition Deep Dive
        16.1.1. Janssen Pharmaceutical
            16.1.1.1. Overview
            16.1.1.2. Product Portfolio
            16.1.1.3. Profitability by Market Segments
            16.1.1.4. Sales Footprint
            16.1.1.5. Strategy Overview
                16.1.1.5.1. Marketing Strategy
        16.1.2. Prothena
            16.1.2.1. Overview
            16.1.2.2. Product Portfolio
            16.1.2.3. Profitability by Market Segments
            16.1.2.4. Sales Footprint
            16.1.2.5. Strategy Overview
                16.1.2.5.1. Marketing Strategy
        16.1.3. Alexion Pharmaceuticals
            16.1.3.1. Overview
            16.1.3.2. Product Portfolio
            16.1.3.3. Profitability by Market Segments
            16.1.3.4. Sales Footprint
            16.1.3.5. Strategy Overview
                16.1.3.5.1. Marketing Strategy
        16.1.4. Oncopeptides AB
            16.1.4.1. Overview
            16.1.4.2. Product Portfolio
            16.1.4.3. Profitability by Market Segments
            16.1.4.4. Sales Footprint
            16.1.4.5. Strategy Overview
                16.1.4.5.1. Marketing Strategy
        16.1.5. Bristol-Myers Squibb
            16.1.5.1. Overview
            16.1.5.2. Product Portfolio
            16.1.5.3. Profitability by Market Segments
            16.1.5.4. Sales Footprint
            16.1.5.5. Strategy Overview
                16.1.5.5.1. Marketing Strategy
        16.1.6. GlaxoSmithKline Pharmaceuticals Ltd
            16.1.6.1. Overview
            16.1.6.2. Product Portfolio
            16.1.6.3. Profitability by Market Segments
            16.1.6.4. Sales Footprint
            16.1.6.5. Strategy Overview
                16.1.6.5.1. Marketing Strategy
        16.1.7. Celgene Corp
            16.1.7.1. Overview
            16.1.7.2. Product Portfolio
            16.1.7.3. Profitability by Market Segments
            16.1.7.4. Sales Footprint
            16.1.7.5. Strategy Overview
                16.1.7.5.1. Marketing Strategy
        16.1.8. Eidos Therapeutics, Inc.
            16.1.8.1. Overview
            16.1.8.2. Product Portfolio
            16.1.8.3. Profitability by Market Segments
            16.1.8.4. Sales Footprint
            16.1.8.5. Strategy Overview
                16.1.8.5.1. Marketing Strategy
        16.1.9. Corino Therapeutics, Inc.
            16.1.9.1. Overview
            16.1.9.2. Product Portfolio
            16.1.9.3. Profitability by Market Segments
            16.1.9.4. Sales Footprint
            16.1.9.5. Strategy Overview
                16.1.9.5.1. Marketing Strategy
        16.1.10. Spectrum Pharmaceuticals, Inc.
            16.1.10.1. Overview
            16.1.10.2. Product Portfolio
            16.1.10.3. Profitability by Market Segments
            16.1.10.4. Sales Footprint
            16.1.10.5. Strategy Overview
                16.1.10.5.1. Marketing Strategy
17. Assumptions & Acronyms Used
18. Research Methodology
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